Gene Symbol | Hoxb6 |
Entrez Gene ID | 15414 |
Full Name | homeobox B6 |
Synonyms | Hox-2.2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Hoxb6 cDNA ORF clone
Gene Symbol | Hoxb6 |
Entrez Gene ID | 15414 |
Full Name | homeobox B6 |
Synonyms | Hox-2.2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006532292.3 | XP_006532355.1 | homeobox protein Hox-B6 isoform X1 |
XM_006532292.4 | XP_006532355.1 | homeobox protein Hox-B6 isoform X1 |
NM_008269.1 | NP_032295.1 | homeobox protein Hox-B6 |
NM_008269.2 | NP_032295.1 | homeobox protein Hox-B6 |
Gallus gallus (chicken) | HOXB6 | XP_001236990.2 |
Bos taurus (cattle) | HOXB6 | XP_002695989.3 |
Rattus norvegicus (Norway rat) | Hoxb6 | XP_006247294.1 |
Canis lupus familiaris (dog) | HOXB6 | XP_003435306.1 |
Pan troglodytes (chimpanzee) | HOXB6 | XP_001172963.1 |
Danio rerio (zebrafish) | hoxb6a | NP_571194.1 |
Xenopus tropicalis (tropical clawed frog) | hoxb6 | XP_002938066.1 |
Homo sapiens (human) | HOXB6 | NP_061825.2 |
Mus musculus (house mouse) | Hoxb6 | NP_032295.1 |
Danio rerio (zebrafish) | hoxb6b | NP_571613.1 |
Interferon Regulatory Factor 6 Is Necessary for Salivary Glands and Pancreas Development.
Metwalli KA, Do MA, Nguyen K, Mallick S, Kin K, Farokhnia N, Jun G, Fakhouri WD
Journal of dental research97(2)226-236(2018 Feb)
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstr?m E, Pachnis V, Marklund U
Gastroenterology(2017 Oct)
New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.
Naruse C, Shibata S, Tamura M, Kawaguchi T, Abe K, Sugihara K, Kato T, Nishiuchi T, Wakana S, Ikawa M, Asano M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(6)2252-2266(2017 06)
PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes.
Endoh M, Endo TA, Shinga J, Hayashi K, Farcas A, Ma KW, Ito S, Sharif J, Endoh T, Onaga N, Nakayama M, Ishikura T, Masui O, Kessler BM, Suda T, Ohara O, Okuda A, Klose R, Koseki H
eLife6(2017 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results suggest the requirement of precisely regulated Hoxb6 expression for proper segmentation at tailbud stages.
Title: Hoxb6 can interfere with somitogenesis in the posterior embryo through a mechanism independent of its rib-promoting activity.
Hoxb6, in skeletal elements at the cervico-thoracic junction, controls multiple independent aspects of skeletal pattern, implicating discrete developmental pathways as substrates for this transcription factor.
Title: Developmental Patterning as a Quantitative Trait: Genetic Modulation of the Hoxb6 Mutant Skeletal Phenotype.
Hoxb6CreER(T) line provides a valuable tool for analyzing gene function, as well as lineage tracing studies using genetic cell marking, in several developing systems.
Title: Tamoxifen-dependent, inducible Hoxb6CreERT recombinase function in lateral plate and limb mesoderm, CNS isthmic organizer, posterior trunk neural crest, hindgut, and tailbud.
Altered Hox protein temporal and cellular balance of expression either contributes to pulmonary hypoplasia or functions as a compensatory mechanism attempting to correct abnormal lung development and maturation in this condition.
Title: Unique spatial and cellular expression patterns of Hoxa5, Hoxb4, and Hoxb6 proteins in normal developing murine lung are modified in pulmonary hypoplasia.
Overexpression of HOXB6 in marrow progenitors enhances self-renewal and cell growth in vitro. In vivo, it can result in acute myeloid leukemia with a median latency of 223 days.
Title: HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo.
The following Hoxb6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hoxb6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu01637 | |
Clone ID Related Accession (Same CDS sequence) | NM_008269.1 , NM_008269.2 | |
Accession Version | NM_008269.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Mus musculus(house mouse) | |
Product | homeobox protein Hox-B6 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC016893.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016893.1, AK011622.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAGTTCCT ATTTCGTGAA CTCCACCTTC CCCGTCACTC TGGCCAGCGG GCAGGAGTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032295.1 |
CDS | 7..681 |
Translation |
Target ORF information:
Target ORF information:
|
NM_008269.1 |
1 | ATGAGTTCCT ATTTCGTGAA CTCCACCTTC CCCGTCACTC TGGCCAGCGG GCAGGAGTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu01637 | |
Clone ID Related Accession (Same CDS sequence) | NM_008269.1 , NM_008269.2 | |
Accession Version | NM_008269.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-29 | |
Organism | Mus musculus(house mouse) | |
Product | homeobox protein Hox-B6 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL645478.15 and BE948571.1. On Feb 15, 2018 this sequence version replaced NM_008269.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016893.1, AK011622.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGTTCCT ATTTCGTGAA CTCCACCTTC CCCGTCACTC TGGCCAGCGG GCAGGAGTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032295.1 |
CDS | 104..778 |
Translation |
Target ORF information:
Target ORF information:
|
NM_008269.2 |
1 | ATGAGTTCCT ATTTCGTGAA CTCCACCTTC CCCGTCACTC TGGCCAGCGG GCAGGAGTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu45611 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532292.3 , XM_006532292.4 | |
Accession Version | XM_006532292.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | homeobox protein Hox-B6 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006532292.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAAATAT CAGAAAAGCG AAACAACCTC TCTCTCAAGT CTGAGAAGGG GAAACGACGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532355.1 |
CDS | 128..1057 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006532292.3 |
1 | ATGCAAATAT CAGAAAAGCG AAACAACCTC TCTCTCAAGT CTGAGAAGGG GAAACGACGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu45611 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532292.3 , XM_006532292.4 | |
Accession Version | XM_006532292.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | homeobox protein Hox-B6 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006532292.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAAATAT CAGAAAAGCG AAACAACCTC TCTCTCAAGT CTGAGAAGGG GAAACGACGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532355.1 |
CDS | 24..953 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006532292.4 |
1 | ATGCAAATAT CAGAAAAGCG AAACAACCTC TCTCTCAAGT CTGAGAAGGG GAAACGACGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Interferon Regulatory Factor 6 Is Necessary for Salivary Glands and Pancreas Development. |
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. |
New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice. |
PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. |