| Gene Symbol | RYR1 |
| Entrez Gene ID | 396718 |
| Full Name | ryanodine receptor 1 |
| Synonyms | CRC,RYR |
| Gene Type | protein-coding |
| Organism | Sus scrofa(Pig) |
| Genome |
IVD Raw Materials
ORF » Species Summary » Sus scrofa » RYR1 cDNA ORF clone
| Gene Symbol | RYR1 |
| Entrez Gene ID | 396718 |
| Full Name | ryanodine receptor 1 |
| Synonyms | CRC,RYR |
| Gene Type | protein-coding |
| Organism | Sus scrofa(Pig) |
| Genome |
| mRNA | Protein | Name |
|---|---|---|
| NM_001001534.1 | NP_001001534.1 | ryanodine receptor 1 |
| XM_013998383.1 | XP_013853837.1 | ryanodine receptor 1 isoform X1 |
The effects of ryanodine receptor (RYR1) mutation on natural killer cell cytotoxicity, plasma cytokines and stress hormones during acute intermittent exercise in pigs.
Ciepielewski ZM, Stojek W, Borman A, My?li?ska D, Pa?czy?ska P, Kamyczek M
Research in veterinary science10577-86(2016 Apr)
The effects of ryanodine receptor 1 (RYR1) mutation on plasma cytokines and catecholamines during prolonged restraint in pigs.
Ciepielewski ZM, Stojek W, Glac W, My?li?ska D, Kwaczy?ska A, Kamyczek M
Veterinary immunology and immunopathology156(3-4)176-81(2013 Dec)
Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density.
Biesmans L, Macquaide N, Heinzel FR, Bito V, Smith GL, Sipido KR
PloS one6(10)e25100(2011)
Site-specific modification of calmodulin Ca?(+) affinity tunes the skeletal muscle ryanodine receptor activation profile.
Jiang J, Zhou Y, Zou J, Chen Y, Patel P, Yang JJ, Balog EM
The Biochemical journal432(1)89-99(2010 Nov)
Interactions between genes involved in growth and muscularity in pigs: IGF-2, myostatin, ryanodine receptor 1, and melanocortin-4 receptor.
Stinckens A, Luyten T, Van den Maagdenberg K, Janssens S, De Smet S, Georges M, Buys N
Domestic animal endocrinology37(4)227-35(2009 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results suggest that the heterogeneity of immunological and neuroendocrine response to exercise stress in pigs could be influenced by RYR1 gene mutation.
Title: The effects of ryanodine receptor (RYR1) mutation on natural killer cell cytotoxicity, plasma cytokines and stress hormones during acute intermittent exercise in pigs.
Interleukin 1, IL-2, IL-10, and TNF-alpha measures were positively intercorrelated in each of the three RYR1 genotype group
Title: The effects of ryanodine receptor 1 (RYR1) mutation on plasma cytokines and catecholamines during prolonged restraint in pigs.
T-tubules proximity modulates RyR cluster properties resulting in intracellular heterogeneity of diastolic spark activity.
Title: Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density.
Results support the hypothesis that Ca(2)(+) binding to CaM's C-terminal acts as the switch converting CaM from a RyR1 activator into a channel inhibitor.
Title: Site-specific modification of calmodulin Ca?(+) affinity tunes the skeletal muscle ryanodine receptor activation profile.
The RYR1 genotype had a significant effect on IGF-2 expression in pig longissimus dorsi muscle.
Title: Interactions between genes involved in growth and muscularity in pigs: IGF-2, myostatin, ryanodine receptor 1, and melanocortin-4 receptor.
The following RYR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RYR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe00176 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001001534.1 | |
| Accession Version | NM_001001534.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 15108bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-18 | |
| Organism | Sus scrofa(pig) | |
| Product | ryanodine receptor 1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M91452.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M91451.1, M91452.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2040582, SAMEA2040586 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGGTGACG GAGGAGAGGG CGAAGATGAG GTCCAGTTTC TGCGGACAGA CGACGAGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001001534.1 |
| CDS | 130..15237 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001001534.1 |
1 | ATGGGTGACG GAGGAGAGGG CGAAGATGAG GTCCAGTTTC TGCGGACAGA CGACGAGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe36450 | |
| Clone ID Related Accession (Same CDS sequence) | XM_013998383.1 | |
| Accession Version | XM_013998383.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 15090bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2015-09-10 | |
| Organism | Sus scrofa(Pig) | |
| Product | ryanodine receptor 1 isoform X1 | |
| Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003610421.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGTGACG GAGGAGAGGG CGAAGATGAG GTCCAGTTTC TGCGGACAGA CGACGAGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_013853837.1 |
| CDS | 71..15160 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_013998383.1 |
1 | ATGGGTGACG GAGGAGAGGG CGAAGATGAG GTCCAGTTTC TGCGGACAGA CGACGAGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The effects of ryanodine receptor (RYR1) mutation on natural killer cell cytotoxicity, plasma cytokines and stress hormones during acute intermittent exercise in pigs. |
The effects of ryanodine receptor 1 (RYR1) mutation on plasma cytokines and catecholamines during prolonged restraint in pigs. |
Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density. |
Site-specific modification of calmodulin Ca?(+) affinity tunes the skeletal muscle ryanodine receptor activation profile. |
Interactions between genes involved in growth and muscularity in pigs: IGF-2, myostatin, ryanodine receptor 1, and melanocortin-4 receptor. |