Citations Database

GenScript services and products have been used extensively by scientists worldwide to improve their research efficiency. Here, we have collected a representation of citations for your reference.

Page: 2/536 Results per page

Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis

Authors: Li Wang; Mar a Guzman; Diego Mu oz-Santos; Jose Manuel Honrubia; Jorge Ripoll-Gomez; Rafael Delgado; Isabel Sola; Luis Enjuanes; Sonia Zu iga

Journal: Frontiers in cellular and infection microbiology

PubMed ID: 37942479

Doi: 10.3389/fcimb.2023.1268227

Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis

Authors: Li Wang; Mar a Guzman; Diego Mu oz-Santos; Jose Manuel Honrubia; Jorge Ripoll-Gomez; Rafael Delgado; Isabel Sola; Luis Enjuanes; Sonia Zu iga

Journal: Frontiers in cellular and infection microbiology

PubMed ID: 37942479

Doi: 10.3389/fcimb.2023.1268227

Predicting the Anti-SARS-CoV-2 Potential of Isoquinoline Alkaloids from Brazilian Siparunaceae Species Using Chemometric Tools

Authors: Brendo Araujo Gomes; Di gina Ara jo Fernandes; Simony Carvalho Mendon a; Mariana Freire Campos; Thamirys Silva da Fonseca; Larissa Esteves Carvalho Constant; Natalia Ferreira de Sousa; Renata Priscila Barros de Menezes; Beatriz Albuquerque Cust dio de Oliveira; Stephany da Silva Costa; Giovanna Barbosa Frensel; Alice Santos Rosa; Thamara Kelcya Fonseca Oliveira; Amanda Resende Tucci; J lia Nilo Henrique Lima; Vivian Neuza Santos Ferreira; Milene Dias Miranda; Diego Allonso; Marcus Tullius Scotti; Suzana Guimar es Leit o; Gilda Guimar es Leit o

Journal: International Journal of Molecular Sciences

PubMed ID: 39859347

Doi: 10.3390/ijms26020633

Products & Services: Peptide Synthesis

Predicting the Anti-SARS-CoV-2 Potential of Isoquinoline Alkaloids from Brazilian Siparunaceae Species Using Chemometric Tools

Journal: International Journal of Molecular Sciences

PubMed ID: 39859347

Doi: 10.3390/ijms26020633

Products & Services: Peptide Synthesis

Tuning the sensitivity of mechanosensory receptors through histidine scanning

Authors: Yuanhao Wang, Yuhan Wang, Wenjie Yuan, Mingyu Fan, Xiaojing Wang, Anhui Wang, Yanling Bao, Yajing Zhang, Jia Chi Tan, Jianglai Wang, Junshuang Liu, Tianqi Huang, Zixuan Han, Biling Pei, Lijuan Chen, Zhengxu Ren, Xueqing Wang, Lanxin Hu, Siqi Wu, Mengke Pang, Sifan Wang, Zihuan Yang, Jiaze Li, Delian Huang, Shuai Shao, Huairui Yuan, Ling Wu, Yinnian Feng, Penghui Zhou, Guohui Li, Bo Sun, Chenqi Xu, Nicholas R J Gascoigne, Xiang Zhao

Journal: Cell

PubMed ID: 41713420

Doi: 10.1016/j.cell.2025.12.050

Products & Services: Peptide Synthesis

Y-shaped nanoprobe-based DNA microarray for rapid detection of multiplex miRNAs with single-nucleotide specificity

Authors: Yichen Du, Rui Sun, Shuang Hao, Fuwan Yang, Qifei Hu, Ruyan Xue

Journal: Microchemical Journal

Doi: 10.1016/j.microc.2026.117169

Products & Services: Custom DNA/RNA Oligos

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

Authors: Chenqi Yu, Yang Liu, Kang Kang, Jianfeng Yu, Xiaowei Xia, Yaoge Deng, Yingjie Lu, Huilin Yang, Lisong Li, Wu Xu, Yijian Zhang, Xuesong Zhu

Journal: Advanced Science

PubMed ID: 41787915

Doi: 10.1002/advs.202520157

Products & Services: Protein Electrophoresis and Western

A biomimetic nanodisc system selectively activates type I interferons by nonclassical STING pathway for cancer immunotherapy

Authors: Qianwen Mu, Haolan Deng, Shuo Li, Xiaoyu An, Xuan Liu, Yue Xi, Hao Liang, Di Sun, Xiaojun Wang, Xue Liu, Gang Liu, Chao Liu

Journal: Nature Communications

PubMed ID: 41917023

Doi: 10.1038/s41467-026-71363-6

Products & Services: Peptide Synthesis Protein Electrophoresis and Western

High-Entropy Alloy Synergized with Gene Editing for Cocktail-Sensitized Radioimmunotherapy of Lung Metastases

Authors: Qianglan Lu, Chengwei Ye, Ruiyue Chen, Zhanqi Xing, Zhiyong Liu, Fei Zeng, Jinglang Gong, Yanfeng Gao, Xiaolian Sun, Shaochun Tang, Yujun Song

Journal: ADVANCED MATERIALS

PubMed ID: 41914367

Doi: 10.1002/adma.202522618

Products & Services: Synthetic Guide RNA

Structural insights into lipid membrane binding by human ferlins

Authors: Constantin Cretu; Aleksandar Chernev; Csaba Zolt n Kib di Szab ; Vladimir Pena; Henning Urlaub; Tobias Moser; Julia Preobraschenski

Journal: The EMBO Journal

PubMed ID: 40437073

Doi: 10.1038/s44318-025-00463-8

A Oligomer Dissociation Is Catalyzed by Fibril Surfaces

Authors: Alexander J. Dear; Dev Thacker; Stefan Wennmalm; Lei Ortigosa-Pascual; Ewa A. Andrzejewska; Georg Meisl; Sara Linse; Tuomas P. J. Knowles

