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Abcb10 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Abcb10
Entrez Gene ID 56199
Full Name ATP-binding cassette, sub-family B (MDR/TAP), member 10
Synonyms Abc-me,Abcb12
General protein information
Preferred Names

ATP-binding cassette, sub-family B (MDR/TAP), member 10

Names

ATP-binding cassette sub-family B member 10, mitochondrial
ABC-mitochondrial erythroid protein
ATP-binding cassette transporter 10
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

8

8|8 E2
Summary This gene encodes a member of the ATP-binding cassette superfamily of transporters. ATP-binding cassette proteins transport various molecules across extra- and intra-cellular membranes. The encoded protein is localized to the mitochondrial inner membrane where it interacts with and stabilizes mitoferrin-1, and is important for heme biosynthesis. Additional evidence suggests the encoded protein is involved in oxidative stress protection and erythropoisesis. [provided by RefSeq, May 2013].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006531201.3 XP_006531264.1 ATP-binding cassette sub-family B member 10, mitochondrial isoform X1
NM_019552.2 NP_062425.1 ATP-binding cassette sub-family B member 10, mitochondrial precursor
XM_006531201.4 XP_006531264.1 ATP-binding cassette sub-family B member 10, mitochondrial isoform X1

Pathways from BioSystems


Homologies


Homo sapiens (human) ABCB10 NP_036221.2
Bos taurus (cattle) ABCB10 XP_002698814.2
Rattus norvegicus (Norway rat) Abcb10 NP_001012166.1
Caenorhabditis elegans (roundworm) haf-3 NP_506927.2
Eremothecium gossypii AGOS_ACR022W NP_983425.2
Neurospora crassa NCU04117 XP_961273.2
Canis lupus familiaris (dog) ABCB10 XP_005618913.1
Kluyveromyces lactis KLLA0D00748g XP_453105.1
Schizosaccharomyces pombe (fission yeast) mdl1 NP_595751.1
Arabidopsis thaliana (thale cress) TAP2 NP_198720.2
Mus musculus (house mouse) Abcb10 NP_062425.1
Gallus gallus (chicken) ABCB10 XP_419578.3
Anopheles gambiae (African malaria mosquito) AgaP_AGAP002717 XP_312209.4
Caenorhabditis elegans (roundworm) haf-1 NP_503098.2
Saccharomyces cerevisiae (baker's yeast) MDL2 NP_015053.2
Pan troglodytes (chimpanzee) ABCB10 XP_003308870.1
ABCB10 XP_001082734.1
Danio rerio (zebrafish) abcb10 XP_001343218.3
Drosophila melanogaster (fruit fly) CG3156 NP_569844.2
Magnaporthe oryzae (rice blast fungus) MGG_06878 XP_003709605.1
Oryza sativa (rice) Os03g0755100 NP_001051311.1

Gene Ontology


Bibliography

Related articles in PubMed

Blood-brain barrier disruption in diabetic mice is linked to Nrf2 signaling deficits: Role of ABCB10?
Sajja RK, Prasad S, Tang S, Kaisar MA, Cucullo L
Neuroscience letters653152-158(2017 Jul)

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.
Pan J, Mor G, Ju W, Zhong J, Luo X, Aldo PB, Zhong M, Yu Y, Jenkins EC, Brown WT, Zhong N
American journal of reproductive immunology (New York, N.Y. : 1989)74(3)237-57(2015 Sep)

ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione.
Qiu W, Liesa M, Carpenter EP, Shirihai OS
PloS one10(6)e0129772(2015)

Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.
Yamamoto M, Arimura H, Fukushige T, Minami K, Nishizawa Y, Tanimoto A, Kanekura T, Nakagawa M, Akiyama S, Furukawa T
Molecular and cellular biology34(6)1077-84(2014 Mar)

Snx3 regulates recycling of the transferrin receptor and iron assimilation.
Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, Freedman ML, Kingsley PD, Palis J, Hattangadi SM, Lodish HF, Ward DM, Kaplan J, Maeda T, Ponka P, Paw BH
Cell metabolism17(3)343-52(2013 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ATP binding and hydrolysis properties of ABCB10 by using the 8-azido-ATP photolabeling technique, was characterized.
Title: ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione.

A critical role for Abcb10 in heme biosynthesis.
Title: Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.

ABC-me deletion causes an increase in mitochondrial superoxide production and protein carbonylation in erythroid precursors.
Title: The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo.

Ferrochelatase forms an oligomeric complex with Mfrn1 and Abcb10 to synergistically integrate mitochondrial iron importation and use for heme biosynthesis.
Title: Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis.

Data show that the binding domain of Mfrn1-Abcb10 interaction maps to the N terminus of Mfrn1.
Title: Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria.

The following Abcb10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcb10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu41620 XM_006531201.4
Latest version!		 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OMu18731 NM_019552.2
Latest version!		 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $391.30
$559.00
View Old Accession Versions >>
OMu41620 XM_006531201.3 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $223.30
$319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu41620
Clone ID Related Accession (Same CDS sequence) XM_006531201.3 , XM_006531201.4
Accession Version XM_006531201.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1143bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product ATP-binding cassette sub-family B member 10, mitochondrial isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006531201.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
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361
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481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGACGGAAG TGGAGAAGTA CACCGGCCGA GTGGACCAGT TGCTGCAGCT GGCACAGAAG 
GAGGCCTTGG CACGAGCCGG CTTCTTTGGA GCAGCTGGGC TCTCAGGAAA CCTGATTGTG 
CTGTCTGTCC TGTACAAAGG AGGCCTGCTG ATGGGCAGTG CCCATATGAC AGTGGGCGAG 
CTCTCTTCCT TCCTCATGTA CGCTTTCTGG GTTGGATTGA GCATCGGAGG ACTGAGTTCA 
TTCTACTCCG AGCTGATGAA AGGCCTGGGT GCTGGTGGGC GGCTCTGGGA GCTGCTGGAG 
AGACAGCCAC GGCTGCCTTT TAACGAGGGG ATGGTGTTAG ATGAGAAAAC CTTCCAGGGT 
GCCCTGGAGT TCAGAAACGT GCACTTCACA TACCCTGCTC GCCCAGAGGT GTCCGTATTC 
CAGGATTTCA GTCTTTCCAT CCCATCTGGA TCTGTCACAG CGCTGGTTGG CCCAAGTGGT 
TCTGGGAAAT CAACAGTGGT TTCGCTCCTG CTGCGGTTGT ACGACCCTAA TTCTGGAACA 
GTCAGCCTTG ATGGCCATGA CATTCGTCAG CTAAACCCCG TCTGGCTGAG ATCCAAGATT 
GGGACAGTGA GTCAGGAGCC AGTCCTGTTC TCCTGCTCTG TCGCTGAGAA CATTGCCTAT 
GGAGCTGACA ACCTCTCCTC GGTCACAGCC CAGCAGGTGG AGAGGGCCGC AGAGGTGGCC 
AACGCCGCTG AGTTCATCCG AAGCTTCCCA CAGGGCTTCG ACACTGTGGT CGGGGAGAAG 
GGCATCCTCC TGTCAGGTGG GCAGAAGCAG AGGATTGCAA TAGCCAGAGC CCTGCTGAAG 
AACCCCAAAA TTCTTCTCCT TGATGAAGCA ACCAGTGCAC TGGATGCCGA AAATGAGCAC 
CTGGTCCAGG AGGCCCTTGA CCGGCTGATG GAAGGGAGAA CCGTGCTGAT CATAGCCCAC 
CGCCTGTCCA CCATTAAGAA TGCCAACTTT GTTGCTGTCC TTGACCACGG AAAGATCTGT 
GAACACGGGA CACATGAAGA GCTGCTCCTG AAGCCCAATG GGCTTTACAG AAAACTGATG 
AACAAGCAGA GTTTCCTGTC ATATAATGGA GCAGAGCAGT TCCTGGAACC TGCACGGGCG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006531264.1
CDS367..1509
Translation

Target ORF information:

RefSeq Version XM_006531201.3
Organism Mus musculus(house mouse)
Definition Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006531201.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGACGGAAG TGGAGAAGTA CACCGGCCGA GTGGACCAGT TGCTGCAGCT GGCACAGAAG 
GAGGCCTTGG CACGAGCCGG CTTCTTTGGA GCAGCTGGGC TCTCAGGAAA CCTGATTGTG 
CTGTCTGTCC TGTACAAAGG AGGCCTGCTG ATGGGCAGTG CCCATATGAC AGTGGGCGAG 
CTCTCTTCCT TCCTCATGTA CGCTTTCTGG GTTGGATTGA GCATCGGAGG ACTGAGTTCA 
TTCTACTCCG AGCTGATGAA AGGCCTGGGT GCTGGTGGGC GGCTCTGGGA GCTGCTGGAG 
AGACAGCCAC GGCTGCCTTT TAACGAGGGG ATGGTGTTAG ATGAGAAAAC CTTCCAGGGT 
GCCCTGGAGT TCAGAAACGT GCACTTCACA TACCCTGCTC GCCCAGAGGT GTCCGTATTC 
CAGGATTTCA GTCTTTCCAT CCCATCTGGA TCTGTCACAG CGCTGGTTGG CCCAAGTGGT 
TCTGGGAAAT CAACAGTGGT TTCGCTCCTG CTGCGGTTGT ACGACCCTAA TTCTGGAACA 
GTCAGCCTTG ATGGCCATGA CATTCGTCAG CTAAACCCCG TCTGGCTGAG ATCCAAGATT 
GGGACAGTGA GTCAGGAGCC AGTCCTGTTC TCCTGCTCTG TCGCTGAGAA CATTGCCTAT 
GGAGCTGACA ACCTCTCCTC GGTCACAGCC CAGCAGGTGG AGAGGGCCGC AGAGGTGGCC 
AACGCCGCTG AGTTCATCCG AAGCTTCCCA CAGGGCTTCG ACACTGTGGT CGGGGAGAAG 
GGCATCCTCC TGTCAGGTGG GCAGAAGCAG AGGATTGCAA TAGCCAGAGC CCTGCTGAAG 
AACCCCAAAA TTCTTCTCCT TGATGAAGCA ACCAGTGCAC TGGATGCCGA AAATGAGCAC 
CTGGTCCAGG AGGCCCTTGA CCGGCTGATG GAAGGGAGAA CCGTGCTGAT CATAGCCCAC 
CGCCTGTCCA CCATTAAGAA TGCCAACTTT GTTGCTGTCC TTGACCACGG AAAGATCTGT 
GAACACGGGA CACATGAAGA GCTGCTCCTG AAGCCCAATG GGCTTTACAG AAAACTGATG 
AACAAGCAGA GTTTCCTGTC ATATAATGGA GCAGAGCAGT TCCTGGAACC TGCACGGGCG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu41620
Clone ID Related Accession (Same CDS sequence) XM_006531201.3 , XM_006531201.4
Accession Version XM_006531201.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1143bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product ATP-binding cassette sub-family B member 10, mitochondrial isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006531201.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGACGGAAG TGGAGAAGTA CACCGGCCGA GTGGACCAGT TGCTGCAGCT GGCACAGAAG 
GAGGCCTTGG CACGAGCCGG CTTCTTTGGA GCAGCTGGGC TCTCAGGAAA CCTGATTGTG 
CTGTCTGTCC TGTACAAAGG AGGCCTGCTG ATGGGCAGTG CCCATATGAC AGTGGGCGAG 
CTCTCTTCCT TCCTCATGTA CGCTTTCTGG GTTGGATTGA GCATCGGAGG ACTGAGTTCA 
TTCTACTCCG AGCTGATGAA AGGCCTGGGT GCTGGTGGGC GGCTCTGGGA GCTGCTGGAG 
AGACAGCCAC GGCTGCCTTT TAACGAGGGG ATGGTGTTAG ATGAGAAAAC CTTCCAGGGT 
GCCCTGGAGT TCAGAAACGT GCACTTCACA TACCCTGCTC GCCCAGAGGT GTCCGTATTC 
CAGGATTTCA GTCTTTCCAT CCCATCTGGA TCTGTCACAG CGCTGGTTGG CCCAAGTGGT 
TCTGGGAAAT CAACAGTGGT TTCGCTCCTG CTGCGGTTGT ACGACCCTAA TTCTGGAACA 
GTCAGCCTTG ATGGCCATGA CATTCGTCAG CTAAACCCCG TCTGGCTGAG ATCCAAGATT 
GGGACAGTGA GTCAGGAGCC AGTCCTGTTC TCCTGCTCTG TCGCTGAGAA CATTGCCTAT 
GGAGCTGACA ACCTCTCCTC GGTCACAGCC CAGCAGGTGG AGAGGGCCGC AGAGGTGGCC 
AACGCCGCTG AGTTCATCCG AAGCTTCCCA CAGGGCTTCG ACACTGTGGT CGGGGAGAAG 
GGCATCCTCC TGTCAGGTGG GCAGAAGCAG AGGATTGCAA TAGCCAGAGC CCTGCTGAAG 
AACCCCAAAA TTCTTCTCCT TGATGAAGCA ACCAGTGCAC TGGATGCCGA AAATGAGCAC 
CTGGTCCAGG AGGCCCTTGA CCGGCTGATG GAAGGGAGAA CCGTGCTGAT CATAGCCCAC 
CGCCTGTCCA CCATTAAGAA TGCCAACTTT GTTGCTGTCC TTGACCACGG AAAGATCTGT 
GAACACGGGA CACATGAAGA GCTGCTCCTG AAGCCCAATG GGCTTTACAG AAAACTGATG 
AACAAGCAGA GTTTCCTGTC ATATAATGGA GCAGAGCAGT TCCTGGAACC TGCACGGGCG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006531264.1
CDS371..1513
Translation

Target ORF information:

RefSeq Version XM_006531201.4
Organism Mus musculus(house mouse)
Definition Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006531201.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGACGGAAG TGGAGAAGTA CACCGGCCGA GTGGACCAGT TGCTGCAGCT GGCACAGAAG 
GAGGCCTTGG CACGAGCCGG CTTCTTTGGA GCAGCTGGGC TCTCAGGAAA CCTGATTGTG 
CTGTCTGTCC TGTACAAAGG AGGCCTGCTG ATGGGCAGTG CCCATATGAC AGTGGGCGAG 
CTCTCTTCCT TCCTCATGTA CGCTTTCTGG GTTGGATTGA GCATCGGAGG ACTGAGTTCA 
TTCTACTCCG AGCTGATGAA AGGCCTGGGT GCTGGTGGGC GGCTCTGGGA GCTGCTGGAG 
AGACAGCCAC GGCTGCCTTT TAACGAGGGG ATGGTGTTAG ATGAGAAAAC CTTCCAGGGT 
GCCCTGGAGT TCAGAAACGT GCACTTCACA TACCCTGCTC GCCCAGAGGT GTCCGTATTC 
CAGGATTTCA GTCTTTCCAT CCCATCTGGA TCTGTCACAG CGCTGGTTGG CCCAAGTGGT 
TCTGGGAAAT CAACAGTGGT TTCGCTCCTG CTGCGGTTGT ACGACCCTAA TTCTGGAACA 
GTCAGCCTTG ATGGCCATGA CATTCGTCAG CTAAACCCCG TCTGGCTGAG ATCCAAGATT 
GGGACAGTGA GTCAGGAGCC AGTCCTGTTC TCCTGCTCTG TCGCTGAGAA CATTGCCTAT 
GGAGCTGACA ACCTCTCCTC GGTCACAGCC CAGCAGGTGG AGAGGGCCGC AGAGGTGGCC 
AACGCCGCTG AGTTCATCCG AAGCTTCCCA CAGGGCTTCG ACACTGTGGT CGGGGAGAAG 
GGCATCCTCC TGTCAGGTGG GCAGAAGCAG AGGATTGCAA TAGCCAGAGC CCTGCTGAAG 
AACCCCAAAA TTCTTCTCCT TGATGAAGCA ACCAGTGCAC TGGATGCCGA AAATGAGCAC 
CTGGTCCAGG AGGCCCTTGA CCGGCTGATG GAAGGGAGAA CCGTGCTGAT CATAGCCCAC 
CGCCTGTCCA CCATTAAGAA TGCCAACTTT GTTGCTGTCC TTGACCACGG AAAGATCTGT 
GAACACGGGA CACATGAAGA GCTGCTCCTG AAGCCCAATG GGCTTTACAG AAAACTGATG 
AACAAGCAGA GTTTCCTGTC ATATAATGGA GCAGAGCAGT TCCTGGAACC TGCACGGGCG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu18731
Clone ID Related Accession (Same CDS sequence) NM_019552.2
Accession Version NM_019552.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2148bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-16
Organism Mus musculus(house mouse)
Product ATP-binding cassette sub-family B member 10, mitochondrial precursor
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC054793.1. On or before Dec 7, 2005 this sequence version replaced XM_925245.1, XM_917783.1, XM_925251.1, XM_925254.1, NM_019552.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC054793.1, AK081782.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 15215243; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
ATGCGCGCCC CTTCTGCTAG GGCGCTACTG CTGATTCCGC GTCGGGGCCC TGCCGTGCGA 
GCGTGGGCCC CGGCCGTCTC CTCTCGGATA TGGCTGGCTT CTGAATGGAC CCCGCTCGTA 
CGCGCGTGGA CCTCTCTGAT CCACAAGCCG GGTTCGGGCC TCCGCTTTCC CGCGCCCCTA 
TCCGGGCTGC CTGGCGGCGT GGGGCAGTGG GCCACCTCCT CGGGGGCCCG CAGGTGCTGG 
GTGCTGGCAG GACCCCGCGC CGCACATCCC CTGTTCGCCA GGCTCCAGGG TGCAGCTGCC 
ACCGGTGTGC GAGACCTTGG GAACGACTCG CAGCGGCGTC CCGCGGCGAC CGGGCGCTCA 
GAAGTATGGA AGCTCCTAGG GCTGGTGCGC CCCGAGCGCG GGAGACTGTC AGCTGCAGTT 
GGGTTTCTGG CTGTGTCCAG TGTCATCACC ATGTCTGCCC CCTTCTTCCT GGGAAGGATC 
ATTGATGTCA TCTATACCAA CCCAAGCGAG GGCTATGGCG ATAGCTTGAC TCGGCTCTGT 
GCTGTGCTCA CCTGTGTGTT CCTGTGCGGC GCTGCTGCCA ACGGCATTCG TGTCTACCTC 
ATGCAGTCTT CAGGTCAGAG CATTGTGAAC AGGCTGCGCA CCTCTCTGTT CTCCTCCATT 
CTAAGGCAAG AGGTTGCTTT CTTTGACAAG ACCCGCACAG GCGAATTAAT TAACCGCCTC 
TCCTCGGATA CCGCACTCCT GGGGCGCTCC GTGACTGAGA ACCTCTCCGA TGGCCTGAGA 
GCTGGGGCCC AGGCCTCCGT TGGTGTTGGC ATGATGTTTT TTGTGTCACC AAGTCTGGCC 
ACCTTTGTTC TGAGTGTGGT ACCGCCCATC TCTGTCCTCG CTGTGATTTA TGGGCGATAT 
CTACGGAAAC TGTCCAAAGC CACACAGGAC TCCTTGGCAG AAGCCACACA GCTAGCCGAG 
GAGCGGATTG GAAACATAAG AACCATCCGA GCTTTTGGGA AGGAGATGAC GGAAGTGGAG 
AAGTACACCG GCCGAGTGGA CCAGTTGCTG CAGCTGGCAC AGAAGGAGGC CTTGGCACGA 
GCCGGCTTCT TTGGAGCAGC TGGGCTCTCA GGAAACCTGA TTGTGCTGTC TGTCCTGTAC 
AAAGGAGGCC TGCTGATGGG CAGTGCCCAT ATGACAGTGG GCGAGCTCTC TTCCTTCCTC 
ATGTACGCTT TCTGGGTTGG ATTGAGCATC GGAGGACTGA GTTCATTCTA CTCCGAGCTG 
ATGAAAGGCC TGGGTGCTGG TGGGCGGCTC TGGGAGCTGC TGGAGAGACA GCCACGGCTG 
CCTTTTAACG AGGGGATGGT GTTAGATGAG AAAACCTTCC AGGGTGCCCT GGAGTTCAGA 
AACGTGCACT TCACATACCC TGCTCGCCCA GAGGTGTCCG TATTCCAGGA TTTCAGTCTT 
TCCATCCCAT CTGGATCTGT CACAGCGCTG GTTGGCCCAA GTGGTTCTGG GAAATCAACA 
GTGGTTTCGC TCCTGCTGCG GTTGTACGAC CCTAATTCTG GAACAGTCAG CCTTGATGGC 
CATGACATTC GTCAGCTAAA CCCCGTCTGG CTGAGATCCA AGATTGGGAC AGTGAGTCAG 
GAGCCAGTCC TGTTCTCCTG CTCTGTCGCT GAGAACATTG CCTATGGAGC TGACAACCTC 
TCCTCGGTCA CAGCCCAGCA GGTGGAGAGG GCCGCAGAGG TGGCCAACGC CGCTGAGTTC 
ATCCGAAGCT TCCCACAGGG CTTCGACACT GTGGTCGGGG AGAAGGGCAT CCTCCTGTCA 
GGTGGGCAGA AGCAGAGGAT TGCAATAGCC AGAGCCCTGC TGAAGAACCC CAAAATTCTT 
CTCCTTGATG AAGCAACCAG TGCACTGGAT GCCGAAAATG AGCACCTGGT CCAGGAGGCC 
CTTGACCGGC TGATGGAAGG GAGAACCGTG CTGATCATAG CCCACCGCCT GTCCACCATT 
AAGAATGCCA ACTTTGTTGC TGTCCTTGAC CACGGAAAGA TCTGTGAACA CGGGACACAT 
GAAGAGCTGC TCCTGAAGCC CAATGGGCTT TACAGAAAAC TGATGAACAA GCAGAGTTTC 
CTGTCATATA ATGGAGCAGA GCAGTTCCTG GAACCTGCAC GGGCGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_062425.1
CDS310..2457
Translation

Target ORF information:

RefSeq Version NM_019552.2
Organism Mus musculus(house mouse)
Definition Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 10 (Abcb10), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_019552.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
ATGCGCGCCC CTTCTGCTAG GGCGCTACTG CTGATTCCGC GTCGGGGCCC TGCCGTGCGA 
GCGTGGGCCC CGGCCGTCTC CTCTCGGATA TGGCTGGCTT CTGAATGGAC CCCGCTCGTA 
CGCGCGTGGA CCTCTCTGAT CCACAAGCCG GGTTCGGGCC TCCGCTTTCC CGCGCCCCTA 
TCCGGGCTGC CTGGCGGCGT GGGGCAGTGG GCCACCTCCT CGGGGGCCCG CAGGTGCTGG 
GTGCTGGCAG GACCCCGCGC CGCACATCCC CTGTTCGCCA GGCTCCAGGG TGCAGCTGCC 
ACCGGTGTGC GAGACCTTGG GAACGACTCG CAGCGGCGTC CCGCGGCGAC CGGGCGCTCA 
GAAGTATGGA AGCTCCTAGG GCTGGTGCGC CCCGAGCGCG GGAGACTGTC AGCTGCAGTT 
GGGTTTCTGG CTGTGTCCAG TGTCATCACC ATGTCTGCCC CCTTCTTCCT GGGAAGGATC 
ATTGATGTCA TCTATACCAA CCCAAGCGAG GGCTATGGCG ATAGCTTGAC TCGGCTCTGT 
GCTGTGCTCA CCTGTGTGTT CCTGTGCGGC GCTGCTGCCA ACGGCATTCG TGTCTACCTC 
ATGCAGTCTT CAGGTCAGAG CATTGTGAAC AGGCTGCGCA CCTCTCTGTT CTCCTCCATT 
CTAAGGCAAG AGGTTGCTTT CTTTGACAAG ACCCGCACAG GCGAATTAAT TAACCGCCTC 
TCCTCGGATA CCGCACTCCT GGGGCGCTCC GTGACTGAGA ACCTCTCCGA TGGCCTGAGA 
GCTGGGGCCC AGGCCTCCGT TGGTGTTGGC ATGATGTTTT TTGTGTCACC AAGTCTGGCC 
ACCTTTGTTC TGAGTGTGGT ACCGCCCATC TCTGTCCTCG CTGTGATTTA TGGGCGATAT 
CTACGGAAAC TGTCCAAAGC CACACAGGAC TCCTTGGCAG AAGCCACACA GCTAGCCGAG 
GAGCGGATTG GAAACATAAG AACCATCCGA GCTTTTGGGA AGGAGATGAC GGAAGTGGAG 
AAGTACACCG GCCGAGTGGA CCAGTTGCTG CAGCTGGCAC AGAAGGAGGC CTTGGCACGA 
GCCGGCTTCT TTGGAGCAGC TGGGCTCTCA GGAAACCTGA TTGTGCTGTC TGTCCTGTAC 
AAAGGAGGCC TGCTGATGGG CAGTGCCCAT ATGACAGTGG GCGAGCTCTC TTCCTTCCTC 
ATGTACGCTT TCTGGGTTGG ATTGAGCATC GGAGGACTGA GTTCATTCTA CTCCGAGCTG 
ATGAAAGGCC TGGGTGCTGG TGGGCGGCTC TGGGAGCTGC TGGAGAGACA GCCACGGCTG 
CCTTTTAACG AGGGGATGGT GTTAGATGAG AAAACCTTCC AGGGTGCCCT GGAGTTCAGA 
AACGTGCACT TCACATACCC TGCTCGCCCA GAGGTGTCCG TATTCCAGGA TTTCAGTCTT 
TCCATCCCAT CTGGATCTGT CACAGCGCTG GTTGGCCCAA GTGGTTCTGG GAAATCAACA 
GTGGTTTCGC TCCTGCTGCG GTTGTACGAC CCTAATTCTG GAACAGTCAG CCTTGATGGC 
CATGACATTC GTCAGCTAAA CCCCGTCTGG CTGAGATCCA AGATTGGGAC AGTGAGTCAG 
GAGCCAGTCC TGTTCTCCTG CTCTGTCGCT GAGAACATTG CCTATGGAGC TGACAACCTC 
TCCTCGGTCA CAGCCCAGCA GGTGGAGAGG GCCGCAGAGG TGGCCAACGC CGCTGAGTTC 
ATCCGAAGCT TCCCACAGGG CTTCGACACT GTGGTCGGGG AGAAGGGCAT CCTCCTGTCA 
GGTGGGCAGA AGCAGAGGAT TGCAATAGCC AGAGCCCTGC TGAAGAACCC CAAAATTCTT 
CTCCTTGATG AAGCAACCAG TGCACTGGAT GCCGAAAATG AGCACCTGGT CCAGGAGGCC 
CTTGACCGGC TGATGGAAGG GAGAACCGTG CTGATCATAG CCCACCGCCT GTCCACCATT 
AAGAATGCCA ACTTTGTTGC TGTCCTTGAC CACGGAAAGA TCTGTGAACA CGGGACACAT 
GAAGAGCTGC TCCTGAAGCC CAATGGGCTT TACAGAAAAC TGATGAACAA GCAGAGTTTC 
CTGTCATATA ATGGAGCAGA GCAGTTCCTG GAACCTGCAC GGGCGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Blood-brain barrier disruption in diabetic mice is linked to Nrf2 signaling deficits: Role of ABCB10?
Neuroscience letters653152-158(2017 Jul)
Sajja RK,Prasad S,Tang S,Kaisar MA,Cucullo L


book

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.
American journal of reproductive immunology (New York, N.Y. : 1989)74(3)237-57(2015 Sep)
Pan J,Mor G,Ju W,Zhong J,Luo X,Aldo PB,Zhong M,Yu Y,Jenkins EC,Brown WT,Zhong N


book

ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione.
PloS one10(6)e0129772(2015)
Qiu W,Liesa M,Carpenter EP,Shirihai OS


book

Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.
Molecular and cellular biology34(6)1077-84(2014 Mar)
Yamamoto M,Arimura H,Fukushige T,Minami K,Nishizawa Y,Tanimoto A,Kanekura T,Nakagawa M,Akiyama S,Furukawa T


book

Snx3 regulates recycling of the transferrin receptor and iron assimilation.
Cell metabolism17(3)343-52(2013 Mar)
Chen C,Garcia-Santos D,Ishikawa Y,Seguin A,Li L,Fegan KH,Hildick-Smith GJ,Shah DI,Cooney JD,Chen W,King MJ,Yien YY,Schultz IJ,Anderson H,Dalton AJ,Freedman ML,Kingsley PD,Palis J,Hattangadi SM,Lodish HF,Ward DM,Kaplan J,Maeda T,Ponka P,Paw BH