Gene Symbol | Tiprl |
Entrez Gene ID | 226591 |
Full Name | TIP41, TOR signalling pathway regulator-like (S. cerevisiae) |
Synonyms | 1810011K17Rik |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Tiprl cDNA ORF clone
Gene Symbol | Tiprl |
Entrez Gene ID | 226591 |
Full Name | TIP41, TOR signalling pathway regulator-like (S. cerevisiae) |
Synonyms | 1810011K17Rik |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006496779.3 | XP_006496842.1 | TIP41-like protein isoform X1 |
NM_145513.4 | NP_663488.1 | TIP41-like protein isoform 1 |
XM_011238792.2 | XP_011237094.1 | TIP41-like protein isoform X2 |
XM_006496780.3 | XP_006496843.1 | TIP41-like protein isoform X2 |
XM_011238792.3 | XP_011237094.1 | TIP41-like protein isoform X1 |
NM_001357410.1 | NP_001344339.1 | TIP41-like protein isoform 2 |
NM_001357411.1 | NP_001344340.1 | TIP41-like protein isoform 3 |
Canis lupus familiaris (dog) | TIPRL | XP_537207.3 |
Rattus norvegicus (Norway rat) | Tiprl | NP_001103137.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002657 | XP_563488.3 |
Oryza sativa (rice) | Os03g0760600 | NP_001051346.1 |
Gallus gallus (chicken) | TIPRL | XP_416593.1 |
Eremothecium gossypii | AGOS_ACR174C | NP_983576.1 |
Neurospora crassa | NCU00109 | XP_957233.2 |
TIPRL | XP_001091944.2 | |
Danio rerio (zebrafish) | tiprl | NP_956957.1 |
Drosophila melanogaster (fruit fly) | CG9578 | NP_608377.1 |
Caenorhabditis elegans (roundworm) | ZK688.9 | NP_498713.3 |
Kluyveromyces lactis | KLLA0E06139g | XP_454223.1 |
Homo sapiens (human) | TIPRL | NP_690866.1 |
Pan troglodytes (chimpanzee) | TIPRL | XP_513978.3 |
Bos taurus (cattle) | TIPRL | NP_001073083.1 |
Mus musculus (house mouse) | Tiprl | NP_663488.1 |
Saccharomyces cerevisiae (baker's yeast) | TIP41 | NP_015365.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_00478 | XP_003718584.1 |
Arabidopsis thaliana (thale cress) | AT4G34270 | NP_195153.2 |
Xenopus tropicalis (tropical clawed frog) | tiprl | NP_001015736.1 |
Methylation-regulated decommissioning of multimeric PP2A complexes.
Wu CG, Zheng A, Jiang L, Rowse M, Stanevich V, Chen H, Li Y, Satyshur KA, Johnson B, Gu TJ, Liu Z, Xing Y
Nature communications8(1)2272(2017 Dec)
TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response.
Rosales KR, Reid MA, Yang Y, Tran TQ, Wang WI, Lowman X, Pan M, Kong M
PloS one10(12)e0145938(2015)
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
overexpression of TIPRL promotes phosphorylation of H2AX, and increases gamma-H2AX positive foci in response to DNA damage, whereas knockdown of TIPRL inhibits gamma-H2AX phosphorylation
Title: TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response.
The following Tiprl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tiprl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu28706 | |
Clone ID Related Accession (Same CDS sequence) | XM_011238792.2 , XM_006496780.3 , XM_011238792.3 , NM_001357411.1 | |
Accession Version | NM_001357411.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-22 | |
Organism | Mus musculus(house mouse) | |
Product | TIP41-like protein isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC154142.24. On Oct 27, 2017 this sequence version replaced XM_006496780.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.262903.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCCATCCC TCCCTGAAAT GATGTTTGGA GACAACGTTC TAAGGATCCA GCATGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001344340.1 |
CDS | 603..1295 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001357411.1 |
1 | ATGCCATCCC TCCCTGAAAT GATGTTTGGA GACAACGTTC TAAGGATCCA GCATGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu28706 | |
Clone ID Related Accession (Same CDS sequence) | XM_011238792.2 , XM_006496780.3 , XM_011238792.3 , NM_001357411.1 | |
Accession Version | XM_011238792.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | TIP41-like protein isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011238792.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATCCC TCCCTGAAAT GATGTTTGGA GACAACGTTC TAAGGATCCA GCATGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011237094.1 |
CDS | 245..937 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011238792.2 |
1 | ATGCCATCCC TCCCTGAAAT GATGTTTGGA GACAACGTTC TAAGGATCCA GCATGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu28706 | |
Clone ID Related Accession (Same CDS sequence) | XM_011238792.2 , XM_006496780.3 , XM_011238792.3 , NM_001357411.1 | |
Accession Version | XM_006496780.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(House mouse) | |
Product | TIP41-like protein isoform X2 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006496780.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATCCC TCCCTGAAAT GATGTTTGGA GACAACGTTC TAAGGATCCA GCATGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006496843.1 |
CDS | 647..1339 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006496780.3 |
1 | ATGCCATCCC TCCCTGAAAT GATGTTTGGA GACAACGTTC TAAGGATCCA GCATGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu28705 | |
Clone ID Related Accession (Same CDS sequence) | XM_006496779.3 , NM_001357410.1 | |
Accession Version | NM_001357410.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-22 | |
Organism | Mus musculus(house mouse) | |
Product | TIP41-like protein isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC154142.24. On Oct 27, 2017 this sequence version replaced XM_006496779.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.52739.1, SRR1660817.156055.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTGGAAAA GTGAGGCTGT GGGGCGGGGC CGGGCCGAGC CGAGCCGAGC CGAGCCGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001344339.1 |
CDS | 222..1001 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001357410.1 |
1 | ATGTGGAAAA GTGAGGCTGT GGGGCGGGGC CGGGCCGAGC CGAGCCGAGC CGAGCCGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu28705 | |
Clone ID Related Accession (Same CDS sequence) | XM_006496779.3 , NM_001357410.1 | |
Accession Version | XM_006496779.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(House mouse) | |
Product | TIP41-like protein isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006496779.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGGAAAA GTGAGGCTGT GGGGCGGGGC CGGGCCGAGC CGAGCCGAGC CGAGCCGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006496842.1 |
CDS | 268..1047 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006496779.3 |
1 | ATGTGGAAAA GTGAGGCTGT GGGGCGGGGC CGGGCCGAGC CGAGCCGAGC CGAGCCGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu11712 | |
Clone ID Related Accession (Same CDS sequence) | NM_145513.4 | |
Accession Version | NM_145513.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Mus musculus(house mouse) | |
Product | TIP41-like protein isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF531065.1 and AK049784.1. On May 16, 2009 this sequence version replaced NM_145513.3. ##Evidence-Data-START## Transcript exon combination :: AK049784.1, SRR1660817.247804.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGATCC ACGGCTTTCA GAGCAGCCAC CAGGACTTCT CCTTCGGGCC TTGGAAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_663488.1 |
CDS | 126..941 |
Translation |
Target ORF information:
Target ORF information:
|
NM_145513.4 |
1 | ATGATGATCC ACGGCTTTCA GAGCAGCCAC CAGGACTTCT CCTTCGGGCC TTGGAAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu28706 | |
Clone ID Related Accession (Same CDS sequence) | XM_011238792.2 , XM_006496780.3 , XM_011238792.3 , NM_001357411.1 | |
Accession Version | XM_011238792.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | TIP41-like protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011238792.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATCCC TCCCTGAAAT GATGTTTGGA GACAACGTTC TAAGGATCCA GCATGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011237094.1 |
CDS | 453..1145 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011238792.3 |
1 | ATGCCATCCC TCCCTGAAAT GATGTTTGGA GACAACGTTC TAAGGATCCA GCATGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Methylation-regulated decommissioning of multimeric PP2A complexes. |
TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response. |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |