Hnrnpa1 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Hnrnpa1 |
| Entrez Gene ID | 29578 |
| Full Name | heterogeneous nuclear ribonucleoprotein A1 |
| Synonyms | Hnrpa1,hnRNP A1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | involved in the packaging of pre-mRNA into heterologous nuclear ribonucleoprotein particles and in the transport of poly-A mRNA from the nucleus to the cytoplasm; may modulate splice site selection [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| XM_006242384.1 | XP_006242446.1 | heterogeneous nuclear ribonucleoprotein A1 isoform X1 |
| NM_017248.1 | NP_058944.1 | heterogeneous nuclear ribonucleoprotein A1 |
| Homo sapiens (human) | HNRNPA1 | NP_002127.1 |
| Pan troglodytes (chimpanzee) | HNRNPA1 | NP_001184040.1 |
| Pan troglodytes (chimpanzee) | LOC100615525 | XP_003318234.1 |
| HNRNPA1 | NP_001036248.1 | |
| Bos taurus (cattle) | HNRNPA1 | NP_001039376.1 |
| Gallus gallus (chicken) | LOC100859627 | XP_004942777.1 |
| Pan troglodytes (chimpanzee) | HNRPA1LK1 | NP_001091892.1 |
| Rattus norvegicus (Norway rat) | Hnrnpa1 | NP_058944.1 |
Related articles in PubMed
A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.
Treiber T, Treiber N, Plessmann U, Harlander S, Dai? JL, Eichner N, Lehmann G, Schall K, Urlaub H, Meister G
Molecular cell66(2)270-284.e13(2017 Apr)
Whole-exome sequencing identifies a missense mutation in hnRNPA1 in a family with flail arm ALS.
Liu Q, Shu S, Wang RR, Liu F, Cui B, Guo XN, Lu CX, Li XG, Liu MS, Peng B, Cui LY, Zhang X
Neurology87(17)1763-1769(2016 Oct)
Regulation of RAGE splicing by hnRNP A1 and Tra2?-1 and its potential role in AD pathogenesis.
Liu XY, Li HL, Su JB, Ding FH, Zhao JJ, Chai F, Li YX, Cui SC, Sun FY, Wu ZY, Xu P, Chen XH
Journal of neurochemistry133(2)187-98(2015 Apr)
TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres.
Porro A, Feuerhahn S, Lingner J
Cell reports6(4)765-76(2014 Feb)
Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modules.
Sangith N, Srinivasaraghavan K, Sahu I, Desai A, Medipally S, Somavarappu AK, Verma C, Venkatraman P
FEBS open bio4571-83(2014)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data indicate that heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) participates in the IRES (internal ribosome entry site) -dependent translation of sterol-regulatory-element-binding protein 1 (SREBP-1a) mRNA through RNA-protein interaction.
Title: hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress.
data show that hnRNP A1 is an important Quaking target that contributes to its control of myelin gene expression
Title: Quaking regulates Hnrnpa1 expression through its 3' UTR in oligodendrocyte precursor cells.
The following Hnrnpa1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hnrnpa1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa03389 | |
| Clone ID Related Accession (Same CDS sequence) | NM_017248.1 | |
| Accession Version | NM_017248.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 963bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | heterogeneous nuclear ribonucleoprotein A1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M12156.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M12156.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTCTAAGT CAGAGTCCCC CAAGGAACCG GAACAGCTGC GGAAGCTCTT CATTGGAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_058944.1 |
| CDS | 29..991 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_017248.1 |
ORF Insert Sequence:
1 | ATGTCTAAGT CAGAGTCCCC CAAGGAACCG GAACAGCTGC GGAAGCTCTT CATTGGAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa30761 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006242384.1 | |
| Accession Version | XM_006242384.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | heterogeneous nuclear ribonucleoprotein A1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTCTAAGT CAGAGTCCCC CAAGGAACCG GAACAGCTGC GGAAGCTCTT CATTGGAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006242446.1 |
| CDS | 367..1488 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006242384.1 |
ORF Insert Sequence:
1 | ATGTCTAAGT CAGAGTCCCC CAAGGAACCG GAACAGCTGC GGAAGCTCTT CATTGGAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis. |
|
Whole-exome sequencing identifies a missense mutation in hnRNPA1 in a family with flail arm ALS. |
|
Regulation of RAGE splicing by hnRNP A1 and Tra2?-1 and its potential role in AD pathogenesis. |
|
TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres. |
|
Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modules. |