Gene Symbol | Micall2 |
Entrez Gene ID | 231830 |
Full Name | MICAL-like 2 |
Synonyms | A930021H16Rik,JRAB,MICAL-L2,mFLJ00139 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Micall2 cDNA ORF clone
Gene Symbol | Micall2 |
Entrez Gene ID | 231830 |
Full Name | MICAL-like 2 |
Synonyms | A930021H16Rik,JRAB,MICAL-L2,mFLJ00139 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011240974.2 | XP_011239276.1 | MICAL-like protein 2 isoform X1 |
NM_174850.3 | NP_777275.2 | MICAL-like protein 2 |
XM_011240974.3 | XP_011239276.1 | MICAL-like protein 2 isoform X1 |
Mus musculus (house mouse) | Micall2 | NP_777275.2 |
Gallus gallus (chicken) | MICALL2 | XP_004945190.1 |
Xenopus tropicalis (tropical clawed frog) | micall2 | NP_001072513.1 |
Homo sapiens (human) | MICALL2 | NP_891554.1 |
MICALL2 | XP_001100629.2 | |
Canis lupus familiaris (dog) | MICALL2 | XP_005621229.1 |
Bos taurus (cattle) | MICALL2 | NP_001092402.1 |
Rattus norvegicus (Norway rat) | Micall2 | XP_006249037.1 |
EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.
Nakajo A, Yoshimura S, Togawa H, Kunii M, Iwano T, Izumi A, Noguchi Y, Watanabe A, Goto A, Sato T, Harada A
The Journal of cell biology212(3)297-306(2016 Feb)
Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.
Sakane A, Alamir Mahmoud Abdallah A, Nakano K, Honda K, Kitamura T, Imoto I, Matsushita N, Sasaki T
Genes to cells : devoted to molecular & cellular mechanisms18(9)810-22(2013 Sep)
Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2.
Sakane A, Honda K, Sasaki T
Molecular and cellular biology30(4)1077-87(2010 Feb)
Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions.
Nakatsuji H, Nishimura N, Yamamura R, Kanayama HO, Sasaki T
Molecular and cellular biology28(10)3324-35(2008 May)
The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.
Yamamura R, Nishimura N, Nakatsuji H, Arase S, Sasaki T
Molecular biology of the cell19(3)971-83(2008 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Interaction between JRAB and filamin regulates JRABDeltaCC-induced cell spreading.
Title: Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.
Rab13 and JRAB regulate reorganization of the actin cytoskeleton throughout epithelial junctional development.
Title: Rab13 small G protein and junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development.
show that Rab13 regulates neurite outgrowth in the rat pheochromocytoma cell line PC12 through an interaction with JRAB/MICAL-L2.
Title: Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2.
Although actinin-4 bound to JRAB/MICAL-L2 without Rab13, the actinin-4-JRAB/MICAL-L2 interaction was enhanced by Rab13 activation.
Title: Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions.
These results suggest that the interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.
Title: The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.
The following Micall2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Micall2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu73581 | |
Clone ID Related Accession (Same CDS sequence) | XM_011240974.2 , XM_011240974.3 | |
Accession Version | XM_011240974.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2781bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | MICAL-like protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011240974.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGCCT TGAAGGTTCC AGACCGGCTG AGCATTCTCA CCTATGTGTC ACAATACTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239276.1 |
CDS | 187..2967 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011240974.3 |
1 | ATGGTGGCCT TGAAGGTTCC AGACCGGCTG AGCATTCTCA CCTATGTGTC ACAATACTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu13156 | |
Clone ID Related Accession (Same CDS sequence) | NM_174850.3 | |
Accession Version | NM_174850.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3030bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | MICAL-like protein 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY346995.1, AB182579.1 and BY700282.1. On Jul 22, 2009 this sequence version replaced NM_174850.2. CCDS Note: The coding region has been updated to extend the N-terminus and to correct mismatches versus the reference genome assembly in the coding region which results in 4 aa changes to the C-terminus of the protein. This N-terminal extension is 114aa long, is supported by available conservation data and adds a CH (calponin homology) domain (SMART). ##Evidence-Data-START## Transcript exon combination :: AK151086.1, AK164043.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCCGCCA TAAAGGCCCT GCAAGAATGG TGCCGGCAGC AGTGCGAGGG CTACCGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_777275.2 |
CDS | 174..3203 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174850.3 |
1 | ATGGCCGCCA TAAAGGCCCT GCAAGAATGG TGCCGGCAGC AGTGCGAGGG CTACCGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu73581 | |
Clone ID Related Accession (Same CDS sequence) | XM_011240974.2 , XM_011240974.3 | |
Accession Version | XM_011240974.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2781bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | MICAL-like protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011240974.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGCCT TGAAGGTTCC AGACCGGCTG AGCATTCTCA CCTATGTGTC ACAATACTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239276.1 |
CDS | 184..2964 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011240974.2 |
1 | ATGGTGGCCT TGAAGGTTCC AGACCGGCTG AGCATTCTCA CCTATGTGTC ACAATACTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells. |
Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins. |
Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2. |
Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions. |
The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions. |