Gene Symbol | Bpifb4 |
Entrez Gene ID | 381399 |
Full Name | BPI fold containing family B, member 4 |
Synonyms | Gm1006,Lplunc4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Bpifb4 cDNA ORF clone
Gene Symbol | Bpifb4 |
Entrez Gene ID | 381399 |
Full Name | BPI fold containing family B, member 4 |
Synonyms | Gm1006,Lplunc4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006499824.1 | XP_006499887.1 | BPI fold-containing family B member 4 isoform X1 |
NM_001034875.3 | NP_001030047.2 | BPI fold-containing family B member 4 precursor |
Bos taurus (cattle) | BPIFB4 | XP_003586861.2 |
Mus musculus (house mouse) | Bpifb4 | NP_001030047.2 |
Pan troglodytes (chimpanzee) | BPIFB4 | XP_525303.2 |
Rattus norvegicus (Norway rat) | Bpifb4 | NP_001102679.2 |
Homo sapiens (human) | BPIFB4 | NP_872325.2 |
Canis lupus familiaris (dog) | BPIFB4 | XP_534383.3 |
Gallus gallus (chicken) | BPIFB4 | XP_425718.4 |
A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.
Vecchione C, Villa F, Carrizzo A, Spinelli CC, Damato A, Ambrosio M, Ferrario A, Madonna M, Uccellatore A, Lupini S, Maciag A, Ryskalin L, Milanesi L, Frati G, Sciarretta S, Bellazzi R, Genovese S, Ceriello A, Auricchio A, Malovini A, Puca AA
Scientific reports7(1)9706(2017 Aug)
LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism.
Spinelli CC, Carrizzo A, Ferrario A, Villa F, Damato A, Ambrosio M, Madonna M, Frati G, Fucile S, Sciaccaluga M, Capunzo M, Cal? G, Milanesi L, Maciag A, Puca AA, Vecchione C
Cardiovascular research113(7)795-804(2017 Jun)
Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis.
Villa F, Carrizzo A, Spinelli CC, Ferrario A, Malovini A, Maci?g A, Damato A, Auricchio A, Spinetti G, Sangalli E, Dang Z, Madonna M, Ambrosio M, Sitia L, Bigini P, Cal? G, Schreiber S, Perls T, Fucile S, Mulas F, Nebel A, Bellazzi R, Madeddu P, Vecchione C, Puca AA
Circulation research117(4)333-45(2015 Jul)
Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily.
Bingle CD, Seal RL, Craven CJ
Biochemical Society transactions39(4)977-83(2011 Aug)
Phylogenetic and evolutionary analysis of the PLUNC gene family.
Bingle CD, LeClair EE, Havard S, Bingle L, Gillingham P, Craven CJ
Protein science : a publication of the Protein Society13(2)422-30(2004 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Bpifb4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bpifb4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu16163 | |
Clone ID Related Accession (Same CDS sequence) | XM_006499824.1 , NM_001034875.3 | |
Accession Version | NM_001034875.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1854bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | BPI fold-containing family B member 4 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX470156.7. On Feb 12, 2009 this sequence version replaced NM_001034875.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTGGACTG CGTGGTGTGT GGCTGCTCTG TCAGTGGCAG CTGTGTGTGG TATCCGCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001030047.2 |
CDS | 16..1869 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001034875.3 |
1 | ATGTGGACTG CGTGGTGTGT GGCTGCTCTG TCAGTGGCAG CTGTGTGTGG TATCCGCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu16163 | |
Clone ID Related Accession (Same CDS sequence) | XM_006499824.1 , NM_001034875.3 | |
Accession Version | XM_006499824.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1854bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | BPI fold-containing family B member 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGGACTG CGTGGTGTGT GGCTGCTCTG TCAGTGGCAG CTGTGTGTGG TATCCGCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006499887.1 |
CDS | 76..1929 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006499824.1 |
1 | ATGTGGACTG CGTGGTGTGT GGCTGCTCTG TCAGTGGCAG CTGTGTGTGG TATCCGCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling. |
LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism. |
Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis. |
Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. |
Phylogenetic and evolutionary analysis of the PLUNC gene family. |