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Ctps cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Ctps
Entrez Gene ID 51797
Full Name cytidine 5'-triphosphate synthase
Synonyms Ctps1
General protein information
Preferred Names

cytidine 5'-triphosphate synthase

Names

CTP synthase 1
CTP synthetase 1
UTP--ammonia ligase 1
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

4

4 D2.2|4 56.52 cM

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006503225.3 XP_006503288.1 CTP synthase 1 isoform X1
NM_001355491.1 NP_001342420.1 CTP synthase 1
NM_016748.2 NP_058028.2 CTP synthase 1

Pathways from BioSystems


Homologies


Homo sapiens (human) CTPS1 NP_001896.2
Mus musculus (house mouse) Ctps NP_058028.2
Rattus norvegicus (Norway rat) Ctps1 NP_001128345.1
Arabidopsis thaliana (thale cress) emb2742 NP_187873.1
Danio rerio (zebrafish) ctps1a NP_954681.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP009624 XP_318656.4
Oryza sativa (rice) Os01g0654100 NP_001043745.1
Xenopus tropicalis (tropical clawed frog) ctps1 XP_002939402.2
Pan troglodytes (chimpanzee) CTPS XP_524681.2
CTPS XP_001084608.2
Drosophila melanogaster (fruit fly) CTPsyn NP_730023.1
Oryza sativa (rice) Os05g0573300 NP_001056382.1
Canis lupus familiaris (dog) CTPS XP_005628921.1
Saccharomyces cerevisiae (baker's yeast) URA8 NP_012637.4
Bos taurus (cattle) CTPS NP_001071326.1
Gallus gallus (chicken) CTPS XP_004947749.1
Danio rerio (zebrafish) ctps1b NP_001104717.1
Danio rerio (zebrafish) LOC100535094 XP_003200276.1
Caenorhabditis elegans (roundworm) ctps-1 NP_507243.2

Gene Ontology


Bibliography

Related articles in PubMed

CTP synthase 1, a smooth muscle-sensitive therapeutic target for effective vascular repair.
Tang R, Cui XB, Wang JN, Chen SY
Arteriosclerosis, thrombosis, and vascular biology33(10)2336-44(2013 Oct)

Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.
Balzarini J, Gago F, Kulik W, van Kuilenburg AB, Karlsson A, Peterson MA, Robins MJ
The Journal of biological chemistry287(36)30444-54(2012 Aug)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CTPS1 inhibition selectively blocks smooth muscle cell proliferation without disturbing or even promoting re-endothelialization for effective vascular repair after injury.
Title: CTP synthase 1, a smooth muscle-sensitive therapeutic target for effective vascular repair.

Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.
Title: Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.

