Gene Symbol | Tiparp |
Entrez Gene ID | 99929 |
Full Name | TCDD-inducible poly(ADP-ribose) polymerase |
Synonyms | ARTD14,AW558171,PARP7 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Tiparp cDNA ORF clone
Gene Symbol | Tiparp |
Entrez Gene ID | 99929 |
Full Name | TCDD-inducible poly(ADP-ribose) polymerase |
Synonyms | ARTD14,AW558171,PARP7 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_178892.5 | NP_849223.2 | protein mono-ADP-ribosyltransferase TIPARP |
Homo sapiens (human) | TIPARP | NP_001171646.1 |
Rattus norvegicus (Norway rat) | Tiparp | XP_003749342.1 |
Pan troglodytes (chimpanzee) | TIPARP | XP_001150766.1 |
Danio rerio (zebrafish) | tiparp | NP_001038484.1 |
Xenopus tropicalis (tropical clawed frog) | tiparp | NP_001106413.1 |
TIPARP | XP_001104362.1 | |
Canis lupus familiaris (dog) | TIPARP | XP_854837.2 |
Bos taurus (cattle) | TIPARP | NP_001192977.1 |
Mus musculus (house mouse) | Tiparp | NP_849223.2 |
Gallus gallus (chicken) | TIPARP | XP_422828.1 |
Constitutive aryl hydrocarbon receptor signaling constrains type I interferon-mediated antiviral innate defense.
Yamada T, Horimoto H, Kameyama T, Hayakawa S, Yamato H, Dazai M, Takada A, Kida H, Bott D, Zhou AC, Hutin D, Watts TH, Asaka M, Matthews J, Takaoka A
Nature immunology17(6)687-94(2016 06)
Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate.
Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P
BMC biology1419(2016 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
this study shows that aryl hydrocarbon receptor upregulates expression of TIPARP, which in turn causes downregulation of the IFN type I response
Title: Constitutive aryl hydrocarbon receptor signaling constrains type I interferon-mediated antiviral innate defense.
these data identify a new mechanism of LXR regulation that involves TIPARP, ADP-ribosylation and MACROD1.
Title: TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors.
Loss of Tiparp increases sensitivity to dioxin toxicity and lethality.
Title: Loss of the Mono-ADP-ribosyltransferase, Tiparp, Increases Sensitivity to Dioxin-induced Steatohepatitis and Lethality.
Knockdown of TiPARP, but not AHRR, increased 2,3,7,8-tetrachlorodibenzo-p-dioxin - induced CYP1A1 mRNA and AHR protein levels.
Title: Aryl hydrocarbon receptor repressor and TiPARP (ARTD14) use similar, but also distinct mechanisms to repress aryl hydrocarbon receptor signaling.
The following Tiparp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tiparp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu15999 | |
Clone ID Related Accession (Same CDS sequence) | NM_178892.5 | |
Accession Version | NM_178892.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-13 | |
Organism | Mus musculus(house mouse) | |
Product | protein mono-ADP-ribosyltransferase TIPARP | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC113279.7. On May 2, 2007 this sequence version replaced NM_178892.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK028529.1, BC068173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAAGTGG AAACCACTGA ACCTGAGCCA GACTGTGTAG TACAGCCTCC TTCTCCTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_849223.2 |
CDS | 228..2201 |
Translation |
Target ORF information:
Target ORF information:
|
NM_178892.5 |
1 | ATGGAAGTGG AAACCACTGA ACCTGAGCCA GACTGTGTAG TACAGCCTCC TTCTCCTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Constitutive aryl hydrocarbon receptor signaling constrains type I interferon-mediated antiviral innate defense. |
Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. |