Citations Database

GenScript services and products have been used extensively by scientists worldwide to improve their research efficiency. Here, we have collected a representation of citations for your reference.

Page: 4/536 Results per page

Microbiota-induced T cell plasticity enables immune-mediated tumour control

Authors: Tariq A Najar, Yuan Hao, Yuhan Hao, Gabriela Romero-Meza, Alexandra Dolynuk, Emma Almo, Dan R Littman

Journal: Nature

PubMed ID: 41535459

Doi: 10.1038/s41586-025-09913-z

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TIGIT disruption rescues the antitumor activity of low avidity TCR-engineered T cells by increasing TCR signal strength

Authors: Martina Spiga, Alessia Potenza, Zulma Magnani, Stefano Beretta, Barbara Camisa, Laura Conte, Alessia Airaghi, Neda Mohammadi, Laura Perani, Claudio Doglioni, Maurilio Ponzoni, Francesca Sanvito, Chiara Balestrieri, Lucia Sergi Sergi, Oronza A Botrugno, Giulio Giovannoni, Giovanni Tonon, Danilo Abbati, Chiara Iozzi, Maximilian Reichert, Hana Algul, Arianna Pocaterra, Martina Fiumara, Samuele Ferrari, Alessia Ugolini, Alice Grometto, Giulia Di Lullo, Giovanni Sitia, Giulio Belfiori, Maria Pia Protti, Renato Ostuni, Anna Mondino, Michele Reni, Stefano Crippa, Massimo Falconi, Luigi Naldini, Eliana Ruggiero, Chiara Bonini

Journal: Nature Communications

PubMed ID: 41507193

Doi: 10.1038/s41467-025-67263-w

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Arboviruses manipulate rice’s volatile emissions, protecting insect vectors from natural enemies in the field

Authors: Qing Liu, Qian Wang, Qiong Li, Weiran Wang, Qi Li, Ziyuan Peng, Yuling Jiao, Feng Cui, Ian T Baldwin, Xiaoming Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 41499511

Doi: 10.1126/sciadv.aeb5215

Products & Services: Monoclonal Antibody Services

Cooperativity and communication between the active sites of the dimeric SARS-CoV-2 main protease

Authors: Sarah N Zvornicanin, Ala M Shaqra, Julia Flynn, Lauren E Intravaia, Heidi Carias Martinez, Weiping Jia, Devendra Kumar Gupta, Stephanie Moquin, Dustin Dovala, Daniel N Bolon, Brian A Kelch, Celia A Schiffer, Nese Kurt Yilmaz

Journal: SCIENCE ADVANCES

PubMed ID: 41544157

Doi: 10.1126/sciadv.aeb0769

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FLIPs: Genetically encoded molecular biosensors for functional imaging of cell signaling by linear dichroism microscopy

Authors: Paul Miclea, Vendula Nagy-Marková, Robin Van den Eynde, Wim Vandenberg, Alina Sakhi, Alexey Bondar, Jitka Myšková, Peter Dedecker, Josef Lazar

Journal: SCIENCE ADVANCES

PubMed ID: 41544164

Doi: 10.1126/sciadv.adz5662

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Optimally engineered HLA/peptide-specific CAR-T cells outperform TCR-T cells to eradicate solid tumors

Authors: Corinne E Decker, Jacqueline Idun, Katja Mohrs, Thomas Craig Meagher, Iryna Petriv, Jonathon Golas, Robert Salzler, Timothy Helms, Dharani Ajithdoss, Suhasini Avvaru, Jiaxi Wu, Tong Zhang, Eric Smith, Gavin Thurston, John C Lin, Jessica R Kirshner, David J DiLillo

Journal: SCIENCE ADVANCES

PubMed ID: 41564177

Doi: 10.1126/sciadv.adx9371

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Human cytomegalovirus regulates host DNA repair machinery for viral genome integrity

Authors: Pierce Longmire, Sebastian Zeltzer, Kristen Zarrella, Olivia Daigle, Marek Svoboda, Justin M Reitsma, Scott S Terhune, Carly Bobak, Giovanni Bosco, Felicia Goodrum

Journal: Nucleic Acids Research

PubMed ID: 41533576

Doi: 10.1093/nar/gkaf1445

Products & Services: Protein Electrophoresis and Western

Staufen dsRNA-binding domain as modules to design bifunctional antibodies for siRNA delivery

Authors: Yahui Liu, Yan Zheng, Ruolin Xu, Yanan Quan, Wanyi Tai

Journal: Nucleic Acids Research

PubMed ID: 41569158

Doi: 10.1093/nar/gkaf1539

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All-PEG-Like Block Copolymers Self-Assemble into Stealth Nanocarriers for Drug Delivery

Authors: Parul Sirohi, Brooke E Silverstein, Yulia Shmidov, Sonal Deshpande, Joy Tong, Yvonne Y Ma, Chinmay S Potnis, Soumen Saha, Xinghai Li, Max R Ney, Sarah Y Kim, Joshua J Milligan, Lixin Fan, Matthew L Becker, Daniel Reker, Ashutosh Chilkoti

Journal: Advanced Science

PubMed ID: 41549226

Doi: 10.1002/advs.202517048

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Dyslipidaemia-associated natural IgM improves oncolytic virus TILT-123 efficacy through antibody-dependent enhancement in solid tumours.

Authors: James Hugo Armstrong Clubb, Santeri Artturi Pakola, Sakari Joenväärä, Tatiana Viktorovna Kudling, Tiialotta Tohmola, Victor Arias, Elise Jirovec, Mirte van der Heijden, Dafne Carolina Alves Quixabeira, Annukka Pasanen, Lyna Haybout, Nea Ojala, Saru Basnet, Arianna Eleuteri, Julia Davila Ferrero, Stella Hirvenoja, Inge Marie Svane, Johanna Mäenpää, Katriina Jalkanen, Matthew Stephen Block, Tuomo Alanko, Tine Monberg, Sanae Zahraoui, Susanna Grönberg-Vähä-Koskela, Natasha Salmelin, Claudia Kistler, Riikka Havunen, Suvi Sorsa, João Manuel Dos Santos, Victor Cervera-Carrascon, Anna Kanerva, Otto Hemminki, Risto Renkonen, Akseli Hemminki

Journal: Molecular Therapy

PubMed ID: 41566775

Doi: 10.1016/j.ymthe.2026.01.019

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Genetic engineering of systemically injectable oncolytic viruses for pyroptosis-accelerated cancer virotherapy

Authors: Xiaohong Chen, Minqi Yang, Yuxuan Chen, Yao Zhang, Shuang Wang, Jiaqi Meng, Zunqiao Zhu, Wen Li, Wei Wei, Yuan Ping, Tingbo Liang

Journal: Nature cancer

PubMed ID: 41545714

Doi: 10.1038/s43018-025-01078-y

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Immunoregulatory gene GIMAP6 suppresses lethal atherosclerotic vasculopathy and ischemic heart failure

Authors: Chen Xiang; Kaja Arusha; Danielle Springer; Sachiko Nakamori; Ping Du Jiang; Zhi-Hong Yang; Jing Cui; Yu Zhang; Huie Jing; Ann Y. Park; Maria H. Zhu; Sarah E. Weber; Deniz Cagdas; Hassan Abolhassan; Nasrin Behniafard; Margery G. Smelkinson; Qihui Liang; Elif Everest; Julia F. Kun; Alyssa Grogan; Jennifer D. Treat; Christa S. Zerbe; Steven M. Holland; Renu Virmani; Alan T. Remaley; Helen C. Su; Lixin Zheng; Michael J. Lenardo

Journal: biorxiv

PubMed ID: 41743988

Doi: 10.64898/2026.01.26.701509

Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Authors: Tyler N. Starr; Allison J. Greaney; Cameron M. Stewart; Alexandra C. Walls; William W. Hannon; David Veesler; Jesse D. Bloom; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok

Journal: PLOS Pathogens

PubMed ID: 36399443

Doi: 10.1371/journal.ppat.1010951

Molecular mechanism of ziresovir targeting the fusion glycoprotein of respiratory syncytial virus

Authors: Mengrong Yan; Jingjing Zou; Zhao Gao; Haiqing Yuan; Jim Zhen Wu; Gang Zou; Fengjiang Liu; Wei Peng

Journal: PLOS Pathogens

PubMed ID: 41576151

Doi: 10.1371/journal.ppat.1013864

SARS-CoV-2 Mpro inhibitors from Siphonostegia chinensis : an integrated biophysical and computational study

Authors: Yingjie Ren; Wei Wang; Dai Zhang; Mingliang Zhang; Hui Zhang; Yali Wu; Feiyan Liu; Liuqing Yang; Pan Wang; Lei Chen; Xiaofei Chen; Jinfa Tang; Xianqing Ren

Journal: Frontiers in chemistry

PubMed ID: 42040628

Doi: 10.3389/fchem.2026.1790228

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M pro and cathepsin L

Authors: Michael Dominic Sacco; Chunlong Ma; Panagiotis Lagarias; Ang Gao; Julia Alma Townsend; Xiangzhi Meng; Peter Dube; Xiujun Zhang; Yanmei Hu; Naoya Kitamura; Brett Hurst; Bart Tarbet; Michael Thomas Marty; Antonios Kolocouris; Yan Xiang; Yu Chen; Jun Wang

Journal: biorxiv

PubMed ID: 32766590

Doi: 10.1101/2020.07.27.223727

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Authors: Ting-Syuan Lin; Jingting Wan; Jingjin He; Shidong Cui; Yun Huang; Bojian Zhang; Hsi-Yuan Huang; Kexin Zhu; Jihang Chen; Tao Zhang; Shangfu Li; Liao Hu; Yongfei Wang; Hsien-Da Huang; Ping Tang; Yang-Chi-Dung Lin