The following Ctps gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ctps cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu21440 NM_016748.2
Latest version!		 Mus musculus cytidine 5'-triphosphate synthase (Ctps), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OMu21440 NM_001355491.1
Latest version!		 Mus musculus cytidine 5'-triphosphate synthase (Ctps), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OMu21440 XM_006503225.3
Latest version!		 Mus musculus cytidine 5'-triphosphate synthase (Ctps), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone 40% OFF
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All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu21440
Clone ID Related Accession (Same CDS sequence) XM_006503225.3 , NM_001355491.1 , NM_016748.2
Accession Version NM_001355491.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1776bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-28
Organism Mus musculus(house mouse)
Product CTP synthase 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL611924.14, AK148259.1, AK161110.1 and CD363725.1. On Sep 18, 2017 this sequence version replaced XM_006503225.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.134806.1, SRR1660817.160314.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC 
AGCAGTGTGG GCACAATACT TAAATCATGT GGCTTACATG TAACATCAAT TAAGATTGAC 
CCCTATATTA ACATTGATGC AGGAACATTC TCTCCTTATG AACATGGAGA AGTCTTTGTG 
CTGGATGATG GTGGAGAAGT TGACCTTGAC TTGGGAAATT ATGAGCGATT CCTTGATATC 
CGTCTCACCA AGGACAATAA TCTGACCACA GGGAAGATAT ACCAGTACGT CATTAACAAG 
GAGCGCAAAG GGGATTACTT AGGGAAGACT GTCCAGGTTG TCCCTCACAT CACTGATGCA 
ATCCAAGAGT GGGTGATGAG ACAGGCATTA ATACCCGTAG ACGAAGATGG CTTAGAACCT 
CAAGTGTGTG TTATTGAGCT TGGTGGCACA GTGGGAGACA TTGAAAGCAT GCCCTTCATT 
GAGGCCTTCC GCCAGTTCCA GTTCAAGGTC AAGAGGGAAA ACTTTTGTAA TATCCATGTC 
AGTCTGGTTC CTCAGCCAAG TTCAACAGGG GAACAGAAGA CAAAACCCAC CCAGAACAGT 
GTTCGGGAAC TTAGAGGACT CGGGCTTTCT CCAGACTTAG TGGTGTGCAG GTGCTCAAAT 
CCTCTTGACA CATCTGTGAA AGAGAAAATA TCAATGTTTT GCCATGTGGA ACCTGAACAA 
GTGATCTGTG TTCATGATGT TTCATCCATC TACCGGGTAC CCTTGTTGTT AGAAGAGCAA 
GGGGTTGTAG ACTACTTTCT TCGGAGACTT GACCTTCCTA TTGAGAGACA GTCACGAAAG 
ATGCTGATGA AATGGAAAGA GATGGCAGAC AGGTATGACC GCTTGCTGGA GACCTGCTCG 
ATCGCTCTTG TGGGCAAATA CACCAAATTC TCAGACTCGT ACGCCTCTGT CATTAAAGCG 
CTAGAGCACT CTGCATTGGC CATTAACCAC AAGCTGGAGA TCAAGTACAT CGATTCCACA 
GACCTGGAGC CAAGTACCCT GCAGGAAGAG CCTGTGCGCT ACCATGAGGC ATGGCAGAAG 
CTCTGCAGTG CTCATGGAGT GCTGGTTCCA GGAGGATTTG GTGTTCGGGG AACAGAAGGA 
AAAATTCAAG CAATTGCTTG GGCTCGGAAA CAGAAGAAGC CTTTTTTGGG TGTGTGCTTA 
GGAATGCAGC TAGCAGTGGT AGAATTTTCA AGAAATGTGC TGGGATGGCA AGATGCCAAT 
TCTACAGAGT TTGACCCCAA GACTAGTCAC CCTGTGGTTA TAGACATGCC AGAACATAAC 
CCTGGGCAAA TGGGTGGAAC CATGAGGCTG GGCAAGAGGA GAACCCTGTT CCAGACCAAG 
AACTCAGTCA TGAGGAAACT CTATGGAGAC ACAGACTACT TGGAAGAAAG GCACCGCCAC 
CGATTTGAGG TGAACCCAGT CCTGAAAAAG TGCTTGGAAG AGCAAGGCTT GAAGTTCGTT 
GGCCAAGATG TGGAAGGCGA GAGGATGGAG ATCGTGGAGT TGGAAGATCA TCCATTTTTT 
GTTGGAGTGC AGTATCACCC CGAGTTCCTG TCCAGGCCTA TCAAGCCCTC CCCACCCTAC 
TTTGGCCTCC TCCTGGCCTC TGTGGGGCGG CTCCCACATT ACCTTCAGAA AGGTTGCCGG 
CTCTCACCCA GGGACACTTA CAGTGACAGA AGCGGGAGCA GCTCCCCCGA CTCGGAAATC 
ACTGAACTCA AGTTTCCATC AATAAGTCAG GACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001342420.1
CDS397..2172
Translation

Target ORF information:

RefSeq Version NM_001355491.1
Organism Mus musculus(house mouse)
Definition Mus musculus cytidine 5'-triphosphate synthase (Ctps), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001355491.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC 
AGCAGTGTGG GCACAATACT TAAATCATGT GGCTTACATG TAACATCAAT TAAGATTGAC 
CCCTATATTA ACATTGATGC AGGAACATTC TCTCCTTATG AACATGGAGA AGTCTTTGTG 
CTGGATGATG GTGGAGAAGT TGACCTTGAC TTGGGAAATT ATGAGCGATT CCTTGATATC 
CGTCTCACCA AGGACAATAA TCTGACCACA GGGAAGATAT ACCAGTACGT CATTAACAAG 
GAGCGCAAAG GGGATTACTT AGGGAAGACT GTCCAGGTTG TCCCTCACAT CACTGATGCA 
ATCCAAGAGT GGGTGATGAG ACAGGCATTA ATACCCGTAG ACGAAGATGG CTTAGAACCT 
CAAGTGTGTG TTATTGAGCT TGGTGGCACA GTGGGAGACA TTGAAAGCAT GCCCTTCATT 
GAGGCCTTCC GCCAGTTCCA GTTCAAGGTC AAGAGGGAAA ACTTTTGTAA TATCCATGTC 
AGTCTGGTTC CTCAGCCAAG TTCAACAGGG GAACAGAAGA CAAAACCCAC CCAGAACAGT 
GTTCGGGAAC TTAGAGGACT CGGGCTTTCT CCAGACTTAG TGGTGTGCAG GTGCTCAAAT 
CCTCTTGACA CATCTGTGAA AGAGAAAATA TCAATGTTTT GCCATGTGGA ACCTGAACAA 
GTGATCTGTG TTCATGATGT TTCATCCATC TACCGGGTAC CCTTGTTGTT AGAAGAGCAA 
GGGGTTGTAG ACTACTTTCT TCGGAGACTT GACCTTCCTA TTGAGAGACA GTCACGAAAG 
ATGCTGATGA AATGGAAAGA GATGGCAGAC AGGTATGACC GCTTGCTGGA GACCTGCTCG 
ATCGCTCTTG TGGGCAAATA CACCAAATTC TCAGACTCGT ACGCCTCTGT CATTAAAGCG 
CTAGAGCACT CTGCATTGGC CATTAACCAC AAGCTGGAGA TCAAGTACAT CGATTCCACA 
GACCTGGAGC CAAGTACCCT GCAGGAAGAG CCTGTGCGCT ACCATGAGGC ATGGCAGAAG 
CTCTGCAGTG CTCATGGAGT GCTGGTTCCA GGAGGATTTG GTGTTCGGGG AACAGAAGGA 
AAAATTCAAG CAATTGCTTG GGCTCGGAAA CAGAAGAAGC CTTTTTTGGG TGTGTGCTTA 
GGAATGCAGC TAGCAGTGGT AGAATTTTCA AGAAATGTGC TGGGATGGCA AGATGCCAAT 
TCTACAGAGT TTGACCCCAA GACTAGTCAC CCTGTGGTTA TAGACATGCC AGAACATAAC 
CCTGGGCAAA TGGGTGGAAC CATGAGGCTG GGCAAGAGGA GAACCCTGTT CCAGACCAAG 
AACTCAGTCA TGAGGAAACT CTATGGAGAC ACAGACTACT TGGAAGAAAG GCACCGCCAC 
CGATTTGAGG TGAACCCAGT CCTGAAAAAG TGCTTGGAAG AGCAAGGCTT GAAGTTCGTT 
GGCCAAGATG TGGAAGGCGA GAGGATGGAG ATCGTGGAGT TGGAAGATCA TCCATTTTTT 
GTTGGAGTGC AGTATCACCC CGAGTTCCTG TCCAGGCCTA TCAAGCCCTC CCCACCCTAC 
TTTGGCCTCC TCCTGGCCTC TGTGGGGCGG CTCCCACATT ACCTTCAGAA AGGTTGCCGG 
CTCTCACCCA GGGACACTTA CAGTGACAGA AGCGGGAGCA GCTCCCCCGA CTCGGAAATC 
ACTGAACTCA AGTTTCCATC AATAAGTCAG GACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu21440
Clone ID Related Accession (Same CDS sequence) XM_006503225.3 , NM_001355491.1 , NM_016748.2
Accession Version NM_016748.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1776bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-25
Organism Mus musculus(house mouse)
Product CTP synthase 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK146476.1, AK148259.1, AK161110.1 and CD363725.1. On Apr 4, 2008 this sequence version replaced NM_016748.1. Transcript Variant: This variant represents the shorter transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC006698.1, AK146476.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC 
AGCAGTGTGG GCACAATACT TAAATCATGT GGCTTACATG TAACATCAAT TAAGATTGAC 
CCCTATATTA ACATTGATGC AGGAACATTC TCTCCTTATG AACATGGAGA AGTCTTTGTG 
CTGGATGATG GTGGAGAAGT TGACCTTGAC TTGGGAAATT ATGAGCGATT CCTTGATATC 
CGTCTCACCA AGGACAATAA TCTGACCACA GGGAAGATAT ACCAGTACGT CATTAACAAG 
GAGCGCAAAG GGGATTACTT AGGGAAGACT GTCCAGGTTG TCCCTCACAT CACTGATGCA 
ATCCAAGAGT GGGTGATGAG ACAGGCATTA ATACCCGTAG ACGAAGATGG CTTAGAACCT 
CAAGTGTGTG TTATTGAGCT TGGTGGCACA GTGGGAGACA TTGAAAGCAT GCCCTTCATT 
GAGGCCTTCC GCCAGTTCCA GTTCAAGGTC AAGAGGGAAA ACTTTTGTAA TATCCATGTC 
AGTCTGGTTC CTCAGCCAAG TTCAACAGGG GAACAGAAGA CAAAACCCAC CCAGAACAGT 
GTTCGGGAAC TTAGAGGACT CGGGCTTTCT CCAGACTTAG TGGTGTGCAG GTGCTCAAAT 
CCTCTTGACA CATCTGTGAA AGAGAAAATA TCAATGTTTT GCCATGTGGA ACCTGAACAA 
GTGATCTGTG TTCATGATGT TTCATCCATC TACCGGGTAC CCTTGTTGTT AGAAGAGCAA 
GGGGTTGTAG ACTACTTTCT TCGGAGACTT GACCTTCCTA TTGAGAGACA GTCACGAAAG 
ATGCTGATGA AATGGAAAGA GATGGCAGAC AGGTATGACC GCTTGCTGGA GACCTGCTCG 
ATCGCTCTTG TGGGCAAATA CACCAAATTC TCAGACTCGT ACGCCTCTGT CATTAAAGCG 
CTAGAGCACT CTGCATTGGC CATTAACCAC AAGCTGGAGA TCAAGTACAT CGATTCCACA 
GACCTGGAGC CAAGTACCCT GCAGGAAGAG CCTGTGCGCT ACCATGAGGC ATGGCAGAAG 
CTCTGCAGTG CTCATGGAGT GCTGGTTCCA GGAGGATTTG GTGTTCGGGG AACAGAAGGA 
AAAATTCAAG CAATTGCTTG GGCTCGGAAA CAGAAGAAGC CTTTTTTGGG TGTGTGCTTA 
GGAATGCAGC TAGCAGTGGT AGAATTTTCA AGAAATGTGC TGGGATGGCA AGATGCCAAT 
TCTACAGAGT TTGACCCCAA GACTAGTCAC CCTGTGGTTA TAGACATGCC AGAACATAAC 
CCTGGGCAAA TGGGTGGAAC CATGAGGCTG GGCAAGAGGA GAACCCTGTT CCAGACCAAG 
AACTCAGTCA TGAGGAAACT CTATGGAGAC ACAGACTACT TGGAAGAAAG GCACCGCCAC 
CGATTTGAGG TGAACCCAGT CCTGAAAAAG TGCTTGGAAG AGCAAGGCTT GAAGTTCGTT 
GGCCAAGATG TGGAAGGCGA GAGGATGGAG ATCGTGGAGT TGGAAGATCA TCCATTTTTT 
GTTGGAGTGC AGTATCACCC CGAGTTCCTG TCCAGGCCTA TCAAGCCCTC CCCACCCTAC 
TTTGGCCTCC TCCTGGCCTC TGTGGGGCGG CTCCCACATT ACCTTCAGAA AGGTTGCCGG 
CTCTCACCCA GGGACACTTA CAGTGACAGA AGCGGGAGCA GCTCCCCCGA CTCGGAAATC 
ACTGAACTCA AGTTTCCATC AATAAGTCAG GACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_058028.2
CDS139..1914
Translation

Target ORF information:

RefSeq Version NM_016748.2
Organism Mus musculus(house mouse)
Definition Mus musculus cytidine 5'-triphosphate synthase (Ctps), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_016748.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC 
AGCAGTGTGG GCACAATACT TAAATCATGT GGCTTACATG TAACATCAAT TAAGATTGAC 
CCCTATATTA ACATTGATGC AGGAACATTC TCTCCTTATG AACATGGAGA AGTCTTTGTG 
CTGGATGATG GTGGAGAAGT TGACCTTGAC TTGGGAAATT ATGAGCGATT CCTTGATATC 
CGTCTCACCA AGGACAATAA TCTGACCACA GGGAAGATAT ACCAGTACGT CATTAACAAG 
GAGCGCAAAG GGGATTACTT AGGGAAGACT GTCCAGGTTG TCCCTCACAT CACTGATGCA 
ATCCAAGAGT GGGTGATGAG ACAGGCATTA ATACCCGTAG ACGAAGATGG CTTAGAACCT 
CAAGTGTGTG TTATTGAGCT TGGTGGCACA GTGGGAGACA TTGAAAGCAT GCCCTTCATT 
GAGGCCTTCC GCCAGTTCCA GTTCAAGGTC AAGAGGGAAA ACTTTTGTAA TATCCATGTC 
AGTCTGGTTC CTCAGCCAAG TTCAACAGGG GAACAGAAGA CAAAACCCAC CCAGAACAGT 
GTTCGGGAAC TTAGAGGACT CGGGCTTTCT CCAGACTTAG TGGTGTGCAG GTGCTCAAAT 
CCTCTTGACA CATCTGTGAA AGAGAAAATA TCAATGTTTT GCCATGTGGA ACCTGAACAA 
GTGATCTGTG TTCATGATGT TTCATCCATC TACCGGGTAC CCTTGTTGTT AGAAGAGCAA 
GGGGTTGTAG ACTACTTTCT TCGGAGACTT GACCTTCCTA TTGAGAGACA GTCACGAAAG 
ATGCTGATGA AATGGAAAGA GATGGCAGAC AGGTATGACC GCTTGCTGGA GACCTGCTCG 
ATCGCTCTTG TGGGCAAATA CACCAAATTC TCAGACTCGT ACGCCTCTGT CATTAAAGCG 
CTAGAGCACT CTGCATTGGC CATTAACCAC AAGCTGGAGA TCAAGTACAT CGATTCCACA 
GACCTGGAGC CAAGTACCCT GCAGGAAGAG CCTGTGCGCT ACCATGAGGC ATGGCAGAAG 
CTCTGCAGTG CTCATGGAGT GCTGGTTCCA GGAGGATTTG GTGTTCGGGG AACAGAAGGA 
AAAATTCAAG CAATTGCTTG GGCTCGGAAA CAGAAGAAGC CTTTTTTGGG TGTGTGCTTA 
GGAATGCAGC TAGCAGTGGT AGAATTTTCA AGAAATGTGC TGGGATGGCA AGATGCCAAT 
TCTACAGAGT TTGACCCCAA GACTAGTCAC CCTGTGGTTA TAGACATGCC AGAACATAAC 
CCTGGGCAAA TGGGTGGAAC CATGAGGCTG GGCAAGAGGA GAACCCTGTT CCAGACCAAG 
AACTCAGTCA TGAGGAAACT CTATGGAGAC ACAGACTACT TGGAAGAAAG GCACCGCCAC 
CGATTTGAGG TGAACCCAGT CCTGAAAAAG TGCTTGGAAG AGCAAGGCTT GAAGTTCGTT 
GGCCAAGATG TGGAAGGCGA GAGGATGGAG ATCGTGGAGT TGGAAGATCA TCCATTTTTT 
GTTGGAGTGC AGTATCACCC CGAGTTCCTG TCCAGGCCTA TCAAGCCCTC CCCACCCTAC 
TTTGGCCTCC TCCTGGCCTC TGTGGGGCGG CTCCCACATT ACCTTCAGAA AGGTTGCCGG 
CTCTCACCCA GGGACACTTA CAGTGACAGA AGCGGGAGCA GCTCCCCCGA CTCGGAAATC 
ACTGAACTCA AGTTTCCATC AATAAGTCAG GACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu21440
Clone ID Related Accession (Same CDS sequence) XM_006503225.3 , NM_001355491.1 , NM_016748.2
