Gene Symbol | Med30 |
Entrez Gene ID | 69790 |
Full Name | mediator complex subunit 30 |
Synonyms | 1810038N03Rik,2510044J04Rik,TRAP25,Thrap6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Med30 cDNA ORF clone
Gene Symbol | Med30 |
Entrez Gene ID | 69790 |
Full Name | mediator complex subunit 30 |
Synonyms | 1810038N03Rik,2510044J04Rik,TRAP25,Thrap6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_027212.2 | NP_081488.1 | mediator of RNA polymerase II transcription subunit 30 |
Canis lupus familiaris (dog) | MED30 | XP_539144.2 |
Xenopus tropicalis (tropical clawed frog) | med30 | NP_001017241.1 |
Homo sapiens (human) | MED30 | NP_542382.1 |
Gallus gallus (chicken) | MED30 | NP_001264365.1 |
Bos taurus (cattle) | MED30 | NP_001073086.1 |
Pan troglodytes (chimpanzee) | MED30 | XP_528281.2 |
Rattus norvegicus (Norway rat) | Med30 | NP_001124011.1 |
Danio rerio (zebrafish) | med30 | NP_957011.1 |
MED30 | XP_001095901.1 | |
Mus musculus (house mouse) | Med30 | NP_081488.1 |
Drosophila melanogaster (fruit fly) | MED30 | NP_612046.1 |
Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA
Developmental biology406(1)92-103(2015 Oct)
MED30 Regulates the Proliferation and Motility of Gastric Cancer Cells.
Lee YJ, Han ME, Baek SJ, Kim SY, Oh SO
PloS one10(6)e0130826(2015)
Subunit architecture and functional modular rearrangements of the transcriptional mediator complex.
Tsai KL, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, Asturias FJ
Cell157(6)1430-44(2014 Jun)
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.
Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, Evans RM, Beutler B
Proceedings of the National Academy of Sciences of the United States of America108(49)19678-82(2011 Dec)
Mediator and cohesin connect gene expression and chromatin architecture.
Kagey MH, Newman JJ, Bilodeau S, Zhan Y, Orlando DA, van Berkum NL, Ebmeier CC, Goossens J, Rahl PB, Levine SS, Taatjes DJ, Dekker J, Young RA
Nature467(7314)430-5(2010 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
MED30 was overexpressed in gastric cancer tissues and cell lines. Moreover, MED30 overexpression increased the proliferation, migration, and invasion of gastric cancer cells
Title: MED30 Regulates the Proliferation and Motility of Gastric Cancer Cells.
Data show a missense mutation in Med30 causing progressive cardiomyopathy in homozygous mice that, although viable during lactation, show precipitous lethality 2-3 wk after weaning.
Title: Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.
The following Med30 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Med30 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu03879 | |
Clone ID Related Accession (Same CDS sequence) | NM_027212.2 | |
Accession Version | NM_027212.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-19 | |
Organism | Mus musculus(house mouse) | |
Product | mediator of RNA polymerase II transcription subunit 30 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK011104.1. On Apr 5, 2007 this sequence version replaced NM_027212.1. ##Evidence-Data-START## Transcript exon combination :: AK011104.1, AK146250.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCCACCC CTCCGCTGGC GCCCACGGGC ATGGCGTCCG GGCCCTTCGG CGGCCCGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_081488.1 |
CDS | 66..602 |
Translation |
Target ORF information:
Target ORF information:
|
NM_027212.2 |
1 | ATGTCCACCC CTCCGCTGGC GCCCACGGGC ATGGCGTCCG GGCCCTTCGG CGGCCCGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Spatiotemporal regulation of GLI target genes in the mammalian limb bud. |
MED30 Regulates the Proliferation and Motility of Gastric Cancer Cells. |
Subunit architecture and functional modular rearrangements of the transcriptional mediator complex. |
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. |
Mediator and cohesin connect gene expression and chromatin architecture. |