Gene Symbol | Ccnc |
Entrez Gene ID | 51813 |
Full Name | cyclin C |
Synonyms | AI451004,AU020987,CG1C |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ccnc cDNA ORF clone
gRNAs
Gene Symbol | Ccnc |
Entrez Gene ID | 51813 |
Full Name | cyclin C |
Synonyms | AI451004,AU020987,CG1C |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001122982.2 | NP_001116454.1 | cyclin-C isoform 2 |
NM_016746.4 | NP_058026.2 | cyclin-C isoform 1 |
NM_001290420.1 | NP_001277349.1 | cyclin-C isoform 3 |
NM_001290422.1 | NP_001277351.1 | cyclin-C isoform 2 |
Rattus norvegicus (Norway rat) | Ccnc | NP_001093942.1 |
Anopheles gambiae (African malaria mosquito) | CCNC_ANOGA | XP_313156.2 |
Arabidopsis thaliana (thale cress) | AT5G48630 | NP_199674.1 |
Arabidopsis thaliana (thale cress) | AT5G48640 | NP_199675.2 |
Homo sapiens (human) | CCNC | NP_005181.2 |
Pan troglodytes (chimpanzee) | CCNC | XP_001140770.1 |
Gallus gallus (chicken) | CCNC | NP_001161237.1 |
Danio rerio (zebrafish) | ccnc | NP_956245.1 |
Oryza sativa (rice) | Os09g0504400 | NP_001175929.1 |
Xenopus tropicalis (tropical clawed frog) | ccnc | NP_989157.2 |
Mus musculus (house mouse) | Ccnc | NP_058026.2 |
Drosophila melanogaster (fruit fly) | CycC | NP_476848.1 |
Canis lupus familiaris (dog) | CCNC | XP_005627836.1 |
Bos taurus (cattle) | CCNC | NP_001029530.1 |
Caenorhabditis elegans (roundworm) | cic-1 | NP_497548.2 |
Essential roles of G9a in cell proliferation and differentiation during tooth development.
Kamiunten T, Ideno H, Shimada A, Arai Y, Terashima T, Tomooka Y, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A
Experimental cell research357(2)202-210(2017 08)
Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein ?.
Song Z, Xiaoli AM, Zhang Q, Zhang Y, Yang EST, Wang S, Chang R, Zhang ZD, Yang G, Strich R, Pessin JE, Yang F
The Journal of biological chemistry292(21)8918-8932(2017 05)
MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.
Aranda-Orgilles B, Salda?a-Meyer R, Wang E, Trompouki E, Fassl A, Lau S, Mullenders J, Rocha PP, Raviram R, Guillamot M, S?nchez-D?az M, Wang K, Kayembe C, Zhang N, Amoasii L, Choudhuri A, Skok JA, Schober M, Reinberg D, Sicinski P, Schrewe H, Tsirigos A, Zon LI, Aifantis I
Cell stem cell19(6)784-799(2016 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
these data indicate that CycC activates adipogenesis in part by stimulating the transcriptional activity of C/EBPalpha.
Title: Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein ?.
cyclin C connects stress-induced mitochondrial hyperfission and programmed cell death in mammalian cells.
Title: Cyclin C mediates stress-induced mitochondrial fission and apoptosis.
our results suggest that mTORC1 activation in NAFLD and insulin resistance results in down-regulation of the CDK8-CycC complex and elevation of lipogenic protein expression.
Title: mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC).
cyclin-C-CDK complexes phosphorylate the Notch1 intracellular domain (ICN1) and promote ICN1 degradation
Title: Cyclin C is a haploinsufficient tumour suppressor.
Data show that the isolated 3.6-KB promoter fragment alone is not sufficient for the complete physiological modulation of cyclin C RNA.
Title: 3.6-KB mouse cyclin C promoter fragment is predominantly active in the testis.
The following Ccnc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccnc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu13805 | |
Clone ID Related Accession (Same CDS sequence) | NM_001122982.2 , NM_001290422.1 | |
Accession Version | NM_001122982.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-11 | |
Organism | Mus musculus(house mouse) | |
Product | cyclin-C isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK037957.1, AK135472.1, AK009615.1, AK153035.1 and BQ175960.1. On Mar 12, 2014 this sequence version replaced NM_001122982.1. Transcript Variant: This variant (2) has an alternate 3' exon, compared to variant 1. Variants 2 and 4 encode the same isoform (2), which is shorter by an amino acid and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087544.1, AK009615.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCAGGGA ACTTCTGGCA GAGCTCCCAC TATTTGCAGT GGATTTTGGA TAAACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001116454.1 |
CDS | 184..1032 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCAGGGA ACTTCTGGCA GAGCTCCCAC TATTTGCAGT GGATTTTGGA TAAACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu13805 | |
Clone ID Related Accession (Same CDS sequence) | NM_001122982.2 , NM_001290422.1 | |
Accession Version | NM_001290422.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-11 | |
Organism | Mus musculus(house mouse) | |
Product | cyclin-C isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK037957.1, BC120649.1 and AL772187.6. On Mar 12, 2014 this sequence version replaced XM_006538080.1. Transcript Variant: This variant (4) contains an alternate exon in the 3' coding region, compared to variant 1. Variants 2 and 4 encode the same isoform (2), which is shorter by an amino acid and has a distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK037957.1, SRR1660825.125584.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCAGGGA ACTTCTGGCA GAGCTCCCAC TATTTGCAGT GGATTTTGGA TAAACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001277351.1 |
CDS | 184..1032 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCAGGGA ACTTCTGGCA GAGCTCCCAC TATTTGCAGT GGATTTTGGA TAAACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu16892 | |
Clone ID Related Accession (Same CDS sequence) | NM_001290420.1 | |
Accession Version | NM_001290420.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 801bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-11 | |
Organism | Mus musculus(house mouse) | |
Product | cyclin-C isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK037957.1, AK135472.1 and BE653196.1. On Mar 13, 2014 this sequence version replaced XM_006538082.1. Transcript Variant: This variant (3) differs in the 3' terminal exon, compared to variant 1. It encodes isoform 3, which has a shorter C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK135472.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849385 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCAGGGA ACTTCTGGCA GAGCTCCCAC TATTTGCAGT GGATTTTGGA TAAACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001277349.1 |
CDS | 184..984 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGGGA ACTTCTGGCA GAGCTCCCAC TATTTGCAGT GGATTTTGGA TAAACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu13807 | |
Clone ID Related Accession (Same CDS sequence) | NM_016746.4 | |
Accession Version | NM_016746.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-11 | |
Organism | Mus musculus(house mouse) | |
Product | cyclin-C isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK037957.1, BC120649.1 and AL772187.6. On Mar 12, 2014 this sequence version replaced NM_016746.3. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC100396.1, U62638.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCAGGGA ACTTCTGGCA GAGCTCCCAC TATTTGCAGT GGATTTTGGA TAAACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_058026.2 |
CDS | 184..1035 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGGGA ACTTCTGGCA GAGCTCCCAC TATTTGCAGT GGATTTTGGA TAAACAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Essential roles of G9a in cell proliferation and differentiation during tooth development. |
Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein ?. |
MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. |