Prdx6b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prdx6b
Entrez Gene ID	320769
Full Name	peroxiredoxin 6B
Synonyms	1-cysPrx-P1,4930414C22Rik,Aop2-rs1,Prdx5-rs1,Prdx6-ps1,Prdx6-rs1,Prdx6-rs1-ps
General protein information	Preferred Names peroxiredoxin 6B Names peroxiredoxin 6, related sequence 1 anti-oxidant protein 2 related sequence 1 peroxiredoxin 5 related sequence 1 peroxiredoxin 6, pseudogene 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 C3\|2 48.03 cM
Summary	This intronless gene is similar to the multi-exon peroxiredoxin 6 gene located on chromosome 1. It is transcribed and the ORF is intact compared to that of the peroxiredoxin 6 gene. This gene could be considered a transcribed pseudogene based on a failure to detect the protein in vivo in PMID:14644414. However, NCBI is representing the protein due to mass spectrometry data in PMID:18614015, which detected at least one peptide that is specific for this protein. [provided by RefSeq, Mar 2011].

mRNA and Protein(s)

mRNA	Protein	Name
NM_177256.5	NP_796230.1	peroxiredoxin 6, related sequence 1

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	TPX4	XP_320690.3
Drosophila melanogaster (fruit fly)	Prx2540-1	NP_724931.1
Drosophila melanogaster (fruit fly)	CG12896	NP_610584.2
Mus musculus (house mouse)	Prdx6b	NP_796230.1
Drosophila melanogaster (fruit fly)	Prx2540-2	NP_523683.1

Gene Ontology
Bibliography

Related articles in PubMed

1-Cys peroxiredoxin knock-out mice express mRNA but not protein for a highly related intronless gene.
Mo Y, Feinstein SI, Manevich Y, Zhang Q, Lu L, Ho YS, Fisher AB
FEBS letters555(2)192-8(2003 Dec)

Genetic mapping of six mouse peroxiredoxin genes and fourteen peroxiredoxin related sequences.
Lyu MS, Rhee SG, Chae HZ, Lee TH, Adamson MC, Kang SW, Jin DY, Jeang KT, Kozak CA
Mammalian genome : official journal of the International Mammalian Genome Society10(10)1017-9(1999 Oct)

Characterization of the murine gene encoding Aop2 (antioxidant protein 2) and identification of two highly related genes.
Phelan SA, Johnson KA, Beier DR, Paigen B
Genomics54(1)132-9(1998 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Prdx6b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prdx6b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu24745	NM_177256.5 Latest version!	Mus musculus peroxiredoxin 6B (Prdx6b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$146.30 $209.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prdx6b ( NM_177256.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_796230.1 Mus musculus peroxiredoxin 6B (Prdx6b), mRNA.

Price & Availability↑

CloneID	OMu24745
Clone ID Related Accession (Same CDS sequence)	NM_177256.5
Accession Version	NM_177256.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Mus musculus(house mouse)
Product	peroxiredoxin 6, related sequence 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL928587.7 and AK161395.1. On Mar 25, 2011 this sequence version replaced NM_177256.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript is intronless :: AK077012.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCGGAG GGTTGCTTCT CGGGGAAGAA GCCCCCGACT TTGAGGCCAA TACCACCATC 
GGCCGTATCC GCTTCCACGA TTTCCTGGGA AATTCATGGG GCATGCTCTT TTCCCACCCA 
AAGGACTTTA CCCCTGTGTG TACCACAGAA CTTGGTAGAG CTGCAAAGCT GGCGCCAGAG 
TTTGCCAAGA GGAATGTTAA GTTGATTGCA CTTTCAGTAG ATAGTGTTGA GGATCATCTT 
GCCTGGAGCA AGGACATCAA TGCTTACAAT GGTGCAACAC CCAAAGAAAA GTTGCCATTT 
CCCATCATTG ATGATAAGGA CAGGGACATT TCCATCCTTT TCTGCATGTT GGATCCAGTA 
GAGAAGGATG CTAACAGCAT GCCTCTGACG GCCCGGGGGG TGTTCATTTT TGGCCCTGAC 
AAGAAACTAA AGATGTCTCT CCTCTACCCT AACTCCACGG GCAGGAACTT TGATGAGATT 
CTCAGAGTGA TTGACTCTCT CCAGCTGACA GAAACAAAGC CGGTTGCCAC CCCAGTTGAT 
TGGAAGAAGG GAGAGAGCGT GATGGTCCTT CCCGACCTCC CCGAAGAGGA AGCCAAACGA 
TGTTTCCCTA AAGGAATCTC CACCACAAAG CTCCCGTCTG GCAAAAATTA CCTCCGTTAT 
ACACCCCAGC CTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_796230.1
CDS	380..1054
Translation	MPGGLLLGEEAPDFEANTTIGRIRFHDFLGNSWGMLFSHPKDFTPVCTTELGRAAKLAPEFAKRNVKLIALSVDSVEDHLAWSKDINAYNGATPKEKLPFPIIDDKDRDISILFCMLDPVEKDANSMPLTARGVFIFGPDKKLKMSLLYPNSTGRNFDEILRVIDSLQLTETKPVATPVDWKKGESVMVLPDLPEEEAKRCFPKGISTTKLPSGKNYLRYTPQP

Target ORF information:

RefSeq Version	NM_177256.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus peroxiredoxin 6B (Prdx6b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177256.5

ORF Insert Sequence:

ATGCCCGGAG GGTTGCTTCT CGGGGAAGAA GCCCCCGACT TTGAGGCCAA TACCACCATC 
GGCCGTATCC GCTTCCACGA TTTCCTGGGA AATTCATGGG GCATGCTCTT TTCCCACCCA 
AAGGACTTTA CCCCTGTGTG TACCACAGAA CTTGGTAGAG CTGCAAAGCT GGCGCCAGAG 
TTTGCCAAGA GGAATGTTAA GTTGATTGCA CTTTCAGTAG ATAGTGTTGA GGATCATCTT 
GCCTGGAGCA AGGACATCAA TGCTTACAAT GGTGCAACAC CCAAAGAAAA GTTGCCATTT 
CCCATCATTG ATGATAAGGA CAGGGACATT TCCATCCTTT TCTGCATGTT GGATCCAGTA 
GAGAAGGATG CTAACAGCAT GCCTCTGACG GCCCGGGGGG TGTTCATTTT TGGCCCTGAC 
AAGAAACTAA AGATGTCTCT CCTCTACCCT AACTCCACGG GCAGGAACTT TGATGAGATT 
CTCAGAGTGA TTGACTCTCT CCAGCTGACA GAAACAAAGC CGGTTGCCAC CCCAGTTGAT 
TGGAAGAAGG GAGAGAGCGT GATGGTCCTT CCCGACCTCC CCGAAGAGGA AGCCAAACGA 
TGTTTCCCTA AAGGAATCTC CACCACAAAG CTCCCGTCTG GCAAAAATTA CCTCCGTTAT 
ACACCCCAGC CTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

1-Cys peroxiredoxin knock-out mice express mRNA but not protein for a highly related intronless gene.
FEBS letters555(2)192-8(2003 Dec)
Mo Y,Feinstein SI,Manevich Y,Zhang Q,Lu L,Ho YS,Fisher AB

Genetic mapping of six mouse peroxiredoxin genes and fourteen peroxiredoxin related sequences.
Mammalian genome : official journal of the International Mammalian Genome Society10(10)1017-9(1999 Oct)
Lyu MS,Rhee SG,Chae HZ,Lee TH,Adamson MC,Kang SW,Jin DY,Jeang KT,Kozak CA

Characterization of the murine gene encoding Aop2 (antioxidant protein 2) and identification of two highly related genes.
Genomics54(1)132-9(1998 Nov)
Phelan SA,Johnson KA,Beier DR,Paigen B