Gene Symbol | Art1 |
Entrez Gene ID | 11870 |
Full Name | ADP-ribosyltransferase 1 |
Synonyms | ADPRT,ARTC1,Yac-1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Art1 cDNA ORF clone
Gene Symbol | Art1 |
Entrez Gene ID | 11870 |
Full Name | ADP-ribosyltransferase 1 |
Synonyms | ADPRT,ARTC1,Yac-1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011241657.1 | XP_011239959.1 | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 isoform X1 |
XM_011241657.2 | XP_011239959.1 | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 isoform X1 |
NM_009710.4 | NP_033840.2 | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 precursor |
Gallus gallus (chicken) | CHAT1 | NP_990444.1 |
Gallus gallus (chicken) | ART1 | NP_001029998.1 |
ART1 | XP_001113672.1 | |
Bos taurus (cattle) | ART1 | XP_002693475.1 |
Rattus norvegicus (Norway rat) | Art1 | NP_001101011.1 |
Gallus gallus (chicken) | ART7C | XP_003640650.1 |
Pan troglodytes (chimpanzee) | ART1 | XP_521725.1 |
Gallus gallus (chicken) | MADPRT | NP_001028818.1 |
Homo sapiens (human) | ART1 | NP_004305.2 |
Canis lupus familiaris (dog) | ART1 | XP_005633617.1 |
Mus musculus (house mouse) | Art1 | NP_033840.2 |
Gallus gallus (chicken) | CHAT2 | NP_990186.1 |
Gallus gallus (chicken) | ART7B | NP_001107976.1 |
Xenopus tropicalis (tropical clawed frog) | art1 | NP_001072682.1 |
Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in?vivo.
Xu JX, Xiong W, Zeng Z, Tang Y, Wang YL, Xiao M, Li M, Li QS, Song GL, Kuang J
Molecular medicine reports15(3)1222-1228(2017 Mar)
Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway.
Yang L, Xiao M, Li X, Tang Y, Wang YL
International journal of molecular medicine37(3)734-42(2016 Mar)
Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells.
Kuang J, Wang YL, Xiao M, Tang Y, Chen WW, Song GL, Yang X, Li M
Oncology reports31(5)2335-43(2014 May)
ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-?B pathway.
Xiao M, Tang Y, Wang YL, Yang L, Li X, Kuang J, Song GL
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology32(6)1587-99(2013)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The results demonstrated that ART1 gene silencing inhibited the growth of the spleen transplanted tumor and its ability to spread to the liver via metastasis.
Title: Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in?vivo.
data suggest that ART1 promoted the expression of HIF-1alpha via the Akt pathway in tumor cells.
Title: Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway.
the apoptosis rate in the ART1-cDNA CT26 cells treated with PARP-1 inhibitor 5-aminoisoquinoline (5-AIQ) and cisplatin increased, when compared with the ART1-cDNA CT26 cells treated with cisplatin only or the untreated ART1-cDNA CT26 cells.
Title: Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells.
ART1 knockdown reduced survival rate correlated with reduced levels of phos-Akt(Thr308) and phos-IkappaBalpha and reduced NF-kappaB p65 nuclear translocation.
Title: ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-?B pathway.
Successive amino- or carboxyl-terminal truncations of ART1, an arginine-specific transferase, identified regions that regulated transferase and NAD glycohydrolase activities.
Title: Identification of regulatory domains in ADP-ribosyltransferase-1 that determine transferase and NAD glycohydrolase activities.
The following Art1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Art1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu04694 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241657.1 , XM_011241657.2 , NM_009710.4 | |
Accession Version | NM_009710.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK003107.1. On Apr 5, 2007 this sequence version replaced NM_009710.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK003107.1, BC063760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAGATTC CTGCTATGAT GTCTCTCCTA CTGGTGTCTG TGGGTCTCAG GGATGGAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_033840.2 |
CDS | 93..1070 |
Translation |
Target ORF information:
Target ORF information:
|
NM_009710.4 |
1 | ATGAAGATTC CTGCTATGAT GTCTCTCCTA CTGGTGTCTG TGGGTCTCAG GGATGGAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu04694 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241657.1 , XM_011241657.2 , NM_009710.4 | |
Accession Version | XM_011241657.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGATTC CTGCTATGAT GTCTCTCCTA CTGGTGTCTG TGGGTCTCAG GGATGGAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239959.1 |
CDS | 118..1095 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011241657.1 |
1 | ATGAAGATTC CTGCTATGAT GTCTCTCCTA CTGGTGTCTG TGGGTCTCAG GGATGGAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu04694 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241657.1 , XM_011241657.2 , NM_009710.4 | |
Accession Version | XM_011241657.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011241657.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGATTC CTGCTATGAT GTCTCTCCTA CTGGTGTCTG TGGGTCTCAG GGATGGAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239959.1 |
CDS | 116..1093 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011241657.2 |
1 | ATGAAGATTC CTGCTATGAT GTCTCTCCTA CTGGTGTCTG TGGGTCTCAG GGATGGAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in?vivo. |
Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway. |
Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells. |
ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-?B pathway. |