FAM162A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FAM162A
Entrez Gene ID	26355
Full Name	family with sequence similarity 162 member A
Synonyms	C3orf28,E2IG5,HGTD-P
General protein information	Preferred Names family with sequence similarity 162 member A Names protein FAM162A E2-induced gene 5 protein HIF-1 alpha-responsive proapoptotic molecule growth and transformation-dependent protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q21.1
Disorder MIM:	608017

mRNA and Protein(s)

mRNA	Protein	Name
NM_014367.4	NP_055182.3	protein FAM162A
NM_014367.3	NP_055182.3	protein FAM162A

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	fam162a	NP_001082812.1
Xenopus tropicalis (tropical clawed frog)	LOC100490517	XP_002943177.2
Mus musculus (house mouse)	Fam162a	NP_081618.1
Rattus norvegicus (Norway rat)	Fam162a	NP_001025074.1
Canis lupus familiaris (dog)	FAM162A	XP_535760.2
Bos taurus (cattle)	FAM162A	NP_001040057.1
Gallus gallus (chicken)	FAM162A	XP_416495.4
Pan troglodytes (chimpanzee)	FAM162A	XP_526284.3
	FAM162A	XP_001112227.1
Homo sapiens (human)	FAM162A	NP_055182.3

Gene Ontology
Bibliography

Related articles in PubMed

Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.
O'Seaghdha CM, Yang Q, Glazer NL, Leak TS, Dehghan A, Smith AV, Kao WH, Lohman K, Hwang SJ, Johnson AD, Hofman A, Uitterlinden AG, Chen YD, , Brown EM, Siscovick DS, Harris TB, Psaty BM, Coresh J, Gudnason V, Witteman JC, Liu YM, Kestenbaum BR, Fox CS, K?ttgen A
Human molecular genetics19(21)4296-303(2010 Nov)

Expression and clinicopathological significance of human growth and transformation-dependent protein (HGTD-P) in uterine cervical cancer.
Cho YE, Kim JY, Kim YJ, Kim YW, Lee S, Park JH
Histopathology57(3)479-82(2010 Sep)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

Proapoptotic role of human growth and transformation-dependent protein in the developing rat brain after hypoxia-ischemia.
Qu Y, Mao M, Zhao F, Zhang L, Mu D
Stroke40(8)2843-8(2009 Aug)

Expression and prognostic significance of human growth and transformation-dependent protein in gastric carcinoma and gastric adenoma.
Cho YE, Kim JY, Kim YW, Park JH, Lee S
Human pathology40(7)975-81(2009 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Expression and clinicopathological significance of human growth and transformation-dependent protein (HGTD-P) in uterine cervical cancer
Title: Expression and clinicopathological significance of human growth and transformation-dependent protein (HGTD-P) in uterine cervical cancer.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

HGTD-P plays a proapoptotic role in the developing rat brain following hypoxia-ischemia by activating caspase 3 and inducing the translocation of apoptosis-inducing factor (AIF) to the nucleus.
Title: Proapoptotic role of human growth and transformation-dependent protein in the developing rat brain after hypoxia-ischemia.

human growth and transformation-dependent protein expression is a common occurrence during the progression from a normal gastric mucosa to an intestinal-type carcinoma and may be associated with tumor cell proliferation activity
Title: Expression and prognostic significance of human growth and transformation-dependent protein in gastric carcinoma and gastric adenoma.

Heat shock protein 90 physically interacts with HGTD-P.
Title: Interaction of pro-apoptotic protein HGTD-P with heat shock protein 90 is required for induction of mitochondrial apoptotic cascades.

The following FAM162A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FAM162A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29267	NM_014367.4 Latest version!	Homo sapiens family with sequence similarity 162 member A (FAM162A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu29267	NM_014367.3	Homo sapiens family with sequence similarity 162 member A (FAM162A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FAM162A ( NM_014367.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055182.3 Homo sapiens family with sequence similarity 162 member A (FAM162A), mRNA.

