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Zp2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Zp2
Entrez Gene ID 81828
Full Name zona pellucida glycoprotein 2
Synonyms Zp-2
General protein information
Preferred Names

zona pellucida glycoprotein 2

Names

zona pellucida sperm-binding protein 2
zona pellucida 2 glycoprotein
zona pellucida glycoprotein 2 (sperm receptor)
zona pellucida glycoprotein ZP2
zona pellucida protein A
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

1

1q36
Summary glycoprotein component of the zona pellucida [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_031150.1 NP_112412.1 zona pellucida sperm-binding protein 2 precursor

Pathways from BioSystems


Homologies


ZP2 XP_001091147.2
Canis lupus familiaris (dog) ZP2 NP_001003304.1
Gallus gallus (chicken) ZP2 NP_001034187.1
Xenopus tropicalis (tropical clawed frog) zp2 NP_988855.1
Pan troglodytes (chimpanzee) ZP2 XP_510869.3
Mus musculus (house mouse) Zp2 NP_035905.1
Homo sapiens (human) ZP2 NP_003451.1
Bos taurus (cattle) ZP2 NP_776398.1
Rattus norvegicus (Norway rat) Zp2 NP_112412.1

Gene Ontology


Bibliography

Related articles in PubMed

A common 'aggregation-prone' interface possibly participates in the self-assembly of human zona pellucida proteins.
Louros NN, Chrysina ED, Baltatzis GE, Patsouris ES, Hamodrakas SJ, Iconomidou VA
FEBS letters590(5)619-30(2016 Mar)

Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy.
Burkart AD, Xiong B, Baibakov B, Jim?nez-Movilla M, Dean J
The Journal of cell biology197(1)37-44(2012 Apr)

Recombinant human ZP3-induced sperm acrosome reaction: evidence for the involvement of T- and L-type voltage-gated calcium channels.
Jos? O, Hern?ndez-Hern?ndez O, Chirinos M, Gonz?lez-Gonz?lez ME, Larrea F, Almanza A, Felix R, Darszon A, Trevi?o CL
Biochemical and biophysical research communications395(4)530-4(2010 May)

ZP2 and ZP3 traffic independently within oocytes prior to assembly into the extracellular zona pellucida.
Hoodbhoy T, Avil?s M, Baibakov B, Epifano O, Jim?nez-Movilla M, Gauthier L, Dean J
Molecular and cellular biology26(21)7991-8(2006 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Zp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Zp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa07760 NM_031150.1
Latest version!		 Rattus norvegicus zona pellucida glycoprotein 2 (Zp2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00

ORF Online Only Promotion

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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa07760
Clone ID Related Accession (Same CDS sequence) NM_031150.1
Accession Version NM_031150.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2088bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-09
Organism Rattus norvegicus(Norway rat)
Product zona pellucida sperm-binding protein 2 precursor
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB000929.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB000929.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689601, SAMN02642731 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGGCTAGGT GGCAGAGAGT CTACTGGTTG CGTTCTCTCT TCTTCGCCCT TGTGACTTCA 
GTAAATTCAT TAAGCCTTCC TCAGTCAGAG AATCCTGCCT TCCCAGGCAC TCTCATTTGT 
GATAAAGATG AAGTGAGAGT AGAATTTTCA AGCAGATTTG ACATGGAAAA GTGGAATCCT 
TCCTTGGTGG ATACCTTTGG TAATGAAATT TCGAACTGCA CTTATGCTCT GGACTTGGAA 
AAGTTTATCC TGAAATTCCC TTACGAGACC TGTACTATAA AAGTGATTGG TGGATACCAG 
GTGAACATCA GAGTGCAGGA CACCAATGCT GATGTAAGCT ATAAAGATGA CGTGCATCAC 
TTTTTCTGCC CAGCTATTCA AGCAGAGATT CATGAGGTCT CAGAAATTGT TGTCTGCATG 
GAGGATCTCA TATCTTTTTC TTTCCCACAA CTTTTCTCTA GGCTTGCTGA TGAAAATCAG 
AATGTATCTG AGATGGGATG GATTATTAAG ATTGGCAATG GTACAAGAGT CCACACTCTG 
CCCCTGAAGG ATGCTATAGT ACAAGGATTT AATCTCCTGA TTGACAGCCA GAAAATAACC 
CTCCATGTGC CAGCCAATGC TACCGGAGTA GCTCACTATG TGCAAGAGAG CAGCTATCTC 
TATACTGTAC AGCTGAAGCT CTTGTTCTCA AGTCCTGGGC AGAAGATCAC CTTCTCTTCA 
CAAGCTATCT GTGCACCAGA TCTTTCTGTG GCTTGTAATG TGACACACAT GAGTCTTACT 
ATACCAGAAT TTCCTGGGAA GCTAAAATCT GTGGGCTTTG GACAAAGGAA CATCCCTGAG 
GATCAATGGC ATGCCAATGG AATTGACAAA GAAGCAACAA ATGGCTTGAG ACTGCATTTC 
AGAAAATCTC TCTTGAAGAC AAAACCCTCT GAAAAGTGTC CATTCTACCA GTTCTACTTC 
TCTTCACTCG AGCTGACCTT TAACTTCCAA GGGGACATGC TATCCACAGT GATTGATCCC 
GAGTGCCACT GTGAGTCACC GGTCTCCATA GATGAACTGT GTACACGGGA TGGGTTTATG 
GACTTTGAGG TCTACAGCCA CCAAACAAAA CCTGCACTAA ACCTGGAGAG CCTCCTGGTG 
GGAAACTCCT CCTGCCAGCC TATTTTCAAG GTTCAGTCTC TGGGGCTTGC AAGATTTCAC 
ATACCTCTGA ATGGATGTGG AACACGACAG AAATTTGAAG GTGATAAAGT CATCTATGAG 
AATGAAATCC ATGCTCTCTG GGAAAATCCA CCGTCAAACA TTATTTTCAG AAACAGTGAG 
TTCAGGATGA CCGTGAGATG CCATTACATC AGAGACAGTA TGCTACTAAG GGCCCATATC 
AAAAGCCATT CTTCTCCAGT GGCCTCTGTA AAGCCAGGTC CACTAGCGTT GGTCCTACAA 
ACCTACCCAG ACATATCCTA CCAACGGCCT TATAGGAAGA ATGAGTACCC TCTAGTGAGG 
TACCTCCGCC AGCCCATCTA CATGGAAGTG ACAGTCTTGA ATAGAAATGA TCCCAACATC 
AAGCTGGTTT TAGATGACTG CTGGGCAACA ACTTTTGAGG ACCCAGCCTC TGTCCCCCAG 
TGGCAGATCA TTATGGATGG CTGTGAATAT GAACTGGACA ATTACCGCAC TACTTTCCAC 
GCAGCCAACT CCTCTGCAGC CCATTCTGGT CACTACCAGA GGTTTGATGT GAAGACTTTT 
GCCTTTGTGT CAGAGTCTCG GGGGCTCTCC AGCCTGATCT ACTTCCACTG CAGTGCCTTG 
ATCTGTAACC AAGCCTCCCC TCTGTGCTCT GTGACTTGCC CTGCACCACT GAGGAACAAA 
CGAGAGGCCA GCAAAGAAGG CACAATGACG GTTAGCCTCC CAGGACCTAT TATCTTGTTG 
TCAGATGACT CTTCATCCAA AGGTGTAATG AACCCTGACA GCTATGAGAT TACCAAAGAT 
ATTGCTTCTA AAACATTGGG TGCTGTGGCT GCACTAGTGG GCTCAGCAGT CATCATAGGT 
TTCATCTGTT ACCTGCATAA GAAAAGAATT GTAAGGTTCA ATTCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_112412.1
CDS20..2107
Translation

Target ORF information:

RefSeq Version NM_031150.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus zona pellucida glycoprotein 2 (Zp2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_031150.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGGCTAGGT GGCAGAGAGT CTACTGGTTG CGTTCTCTCT TCTTCGCCCT TGTGACTTCA 
GTAAATTCAT TAAGCCTTCC TCAGTCAGAG AATCCTGCCT TCCCAGGCAC TCTCATTTGT 
GATAAAGATG AAGTGAGAGT AGAATTTTCA AGCAGATTTG ACATGGAAAA GTGGAATCCT 
TCCTTGGTGG ATACCTTTGG TAATGAAATT TCGAACTGCA CTTATGCTCT GGACTTGGAA 
AAGTTTATCC TGAAATTCCC TTACGAGACC TGTACTATAA AAGTGATTGG TGGATACCAG 
GTGAACATCA GAGTGCAGGA CACCAATGCT GATGTAAGCT ATAAAGATGA CGTGCATCAC 
TTTTTCTGCC CAGCTATTCA AGCAGAGATT CATGAGGTCT CAGAAATTGT TGTCTGCATG 
GAGGATCTCA TATCTTTTTC TTTCCCACAA CTTTTCTCTA GGCTTGCTGA TGAAAATCAG 
AATGTATCTG AGATGGGATG GATTATTAAG ATTGGCAATG GTACAAGAGT CCACACTCTG 
CCCCTGAAGG ATGCTATAGT ACAAGGATTT AATCTCCTGA TTGACAGCCA GAAAATAACC 
CTCCATGTGC CAGCCAATGC TACCGGAGTA GCTCACTATG TGCAAGAGAG CAGCTATCTC 
TATACTGTAC AGCTGAAGCT CTTGTTCTCA AGTCCTGGGC AGAAGATCAC CTTCTCTTCA 
CAAGCTATCT GTGCACCAGA TCTTTCTGTG GCTTGTAATG TGACACACAT GAGTCTTACT 
ATACCAGAAT TTCCTGGGAA GCTAAAATCT GTGGGCTTTG GACAAAGGAA CATCCCTGAG 
GATCAATGGC ATGCCAATGG AATTGACAAA GAAGCAACAA ATGGCTTGAG ACTGCATTTC 
AGAAAATCTC TCTTGAAGAC AAAACCCTCT GAAAAGTGTC CATTCTACCA GTTCTACTTC 
TCTTCACTCG AGCTGACCTT TAACTTCCAA GGGGACATGC TATCCACAGT GATTGATCCC 
GAGTGCCACT GTGAGTCACC GGTCTCCATA GATGAACTGT GTACACGGGA TGGGTTTATG 
GACTTTGAGG TCTACAGCCA CCAAACAAAA CCTGCACTAA ACCTGGAGAG CCTCCTGGTG 
GGAAACTCCT CCTGCCAGCC TATTTTCAAG GTTCAGTCTC TGGGGCTTGC AAGATTTCAC 
ATACCTCTGA ATGGATGTGG AACACGACAG AAATTTGAAG GTGATAAAGT CATCTATGAG 
AATGAAATCC ATGCTCTCTG GGAAAATCCA CCGTCAAACA TTATTTTCAG AAACAGTGAG 
TTCAGGATGA CCGTGAGATG CCATTACATC AGAGACAGTA TGCTACTAAG GGCCCATATC 
AAAAGCCATT CTTCTCCAGT GGCCTCTGTA AAGCCAGGTC CACTAGCGTT GGTCCTACAA 
ACCTACCCAG ACATATCCTA CCAACGGCCT TATAGGAAGA ATGAGTACCC TCTAGTGAGG 
TACCTCCGCC AGCCCATCTA CATGGAAGTG ACAGTCTTGA ATAGAAATGA TCCCAACATC 
AAGCTGGTTT TAGATGACTG CTGGGCAACA ACTTTTGAGG ACCCAGCCTC TGTCCCCCAG 
TGGCAGATCA TTATGGATGG CTGTGAATAT GAACTGGACA ATTACCGCAC TACTTTCCAC 
GCAGCCAACT CCTCTGCAGC CCATTCTGGT CACTACCAGA GGTTTGATGT GAAGACTTTT 
GCCTTTGTGT CAGAGTCTCG GGGGCTCTCC AGCCTGATCT ACTTCCACTG CAGTGCCTTG 
ATCTGTAACC AAGCCTCCCC TCTGTGCTCT GTGACTTGCC CTGCACCACT GAGGAACAAA 
CGAGAGGCCA GCAAAGAAGG CACAATGACG GTTAGCCTCC CAGGACCTAT TATCTTGTTG 
TCAGATGACT CTTCATCCAA AGGTGTAATG AACCCTGACA GCTATGAGAT TACCAAAGAT 
ATTGCTTCTA AAACATTGGG TGCTGTGGCT GCACTAGTGG GCTCAGCAGT CATCATAGGT 
TTCATCTGTT ACCTGCATAA GAAAAGAATT GTAAGGTTCA ATTCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

A common 'aggregation-prone' interface possibly participates in the self-assembly of human zona pellucida proteins.
FEBS letters590(5)619-30(2016 Mar)
Louros NN,Chrysina ED,Baltatzis GE,Patsouris ES,Hamodrakas SJ,Iconomidou VA


book

Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy.
The Journal of cell biology197(1)37-44(2012 Apr)
Burkart AD,Xiong B,Baibakov B,Jim?nez-Movilla M,Dean J


book

Recombinant human ZP3-induced sperm acrosome reaction: evidence for the involvement of T- and L-type voltage-gated calcium channels.
Biochemical and biophysical research communications395(4)530-4(2010 May)
Jos? O,Hern?ndez-Hern?ndez O,Chirinos M,Gonz?lez-Gonz?lez ME,Larrea F,Almanza A,Felix R,Darszon A,Trevi?o CL


book

ZP2 and ZP3 traffic independently within oocytes prior to assembly into the extracellular zona pellucida.
Molecular and cellular biology26(21)7991-8(2006 Nov)
Hoodbhoy T,Avil?s M,Baibakov B,Epifano O,Jim?nez-Movilla M,Gauthier L,Dean J