Mcm2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Mcm2
Entrez Gene ID	312538
Full Name	minichromosome maintenance complex component 2
General protein information	Preferred Names minichromosome maintenance complex component 2 Names DNA replication licensing factor MCM2 minichromosome maintenance deficient 2 mitotin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q34

mRNA and Protein(s)

mRNA Protein Name

XM_006236863.1 XP_006236925.1 DNA replication licensing factor MCM2 isoform X1

NM_001107873.2 NP_001101343.2 DNA replication licensing factor MCM2
Pathways from BioSystems

mRNA	Protein	Name
XM_006236863.1	XP_006236925.1	DNA replication licensing factor MCM2 isoform X1
NM_001107873.2	NP_001101343.2	DNA replication licensing factor MCM2

Homologies

Pan troglodytes (chimpanzee)	MCM2	XP_516724.2
	MCM2	XP_001099580.2
Rattus norvegicus (Norway rat)	Mcm2	NP_001101343.2
Xenopus tropicalis (tropical clawed frog)	mcm2	NP_001006772.1
Canis lupus familiaris (dog)	MCM2	XP_541736.3
Gallus gallus (chicken)	MCM2	NP_001006139.1
Drosophila melanogaster (fruit fly)	Mcm2	NP_477121.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004275	XP_313198.5
Kluyveromyces lactis	KLLA0F12584g	XP_455649.1
Arabidopsis thaliana (thale cress)	MCM2	NP_175112.2
Oryza sativa (rice)	Os11g0484300	NP_001067910.1
Bos taurus (cattle)	MCM2	XP_002707828.1
Mus musculus (house mouse)	Mcm2	NP_032590.2
Caenorhabditis elegans (roundworm)	mcm-2	NP_001022416.1
Saccharomyces cerevisiae (baker's yeast)	MCM2	NP_009530.1
Eremothecium gossypii	AGOS_AFR178W	NP_985725.1
Magnaporthe oryzae (rice blast fungus)	MGG_08122	XP_003715082.1
Neurospora crassa	NCU04327	XP_960973.1
Homo sapiens (human)	MCM2	NP_004517.2
Danio rerio (zebrafish)	mcm2	NP_775364.1
Schizosaccharomyces pombe (fission yeast)	mcm2	NP_595477.1

Gene Ontology
Bibliography

Related articles in PubMed

Whole Exome Sequencing Identified MCM2 as a Novel Causative Gene for Autosomal Dominant Nonsyndromic Deafness in a Chinese Family.
Gao J, Wang Q, Dong C, Chen S, Qi Y, Liu Y
PloS one10(7)e0133522(2015)

Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons.
Huang W, She L, Chang XY, Yang RR, Wang L, Ji HB, Jiao JW, Poo MM
Proceedings of the National Academy of Sciences of the United States of America111(1)469-74(2014 Jan)

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication.
Vannier JB, Sandhu S, Petalcorin MI, Wu X, Nabi Z, Ding H, Boulton SJ
Science (New York, N.Y.)342(6155)239-42(2013 Oct)

Interactions of MCP1 with components of the replication machinery in mammalian cells.
Bronze-da-Rocha E, Lin CM, Shimura T, Aladjem MI
International journal of biological sciences7(2)193-208(2011 Feb)

Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease.
Bonda DJ, Evans TA, Santocanale C, Llos? JC, Vi?a J, Bajic V, Castellani RJ, Siedlak SL, Perry G, Smith MA, Lee HG
Aging1(4)382-8(2009 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mcm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mcm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06181	NM_001107873.2 Latest version!	Rattus norvegicus minichromosome maintenance complex component 2 (Mcm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa06181	XM_006236863.1 Latest version!	Rattus norvegicus minichromosome maintenance complex component 2 (Mcm2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mcm2 ( NM_001107873.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101343.2 Rattus norvegicus minichromosome maintenance complex component 2 (Mcm2), mRNA.

Price & Availability↑

CloneID	ORa06181
Clone ID Related Accession (Same CDS sequence)	XM_006236863.1 , NM_001107873.2
Accession Version	NM_001107873.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2718bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Rattus norvegicus(Norway rat)
Product	DNA replication licensing factor MCM2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC120997.5. On Jan 11, 2008 this sequence version replaced NM_001107873.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGAGT CTTCTGAGTC CTTCTCGGCA GCATCTAGCC CTGCCCCTCA GCGGCGACGG 
ATCAGTGATC CCCTCACTTC CAGCCCAGGC CGCAGCTCCA GACGTGCTGA CGCTCTTACC 
TCCAGCCCTG GCAGAGACCT CCCCCCATTT GAGGATGAGT CCGAGGGGCT GCTGGGCACG 
GAGGGGCCTG TGGAGGAAGA AGAGGATGGA GAGGAACTCA TTGGTGATGG CATGGAGAGA 
GACTACCGTC CCATTCCCGA GCTCGATGTC TACGAGGCAG AGGGATTGGC CCTGGATGAT 
GAAGATGTGG AGGAGCTGAC AGCCAGTCAG AGGGAGGCAG CTGAGCGGGC TATGAGGCAG 
CGGGACCGTG AGGCTGGCAG AGGCCTGGGT CGCATGCGTC GTGGGCTGCT GTATGACAGC 
GACGAAGAAG ATGAGGAGCG GCCTGCCCGT AAGCGCCGCC ACATAGAGCG TGCCACAGAG 
GATGGCGAGG AGGATGAAGA GATGATTGAG AGTATTGAGA ACCTGGAGGA CCTCAAGGGC 
CACTCGGTGC GAGAGTGGGT GAGCATGGCA GGGCCCAGAC TGGAGATCCA CCACCGTTTC 
AAGAACTTCT TGCGCACCCA CGTGGACAGC CATGGCCACA ACGTCTTCAA GGAGCGTATC 
AGTGATATGT GCAAAGAGAA CCGGGAGAGT TTGGTGGTAA ATTATGAAGA CCTGGCAGCC 
CGGGAACATG TGTTGGCATA CTTCCTACCC GAGGCACCCG CTGAGCTGCT GCAGATCTTC 
GATGAGGCTG CCCTGGAGGT TGTGCTGGCC ATGTACCCTA AATATGACCG CATCACCAAC 
CACATTCACG TGCGCATCTC CCACCTGCCT CTGGTGGAGG AGCTGCGTTC ACTGAGGCAG 
CTACACCTGA ACCAGCTCAT CCGTACCAGC GGTGTGGTGA CCAGCTGCAC TGGAGTCCTG 
CCCCAGCTCA GCATGGTCAA GTATAACTGT AGCAAGTGCA ACTTTATACT GGGGCCTTTC 
TGCCAGTCTC AGAACCAGGA GGTGAAGCCT GGTTCCTGCC CTGAGTGCCA GTCAACTGGG 
CCCTTTGAGA TCAACATGGA GGAGACCATC TATCAGAACT ACCAACGGAT CCGCATCCAG 
GAGAGTCCCG GCAAGGTGGC AGCTGGCCGG CTGCCCCGTT CCAAGGATGC CATCCTCCTT 
GCTGATCTGG TGGACAGCTG CAAGCCAGGA GACGAGATAG AGCTGACCGG CATTTACCAC 
AATAATTATG ATGGCTCACT TAACACCACC AACGGCTTTC CCGTCTTCGC CACCATCATC 
CTGGCCAACC ACGTTGCCAA GAAGGACAAC AAAGTGGCCG TGGGTGAGCT CACTGATGAG 
GACGTGAAGA TGATCACCAG TCTTTCCAAG GATCAGCAAA TCGGAGAGAA GATCTTTGCC 
AGCATTGCGC CCTCCATCTA TGGGCATGAA GACATCAAGA GAGGCCTGGC TCTGGCTCTG 
TTTGGAGGGG AGCCCAAGAA CCCAGGTGGA AAGCACAAAG TTCGAGGTGA CATCAATGTG 
CTCCTGTGTG GGGACCCTGG CACAGCGAAG TCCCAGTTCC TCAAATACAT CGAGAAAGTA 
TCTAGCCGTG CCATTTTCAC CACCGGCCAG GGTGCGTCAG CCGTGGGTCT CACAGCGTAT 
GTTCAGCGGC ATCCTGTCAG CAGAGAGTGG ACCTTAGAGG CTGGAGCCCT GGTTCTGGCC 
GACCGGGGAG TGTGTCTCAT TGATGAGTTT GACAAGATGA ATGACCAGGA CAGGACCAGC 
ATCCACGAGG CCATGGAGCA GCAAAGCATC TCCATCTCCA AGGCCGGCAT CGTTACCTCA 
CTGCAAGCCC GCTGCACCGT CATAGCTGCT GCCAACCCCA TAGGAGGCCG CTACGACCCT 
TCACTGACCT TCTCAGAGAA TGTAGACCTC ACAGAGCCCA TCATTTCCCG CTTTGATGTC 
CTGTGTGTGG TGAGGGACAC TGTTGATCCT GTTCAGGATG AGATGCTGGC CCGCTTTGTG 
GTTGGCAGCC ACGTCAGACA CCACCCCAGC AACAAGAAGG ACGAAGGGCT GACCAACGGT 
GGCACCACAG AGCCAGCCAT GCCCAACACA TACGGTGTGG AGCCCCTGCC TCAGGAGGTC 
CTGAAGAAGT ATATCATCTA TGCCAAGGAA CGGGTCCGCC CAAAGCTCAA CCAGATGGAC 
CAGGACAAAG TGGCCAGGAT GTACAGCGAC CTGAGGAAGG AGTCCATGGC AACGGGCAGT 
ATTCCCATCA CAGTGCGACA CATCGAGTCC ATGATCCGCA TGGCAGAGGC CCATGCACGC 
ATGCACCTGC GAGACTACGT GATGGAAGAT GATGTCAACA TGGCCATCCG CGTGATGCTG 
GAGAGCTTCA TTGACACCCA AAAGTTCAGT GTCATGCGCA GCATGCGCAA GACTTTTGCC 
CGGTATCTCT CCTTCCGTCG GGATAACAAT GACCTGCTGC TCTTCATACT GAAGCAGTTG 
GTGGCTGAGC AGGTGACATA CCAACGTAAC CGCTTTGGGG CCCAACAGGA CACCATCGAA 
ATACCTGAGA AGGACCTGAT GGACAAGGCC AGGCAGATCA ATATCCACAA CCTGTCCGCC 
TTCTACGACA GCGACCTCTT CAAAATCAAC AAGTTCAGCC GTGACCTGAA ACGCAAGCTG 
ATCCTACAGC AGTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101343.2
CDS	35..2752
Translation	MAESSESFSAASSPAPQRRRISDPLTSSPGRSSRRADALTSSPGRDLPPFEDESEGLLGTEGPVEEEEDGEELIGDGMERDYRPIPELDVYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRHIERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCSKCNFILGPFCQSQNQEVKPGSCPECQSTGPFEINMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTTNGFPVFATIILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKKDEGLTNGGTTEPAMPNTYGVEPLPQEVLKKYIIYAKERVRPKLNQMDQDKVARMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVMEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNDLLLFILKQLVAEQVTYQRNRFGAQQDTIEIPEKDLMDKARQINIHNLSAFYDSDLFKINKFSRDLKRKLILQQF

Target ORF information:

RefSeq Version	NM_001107873.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus minichromosome maintenance complex component 2 (Mcm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107873.2

ORF Insert Sequence:

ATGGCGGAGT CTTCTGAGTC CTTCTCGGCA GCATCTAGCC CTGCCCCTCA GCGGCGACGG 
ATCAGTGATC CCCTCACTTC CAGCCCAGGC CGCAGCTCCA GACGTGCTGA CGCTCTTACC 
TCCAGCCCTG GCAGAGACCT CCCCCCATTT GAGGATGAGT CCGAGGGGCT GCTGGGCACG 
GAGGGGCCTG TGGAGGAAGA AGAGGATGGA GAGGAACTCA TTGGTGATGG CATGGAGAGA 
GACTACCGTC CCATTCCCGA GCTCGATGTC TACGAGGCAG AGGGATTGGC CCTGGATGAT 
GAAGATGTGG AGGAGCTGAC AGCCAGTCAG AGGGAGGCAG CTGAGCGGGC TATGAGGCAG 
CGGGACCGTG AGGCTGGCAG AGGCCTGGGT CGCATGCGTC GTGGGCTGCT GTATGACAGC 
GACGAAGAAG ATGAGGAGCG GCCTGCCCGT AAGCGCCGCC ACATAGAGCG TGCCACAGAG 
GATGGCGAGG AGGATGAAGA GATGATTGAG AGTATTGAGA ACCTGGAGGA CCTCAAGGGC 
CACTCGGTGC GAGAGTGGGT GAGCATGGCA GGGCCCAGAC TGGAGATCCA CCACCGTTTC 
AAGAACTTCT TGCGCACCCA CGTGGACAGC CATGGCCACA ACGTCTTCAA GGAGCGTATC 
AGTGATATGT GCAAAGAGAA CCGGGAGAGT TTGGTGGTAA ATTATGAAGA CCTGGCAGCC 
CGGGAACATG TGTTGGCATA CTTCCTACCC GAGGCACCCG CTGAGCTGCT GCAGATCTTC 
GATGAGGCTG CCCTGGAGGT TGTGCTGGCC ATGTACCCTA AATATGACCG CATCACCAAC 
CACATTCACG TGCGCATCTC CCACCTGCCT CTGGTGGAGG AGCTGCGTTC ACTGAGGCAG 
CTACACCTGA ACCAGCTCAT CCGTACCAGC GGTGTGGTGA CCAGCTGCAC TGGAGTCCTG 
CCCCAGCTCA GCATGGTCAA GTATAACTGT AGCAAGTGCA ACTTTATACT GGGGCCTTTC 
TGCCAGTCTC AGAACCAGGA GGTGAAGCCT GGTTCCTGCC CTGAGTGCCA GTCAACTGGG 
CCCTTTGAGA TCAACATGGA GGAGACCATC TATCAGAACT ACCAACGGAT CCGCATCCAG 
GAGAGTCCCG GCAAGGTGGC AGCTGGCCGG CTGCCCCGTT CCAAGGATGC CATCCTCCTT 
GCTGATCTGG TGGACAGCTG CAAGCCAGGA GACGAGATAG AGCTGACCGG CATTTACCAC 
AATAATTATG ATGGCTCACT TAACACCACC AACGGCTTTC CCGTCTTCGC CACCATCATC 
CTGGCCAACC ACGTTGCCAA GAAGGACAAC AAAGTGGCCG TGGGTGAGCT CACTGATGAG 
GACGTGAAGA TGATCACCAG TCTTTCCAAG GATCAGCAAA TCGGAGAGAA GATCTTTGCC 
AGCATTGCGC CCTCCATCTA TGGGCATGAA GACATCAAGA GAGGCCTGGC TCTGGCTCTG 
TTTGGAGGGG AGCCCAAGAA CCCAGGTGGA AAGCACAAAG TTCGAGGTGA CATCAATGTG 
CTCCTGTGTG GGGACCCTGG CACAGCGAAG TCCCAGTTCC TCAAATACAT CGAGAAAGTA 
TCTAGCCGTG CCATTTTCAC CACCGGCCAG GGTGCGTCAG CCGTGGGTCT CACAGCGTAT 
GTTCAGCGGC ATCCTGTCAG CAGAGAGTGG ACCTTAGAGG CTGGAGCCCT GGTTCTGGCC 
GACCGGGGAG TGTGTCTCAT TGATGAGTTT GACAAGATGA ATGACCAGGA CAGGACCAGC 
ATCCACGAGG CCATGGAGCA GCAAAGCATC TCCATCTCCA AGGCCGGCAT CGTTACCTCA 
CTGCAAGCCC GCTGCACCGT CATAGCTGCT GCCAACCCCA TAGGAGGCCG CTACGACCCT 
TCACTGACCT TCTCAGAGAA TGTAGACCTC ACAGAGCCCA TCATTTCCCG CTTTGATGTC 
CTGTGTGTGG TGAGGGACAC TGTTGATCCT GTTCAGGATG AGATGCTGGC CCGCTTTGTG 
GTTGGCAGCC ACGTCAGACA CCACCCCAGC AACAAGAAGG ACGAAGGGCT GACCAACGGT 
GGCACCACAG AGCCAGCCAT GCCCAACACA TACGGTGTGG AGCCCCTGCC TCAGGAGGTC 
CTGAAGAAGT ATATCATCTA TGCCAAGGAA CGGGTCCGCC CAAAGCTCAA CCAGATGGAC 
CAGGACAAAG TGGCCAGGAT GTACAGCGAC CTGAGGAAGG AGTCCATGGC AACGGGCAGT 
ATTCCCATCA CAGTGCGACA CATCGAGTCC ATGATCCGCA TGGCAGAGGC CCATGCACGC 
ATGCACCTGC GAGACTACGT GATGGAAGAT GATGTCAACA TGGCCATCCG CGTGATGCTG 
GAGAGCTTCA TTGACACCCA AAAGTTCAGT GTCATGCGCA GCATGCGCAA GACTTTTGCC 
CGGTATCTCT CCTTCCGTCG GGATAACAAT GACCTGCTGC TCTTCATACT GAAGCAGTTG 
GTGGCTGAGC AGGTGACATA CCAACGTAAC CGCTTTGGGG CCCAACAGGA CACCATCGAA 
ATACCTGAGA AGGACCTGAT GGACAAGGCC AGGCAGATCA ATATCCACAA CCTGTCCGCC 
TTCTACGACA GCGACCTCTT CAAAATCAAC AAGTTCAGCC GTGACCTGAA ACGCAAGCTG 
ATCCTACAGC AGTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mcm2 ( XM_006236863.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236925.1 Rattus norvegicus minichromosome maintenance complex component 2 (Mcm2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa06181
Clone ID Related Accession (Same CDS sequence)	XM_006236863.1 , NM_001107873.2
Accession Version	XM_006236863.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2718bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	DNA replication licensing factor MCM2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGAGT CTTCTGAGTC CTTCTCGGCA GCATCTAGCC CTGCCCCTCA GCGGCGACGG 
ATCAGTGATC CCCTCACTTC CAGCCCAGGC CGCAGCTCCA GACGTGCTGA CGCTCTTACC 
TCCAGCCCTG GCAGAGACCT CCCCCCATTT GAGGATGAGT CCGAGGGGCT GCTGGGCACG 
GAGGGGCCTG TGGAGGAAGA AGAGGATGGA GAGGAACTCA TTGGTGATGG CATGGAGAGA 
GACTACCGTC CCATTCCCGA GCTCGATGTC TACGAGGCAG AGGGATTGGC CCTGGATGAT 
GAAGATGTGG AGGAGCTGAC AGCCAGTCAG AGGGAGGCAG CTGAGCGGGC TATGAGGCAG 
CGGGACCGTG AGGCTGGCAG AGGCCTGGGT CGCATGCGTC GTGGGCTGCT GTATGACAGC 
GACGAAGAAG ATGAGGAGCG GCCTGCCCGT AAGCGCCGCC ACATAGAGCG TGCCACAGAG 
GATGGCGAGG AGGATGAAGA GATGATTGAG AGTATTGAGA ACCTGGAGGA CCTCAAGGGC 
CACTCGGTGC GAGAGTGGGT GAGCATGGCA GGGCCCAGAC TGGAGATCCA CCACCGTTTC 
AAGAACTTCT TGCGCACCCA CGTGGACAGC CATGGCCACA ACGTCTTCAA GGAGCGTATC 
AGTGATATGT GCAAAGAGAA CCGGGAGAGT TTGGTGGTAA ATTATGAAGA CCTGGCAGCC 
CGGGAACATG TGTTGGCATA CTTCCTACCC GAGGCACCCG CTGAGCTGCT GCAGATCTTC 
GATGAGGCTG CCCTGGAGGT TGTGCTGGCC ATGTACCCTA AATATGACCG CATCACCAAC 
CACATTCACG TGCGCATCTC CCACCTGCCT CTGGTGGAGG AGCTGCGTTC ACTGAGGCAG 
CTACACCTGA ACCAGCTCAT CCGTACCAGC GGTGTGGTGA CCAGCTGCAC TGGAGTCCTG 
CCCCAGCTCA GCATGGTCAA GTATAACTGT AGCAAGTGCA ACTTTATACT GGGGCCTTTC 
TGCCAGTCTC AGAACCAGGA GGTGAAGCCT GGTTCCTGCC CTGAGTGCCA GTCAACTGGG 
CCCTTTGAGA TCAACATGGA GGAGACCATC TATCAGAACT ACCAACGGAT CCGCATCCAG 
GAGAGTCCCG GCAAGGTGGC AGCTGGCCGG CTGCCCCGTT CCAAGGATGC CATCCTCCTT 
GCTGATCTGG TGGACAGCTG CAAGCCAGGA GACGAGATAG AGCTGACCGG CATTTACCAC 
AATAATTATG ATGGCTCACT TAACACCACC AACGGCTTTC CCGTCTTCGC CACCATCATC 
CTGGCCAACC ACGTTGCCAA GAAGGACAAC AAAGTGGCCG TGGGTGAGCT CACTGATGAG 
GACGTGAAGA TGATCACCAG TCTTTCCAAG GATCAGCAAA TCGGAGAGAA GATCTTTGCC 
AGCATTGCGC CCTCCATCTA TGGGCATGAA GACATCAAGA GAGGCCTGGC TCTGGCTCTG 
TTTGGAGGGG AGCCCAAGAA CCCAGGTGGA AAGCACAAAG TTCGAGGTGA CATCAATGTG 
CTCCTGTGTG GGGACCCTGG CACAGCGAAG TCCCAGTTCC TCAAATACAT CGAGAAAGTA 
TCTAGCCGTG CCATTTTCAC CACCGGCCAG GGTGCGTCAG CCGTGGGTCT CACAGCGTAT 
GTTCAGCGGC ATCCTGTCAG CAGAGAGTGG ACCTTAGAGG CTGGAGCCCT GGTTCTGGCC 
GACCGGGGAG TGTGTCTCAT TGATGAGTTT GACAAGATGA ATGACCAGGA CAGGACCAGC 
ATCCACGAGG CCATGGAGCA GCAAAGCATC TCCATCTCCA AGGCCGGCAT CGTTACCTCA 
CTGCAAGCCC GCTGCACCGT CATAGCTGCT GCCAACCCCA TAGGAGGCCG CTACGACCCT 
TCACTGACCT TCTCAGAGAA TGTAGACCTC ACAGAGCCCA TCATTTCCCG CTTTGATGTC 
CTGTGTGTGG TGAGGGACAC TGTTGATCCT GTTCAGGATG AGATGCTGGC CCGCTTTGTG 
GTTGGCAGCC ACGTCAGACA CCACCCCAGC AACAAGAAGG ACGAAGGGCT GACCAACGGT 
GGCACCACAG AGCCAGCCAT GCCCAACACA TACGGTGTGG AGCCCCTGCC TCAGGAGGTC 
CTGAAGAAGT ATATCATCTA TGCCAAGGAA CGGGTCCGCC CAAAGCTCAA CCAGATGGAC 
CAGGACAAAG TGGCCAGGAT GTACAGCGAC CTGAGGAAGG AGTCCATGGC AACGGGCAGT 
ATTCCCATCA CAGTGCGACA CATCGAGTCC ATGATCCGCA TGGCAGAGGC CCATGCACGC 
ATGCACCTGC GAGACTACGT GATGGAAGAT GATGTCAACA TGGCCATCCG CGTGATGCTG 
GAGAGCTTCA TTGACACCCA AAAGTTCAGT GTCATGCGCA GCATGCGCAA GACTTTTGCC 
CGGTATCTCT CCTTCCGTCG GGATAACAAT GACCTGCTGC TCTTCATACT GAAGCAGTTG 
GTGGCTGAGC AGGTGACATA CCAACGTAAC CGCTTTGGGG CCCAACAGGA CACCATCGAA 
ATACCTGAGA AGGACCTGAT GGACAAGGCC AGGCAGATCA ATATCCACAA CCTGTCCGCC 
TTCTACGACA GCGACCTCTT CAAAATCAAC AAGTTCAGCC GTGACCTGAA ACGCAAGCTG 
ATCCTACAGC AGTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236925.1
CDS	145..2862
Translation	MAESSESFSAASSPAPQRRRISDPLTSSPGRSSRRADALTSSPGRDLPPFEDESEGLLGTEGPVEEEEDGEELIGDGMERDYRPIPELDVYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRHIERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCSKCNFILGPFCQSQNQEVKPGSCPECQSTGPFEINMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTTNGFPVFATIILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKKDEGLTNGGTTEPAMPNTYGVEPLPQEVLKKYIIYAKERVRPKLNQMDQDKVARMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVMEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNDLLLFILKQLVAEQVTYQRNRFGAQQDTIEIPEKDLMDKARQINIHNLSAFYDSDLFKINKFSRDLKRKLILQQF

Target ORF information:

RefSeq Version	XM_006236863.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus minichromosome maintenance complex component 2 (Mcm2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236863.1

ORF Insert Sequence:

ATGGCGGAGT CTTCTGAGTC CTTCTCGGCA GCATCTAGCC CTGCCCCTCA GCGGCGACGG 
ATCAGTGATC CCCTCACTTC CAGCCCAGGC CGCAGCTCCA GACGTGCTGA CGCTCTTACC 
TCCAGCCCTG GCAGAGACCT CCCCCCATTT GAGGATGAGT CCGAGGGGCT GCTGGGCACG 
GAGGGGCCTG TGGAGGAAGA AGAGGATGGA GAGGAACTCA TTGGTGATGG CATGGAGAGA 
GACTACCGTC CCATTCCCGA GCTCGATGTC TACGAGGCAG AGGGATTGGC CCTGGATGAT 
GAAGATGTGG AGGAGCTGAC AGCCAGTCAG AGGGAGGCAG CTGAGCGGGC TATGAGGCAG 
CGGGACCGTG AGGCTGGCAG AGGCCTGGGT CGCATGCGTC GTGGGCTGCT GTATGACAGC 
GACGAAGAAG ATGAGGAGCG GCCTGCCCGT AAGCGCCGCC ACATAGAGCG TGCCACAGAG 
GATGGCGAGG AGGATGAAGA GATGATTGAG AGTATTGAGA ACCTGGAGGA CCTCAAGGGC 
CACTCGGTGC GAGAGTGGGT GAGCATGGCA GGGCCCAGAC TGGAGATCCA CCACCGTTTC 
AAGAACTTCT TGCGCACCCA CGTGGACAGC CATGGCCACA ACGTCTTCAA GGAGCGTATC 
AGTGATATGT GCAAAGAGAA CCGGGAGAGT TTGGTGGTAA ATTATGAAGA CCTGGCAGCC 
CGGGAACATG TGTTGGCATA CTTCCTACCC GAGGCACCCG CTGAGCTGCT GCAGATCTTC 
GATGAGGCTG CCCTGGAGGT TGTGCTGGCC ATGTACCCTA AATATGACCG CATCACCAAC 
CACATTCACG TGCGCATCTC CCACCTGCCT CTGGTGGAGG AGCTGCGTTC ACTGAGGCAG 
CTACACCTGA ACCAGCTCAT CCGTACCAGC GGTGTGGTGA CCAGCTGCAC TGGAGTCCTG 
CCCCAGCTCA GCATGGTCAA GTATAACTGT AGCAAGTGCA ACTTTATACT GGGGCCTTTC 
TGCCAGTCTC AGAACCAGGA GGTGAAGCCT GGTTCCTGCC CTGAGTGCCA GTCAACTGGG 
CCCTTTGAGA TCAACATGGA GGAGACCATC TATCAGAACT ACCAACGGAT CCGCATCCAG 
GAGAGTCCCG GCAAGGTGGC AGCTGGCCGG CTGCCCCGTT CCAAGGATGC CATCCTCCTT 
GCTGATCTGG TGGACAGCTG CAAGCCAGGA GACGAGATAG AGCTGACCGG CATTTACCAC 
AATAATTATG ATGGCTCACT TAACACCACC AACGGCTTTC CCGTCTTCGC CACCATCATC 
CTGGCCAACC ACGTTGCCAA GAAGGACAAC AAAGTGGCCG TGGGTGAGCT CACTGATGAG 
GACGTGAAGA TGATCACCAG TCTTTCCAAG GATCAGCAAA TCGGAGAGAA GATCTTTGCC 
AGCATTGCGC CCTCCATCTA TGGGCATGAA GACATCAAGA GAGGCCTGGC TCTGGCTCTG 
TTTGGAGGGG AGCCCAAGAA CCCAGGTGGA AAGCACAAAG TTCGAGGTGA CATCAATGTG 
CTCCTGTGTG GGGACCCTGG CACAGCGAAG TCCCAGTTCC TCAAATACAT CGAGAAAGTA 
TCTAGCCGTG CCATTTTCAC CACCGGCCAG GGTGCGTCAG CCGTGGGTCT CACAGCGTAT 
GTTCAGCGGC ATCCTGTCAG CAGAGAGTGG ACCTTAGAGG CTGGAGCCCT GGTTCTGGCC 
GACCGGGGAG TGTGTCTCAT TGATGAGTTT GACAAGATGA ATGACCAGGA CAGGACCAGC 
ATCCACGAGG CCATGGAGCA GCAAAGCATC TCCATCTCCA AGGCCGGCAT CGTTACCTCA 
CTGCAAGCCC GCTGCACCGT CATAGCTGCT GCCAACCCCA TAGGAGGCCG CTACGACCCT 
TCACTGACCT TCTCAGAGAA TGTAGACCTC ACAGAGCCCA TCATTTCCCG CTTTGATGTC 
CTGTGTGTGG TGAGGGACAC TGTTGATCCT GTTCAGGATG AGATGCTGGC CCGCTTTGTG 
GTTGGCAGCC ACGTCAGACA CCACCCCAGC AACAAGAAGG ACGAAGGGCT GACCAACGGT 
GGCACCACAG AGCCAGCCAT GCCCAACACA TACGGTGTGG AGCCCCTGCC TCAGGAGGTC 
CTGAAGAAGT ATATCATCTA TGCCAAGGAA CGGGTCCGCC CAAAGCTCAA CCAGATGGAC 
CAGGACAAAG TGGCCAGGAT GTACAGCGAC CTGAGGAAGG AGTCCATGGC AACGGGCAGT 
ATTCCCATCA CAGTGCGACA CATCGAGTCC ATGATCCGCA TGGCAGAGGC CCATGCACGC 
ATGCACCTGC GAGACTACGT GATGGAAGAT GATGTCAACA TGGCCATCCG CGTGATGCTG 
GAGAGCTTCA TTGACACCCA AAAGTTCAGT GTCATGCGCA GCATGCGCAA GACTTTTGCC 
CGGTATCTCT CCTTCCGTCG GGATAACAAT GACCTGCTGC TCTTCATACT GAAGCAGTTG 
GTGGCTGAGC AGGTGACATA CCAACGTAAC CGCTTTGGGG CCCAACAGGA CACCATCGAA 
ATACCTGAGA AGGACCTGAT GGACAAGGCC AGGCAGATCA ATATCCACAA CCTGTCCGCC 
TTCTACGACA GCGACCTCTT CAAAATCAAC AAGTTCAGCC GTGACCTGAA ACGCAAGCTG 
ATCCTACAGC AGTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Whole Exome Sequencing Identified MCM2 as a Novel Causative Gene for Autosomal Dominant Nonsyndromic Deafness in a Chinese Family.
PloS one10(7)e0133522(2015)
Gao J,Wang Q,Dong C,Chen S,Qi Y,Liu Y

Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons.
Proceedings of the National Academy of Sciences of the United States of America111(1)469-74(2014 Jan)
Huang W,She L,Chang XY,Yang RR,Wang L,Ji HB,Jiao JW,Poo MM

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication.
Science (New York, N.Y.)342(6155)239-42(2013 Oct)
Vannier JB,Sandhu S,Petalcorin MI,Wu X,Nabi Z,Ding H,Boulton SJ

Interactions of MCP1 with components of the replication machinery in mammalian cells.
International journal of biological sciences7(2)193-208(2011 Feb)
Bronze-da-Rocha E,Lin CM,Shimura T,Aladjem MI

Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease.
Aging1(4)382-8(2009 Apr)
Bonda DJ,Evans TA,Santocanale C,Llos? JC,Vi?a J,Bajic V,Castellani RJ,Siedlak SL,Perry G,Smith MA,Lee HG

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Mcm2 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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