Gene Symbol | Ap1s1 |
Entrez Gene ID | 11769 |
Full Name | adaptor protein complex AP-1, sigma 1 |
Synonyms | AP19 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ap1s1 cDNA ORF clone
Gene Symbol | Ap1s1 |
Entrez Gene ID | 11769 |
Full Name | adaptor protein complex AP-1, sigma 1 |
Synonyms | AP19 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_007457.2 | NP_031483.1 | AP-1 complex subunit sigma-1A |
NM_007457.3 | NP_031483.1 | AP-1 complex subunit sigma-1A |
XM_006504348.3 | XP_006504411.1 | AP-1 complex subunit sigma-1A isoform X1 |
XM_006504348.4 | XP_006504411.1 | AP-1 complex subunit sigma-1A isoform X1 |
Homo sapiens (human) | AP1S1 | NP_001274.1 |
Mus musculus (house mouse) | Ap1s1 | NP_031483.1 |
Rattus norvegicus (Norway rat) | Ap1s1 | NP_001101801.2 |
Xenopus tropicalis (tropical clawed frog) | ap1s1 | NP_989338.1 |
Danio rerio (zebrafish) | zgc:162858 | NP_001082809.1 |
Pan troglodytes (chimpanzee) | AP1S1 | XP_001153078.2 |
Bos taurus (cattle) | AP1S1 | NP_001070578.1 |
Canis lupus familiaris (dog) | AP1S1 | XP_003434784.1 |
AP-1/?1A and AP-1/?1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway.
Candiello E, Kratzke M, Wenzel D, Cassel D, Schu P
Scientific reports629950(2016 Jul)
?1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue.
Baltes J, Larsen JV, Radhakrishnan K, Geumann C, Kratzke M, Petersen CM, Schu P
Journal of cell science127(Pt 16)3477-87(2014 Aug)
Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: ?1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.
Moreno E, Moreno-Delgado D, Navarro G, Hoffmann HM, Fuentes S, Rosell-Vilar S, Gasperini P, Rodr?guez-Ruiz M, Medrano M, Mallol J, Cort?s A, Casad? V, Llu?s C, Ferr? S, Ortiz J, Canela E, McCormick PJ
The Journal of neuroscience : the official journal of the Society for Neuroscience34(10)3545-58(2014 Mar)
AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory.
Glyvuk N, Tsytsyura Y, Geumann C, D'Hooge R, H?ve J, Kratzke M, Baltes J, Boening D, B?ning D, Klingauf J, Schu P
The EMBO journal29(8)1318-30(2010 Apr)
The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site.
Doray B, Lee I, Knisely J, Bu G, Kornfeld S
Molecular biology of the cell18(5)1887-96(2007 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Ap1s1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ap1s1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu36103 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504348.3 , XM_006504348.4 | |
Accession Version | XM_006504348.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | AP-1 complex subunit sigma-1A isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504348.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTCAGA AGAAAGGTCA GGCCTTAGAG TGCACACCTG TAACCTGGTA CTCAGAGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504411.1 |
CDS | 941..1471 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504348.3 |
1 | ATGTCTCAGA AGAAAGGTCA GGCCTTAGAG TGCACACCTG TAACCTGGTA CTCAGAGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00206 | |
Clone ID Related Accession (Same CDS sequence) | NM_007457.2 , NM_007457.3 | |
Accession Version | NM_007457.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | AP-1 complex subunit sigma-1A | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC147986.3. On Nov 17, 2006 this sequence version replaced NM_007457.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M62418.1, BC052692.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGATGCGAT TCATGCTACT GTTCAGCCGG CAGGGAAAAC TTCGGCTACA AAAATGGTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031483.1 |
CDS | 51..527 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007457.2 |
1 | ATGATGCGAT TCATGCTACT GTTCAGCCGG CAGGGAAAAC TTCGGCTACA AAAATGGTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00206 | |
Clone ID Related Accession (Same CDS sequence) | NM_007457.2 , NM_007457.3 | |
Accession Version | NM_007457.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-30 | |
Organism | Mus musculus(house mouse) | |
Product | AP-1 complex subunit sigma-1A | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY253222.1 and BC052692.1. On Mar 28, 2018 this sequence version replaced NM_007457.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052692.1, M62418.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGCGAT TCATGCTACT GTTCAGCCGG CAGGGAAAAC TTCGGCTACA AAAATGGTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031483.1 |
CDS | 99..575 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007457.3 |
1 | ATGATGCGAT TCATGCTACT GTTCAGCCGG CAGGGAAAAC TTCGGCTACA AAAATGGTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36103 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504348.3 , XM_006504348.4 | |
Accession Version | XM_006504348.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | AP-1 complex subunit sigma-1A isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504348.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTCAGA AGAAAGGTCA GGCCTTAGAG TGCACACCTG TAACCTGGTA CTCAGAGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504411.1 |
CDS | 865..1395 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504348.4 |
1 | ATGTCTCAGA AGAAAGGTCA GGCCTTAGAG TGCACACCTG TAACCTGGTA CTCAGAGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
AP-1/?1A and AP-1/?1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway. |
?1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue. |
Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: ?1-D1-H3 receptor complexes as key targets for reducing cocaine's effects. |
AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory. |
The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site. |