Gene Symbol | Ttc26 |
Entrez Gene ID | 264134 |
Full Name | tetratricopeptide repeat domain 26 |
Synonyms | 9330141E21Rik,9430097H08Rik,Ift56,hop,hpy |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ttc26 cDNA ORF clone
Gene Symbol | Ttc26 |
Entrez Gene ID | 264134 |
Full Name | tetratricopeptide repeat domain 26 |
Synonyms | 9330141E21Rik,9430097H08Rik,Ift56,hop,hpy |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_153600.2 | NP_705828.2 | intraflagellar transport protein 56 |
XM_006506152.3 | XP_006506215.1 | intraflagellar transport protein 56 isoform X1 |
XM_006506152.4 | XP_006506215.1 | intraflagellar transport protein 56 isoform X1 |
LOC715688 | XP_001106020.2 | |
Gallus gallus (chicken) | TTC26 | XP_004937740.1 |
Bos taurus (cattle) | TTC26 | XP_002687045.1 |
Drosophila melanogaster (fruit fly) | CG4525 | NP_650486.1 |
Caenorhabditis elegans (roundworm) | dyf-13 | NP_741021.1 |
Homo sapiens (human) | TTC26 | NP_079202.2 |
Pan troglodytes (chimpanzee) | TTC26 | XP_527905.3 |
Rattus norvegicus (Norway rat) | Ttc26 | NP_001020216.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001809 | XP_321248.5 |
Canis lupus familiaris (dog) | TTC26 | XP_003639595.2 |
Mus musculus (house mouse) | Ttc26 | NP_705828.2 |
Danio rerio (zebrafish) | ttc26 | NP_001008617.1 |
Xenopus tropicalis (tropical clawed frog) | ttc26 | NP_001096401.1 |
IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.
Xin D, Christopher KJ, Zeng L, Kong Y, Weatherbee SD
Development (Cambridge, England)144(8)1544-1553(2017 04)
A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling.
Swiderski RE, Nakano Y, Mullins RF, Seo S, B?nfi B
PLoS genetics10(10)e1004689(2014 Oct)
TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.
Ishikawa H, Ide T, Yagi T, Jiang X, Hirono M, Sasaki H, Yanagisawa H, Wemmer KA, Stainier DY, Qin H, Kamiya R, Marshall WF
eLife3e01566(2014 Jan)
Knockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells and the pronephros in zebrafish.
Zhang Q, Liu Q, Austin C, Drummond I, Pierce EA
Molecular biology of the cell23(16)3069-78(2012 Aug)
Characterization of mouse IFT complex B.
Follit JA, Xu F, Keady BT, Pazour GJ
Cell motility and the cytoskeleton66(8)457-68(2009 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These studies define a distinct and novel role for IFT56 in IFTB complex integrity that is crucial for cilia structure and function and, ultimately, animal development.
Title: IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.
Our analysis of the hop mouse line provides novel insights into Hh signaling, demonstrating that Ttc26 is necessary for efficient coupling between the accumulation of Gli at the ciliary tip and its dissociation from Sufu.
Title: A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling.
TTC26 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.
Title: TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.
Data show that Hop is expressed in airway epithelium coincident with HDAC2, and acts downstream of Nkx2.1 and GATA6, to negatively regulate surfactant protein expression.
Title: Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression.
The following Ttc26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ttc26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu37284 | |
Clone ID Related Accession (Same CDS sequence) | XM_006506152.3 , XM_006506152.4 | |
Accession Version | XM_006506152.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | intraflagellar transport protein 56 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006506152.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006506215.1 |
CDS | 118..1674 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006506152.3 |
1 | ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu02963 | |
Clone ID Related Accession (Same CDS sequence) | NM_153600.2 | |
Accession Version | NM_153600.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1665bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | intraflagellar transport protein 56 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC066060.1. On Feb 22, 2004 this sequence version replaced NM_153600.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC066060.1, AK035185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN00849385 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_705828.2 |
CDS | 68..1732 |
Translation |
Target ORF information:
Target ORF information:
|
NM_153600.2 |
1 | ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu37284 | |
Clone ID Related Accession (Same CDS sequence) | XM_006506152.3 , XM_006506152.4 | |
Accession Version | XM_006506152.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | intraflagellar transport protein 56 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006506152.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006506215.1 |
CDS | 128..1684 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006506152.4 |
1 | ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture. |
A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling. |
TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella. |
Knockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells and the pronephros in zebrafish. |
Characterization of mouse IFT complex B. |