Accession Version XM_006503225.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1776bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(House mouse)
Product CTP synthase 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006503225.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC 
AGCAGTGTGG GCACAATACT TAAATCATGT GGCTTACATG TAACATCAAT TAAGATTGAC 
CCCTATATTA ACATTGATGC AGGAACATTC TCTCCTTATG AACATGGAGA AGTCTTTGTG 
CTGGATGATG GTGGAGAAGT TGACCTTGAC TTGGGAAATT ATGAGCGATT CCTTGATATC 
CGTCTCACCA AGGACAATAA TCTGACCACA GGGAAGATAT ACCAGTACGT CATTAACAAG 
GAGCGCAAAG GGGATTACTT AGGGAAGACT GTCCAGGTTG TCCCTCACAT CACTGATGCA 
ATCCAAGAGT GGGTGATGAG ACAGGCATTA ATACCCGTAG ACGAAGATGG CTTAGAACCT 
CAAGTGTGTG TTATTGAGCT TGGTGGCACA GTGGGAGACA TTGAAAGCAT GCCCTTCATT 
GAGGCCTTCC GCCAGTTCCA GTTCAAGGTC AAGAGGGAAA ACTTTTGTAA TATCCATGTC 
AGTCTGGTTC CTCAGCCAAG TTCAACAGGG GAACAGAAGA CAAAACCCAC CCAGAACAGT 
GTTCGGGAAC TTAGAGGACT CGGGCTTTCT CCAGACTTAG TGGTGTGCAG GTGCTCAAAT 
CCTCTTGACA CATCTGTGAA AGAGAAAATA TCAATGTTTT GCCATGTGGA ACCTGAACAA 
GTGATCTGTG TTCATGATGT TTCATCCATC TACCGGGTAC CCTTGTTGTT AGAAGAGCAA 
GGGGTTGTAG ACTACTTTCT TCGGAGACTT GACCTTCCTA TTGAGAGACA GTCACGAAAG 
ATGCTGATGA AATGGAAAGA GATGGCAGAC AGGTATGACC GCTTGCTGGA GACCTGCTCG 
ATCGCTCTTG TGGGCAAATA CACCAAATTC TCAGACTCGT ACGCCTCTGT CATTAAAGCG 
CTAGAGCACT CTGCATTGGC CATTAACCAC AAGCTGGAGA TCAAGTACAT CGATTCCACA 
GACCTGGAGC CAAGTACCCT GCAGGAAGAG CCTGTGCGCT ACCATGAGGC ATGGCAGAAG 
CTCTGCAGTG CTCATGGAGT GCTGGTTCCA GGAGGATTTG GTGTTCGGGG AACAGAAGGA 
AAAATTCAAG CAATTGCTTG GGCTCGGAAA CAGAAGAAGC CTTTTTTGGG TGTGTGCTTA 
GGAATGCAGC TAGCAGTGGT AGAATTTTCA AGAAATGTGC TGGGATGGCA AGATGCCAAT 
TCTACAGAGT TTGACCCCAA GACTAGTCAC CCTGTGGTTA TAGACATGCC AGAACATAAC 
CCTGGGCAAA TGGGTGGAAC CATGAGGCTG GGCAAGAGGA GAACCCTGTT CCAGACCAAG 
AACTCAGTCA TGAGGAAACT CTATGGAGAC ACAGACTACT TGGAAGAAAG GCACCGCCAC 
CGATTTGAGG TGAACCCAGT CCTGAAAAAG TGCTTGGAAG AGCAAGGCTT GAAGTTCGTT 
GGCCAAGATG TGGAAGGCGA GAGGATGGAG ATCGTGGAGT TGGAAGATCA TCCATTTTTT 
GTTGGAGTGC AGTATCACCC CGAGTTCCTG TCCAGGCCTA TCAAGCCCTC CCCACCCTAC 
TTTGGCCTCC TCCTGGCCTC TGTGGGGCGG CTCCCACATT ACCTTCAGAA AGGTTGCCGG 
CTCTCACCCA GGGACACTTA CAGTGACAGA AGCGGGAGCA GCTCCCCCGA CTCGGAAATC 
ACTGAACTCA AGTTTCCATC AATAAGTCAG GACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006503288.1
CDS668..2443
Translation