Price & Availability↑

CloneID	OHu29267
Clone ID Related Accession (Same CDS sequence)	NM_014367.4 , NM_014367.3
Accession Version	NM_014367.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	protein FAM162A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI460077.1, AF201944.1, AF250321.1 and AC083798.14. On Nov 23, 2018 this sequence version replaced NM_014367.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.6049.1, SRR1660807.229102.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000477892.5/ ENSP00000419088.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGAGCC TCAGCGGTCT GCGCCTGGCA GCAGGAAGCT GTTTTAGGTT ATGTGAAAGA 
GATGTTTCCT CATCTCTAAG GCTTACCAGA AGCTCTGATT TGAAGAGAAT AAATGGATTT 
TGCACAAAAC CACAGGAAAG TCCCGGAGCT CCATCCCGCA CTTACAACAG AGTGCCTTTA 
CACAAACCTA CGGATTGGCA GAAAAAGATC CTCATATGGT CAGGTCGCTT CAAAAAGGAA 
GATGAAATCC CAGAGACTGT CTCGTTGGAG ATGCTTGATG CTGCAAAGAA CAAGATGCGA 
GTGAAGATCA GCTATCTAAT GATTGCCCTG ACGGTGGTAG GATGCATCTT CATGGTTATT 
GAGGGCAAGA AGGCTGCCCA AAGACACGAG ACTTTAACAA GCTTGAACTT AGAAAAGAAA 
GCTCGTCTGA AAGAGGAAGC AGCTATGAAG GCCAAAACAG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055182.3
CDS	85..549
Translation	MGSLSGLRLAAGSCFRLCERDVSSSLRLTRSSDLKRINGFCTKPQESPGAPSRTYNRVPLHKPTDWQKKILIWSGRFKKEDEIPETVSLEMLDAAKNKMRVKISYLMIALTVVGCIFMVIEGKKAAQRHETLTSLNLEKKARLKEEAAMKAKTE

Target ORF information:

RefSeq Version	NM_014367.4
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 162 member A (FAM162A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014367.4

ORF Insert Sequence:

ATGGGGAGCC TCAGCGGTCT GCGCCTGGCA GCAGGAAGCT GTTTTAGGTT ATGTGAAAGA 
GATGTTTCCT CATCTCTAAG GCTTACCAGA AGCTCTGATT TGAAGAGAAT AAATGGATTT 
TGCACAAAAC CACAGGAAAG TCCCGGAGCT CCATCCCGCA CTTACAACAG AGTGCCTTTA 
CACAAACCTA CGGATTGGCA GAAAAAGATC CTCATATGGT CAGGTCGCTT CAAAAAGGAA 
GATGAAATCC CAGAGACTGT CTCGTTGGAG ATGCTTGATG CTGCAAAGAA CAAGATGCGA 
GTGAAGATCA GCTATCTAAT GATTGCCCTG ACGGTGGTAG GATGCATCTT CATGGTTATT 
GAGGGCAAGA AGGCTGCCCA AAGACACGAG ACTTTAACAA GCTTGAACTT AGAAAAGAAA 
GCTCGTCTGA AAGAGGAAGC AGCTATGAAG GCCAAAACAG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM162A ( NM_014367.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055182.3 Homo sapiens family with sequence similarity 162 member A (FAM162A), mRNA.

Price & Availability↑

CloneID	OHu29267
Clone ID Related Accession (Same CDS sequence)	NM_014367.4 , NM_014367.3
Accession Version	NM_014367.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	protein FAM162A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI460077.1, AF201944.1 and AF250321.1. On Jun 28, 2004 this sequence version replaced NM_014367.2. ##Evidence-Data-START## Transcript exon combination :: AF191020.1, SRR1660805.145430.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAGCC TCAGCGGTCT GCGCCTGGCA GCAGGAAGCT GTTTTAGGTT ATGTGAAAGA 
GATGTTTCCT CATCTCTAAG GCTTACCAGA AGCTCTGATT TGAAGAGAAT AAATGGATTT 
TGCACAAAAC CACAGGAAAG TCCCGGAGCT CCATCCCGCA CTTACAACAG AGTGCCTTTA 
CACAAACCTA CGGATTGGCA GAAAAAGATC CTCATATGGT CAGGTCGCTT CAAAAAGGAA 
GATGAAATCC CAGAGACTGT CTCGTTGGAG ATGCTTGATG CTGCAAAGAA CAAGATGCGA 
GTGAAGATCA GCTATCTAAT GATTGCCCTG ACGGTGGTAG GATGCATCTT CATGGTTATT 
GAGGGCAAGA AGGCTGCCCA AAGACACGAG ACTTTAACAA GCTTGAACTT AGAAAAGAAA 
GCTCGTCTGA AAGAGGAAGC AGCTATGAAG GCCAAAACAG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055182.3
CDS	91..555
Translation	MGSLSGLRLAAGSCFRLCERDVSSSLRLTRSSDLKRINGFCTKPQESPGAPSRTYNRVPLHKPTDWQKKILIWSGRFKKEDEIPETVSLEMLDAAKNKMRVKISYLMIALTVVGCIFMVIEGKKAAQRHETLTSLNLEKKARLKEEAAMKAKTE

Target ORF information:

RefSeq Version	NM_014367.3
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 162 member A (FAM162A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014367.3

ORF Insert Sequence:

ATGGGGAGCC TCAGCGGTCT GCGCCTGGCA GCAGGAAGCT GTTTTAGGTT ATGTGAAAGA 
GATGTTTCCT CATCTCTAAG GCTTACCAGA AGCTCTGATT TGAAGAGAAT AAATGGATTT 
TGCACAAAAC CACAGGAAAG TCCCGGAGCT CCATCCCGCA CTTACAACAG AGTGCCTTTA 
CACAAACCTA CGGATTGGCA GAAAAAGATC CTCATATGGT CAGGTCGCTT CAAAAAGGAA 
GATGAAATCC CAGAGACTGT CTCGTTGGAG ATGCTTGATG CTGCAAAGAA CAAGATGCGA 
GTGAAGATCA GCTATCTAAT GATTGCCCTG ACGGTGGTAG GATGCATCTT CATGGTTATT 
GAGGGCAAGA AGGCTGCCCA AAGACACGAG ACTTTAACAA GCTTGAACTT AGAAAAGAAA 
GCTCGTCTGA AAGAGGAAGC AGCTATGAAG GCCAAAACAG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.
Human molecular genetics19(21)4296-303(2010 Nov)
O'Seaghdha CM,Yang Q,Glazer NL,Leak TS,Dehghan A,Smith AV,Kao WH,Lohman K,Hwang SJ,Johnson AD,Hofman A,Uitterlinden AG,Chen YD,,Brown EM,Siscovick DS,Harris TB,Psaty BM,Coresh J,Gudnason V,Witteman JC,Liu YM,Kestenbaum BR,Fox CS,K?ttgen A

Expression and clinicopathological significance of human growth and transformation-dependent protein (HGTD-P) in uterine cervical cancer.
Histopathology57(3)479-82(2010 Sep)
Cho YE,Kim JY,Kim YJ,Kim YW,Lee S,Park JH

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

Proapoptotic role of human growth and transformation-dependent protein in the developing rat brain after hypoxia-ischemia.
Stroke40(8)2843-8(2009 Aug)
Qu Y,Mao M,Zhao F,Zhang L,Mu D

Expression and prognostic significance of human growth and transformation-dependent protein in gastric carcinoma and gastric adenoma.
Human pathology40(7)975-81(2009 Jul)
Cho YE,Kim JY,Kim YW,Park JH,Lee S