Journal: ACS Chemical Neuroscience

PubMed ID: 38785363

Doi: 10.1021/acschemneuro.4c00127

A Oligomer Dissociation Is Catalyzed by Fibril Surfaces

Authors: Alexander J. Dear; Dev Thacker; Stefan Wennmalm; Lei Ortigosa-Pascual; Ewa A. Andrzejewska; Georg Meisl; Sara Linse; Tuomas P. J. Knowles

Journal: ACS Chemical Neuroscience

PubMed ID: 38785363

Doi: 10.1021/acschemneuro.4c00127

Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis

Authors: Andrew I Wong; Tiago Beites; Kyle A Planck; Rachael A Fieweger; Kathryn A Eckartt; Shuqi Li; Nicholas C Poulton; Brian C VanderVen; Kyu Y Rhee; Dirk Schnappinger; Sabine Ehrt; Jeremy Rock; Bavesh D Kana

Journal: Elife

PubMed ID: 36810158

Doi: 10.7554/eLife.81177

Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis

Journal: Elife

PubMed ID: 36810158

Doi: 10.7554/eLife.81177

Mechanistic insights into the small-molecule inhibition of influenza A virus entry

Authors: Yan Xu; Varada Anirudhan; Irina N. Gaisina; Haijuan Du; Saad Alqarni; Terry W. Moore; Michael Caffrey; Balaji Manicassamy; Tongqing Zhou; Lijun Rong; Kai Xu

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 40802690

Doi: 10.1073/pnas.2503899122

Deciphering the Mechanism: Overcoming Incompatibility for Continuous Cap‑1 mRNA Synthesis via Multienzyme Cascades

Authors: Shiyi Che, , Zhengjun Li, Zhiguo Su, Aibing Yu, Minsu Liu, and Songping Zhang

Journal: ACS Sustainable Chemistry & Engineering

Doi: 10.1021/acssuschemeng.5c12019

Products & Services: Gene Synthesis

Screening of a novel VHH pair targeting different epitopes of D-dimer and development of a sandwich luminex immunoassay for plasma D-dimer detection

Authors: Congcong Jia, Min Zhu, Yingtung Lo, Meixiang Yu, Xinyi Xia, Weiwei Ji, Xiang Cao, Yakun Wan, Jianzhong Lu, Hai Zhang

Journal: Analytica Chimica Acta

PubMed ID: 41903976

Doi: 10.1016/j.aca.2026.345368

Products & Services: Custom Vector Construction

mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy

Authors: Jiayan Fu, Yaoqi Liu, Zhenyu Zhong, Benyuan Cao, Luna Ran, Zijia Guo, Haiyang Dong, Nengcheng Bao, Rongqing Pan, Jinqiang Wang, Yuanhui Mao, Yongfeng Jin

Journal: Cell Reports Medicine

PubMed ID: 41916290

Doi: 10.1016/j.xcrm.2026.102706

Products & Services: Peptide Synthesis

GPR183 potentiates CAR-T cell infiltration and antitumor immunity through a positive feedback loop involving the oxysterol 7α,25-OHC

Authors: Rui Guo, Chang Guo, Sen Qin, Zhiwen Lin, Jinlian Tong, Yiran Wang, Zixuan Zhao, Wen Zuo, Qing Gao, Qin Tan, Jie Ma

Journal: Molecular cancer

PubMed ID: 41840629

Doi: 10.1186/s12943-026-02642-5

Products & Services: Synthetic Guide RNA Custom DNA/RNA Oligos

CellCousin2: an optimized system for partial ablation and tracing of regenerative lineages

Authors: Gabriel Garnik Hovhannisyan, Tawba Akhourbi, Sema Elif Eski, Isabelle Pirson, Esteban N Gurzov, Sumeet Pal Singh

Journal: NPJ Regenerative medicine

PubMed ID: 41912583

Doi: 10.1038/s41536-026-00473-y

Products & Services: Gene Fragments

Dihydrotanshinone as a Natural Product-Based CYP17A1 Lyase Inhibitor for Hyperandrogenic Disorders

Authors: Kaige Li; Jibira Yakubu; Flemming Steen J rgensen; Amit V. Pandey

Journal: Biomolecules

PubMed ID: 41594684

Doi: 10.3390/biom16010144

Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis

Authors: Li Wang; Mar a Guzman; Diego Mu oz-Santos; Jose Manuel Honrubia; Jorge Ripoll-Gomez; Rafael Delgado; Isabel Sola; Luis Enjuanes; Sonia Zu iga

Journal: Frontiers in cellular and infection microbiology

PubMed ID: 37942479

Doi: 10.3389/fcimb.2023.1268227

Epistasis in the receptor-binding domain of contemporary H3N2 viruses that reverted to bind sialylated di-LacNAc repeats

Authors: Ruonan Liang; Francesca Peccati; Niels L.D. Ponse; Elif Uslu; Annelies J.H. de Rooij; Alvin X. Han; Geert-Jan Boons; Luca Unione; Robert P. de Vries

Journal: Cell Reports

PubMed ID: 40679911

Doi: 10.1016/j.celrep.2025.116007

Mechanistic insights into the small-molecule inhibition of influenza A virus entry

Authors: Yan Xu; Varada Anirudhan; Irina N. Gaisina; Haijuan Du; Saad Alqarni; Terry W. Moore; Michael Caffrey; Balaji Manicassamy; Tongqing Zhou; Lijun Rong; Kai Xu

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 40802690

Doi: 10.1073/pnas.2503899122

89Zr/177Lu-Labeled Radioimmunoconjugates Targeting SORT1 for Cancer Theranostics

Authors: Jingyue Gao, Tianyi Cen, Junyi Chen, Xinwei Li, Xiaowei Fan, Mengxin Xu, Feng Gao, Zhibo Liu

Journal: Journal of Medicinal Chemistry

PubMed ID: 41773941

Doi: 10.1021/acs.jmedchem.6c00007

Products & Services: Custom Vector Construction

CRISPR/Cas9-Based Vanadium MXene-Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal-Induced Multi-Effect Synergistic Antitumor Therapy

Authors: Zi-Jian Huang, Feng-Ming Li, Yi-Fan Tu, Ke-Ke Feng, Cheng-Lei Li, Shi-Cheng Tian, Yong-Shan Hu, Jing-Wei Shao, Zhen-Hua Liu

Journal: Advanced Science

PubMed ID: 41818620

Doi: 10.1002/advs.202522535

Products & Services: Peptide Synthesis

Cyclic guanosine monophosphate-protein kinase G signaling attenuates aortic valve calcification through ULK1-mediated autophagy

Authors: Yan Wang, Fei Xu, Chengxiang Song, Xi Wang, Hao Zhou, Tianyi Qu, Hongde Li, Qiang Luo, Wenhua Lei, Yue Yin, Fangyang Huang, Mao Chen

Journal: Signal transduction and targeted therapy

PubMed ID: 41820291

Doi: 10.1038/s41392-026-02624-5

Products & Services: Custom mRNA synthesis

The mechanism of ribosomal recruitment during translation initiation on the Type 2 encephalomyocarditis virus IRES

Authors: Sayan Bhattacharjee, Irina S Abaeva, Zuben P Brown, Yani Arhab, Hengameh Fallah, Christopher U T Hellen, Joachim Frank, Tatyana V Pestova

Journal: The EMBO Journal

PubMed ID: 41851500

Doi: 10.1038/s44318-026-00735-x

Products & Services: Protein Electrophoresis and Western Mutagenesis Services

ZBTB16 controls the onset of Clostridium difficile colitis through the Pyrin inflammasome

Authors: Shuhui Li, Jingjing He, Huxidanmu Tuoheniyazi, Junrui Ma, Zhenyu Li, Juanjuan Zheng, Yuxin Wang, Xiupan Gao, Xiaobao Yang, Danping Liu, Yanan Zhao, Tongxuan Su, Yibing Peng, Dakang Xu, Xuefeng Fei

Journal: Pharmacological research

PubMed ID: 41666999

Doi: 10.1016/j.phrs.2026.108133

Products & Services: Protein Electrophoresis and Western

Regulated transformation system (RTS): sddi-mediated programmable shut-off and mode switching of base editors

Authors: Jiacheng Deng, Jian Zhou, Hongyong Xiang, Xueyuan Li, Xiang Han, Zhen Weng, Junbo Jia, Yingshuo Shao, Yang Sima, Ming Niu, Dongmeng Li, Hongsheng Ouyang, Bin Xu, Daxin Pang, Lin Yang, Hongming Yuan

Journal: Nucleic Acids Research

PubMed ID: 41909950

Doi: doi.org/10.1093/nar/gkag162

Products & Services: Gene Synthesis Codon Optimization

Sertoli Cell-Derived Extracellular Vesicles Orchestrate Cadmium-Induced Testicular Inflammation and Fibrosis

Authors: Jianfeng Ma, Mailin Gan, Shuang Liang, Siyu Chen, Ziling Hao, Yiting Yang, Jiawei Lu, Qihang Wu, Yuqian Shi, Lijun Sun, Jiaxin Li, Saihao Wang, Yan Wang, Xiaofeng Zhou, Lei Chen, Ye Zhao, Li Zhu, Linyuan Shen

Journal: Advanced Science

PubMed ID: 41881035

Doi: 10.1002/advs.202522278

Products & Services: Protein Electrophoresis and Western

Stabilization of erythrocyte membrane coating on nanoparticle via strong substrate interaction confers enhanced anti-α-hemolysin immunity

Authors: Jie Huang, Han Fu, Liyan Zhai, Shupeng Wang, Wende Fan, Haleh Alimohamadi, Hongyu Chen, Yue Zhang

Journal: Cell Biomaterials

Doi: 10.1016/j.celbio.2026.100412

Products & Services: Protein Electrophoresis and Western

AI-Enhanced Adaptive Virtual Screening Platform Enabling Exploration of 69 Billion Molecules Discovers Structurally Validated FSP1 Inhibitors

Authors: Domiziana Cecchini; AkshatKumar Nigam; Ming Tang; Joana Reis; Matt Koop; Andrea Gottinger; Callum Robert Nicoll; Yao Wang; Abhilash Jayaraj; S leyman Selim naro lu; Ricarda T rner; Yehor Malets; Minko Gehev; Krishna M. Padmanabha Das; Kelly Churion; Jongwan Kim; Nidhin Thomas; Yong Li; Hyuk-Soo Seo; Sirano Dhe-Paganon; Christopher Secker; Mohammad Haddadnia; Alexander Hasson; Minkai Li; Abhishek Kumar; Roni Levin-Konigsberg; Eun-Bee Choi; Geoffrey I. Shapiro; Huel Cox; Luke Sebastian; Chelsea Braithwaite; Puspalata Bashyal; Dmytro S. Radchenko; Aditya Kumar; Lei Yang; Pierre-Yves Aquilanti; Henry Gabb; Amr Alhossary; Gerhard Wagner; Al n Aspuru-Guzik; Yurii S. Moroz; Charalampos G. Kalodimos; Konstantin Fackeldey; John D. Schuetz; Andrea Mattevi; Haribabu Arthanari; Christoph Gorgulla

Journal: biorxiv

PubMed ID: 41929058

Doi: 10.1101/2023.04.25.537981

Structural insights into lipid membrane binding by human ferlins

Authors: Constantin Cretu; Aleksandar Chernev; Csaba Zolt n Kib di Szab ; Vladimir Pena; Henning Urlaub; Tobias Moser; Julia Preobraschenski

Journal: The EMBO Journal

PubMed ID: 40437073

Doi: 10.1038/s44318-025-00463-8

A Oligomer Dissociation Is Catalyzed by Fibril Surfaces

Authors: Alexander J. Dear; Dev Thacker; Stefan Wennmalm; Lei Ortigosa-Pascual; Ewa A. Andrzejewska; Georg Meisl; Sara Linse; Tuomas P. J. Knowles

Journal: ACS Chemical Neuroscience

PubMed ID: 38785363

Doi: 10.1021/acschemneuro.4c00127

Semaphorin 3A Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration

Authors: Yolanda P rez; Roman Bonet; Miriam Corredor; Cecilia Domingo; Alejandra Moure; ngel Messeguer; Jordi Bujons; Ignacio Alfonso

Journal: Pharmaceuticals

PubMed ID: 34577606

Doi: 10.3390/ph14090906

Products & Services: Peptide Synthesis

Semaphorin 3A Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration

Authors: Yolanda P rez; Roman Bonet; Miriam Corredor; Cecilia Domingo; Alejandra Moure; ngel Messeguer; Jordi Bujons; Ignacio Alfonso

Journal: Pharmaceuticals

PubMed ID: 34577606

Doi: 10.3390/ph14090906

Products & Services: Peptide Synthesis

Semaphorin 3A Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration

Authors: Yolanda P rez; Roman Bonet; Miriam Corredor; Cecilia Domingo; Alejandra Moure; ngel Messeguer; Jordi Bujons; Ignacio Alfonso

Journal: Pharmaceuticals

PubMed ID: 34577606

Doi: 10.3390/ph14090906

Products & Services: Peptide Synthesis

Dihydrotanshinone as a Natural Product-Based CYP17A1 Lyase Inhibitor for Hyperandrogenic Disorders

Authors: Kaige Li; Jibira Yakubu; Flemming Steen J rgensen; Amit V. Pandey

Journal: Biomolecules

PubMed ID: 41594684

Doi: 10.3390/biom16010144

Epistasis in the receptor-binding domain of contemporary H3N2 viruses that reverted to bind sialylated di-LacNAc repeats

Authors: Ruonan Liang; Francesca Peccati; Niels L.D. Ponse; Elif Uslu; Annelies J.H. de Rooij; Alvin X. Han; Geert-Jan Boons; Luca Unione; Robert P. de Vries

Journal: Cell Reports

PubMed ID: 40679911

Doi: 10.1016/j.celrep.2025.116007

Epistasis in the receptor-binding domain of contemporary H3N2 viruses that reverted to bind sialylated di-LacNAc repeats

Authors: Ruonan Liang; Francesca Peccati; Niels L.D. Ponse; Elif Uslu; Annelies J.H. de Rooij; Alvin X. Han; Geert-Jan Boons; Luca Unione; Robert P. de Vries

Journal: Cell Reports

PubMed ID: 40679911

Doi: 10.1016/j.celrep.2025.116007

Ferrous fluoride nanoinitiators reprogram tumor stemness to empower ultrasound-augmented pyroptosis for potent catalytic immunotherapy

Authors: Shumin Sun, Nailin Yang, Jihu Nie, Zifan Pei, Chunjie Wang, Zixian Yang, Zhihui Han, Yichi Cai, Liang Cheng

Journal: Biomaterials

PubMed ID: 40885147

Doi: 10.1016/j.biomaterials.2025.123652

Products & Services: Protein Electrophoresis and Western

Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis

Journal: Elife

PubMed ID: 36810158

Doi: 10.7554/eLife.81177

Chemoenzymatic synthesis of K29/K48-branched ubiquitin chains using LbPro* andOaAEP1 enzymes

Authors: Hongyi Cai, Xiangwei Wu, Shidian Wu, Lei Liu, Man Pan

Journal: CCS Chemistry

Doi: 10.31635/ccschem.026.202506451

Products & Services: Protein Electrophoresis and Western

Elucidating the Molecular Mechanism of 3D1 Antibody Binding to a Swine Enteric Coronavirus Antigen

Authors: Liangminghui Zhang, Ze Liang, Guang Yang, Lei Yan

Journal: Viruses

PubMed ID: 41754551

Doi: 10.3390/v18020208

Products & Services: Peptide Synthesis

ITGB1 Regulates Triple-Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Authors: Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T Rosen, Yingyu Wang, Chun-Wei D Chen, Cheng Zhang, Mingye Feng

Journal: Advanced Science

PubMed ID: 41632816

Doi: 10.1002/advs.202513672

Triglycerides induce endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity

Authors: Han Wu, Qing Shui, Xiaoxi Luan, Kexin Wang, Wei Zhao, Xiaopeng Qi, Bingyu Liu, Wanwei Sun, Chengjiang Gao

Journal: Molecular Therapy

PubMed ID: 41678331

Doi: 10.1016/j.celrep.2026.116976

Products & Services: Recombinant Proteins

An orthogonal CRISPR/Cpf1 platform for precise spatiotemporal gene regulation and osteoporotic fracture repair

Authors: Jie Zhao, Zengliang Wang, Lina Lu, Guoyun Bu, Zukang Miao, Yang Zhang, Yue Guo, Zhao Yang, Jianxiong Ma, Jun Jiao, Xinlong Ma

Journal: Molecular Therapy

PubMed ID: 41679307

Doi: 10.1016/j.crmeth.2025.101299

Phloretin targeting the 3CLpro Cys144 exhibits broad-spectrum antiviral activity against swine enteric coronavirus

Authors: Jiawei Xiao, Donghua Guo, Xiaoxu Xing, Limin Jiang, Shanshan Qi, Jun Wang, Wenfei Bai, Shiping Yu, Fanbo Shen, Xingyang Guo, Xinglin Wang, Wei Zhou, Hansong Li, Feiyu Zhao, Li Feng, Jialin Zhang, Yaru Xu, Dan Yang, Haixin Liu, Dongbo Sun

Journal: Molecular Therapy

PubMed ID: 41720346

Doi: 10.1016/j.virs.2026.02.011

Products & Services: Peptide Synthesis

Taming immune responses to AAV gene therapy by programmed in vivo Treg expansion

Authors: Lavesh Gwalani, Mincheol Park, Alexandra B Ysasi, Mona Motwani, Robert Jackson, Jie Bu, Zhengyu Luo, John Bladon, Edith L Pfister, Christian Mueller, Sourav R Choudhury

Journal: Molecular Therapy

PubMed ID: 41691369

Doi: 10.1016/j.ymthe.2026.02.019

Products & Services: Peptide Library Services

Personalized structural biology reveals the molecular mechanisms underlying heterogeneous epileptic phenotypes caused by de novo KCNC2 variants

Authors: Souhrid Mukherjee; Thomas A. Cassini; Ningning Hu; Tao Yang; Bian Li; Wangzhen Shen; Christopher W. Moth; David C. Rinker; Jonathan H. Sheehan; Joy D. Cogan; John H. Newman; Rizwan Hamid; Robert L. Macdonald; Dan M. Roden; Jens Meiler; Georg Kuenze; John A. Phillips; John A. Capra

Journal: Human Genetics and Genomics Advances

PubMed ID: 36035247

Doi: 10.1016/j.xhgg.2022.100131

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In-silico and in-vitro study of novel antimicrobial peptide AM1 from Aegle marmelos against drug-resistant Staphylococcus aureus

Authors: Rudra Awdhesh Kumar Mishra; Gothandam Kodiveri Muthukaliannan

Journal: Scientific REPORTS

PubMed ID: 39468175

Doi: 10.1038/s41598-024-76553-0

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In-silico and in-vitro study of novel antimicrobial peptide AM1 from Aegle marmelos against drug-resistant Staphylococcus aureus

Authors: Rudra Awdhesh Kumar Mishra; Gothandam Kodiveri Muthukaliannan

Journal: Scientific REPORTS

PubMed ID: 39468175

Doi: 10.1038/s41598-024-76553-0

Products & Services: Peptide Synthesis

From Field Overexpression to Biochemical Function: PxCYP6B4 Mediated Hydroxylation Confers Pyrethroid Resistance in Plutella xylostella

Authors: Zhuoda Liu, Yifei Zhou, Dongliang Wang, Ruichi Li, Zhen Tian, Yifan Li, Jiyuan Liu

Journal: Journal of Agricultural and Food Chemistry

PubMed ID: 41645610

Doi: 10.1021/acs.jafc.6c00843

Products & Services: Gene Synthesis Codon Optimization

Protein delivery to the eye: assessing therapeutic potential across inner and outer retina

Authors: Giuditta Dal Cortivo, Carmen Longo, Brigitte Müller, Anna Avesani, Raffaella Pacchiana, Maria Weller, Valerio Marino, Lyubomyr Lytvynchuk, Knut Stieger, Daniele Dell'Orco

Journal: International journal of pharmaceutics

PubMed ID: 41500346

Doi: doi.org/10.1016/j.ijpharm.2026.126568

Products & Services: PCR Cloning and Subcloning

Local antibody feedback enforces a checkpoint on affinity maturation in the germinal center and promotes epitope spreading

Authors: Yu Yan, Xuesong Wang, Zhenfei Xie, Daniel L V Bader, Ryan H Lim, Krystal M Ma, Christopher A Cottrell, Jon M Steichen, Liling Xu, Paula M Villavicencio, Madhav Akauliya, Ja-Hyun Koo, Jacqueline Ming Shen, Alexandra Vernich, Oleksandr Kalyuzhniy, Joel D Allen, Ali A Albowaidey, Anthony Alicea, Bingxian Chen, Erik Georgeson, Jordan Renae Ellis-Pugh, Nushin Alavi, Abigail Esposito, Hannah Naili, Nicole Phelps, Brendon Kelley, Michael Kubitz, Quynh Anh Phan, Alessia Liguori, Thavaleak Prum, Ryan Tingle, Danny Lu, Saman Eskandarzadeh, Xiaotie Liu, John E Warner, Stephanie R Weldon, Sunny Himansu, Max Crispin, Usha Nair, Sophia Liu, William R Schief, Facundo D Batista

Journal: Immunity

PubMed ID: 41690309

Doi: 10.1016/j.immuni.2026.01.011

Selective Targeting of Immune Checkpoints HLA-G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Authors: Lisa J Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer

Journal: Advanced Science

PubMed ID: 41662489

Doi: 10.1002/advs.202521448

Attenuation of Influenza a Virus into Live Vaccines Through C-End Degrons

Authors: Ping Wang, Le Li, Yunfang Chen, Le Tong, Zhen Li, Rong Yu, Quan Shen, Qikai Wang, Jihuan Hou, Qisi Zhang, Xu Si, Ning Wang, Demin Zhou, Wen-Xia Tian, Longlong Si

Journal: Advanced Science

PubMed ID: 41721587

Doi: 10.1002/advs.202509425

Products & Services: Peptide Synthesis

A near-complete map of human cytosolic degrons and their relevance for disease

Authors: Vasileios Voutsinos, Kristoffer E Johansson, Fia B Larsen, Martin Grønbæk-Thygesen, Nicolas Jonsson, Emma Holm-Olesen, Giulio Tesei, Amelie Stein, Douglas M Fowler, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

Journal: SCIENCE ADVANCES

PubMed ID: 41650254

Doi: 10.1126/sciadv.adz3483

E711-19 placement and orientation dictate CD8+ T cell response in structurally defined spherical nucleic acid vaccines

Authors: Jeongmin Hwang, Tonatiuh A Ocampo, Vinzenz Mayer, Janice Kang, Krishna S Paranandi, Young Jun Kim, Zhenyu Han, John P Cavaliere, Sergej Kudruk, Jochen H Lorch, Chad A Mirkin

Journal: SCIENCE ADVANCES

PubMed ID: 41671353

Doi: 10.1126/sciadv.aec3876

Products & Services: Peptide Synthesis

Disrupted energy metabolism is associated with retinal ganglion cell degeneration in autosomal dominant optic atrophy

Authors: Eugene Yu-Chuan Kang, Yun-Ju Tseng, Wei-Hao Peng, Hui-Chuan Hung, Pei-Hsuan Lin, Katrina P Montales, Emmet Sherman, John Peregrin, Ethan Hunghsi Wang, Chunya Kang, Yu-Chuan Teng, Chen-Yang Huang, Chia-Lung Tsai, Ian Yi-Feng Chang, Jiazhang Chen, Gülgün Tezel, Ye He, Tai-De Li, Linsey Stiles, Orian Shirihai, Stephen H Tsang, Chi-Chun Lai, Chi-Neu Tsai, Chyuan-Sheng Lin, Nan-Kai Wang

Journal: SCIENCE ADVANCES

PubMed ID: 41706861

Doi: 10.1126/sciadv.adx7815

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Sudden death-associated KCNH2 variants exert opposing effects on a nuclear subdomain of the cardiac potassium channel hERG1

Authors: Francisco G Sanchez-Conde, Matthew R Goodrich, Olivia M Stack, Louis N R Goldberg, Pamela K Ruzycki, Abhilasha Jain, Eric N Jimenez-Vazquez, David K Jones

Journal: Molecular Therapy

PubMed ID: 41708004

Doi: 10.1016/j.jbc.2026.111296

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AE-MXene-modified titanium alloy promotes osseointegration by regulating the AMPKMTOR-autophagy pathway in macrophage

Authors: Rui Chao, Lei Sun, Xinyu Xu, Zhan Liu, Xinyi Xu, Zhen Ren, Xinwei Chen, Weifeng Xu, Xuzhuo Chen, Ying Hu, Shanyong Zhang

Journal: Journal of nanobiotechnology

PubMed ID: 41634773

Doi: 10.1186/s12951-026-04080-3

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Adenine Base Editing Potently Suppresses Hepatitis B Surface Antigen Expression and Inhibits Hepatitis D Virus Release

Authors: Anuj Kumar, Emmanuel Combe, Elena M Smekalova, Selam Dejene, Dominique Leboeuf, Chao-Ying Chen, Léa Mougené, Marine Deleume, Caroline Scholtes, Marie-Laure Plissonnier, Xavier Grand, Maria G Martinez, Giuseppe Ciaramella, Francine Gregoire, Michael S Packer, Barbara Testoni, Fabien Zoulim

Journal: bioRvix

PubMed ID: 41676540

Doi: 10.64898/2026.02.06.704371

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SmCPK20 phosphorylates SmWRKY2 to regulate jasmonate-mediated tanshinone synthesis in Salvia miltiorrhiza

Authors: Xueying Li, Xiumin Nie, Bolun Li, Xi Han, Xiaona Cai, Qian Yao, Junwen Bu, Jiulin Huang, Bin Zhang, Juane Dong

Journal: Journal of integrative plant biology

PubMed ID: 41736258

Doi: 10.1111/jipb.70195

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Abstract Supplement Abstracts from AIDS 2022 the 24th International AIDS Conference, 29 July 2 August 2022, Montr al, Canada & Virtual

Authors:

Journal: Journal of the International AIDS Society

PubMed ID: 35916394

Doi: 10.1002/jia2.25935

ReCHEMbinant stapling enhances intracellular delivery and bioactivity of engineered protein inhibitors

Authors: Jan Pascal Kahler; Brecht D. Ellenbroek; Vera E. van der Noord; Bob van de Water; Sebastian J. Pomplun

Journal: Chem

PubMed ID: 41971978

Doi: 10.1016/j.chempr.2025.102839

MicroRNA-375-3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Authors: Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li

Journal: Advanced Science

PubMed ID: 41674346

Doi: 10.1002/advs.202513486

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Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Authors: Lyuba Y Salih, Nicolas L A Dumaire, Clémence Gieré, Erin Vest, Haya Alkhateeb, Christian P Moritz, Yannick Tholance, Jean-Philippe Camdessanché, Jean-Christophe Antoine, Jérôme Honnorat, Jafar Kafaie, Liberty François-Moutal, Aubin Moutal

Journal: Advanced Science

PubMed ID: 41700748

Doi: 10.1002/advs.202511413

Anticodon-edited transfer RNAs (ACE-tRNAs) encoded as therapeutic nonviral minimal DNA vectors

Authors: Joseph J Porter, Wooree Ko, Emily G Sorensen, Zachary Cheung, Kari Thrasher, Tyler Couch, Jeffrey T Gabell, Victoria Shwe, Julia Hyatt, Jennasea B Licata, Luke K Peterson, David A Dean, John D Lueck

Journal: Nucleic Acids Research

PubMed ID: 41641696

Doi: 10.1093/nar/gkag082

A novel two-component system regulates shikimate pathway for thermal adaptation in Thermus thermophilus

Authors: Xuying Bu, Yuwen Guo, Xiangyu Tian, Yuan Shao, Changyou Li, Pan Zhang, Yunxiang Liang, Yingjun Li

Journal: Nucleic Acids Research

PubMed ID: 41693563

Doi: 10.1093/nar/gkag116

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Divergent stem cell mechanisms govern the primary body axis and appendage regeneration in the axolotl

Authors: Liqun Wang, Li Song, Chao Yi, Jing Zhou, Zhouying Yong, Yan Hu, Xiangyu Pan, Na Qiao, Hao Cai, Wandong Zhao, Rui Zhang, Lieke Yang, Lei Liu, Guangdun Peng, Elly M Tanaka, Hanbo Li, Yanmei Liu, Ji-Feng Fei

Journal: SCIENCE ADVANCES

PubMed ID: 41650255

Doi: 10.1126/sciadv.adx5697

Structural basis for domain coupling in heteromeric glycine receptors revealed by an atypical allosteric agonist

Authors: Eric Gibbs, Bjarne Feddersen, Kayla J Kindig, David Seiferth, Philip C Biggin, Sudha Chakrapani

Journal: SCIENCE ADVANCES

PubMed ID: 41686897

Doi: 10.1126/sciadv.aeb2036

The RNA methyltransferase NSUN2 catalyzes 5-methylcytosine (m5C) on IL1B mRNA to promote transcript stability

Authors: Jiayun Wang, Lingyan Yan, Rong Jia, Jihua Guo

Journal: Molecular Therapy

PubMed ID: 41707999

Doi: 10.1016/j.jbc.2026.111290

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Genome-Wide Identification, Characterization, Expression Analysis, and Interacting Protein Prediction of the GSK3/Shaggy-like Gene Family in Watermelon

Authors: Peng Tian, Jingjing Zhang, Bowen Liu, Xiurui Gao, Bing Li, Wei Liu and Yanrong Wu

Journal: Plants-Basel

Doi: 10.3390/plants15030484

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Mycobacterium tuberculosis assembles a unique hexameric E2p core of the pyruvate dehydrogenase complex

Authors: Hao-Chi Hsu, Isabelle Bonnet, Ruslana Bryk, Huilin Li

Journal: Molecular Therapy

PubMed ID: 41690596

Doi: 10.1016/j.jbc.2026.111284

A Specific Sinorhizobium Flagellin Suppresses Legume Nodulation Through Immune Activation

Authors: Li Liu, Yaohua Li, Shuangcheng Ye, Chuanzheng Wei, Ziang Yan, Huanhui Yang, Hui Zhu, Gary Stacey, Yangrong Cao

Journal: Plant Biotechnology Journal

PubMed ID: 41636391

Doi: 10.1111/pbi.70576

Precise and efficient DNA base editing restores normal hearing in adult DFNB9 mouse model

Authors: Ziyu Zhang, Man Wang, Fangzhi Tan, Liyan Zhang, Xiaohan Wang, Xiangyan Chen, Jia Han, Nianci Li, Qiuhan Sun, Yicheng Lu, Zhiping Cui, Zuhong He, Jieyu Qi, Renjie Chai

Journal: Med

PubMed ID: 41763223

Doi: 10.1016/j.medj.2026.101001

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Systematic analysis of functional genetic and epigenetic variants in colorectal cancer

Authors: Erfei Chen, Qiqi Yang, Haoyang Dai, Yixin Chen, Yihui Zhang, Qianglong Wang, Rongrong Hou, Ming Chen, Jie Wang, Qianwen Xie, Wenju Sun, Yong-Qiang Ning, Ligang Fan, Jian Yan

Journal: SCIENCE ADVANCES

PubMed ID: 41719390

Doi: https://doi.org/10.1126/sciadv.aeb2473

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Abstract Supplement Abstracts from AIDS 2022 the 24th International AIDS Conference, 29 July 2 August 2022, Montr al, Canada & Virtual

Authors:

Journal: Journal of the International AIDS Society

PubMed ID: 35916394

Doi: 10.1002/jia2.25935

Computational engineering of the polyester hydrolase PHL7 for efficient poly(ethylene terephthalate) degradation in biocatalytic recycling processes

Authors: Paula Bl zquez-S nchez; Jonas Gunkel; Abibe Useini; Alexander Zlobin; Jonathan D. Zakary; Andrea Sch ler; Norbert Graefe; Felipe Engelberger; Filipa Cantanhede; Ronny Frank; Ziyue Zhao; Afsaneh Zarei; Erik Butensch n; J rg Matysik; Wolfgang Zimmermann; Norbert Str ter; Christian Sonnendecker; Georg K nze

Journal: Nature Communications

PubMed ID: 42140896

Doi: 10.1038/s41467-026-70868-4

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Personalized structural biology reveals the molecular mechanisms underlying heterogeneous epileptic phenotypes caused by de novo KCNC2 variants

Journal: Human Genetics and Genomics Advances

PubMed ID: 36035247

Doi: 10.1016/j.xhgg.2022.100131

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In-silico and in-vitro study of novel antimicrobial peptide AM1 from Aegle marmelos against drug-resistant Staphylococcus aureus

Authors: Rudra Awdhesh Kumar Mishra; Gothandam Kodiveri Muthukaliannan

Journal: Scientific REPORTS

PubMed ID: 39468175

Doi: 10.1038/s41598-024-76553-0

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Abstract Supplement Abstracts from AIDS 2022 the 24th International AIDS Conference, 29 July 2 August 2022, Montr al, Canada & Virtual

Authors:

Journal: Journal of the International AIDS Society

PubMed ID: 35916394

Doi: 10.1002/jia2.25935

Computational engineering of the polyester hydrolase PHL7 for efficient poly(ethylene terephthalate) degradation in biocatalytic recycling processes

Journal: Nature Communications

PubMed ID: 42140896

Doi: 10.1038/s41467-026-70868-4

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ReCHEMbinant stapling enhances intracellular delivery and bioactivity of engineered protein inhibitors

Authors: Jan Pascal Kahler; Brecht D. Ellenbroek; Vera E. van der Noord; Bob van de Water; Sebastian J. Pomplun

Journal: Chem

PubMed ID: 41971978

Doi: 10.1016/j.chempr.2025.102839

In-silico and in-vitro study of novel antimicrobial peptide AM1 from Aegle marmelos against drug-resistant Staphylococcus aureus

Authors: Rudra Awdhesh Kumar Mishra; Gothandam Kodiveri Muthukaliannan

Journal: Scientific REPORTS

PubMed ID: 39468175

Doi: 10.1038/s41598-024-76553-0

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Enhancing the efficiency of nuclease-based prime editing in rice with the Tf1 reverse transcriptase

Authors: Guigen Ma, Hao Xu, Sujie Zhang, Xueqi Li, Jiaqiang Liu, Jiayue Xie, Fang Yan, Huanbin Zhou

Journal: aBIOTECH

PubMed ID: 41938355

Doi: 10.1016/j.abiote.2026.100026

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Nanobody-Based Bioconjugates as Potent and Broadly Active Inhibitors of HIV Entry

Authors: Shubhra Jyoti Saha, Rashmi Kumariya, Phoenix A Davis, Emily Tourtellott, Nicole Doria-Rose, Carole A Bewley, Ross W Cheloha

Journal: Journal of the American Chemical Society

PubMed ID: 41592176

Doi: 10.1021/jacs.5c22670

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PD-L1-Binding Antigen Presenters: Redirecting Vaccine-Induced Antibodies for Cancer Immunotherapy

Authors: Huixin Gao, Lijuan Lu, Xiaoxiao Xiong, Yi Li, Donghui Hu, Duo Zhang, Zhiwei Feng, Cong Liu, Nannan Liu, Xiaoli Li, Jizhou Tan, Ting Liu, Ling Peng, Lu Lu, Huiyi Feng, Yan Zhong, Guisen Tan, Zhicheng Zhang, Liqin Huang, Chao Su, Ying Xue, Shuo Song, Wenxia Fan, Wei Wang, Fan Zou

Journal: Advanced Science

PubMed ID: 41668552

Doi: 10.1002/advs.202519574

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cPLA2α targeting to exosomes connects nuclear deformation to LTB4-signaling during neutrophil chemotaxis

Authors: Subhash B Arya, Fatima Jordan-Javed, Kristen Loesel, Yehyun Choi, Samuel P Collie, Lauren E Hein, Brendon M Baker, Euisik Yoon, Carole A Parent

Journal: SCIENCE ADVANCES

PubMed ID: 41719396

Doi: 10.1126/sciadv.aea2784

Trypanosome histone variants H3.V and H4.V promote nucleosome plasticity in repressed chromatin

Authors: Gauri Deák, Hayden Burdett, James A Watson, Marcus D Wilson

Journal: Molecular Therapy

PubMed ID: 41709455

Doi: 10.1016/j.str.2026.01.008

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Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer

Authors: Zecheng Yang, Madelaine S Theardy, Shuaitong Chen, Yongkun Wei, Mitsunobu Takeda, Yue Zeng, Xiaofei Wang, Jun Yao, Jennifer Li, Prapassorn Thirasastr, Jangho Park, Yangxi Zheng, Long T Vien, Khalida M Wani, Huamin Wang, Sisi Gao, Tim Heffernan, Lawrence Kwong, Ignacio I Wistuba, Laura Bover, Giulio F Draetta, Haoqiang Ying, Wantong Yao

Journal: Molecular Therapy

PubMed ID: 41707651

Doi: 10.1016/j.xcrm.2026.102613

OsWRKY53-OsGT1 Module Regulates Rice Tiller Development and Is Involved in Fine-Tuning Strigolactone Signaling

Authors: Jiaqi Tang, Guilong Zhao, Jiangli Yang, Zhuo Chen, Zhipeng Hong, Xin Jin, Ziming Qiu, Zhenyu Wang, Xiufeng Li, Jijun Yan, Changhua Liu, Weiqiang Li, Jinfang Chu, Yuanhu Xuan, Xiaojie Tian, Qingyun Bu

Journal: Plant Biotechnology Journal

PubMed ID: 41641886

Doi: 10.1111/pbi.70578

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A tripartite AAV System with Engineered Lox Sites Enables Efficient Delivery of the EYS Gene for Retinal Gene Therapy

Authors: Kun-Do Rhee, Poppy Datta, Clairissa Baccam, Seongjin Seo

Journal: Human gene therapy

PubMed ID: 41714294

Doi: 10.11710430342261426597

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A novel alphavirus-based saRNA platform for enhanced vaccination efficacy and organ-specific targeting

Authors: Zhen Sun, Yuxiao Liu, Haoyi Zhang, Ting Ge, Yuting Pan, Yang Liu, Miaomiao Wu, Tao Shan, Guoqiang Zhu, Qi Wu, Kangming Chen

Journal: Vaccine

PubMed ID: 41349243

Doi: 10.1016/j.vaccine.2025.128055

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Rapid discovery of repurposed drugs targeting SARS-CoV-2 spike HR1 by DNA-encoded library screening

Authors: Qingao Xue, Ze Liang, Yi Zhang, Fei Wang, Fulian Wang, Lili Liu, Guang Yang, Lei Yan

Journal: Bioorganic Chemistry

PubMed ID: 41691755

Doi: 10.1016/j.bioorg.2026.109627

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Ultrafast and Green Encapsulation of Enzymes in Biotitania Nanoparticles via Elastin-like Polypeptide-Mediated Biomimetic Mineralization

Authors: Lin, Yuanqing; He, Yichen; He, Ziyun; Zhan, Weichen; Huang, Yidan; Li, Xue; Cai, Jinzhong; Chen, Lanfang; Xiao, Zushun; Liu, Xingxing; Zhang, Guangya

Journal: ACS Sustainable Chemistry & Engineering

Doi: 10.1021/acssuschemeng.5c12382

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Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates

Authors: Ignacio Relano-Rodriguez, Jianqiu Du, Zi Jie Lin, Margaret Kerwin, Marta Tarquis-Medina, Eduardo Urbano, Jiayan Cui, Meagan Watkins, Christy L Lavine, Peng Zhao, Rumi Habib, Colby Agostino, Sukanya Ghosh, Joyce Park, Caroline Boroughs, Agnes A Walsh, Mariane B Melo, Niharika Shukla, George M Shaw, Beatrice H Hahn, Darrell J Irvine, Lance Wells, David B Weiner, Michael S Seaman, Daniel W Kulp, Ronald S Veazey, Jesper Pallesen, Amelia Escolano

Journal: nature immunology

PubMed ID: 41634485

Doi: 10.1038/s41590-025-02408-z

Expression of IMD-CBM peptide induces the autophagic degradation of CAV1 (caveolin 1) to inhibit LDL transcytosis and retard diabetic atherosclerosis

Authors: Li Wang, Xiong Jia, Xiangli Bai, Ying Zhao, Wenzhuo Cheng, Meng Shu, Yan Shu, Liyin Zhang, Ruonan Wang, Si Jin

Journal: Autophagy

PubMed ID: 41686177

Doi: 10.1080/15548627.2026.2631946