Gene Symbol | Rab8b |
Entrez Gene ID | 235442 |
Full Name | RAB8B, member RAS oncogene family |
Synonyms | 5930437D16,D330025I23Rik |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Rab8b cDNA ORF clone
Gene Symbol | Rab8b |
Entrez Gene ID | 235442 |
Full Name | RAB8B, member RAS oncogene family |
Synonyms | 5930437D16,D330025I23Rik |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_173413.3 | NP_775589.1 | ras-related protein Rab-8B |
XM_030244336.1 | XP_030100196.1 | ras-related protein Rab-8B isoform X1 |
Pan troglodytes (chimpanzee) | RAB8B | XP_510465.4 |
Mus musculus (house mouse) | Rab8b | NP_775589.1 |
Homo sapiens (human) | RAB8B | NP_057614.1 |
Canis lupus familiaris (dog) | RAB8B | XP_005638551.1 |
Rattus norvegicus (Norway rat) | Rab8b | NP_695229.1 |
Gallus gallus (chicken) | RAB8B | XP_004943799.1 |
Danio rerio (zebrafish) | rab8b | NP_001092729.1 |
Xenopus tropicalis (tropical clawed frog) | rab8b | NP_001090677.1 |
RAB8B | XP_002804851.1 | |
Bos taurus (cattle) | RAB8B | NP_001069785.1 |
Oryza sativa (rice) | Os07g0195100 | NP_001059115.1 |
Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis.
Azizoglu DB, Braitsch C, Marciano DK, Cleaver O
Genes & development31(23-24)2376-2390(2017 Dec)
Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis.
Burikhanov R, Hebbar N, Noothi SK, Shukla N, Sledziona J, Araujo N, Kudrimoti M, Wang QJ, Watt DS, Welch DR, Maranchie J, Harada A, Rangnekar VM
Cell reports18(2)508-519(2017 01)
Rab8b Regulates Transport of West Nile Virus Particles from Recycling Endosomes.
Kobayashi S, Suzuki T, Kawaguchi A, Phongphaew W, Yoshii K, Iwano T, Harada A, Kariwa H, Orba Y, Sawa H
The Journal of biological chemistry291(12)6559-68(2016 Mar)
Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis.
Sato T, Iwano T, Kunii M, Matsuda S, Mizuguchi R, Jung Y, Hagiwara H, Yoshihara Y, Yuzaki M, Harada R, Harada A
Journal of cell science127(Pt 2)422-31(2014 Jan)
TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation.
Pilli M, Arko-Mensah J, Ponpuak M, Roberts E, Master S, Mandell MA, Dupont N, Ornatowski W, Jiang S, Bradfute SB, Bruun JA, Hansen TE, Johansen T, Deretic V
Immunity37(2)223-34(2012 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rab8b is involved in trafficking of WNV particles from recycling endosomes to the plasma membrane.
Title: Rab8b Regulates Transport of West Nile Virus Particles from Recycling Endosomes.
Simultaneous loss of Rab8a and Rab8b has little effect on ciliogenesis, whereas additional loss of Rab10 greatly affects ciliogenesis.
Title: Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis.
Rab8b siRNA diminished autophagic killing of BCG, reduced the number of LC3 puncta in a high-content imaging analysis of cells stably expressing fluorescent protein fusion with LC3 and impeded basal clearance of the autophagic adaptor p62.
Title: TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation.
Otoferlin-Rab8b interaction links otoferlin to the basolateral endocytic and secretory trafficking.
Title: Rab8b GTPase, a protein transport regulator, is an interacting partner of otoferlin, defective in a human autosomal recessive deafness form.
These results suggest that the interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.
Title: The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.
The following Rab8b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rab8b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu04591 | |
Clone ID Related Accession (Same CDS sequence) | NM_173413.3 | |
Accession Version | NM_173413.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | ras-related protein Rab-8B | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY322741.1, BC059208.1 and AC142504.2. On Oct 24, 2009 this sequence version replaced NM_173413.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC059208.1, AK084650.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGAAGA CGTACGATTA TCTGTTCAAG CTGCTGCTCA TCGGCGACTC CGGCGTTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_775589.1 |
CDS | 73..696 |
Translation |
Target ORF information:
Target ORF information:
|
NM_173413.3 |
1 | ATGGCGAAGA CGTACGATTA TCTGTTCAAG CTGCTGCTCA TCGGCGACTC CGGCGTTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90178 | |
Clone ID Related Accession (Same CDS sequence) | XM_030244336.1 | |
Accession Version | XM_030244336.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ras-related protein Rab-8B isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGAATTA TGCTGGTCTA TGACATCACC AATGAAAAAT CCTTTGACAA TATTAAAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030100196.1 |
CDS | 470..850 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030244336.1 |
1 | ATGGGAATTA TGCTGGTCTA TGACATCACC AATGAAAAAT CCTTTGACAA TATTAAAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis. |
Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis. |
Rab8b Regulates Transport of West Nile Virus Particles from Recycling Endosomes. |
Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis. |
TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation. |