Gene Symbol | Ormdl3 |
Entrez Gene ID | 66612 |
Full Name | ORM1-like 3 (S. cerevisiae) |
Synonyms | 2810011N17Rik,AI315223 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ormdl3 cDNA ORF clone
Gene Symbol | Ormdl3 |
Entrez Gene ID | 66612 |
Full Name | ORM1-like 3 (S. cerevisiae) |
Synonyms | 2810011N17Rik,AI315223 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_025661.4 | NP_079937.1 | ORM1-like protein 3 |
Saccharomyces cerevisiae (baker's yeast) | ORM1 | NP_011552.1 |
Neurospora crassa | NCU11109 | XP_001728226.1 |
Pan troglodytes (chimpanzee) | ORMDL3 | XP_003315508.1 |
Canis lupus familiaris (dog) | ORMDL3 | XP_005624602.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_16259 | XP_003709887.1 |
Homo sapiens (human) | ORMDL3 | NP_644809.1 |
Rattus norvegicus (Norway rat) | Ormdl3 | NP_001041362.1 |
Eremothecium gossypii | AGOS_ACL189C | NP_983215.1 |
ORMDL3 | XP_001087628.2 | |
Mus musculus (house mouse) | Ormdl3 | NP_079937.1 |
Gallus gallus (chicken) | ORMDL3 | XP_003642856.1 |
Drosophila melanogaster (fruit fly) | ORMDL | NP_730669.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010566 | XP_558099.3 |
Kluyveromyces lactis | KLLA0B05621g | XP_451786.1 |
Bos taurus (cattle) | ORMDL3 | NP_001069835.1 |
Danio rerio (zebrafish) | ormdl3 | NP_001006087.1 |
Saccharomyces cerevisiae (baker's yeast) | ORM2 | NP_013454.1 |
Schizosaccharomyces pombe (fission yeast) | SPBC119.09c | NP_595290.1 |
ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6?-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway.
Dang J, Bian X, Ma X, Li J, Long F, Shan S, Yuan Q, Xin Q, Li Y, Gao F, Gong Y, Liu Q
Journal of immunology (Baltimore, Md. : 1950)199(5)1647-1659(2017 Sep)
ORMDL3 is associated with airway remodeling in asthma via the ERK/MMP-9 pathway.
Yu F, Sun Y, Yu J, Ding Z, Wang J, Zhang L, Zhang T, Bai Y, Wang Y
Molecular medicine reports15(5)2969-2976(2017 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ORMDL3 mediates the autophagy via the ATF 6-Beclin1 autophagy pathway, and it facilitates the survival of splenic B cells via promoting autophagy and suppressing apoptosis
Title: ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6?-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway.
Expression levels of ORMDL3, phosphorylated (p)ERK and MMP9 were significantly greater in the asthmamodel group; however, in the group pretreated with budesonide their expression was reduced.
Title: ORMDL3 is associated with airway remodeling in asthma via the ERK/MMP-9 pathway.
inhibiting ORMDL3 in airway epithelial cells plays a significant role in induction of allergen-induced increases in airway hyperresponsiveness
Title: Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate.
Mediated by GATA3 through targeting promoter region of ORMDL3.
Title: [Recombinant platanus pollen allergen 2 (rPla a2) up-regulates the expression of ORMDL3 mediated by GATA3 in NIH3T3 cells].
ORMDL3 might influence de novo sphingolipid metabolism downstream of serine palmitoyltransferase
Title: ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase.
The following Ormdl3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ormdl3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu19448 | |
Clone ID Related Accession (Same CDS sequence) | NM_025661.4 | |
Accession Version | NM_025661.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Mus musculus(house mouse) | |
Product | ORM1-like protein 3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL591125.20. On Oct 19, 2007 this sequence version replaced NM_025661.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK009621.1, AK154085.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849386 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATGTGG GCACAGCACA CAGTGAGGTG AACCCCAACA CACGGGTGAT GAACAGTCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_079937.1 |
CDS | 144..605 |
Translation |
Target ORF information:
Target ORF information:
|
NM_025661.4 |
1 | ATGAATGTGG GCACAGCACA CAGTGAGGTG AACCCCAACA CACGGGTGAT GAACAGTCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6?-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway. |
ORMDL3 is associated with airway remodeling in asthma via the ERK/MMP-9 pathway. |