Target ORF information:

RefSeq Version XM_006503225.3
Organism Mus musculus(House mouse)
Definition Mus musculus cytidine 5'-triphosphate synthase (Ctps), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006503225.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC 
AGCAGTGTGG GCACAATACT TAAATCATGT GGCTTACATG TAACATCAAT TAAGATTGAC 
CCCTATATTA ACATTGATGC AGGAACATTC TCTCCTTATG AACATGGAGA AGTCTTTGTG 
CTGGATGATG GTGGAGAAGT TGACCTTGAC TTGGGAAATT ATGAGCGATT CCTTGATATC 
CGTCTCACCA AGGACAATAA TCTGACCACA GGGAAGATAT ACCAGTACGT CATTAACAAG 
GAGCGCAAAG GGGATTACTT AGGGAAGACT GTCCAGGTTG TCCCTCACAT CACTGATGCA 
ATCCAAGAGT GGGTGATGAG ACAGGCATTA ATACCCGTAG ACGAAGATGG CTTAGAACCT 
CAAGTGTGTG TTATTGAGCT TGGTGGCACA GTGGGAGACA TTGAAAGCAT GCCCTTCATT 
GAGGCCTTCC GCCAGTTCCA GTTCAAGGTC AAGAGGGAAA ACTTTTGTAA TATCCATGTC 
AGTCTGGTTC CTCAGCCAAG TTCAACAGGG GAACAGAAGA CAAAACCCAC CCAGAACAGT 
GTTCGGGAAC TTAGAGGACT CGGGCTTTCT CCAGACTTAG TGGTGTGCAG GTGCTCAAAT 
CCTCTTGACA CATCTGTGAA AGAGAAAATA TCAATGTTTT GCCATGTGGA ACCTGAACAA 
GTGATCTGTG TTCATGATGT TTCATCCATC TACCGGGTAC CCTTGTTGTT AGAAGAGCAA 
GGGGTTGTAG ACTACTTTCT TCGGAGACTT GACCTTCCTA TTGAGAGACA GTCACGAAAG 
ATGCTGATGA AATGGAAAGA GATGGCAGAC AGGTATGACC GCTTGCTGGA GACCTGCTCG 
ATCGCTCTTG TGGGCAAATA CACCAAATTC TCAGACTCGT ACGCCTCTGT CATTAAAGCG 
CTAGAGCACT CTGCATTGGC CATTAACCAC AAGCTGGAGA TCAAGTACAT CGATTCCACA 
GACCTGGAGC CAAGTACCCT GCAGGAAGAG CCTGTGCGCT ACCATGAGGC ATGGCAGAAG 
CTCTGCAGTG CTCATGGAGT GCTGGTTCCA GGAGGATTTG GTGTTCGGGG AACAGAAGGA 
AAAATTCAAG CAATTGCTTG GGCTCGGAAA CAGAAGAAGC CTTTTTTGGG TGTGTGCTTA 
GGAATGCAGC TAGCAGTGGT AGAATTTTCA AGAAATGTGC TGGGATGGCA AGATGCCAAT 
TCTACAGAGT TTGACCCCAA GACTAGTCAC CCTGTGGTTA TAGACATGCC AGAACATAAC 
CCTGGGCAAA TGGGTGGAAC CATGAGGCTG GGCAAGAGGA GAACCCTGTT CCAGACCAAG 
AACTCAGTCA TGAGGAAACT CTATGGAGAC ACAGACTACT TGGAAGAAAG GCACCGCCAC 
CGATTTGAGG TGAACCCAGT CCTGAAAAAG TGCTTGGAAG AGCAAGGCTT GAAGTTCGTT 
GGCCAAGATG TGGAAGGCGA GAGGATGGAG ATCGTGGAGT TGGAAGATCA TCCATTTTTT 
GTTGGAGTGC AGTATCACCC CGAGTTCCTG TCCAGGCCTA TCAAGCCCTC CCCACCCTAC 
TTTGGCCTCC TCCTGGCCTC TGTGGGGCGG CTCCCACATT ACCTTCAGAA AGGTTGCCGG 
CTCTCACCCA GGGACACTTA CAGTGACAGA AGCGGGAGCA GCTCCCCCGA CTCGGAAATC 
ACTGAACTCA AGTTTCCATC AATAAGTCAG GACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

CTP synthase 1, a smooth muscle-sensitive therapeutic target for effective vascular repair.
Arteriosclerosis, thrombosis, and vascular biology33(10)2336-44(2013 Oct)
Tang R,Cui XB,Wang JN,Chen SY


book

Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.
The Journal of biological chemistry287(36)30444-54(2012 Aug)
Balzarini J,Gago F,Kulik W,van Kuilenburg AB,Karlsson A,Peterson MA,Robins MJ


book

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE