Gene Symbol | Actn4 |
Entrez Gene ID | 60595 |
Full Name | actinin alpha 4 |
Synonyms | C77391 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Actn4 cDNA ORF clone
Gene Symbol | Actn4 |
Entrez Gene ID | 60595 |
Full Name | actinin alpha 4 |
Synonyms | C77391 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001360550.1 | NP_001347479.1 | alpha-actinin-4 isoform 4 |
XM_006540257.3 | XP_006540320.1 | alpha-actinin-4 isoform X2 |
XM_006540254.3 | XP_006540317.1 | alpha-actinin-4 isoform X1 |
NM_021895.2 | NP_068695.1 | alpha-actinin-4 |
NM_001360549.1 | NP_001347478.1 | alpha-actinin-4 isoform 3 |
XM_006540255.4 | XP_006540318.1 | alpha-actinin-4 isoform X1 |
NM_001360548.1 | NP_001347477.1 | alpha-actinin-4 isoform 2 |
XM_006540256.3 | XP_006540319.1 | alpha-actinin-4 isoform X3 |
XM_006540255.3 | XP_006540318.1 | alpha-actinin-4 isoform X2 |
NM_021895.3 | NP_068695.1 | alpha-actinin-4 isoform 1 |
XM_006540257.2 | XP_006540320.1 | alpha-actinin-4 isoform X4 |
ACTN4 | XP_001083825.1 | |
Danio rerio (zebrafish) | actn4 | NP_955880.1 |
Pan troglodytes (chimpanzee) | ACTN4 | XP_003954421.1 |
Rattus norvegicus (Norway rat) | Actn4 | NP_113863.2 |
Homo sapiens (human) | ACTN4 | NP_004915.2 |
Bos taurus (cattle) | ACTN4 | NP_001091521.1 |
Schizosaccharomyces pombe (fission yeast) | ain1 | NP_594295.1 |
Canis lupus familiaris (dog) | ACTN4 | XP_541640.2 |
Mus musculus (house mouse) | Actn4 | NP_068695.1 |
Gallus gallus (chicken) | ACTN4 | NP_990457.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06475 | XP_003717088.1 |
Neurospora crassa | NCU06429 | XP_957320.1 |
Xenopus tropicalis (tropical clawed frog) | actn4 | NP_001006810.1 |
Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.
Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, Hilfiker-Kleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S
Nature medicine21(6)601-9(2015 Jun)
?-Actinin 4 potentiates nuclear factor ?-light-chain-enhancer of activated B-cell (NF-?B) activity in podocytes independent of its cytoplasmic actin binding function.
Zhao X, Hsu KS, Lim JH, Bruggeman LA, Kao HY
The Journal of biological chemistry290(1)338-49(2015 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ACTN4 is a transcriptional coactivator of NF-kappaB.
Title: ?-Actinin 4 potentiates nuclear factor ?-light-chain-enhancer of activated B-cell (NF-?B) activity in podocytes independent of its cytoplasmic actin binding function.
UCHL1 upregulation in ACTN4-associated FSGS.
Title: Ubiquitin C-terminal hydrolase L1 deletion ameliorates glomerular injury in mice with ACTN4-associated focal segmental glomerulosclerosis.
sLZIP negatively regulates skeletal muscle differentiation via interaction with ACTN4.
Title: Small leucine zipper protein (sLZIP) negatively regulates skeletal muscle differentiation via interaction with ?-actinin-4.
the C-terminal tail of alpha-actinin-4 is essential for its function in cell migration and adhesion to substratum.
Title: The carboxyl tail of alpha-actinin-4 regulates its susceptibility to m-calpain and thus functions in cell migration and spreading.
anti-dsDNA Fab may enhance F-actin formation by the proprietary modification of alpha-actinin-4
Title: The antigen-binding fragment of anti-double-stranded DNA IgG enhances F-actin formation in mesangial cells by binding to alpha-actinin-4.
The following Actn4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Actn4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu38435 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540254.3 , NM_001360548.1 | |
Accession Version | NM_001360548.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2739bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-30 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC166357.3. On Feb 6, 2018 this sequence version replaced XM_006540254.3. Transcript Variant: This variant (2) lacks an alternate internal exon and contains another alternate internal exon compared to variant 1. The resulting isoform (2) has the same length as isoform 1 but differs at two amino acid positions. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.103232.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001347477.1 |
CDS | 150..2888 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001360548.1 |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu38437 | |
Clone ID Related Accession (Same CDS sequence) | NM_001360549.1 , XM_006540256.3 | |
Accession Version | NM_001360549.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2724bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-09 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC166357.3. On Feb 6, 2018 this sequence version replaced XM_006540256.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.26899.1, SRR1660817.204409.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001347478.1 |
CDS | 150..2873 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001360549.1 |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu38435 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540254.3 , NM_001360548.1 | |
Accession Version | XM_006540254.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2739bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006540254.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540317.1 |
CDS | 150..2888 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006540254.3 |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu38436 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540255.4 , XM_006540255.3 | |
Accession Version | XM_006540255.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2724bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006540255.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540318.1 |
CDS | 170..2893 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006540255.3 |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu38437 | |
Clone ID Related Accession (Same CDS sequence) | NM_001360549.1 , XM_006540256.3 | |
Accession Version | XM_006540256.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2724bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006540256.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540319.1 |
CDS | 172..2895 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006540256.3 |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu38438 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540257.3 , XM_006540257.2 | |
Accession Version | XM_006540257.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2805bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006540257.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540320.1 |
CDS | 170..2974 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006540257.2 |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu18705 | |
Clone ID Related Accession (Same CDS sequence) | NM_021895.2 , NM_021895.3 | |
Accession Version | NM_021895.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2739bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ289242.2. On Feb 19, 2002 this sequence version replaced NM_021895.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ289242.2, AK145322.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164133 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_068695.1 |
CDS | 98..2836 |
Translation |
Target ORF information:
Target ORF information:
|
NM_021895.2 |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu18705 | |
Clone ID Related Accession (Same CDS sequence) | NM_021895.2 , NM_021895.3 | |
Accession Version | NM_021895.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2739bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-09 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK145322.1 and AI845456.1. On Feb 6, 2018 this sequence version replaced NM_021895.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK145322.1, AJ289242.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164133 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_068695.1 |
CDS | 150..2888 |
Translation |
Target ORF information:
Target ORF information:
|
NM_021895.3 |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu84133 | |
Clone ID Related Accession (Same CDS sequence) | NM_001360550.1 | |
Accession Version | NM_001360550.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1950bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-09 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 isoform 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC166357.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: SRR1660821.116228.1, SRR1660821.130733.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGACTTACG TGTCCTGCTT CTACCACGCC TTCTCGGGGG CCCAGAAGGC TGAGACCGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001347479.1 |
CDS | 1010..2959 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001360550.1 |
1 | ATGACTTACG TGTCCTGCTT CTACCACGCC TTCTCGGGGG CCCAGAAGGC TGAGACCGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu38436 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540255.4 , XM_006540255.3 | |
Accession Version | XM_006540255.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2724bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006540255.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540318.1 |
CDS | 169..2892 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006540255.4 |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu38438 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540257.3 , XM_006540257.2 | |
Accession Version | XM_006540257.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2805bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | alpha-actinin-4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006540257.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540320.1 |
CDS | 169..2973 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006540257.3 |
1 | ATGGTGGACT ACCACGCAGC GAACCAGGCG TACCAGTACG GCCCGAACAG CGGCGGCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. |
?-Actinin 4 potentiates nuclear factor ?-light-chain-enhancer of activated B-cell (NF-?B) activity in podocytes independent of its cytoplasmic actin binding function. |