Gene Symbol | Ctps |
Entrez Gene ID | 51797 |
Full Name | cytidine 5'-triphosphate synthase |
Synonyms | Ctps1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ctps cDNA ORF clone
Gene Symbol | Ctps |
Entrez Gene ID | 51797 |
Full Name | cytidine 5'-triphosphate synthase |
Synonyms | Ctps1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006503225.3 | XP_006503288.1 | CTP synthase 1 isoform X1 |
NM_001355491.1 | NP_001342420.1 | CTP synthase 1 |
NM_016748.2 | NP_058028.2 | CTP synthase 1 |
Homo sapiens (human) | CTPS1 | NP_001896.2 |
Mus musculus (house mouse) | Ctps | NP_058028.2 |
Rattus norvegicus (Norway rat) | Ctps1 | NP_001128345.1 |
Arabidopsis thaliana (thale cress) | emb2742 | NP_187873.1 |
Danio rerio (zebrafish) | ctps1a | NP_954681.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009624 | XP_318656.4 |
Oryza sativa (rice) | Os01g0654100 | NP_001043745.1 |
Xenopus tropicalis (tropical clawed frog) | ctps1 | XP_002939402.2 |
Pan troglodytes (chimpanzee) | CTPS | XP_524681.2 |
CTPS | XP_001084608.2 | |
Drosophila melanogaster (fruit fly) | CTPsyn | NP_730023.1 |
Oryza sativa (rice) | Os05g0573300 | NP_001056382.1 |
Canis lupus familiaris (dog) | CTPS | XP_005628921.1 |
Saccharomyces cerevisiae (baker's yeast) | URA8 | NP_012637.4 |
Bos taurus (cattle) | CTPS | NP_001071326.1 |
Gallus gallus (chicken) | CTPS | XP_004947749.1 |
Danio rerio (zebrafish) | ctps1b | NP_001104717.1 |
Danio rerio (zebrafish) | LOC100535094 | XP_003200276.1 |
Caenorhabditis elegans (roundworm) | ctps-1 | NP_507243.2 |
CTP synthase 1, a smooth muscle-sensitive therapeutic target for effective vascular repair.
Tang R, Cui XB, Wang JN, Chen SY
Arteriosclerosis, thrombosis, and vascular biology33(10)2336-44(2013 Oct)
Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.
Balzarini J, Gago F, Kulik W, van Kuilenburg AB, Karlsson A, Peterson MA, Robins MJ
The Journal of biological chemistry287(36)30444-54(2012 Aug)
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
CTPS1 inhibition selectively blocks smooth muscle cell proliferation without disturbing or even promoting re-endothelialization for effective vascular repair after injury.
Title: CTP synthase 1, a smooth muscle-sensitive therapeutic target for effective vascular repair.
Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.
Title: Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.
The following Ctps gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ctps cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu21440 | |
Clone ID Related Accession (Same CDS sequence) | XM_006503225.3 , NM_001355491.1 , NM_016748.2 | |
Accession Version | NM_001355491.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Mus musculus(house mouse) | |
Product | CTP synthase 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL611924.14, AK148259.1, AK161110.1 and CD363725.1. On Sep 18, 2017 this sequence version replaced XM_006503225.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.134806.1, SRR1660817.160314.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001342420.1 |
CDS | 397..2172 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001355491.1 |
1 | ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21440 | |
Clone ID Related Accession (Same CDS sequence) | XM_006503225.3 , NM_001355491.1 , NM_016748.2 | |
Accession Version | NM_016748.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | CTP synthase 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK146476.1, AK148259.1, AK161110.1 and CD363725.1. On Apr 4, 2008 this sequence version replaced NM_016748.1. Transcript Variant: This variant represents the shorter transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC006698.1, AK146476.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_058028.2 |
CDS | 139..1914 |
Translation |
Target ORF information:
Target ORF information:
|
NM_016748.2 |
1 | ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21440 | |
Clone ID Related Accession (Same CDS sequence) | XM_006503225.3 , NM_001355491.1 , NM_016748.2 | |
Accession Version | XM_006503225.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(House mouse) | |
Product | CTP synthase 1 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006503225.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006503288.1 |
CDS | 668..2443 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006503225.3 |
1 | ATGAAGTACA TTCTAGTTAC TGGTGGTGTT ATATCAGGAA TTGGAAAAGG AGTCATCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CTP synthase 1, a smooth muscle-sensitive therapeutic target for effective vascular repair. |
Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway. |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |