Stmn2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Stmn2
Entrez Gene ID	20257
Full Name	stathmin-like 2
Synonyms	AI159727,SCG10,Scgn10,Stmb2
General protein information	Preferred Names stathmin-like 2 Names stathmin-2 superior cervical ganglion-10 protein superiorcervical ganglia, neural specific 10
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3 A1\|3 2.15 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_025285.2	NP_079561.1	stathmin-2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	STMN2	XP_001167275.1
Canis lupus familiaris (dog)	STMN2	XP_860684.1
Danio rerio (zebrafish)	stmn2a	NP_001005923.2
Xenopus tropicalis (tropical clawed frog)	stmn2	NP_001005133.1
Danio rerio (zebrafish)	stmn2b	NP_001019393.1
Homo sapiens (human)	STMN2	NP_008960.2
Bos taurus (cattle)	STMN2	NP_001029794.1
Mus musculus (house mouse)	Stmn2	NP_079561.1
Gallus gallus (chicken)	STMN2	NP_990512.1
	STMN2	XP_001089780.1
Rattus norvegicus (Norway rat)	Stmn2	NP_445892.1

Gene Ontology
Bibliography

Related articles in PubMed

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.
Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, B?r S, Minocha S, Chevalier C, Po C, , Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, H?rault Y, Collins SC, Friant S, Godin JD, Yalcin B
Proceedings of the National Academy of Sciences of the United States of America114(44)E9308-E9317(2017 Oct)

Hedgehog signaling regulates ciliary localization of mouse odorant receptors.
Maurya DK, Bohm S, Alenius M
Proceedings of the National Academy of Sciences of the United States of America114(44)E9386-E9394(2017 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonstrated that axonal injury induces a dynamic regulation of SCG10 protein levels with selective accumulation in proximal axon segments.
Title: Dynamic regulation of SCG10 in regenerating axons after injury.

SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its trafficking to the cell surface.
Title: SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its trafficking to the cell surface.

JNK phosphorylation targets SCG10 for degradation.
Title: SCG10 is a JNK target in the axonal degeneration pathway.

These findings indicate that the phosphorylation of SCG10 by JNK1 is a fundamental mechanism that governs the transition from the multipolar stage and the rate of neuronal cell movement during cortical development.
Title: Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate.

SCG10 is not directly implicated in Hirschsprung diseased evelopment
Title: Mutations in SCG10 are not involved in Hirschsprung disease.

The following Stmn2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Stmn2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16592	NM_025285.2 Latest version!	Mus musculus stathmin-like 2 (Stmn2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Stmn2 ( NM_025285.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079561.1 Mus musculus stathmin-like 2 (Stmn2), mRNA.

Price & Availability↑

CloneID	OMu16592
Clone ID Related Accession (Same CDS sequence)	NM_025285.2
Accession Version	NM_025285.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	stathmin-2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC124554.5. On Nov 17, 2006 this sequence version replaced NM_025285.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK003659.1, AK149212.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGGCTAAAA CAGCAATGGC CTACAAGGAA AAAATGAAGG AGCTGTCTAT GCTGTCACTG 
ATCTGCTCCT GCTTCTACCC GGAGCCGCGC AACATCAACA TCTACACCTA CGACGACATG 
GAGGTGAAGC AGATCAACAA GCGGGCCTCT GGCCAGGCTT TTGAGCTGAT CTTGAAGCCA 
CCATCTCCCA TCTCAGAAGC TCCACGAACT CTAGCTTCTC CAAAGAAGAA AGACCTGTCT 
CTGGAGGAGA TTCAGAAAAA GCTGGAGGCT GCAGAGGAGC GAAGAAAGTC TCAAGAGGCT 
CAGGTGCTGA AGCAGTTGGC AGAGAAGAGG GAGCACGAGC GAGAGGTGCT CCAGAAGGCG 
CTGGAGGAGA ACAACAACTT CAGCAAGATG GCGGAGGAGA AGCTGATCCT GAAGATGGAA 
CAGATTAAGG AAAACCGTGA GGCTAATCTA GCTGCTATCA TTGAACGTCT GCAGGAAAAG 
GAGAGGCATG CTGCAGAGGT TCGCAGGAAC AAGGAACTGC AGGTTGAACT GTCTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079561.1
CDS	86..625
Translation	MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG

Target ORF information:

RefSeq Version	NM_025285.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus stathmin-like 2 (Stmn2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025285.2

ORF Insert Sequence:

ATGGCTAAAA CAGCAATGGC CTACAAGGAA AAAATGAAGG AGCTGTCTAT GCTGTCACTG 
ATCTGCTCCT GCTTCTACCC GGAGCCGCGC AACATCAACA TCTACACCTA CGACGACATG 
GAGGTGAAGC AGATCAACAA GCGGGCCTCT GGCCAGGCTT TTGAGCTGAT CTTGAAGCCA 
CCATCTCCCA TCTCAGAAGC TCCACGAACT CTAGCTTCTC CAAAGAAGAA AGACCTGTCT 
CTGGAGGAGA TTCAGAAAAA GCTGGAGGCT GCAGAGGAGC GAAGAAAGTC TCAAGAGGCT 
CAGGTGCTGA AGCAGTTGGC AGAGAAGAGG GAGCACGAGC GAGAGGTGCT CCAGAAGGCG 
CTGGAGGAGA ACAACAACTT CAGCAAGATG GCGGAGGAGA AGCTGATCCT GAAGATGGAA 
CAGATTAAGG AAAACCGTGA GGCTAATCTA GCTGCTATCA TTGAACGTCT GCAGGAAAAG 
GAGAGGCATG CTGCAGAGGT TCGCAGGAAC AAGGAACTGC AGGTTGAACT GTCTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.
Proceedings of the National Academy of Sciences of the United States of America114(44)E9308-E9317(2017 Oct)
Kannan M,Bayam E,Wagner C,Rinaldi B,Kretz PF,Tilly P,Roos M,McGillewie L,B?r S,Minocha S,Chevalier C,Po C,,Chelly J,Mandel JL,Borgatti R,Piton A,Kinnear C,Loos B,Adams DJ,H?rault Y,Collins SC,Friant S,Godin JD,Yalcin B

Hedgehog signaling regulates ciliary localization of mouse odorant receptors.
Proceedings of the National Academy of Sciences of the United States of America114(44)E9386-E9394(2017 Oct)
Maurya DK,Bohm S,Alenius M

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Stmn2 cDNA ORF clone, Mus musculus(house mouse)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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