Journal: Pharmaceutics

PubMed ID: 41900810

Doi: 10.3390/pharmaceutics18030324

Products & Services: Protein Electrophoresis and Western

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Journal: Pharmaceutics

PubMed ID: 41900810

Doi: 10.3390/pharmaceutics18030324

Products & Services: Protein Electrophoresis and Western

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Journal: Pharmaceutics

PubMed ID: 41900810

Doi: 10.3390/pharmaceutics18030324

Products & Services: Protein Electrophoresis and Western

Enhanced Production of HCV E1E2 Subunit Vaccine Candidates via Protein-Protein Interaction Identification in Glycoengineered CHO cells

Authors: Mina Ying Min Wu; Frances Rocamora; Caressa M. Robinson; Seunghyeon Shin; Eric A. Toth; Thomas R. Fuerst; Svetlana Maurya; Nathan E. Lewis

Journal: biorxiv

PubMed ID: 40475571

Doi: 10.1101/2025.05.20.655202

Protection against lethal canine distemper virus infection by a dual epitope-targeting synthetic antibody

Authors: Melanie Scherer, Nadia Djabeur, Oliver Siering, Jean-Marc Jeckelmann, Marianne Wyss, Marina Cresci, Morgane Di Palma Subran, Rainer Riedl, Patrick Chames, Christian K Pfaller, Bevan Sawatsky, Dimitrios Fotiadis, Philippe Plattet

Journal: Nature Communications

PubMed ID: 41501035

Doi: 10.1038/s41467-025-67600-z

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ERECTA genes and their ligands regulate shoot and inflorescence architecture in maize

Authors: Xiao Liu, Jinbiao Wang, Jipeng Li, Lu Kang, Mengyan Wang, Zhaoyu Huang, Jarrett Man, Xuxu Huang, Zhiming Zhang, Fang Yang, Madelaine Bartlett, Liuji Wu, Zhaobin Dong, David Jackson, Fang Xu

Journal: Nature Communications

PubMed ID: 41526346

Doi: 10.1038/s41467-025-67634-3

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Mechanism of trans-envelope bacterial polysaccharide secretion in Class-3 outer-membrane polysaccharide export (OPX) protein systems

Authors: Abdelkader Mellouk, Kenny Ngo, Ahmad A Kezzo, Cyrielle Martini, Tanos C C França, Steven R Laplante, Salim T Islam, Charles Calmettes

Journal: Nature Communications

PubMed ID: 41545361

Doi: 10.1038/s41467-025-67321-3

Products & Services: Gene Synthesis

Metal ions govern coronavirus endoribonuclease activity

Authors: Xionglue Wang, Jing Li, Zhichao Liu, Longfei Wang, Bin Zhu

Journal: Nucleic Acids Research

PubMed ID: 41533565

Doi: 10.1093/nar/gkaf1508

Products & Services: Codon Optimization

Substituent-Based Modulation of Self-Assembly and Immunogenicity of Amphipathic Peptides

Authors: Anirban Das, Ushasi Pramanik, Elise M Brown, Chih-Yun Liu, Huan Gong, Jonathan Fascetti, Mark Gibson, Samuel Stealey, Silviya P Zustiak, Cory Berkland, Piyoosh Sharma, Meredith E Jackrel, Mark A White, Jai S Rudra

Journal: Advanced Science

PubMed ID: 41560329

Doi: 10.1002/advs.202518567

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Pan2-Pan3 Complex-Mediated Deadenylation Enforces mRNA Quality Control for Infection of the Rice Blast Fungus

Authors: Ziwei Lv, Junting Feng, Shenxian Zhou, Zhiguang Qu, Jun Peng, Xiao-Lin Chen, Deng Chen

Journal: Advanced Science

PubMed ID: 41556236

Doi: 10.1002/advs.202518269

Targeting WTAP/ROR1/WNT5A-Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Authors: Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai

Journal: Advanced Science

PubMed ID: 41562250

Doi: 10.1002/advs.202520661

Products & Services: Protein Electrophoresis and Western

Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammation

Authors: Jun Nagai, Madeline M Hastings, Airi Nishida, Sreyashi Majumdar, Kendall Zaleski, Sofia A Marshall, Junrui Lin, Mira A S Saliman, Yumi Tani, Yamato Murakami, Chunli Feng, Alexander Perniss, Caitlin Wong, Lora G Bankova, Asuka Inoue, Nora A Barrett, Joshua A Boyce

Journal: Cell Reports

PubMed ID: 41422505

Doi: 10.1016/j.celrep.2025.116758

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DUSP22 dephosphorylates LGALS1 to enhance T cell-driven antitumor immunity

Authors: Lijian Wang, Yutong Guo, Yujie Dai, Wangsheng Sun, Xiaoying Huang, Haipeng Lei, Aiping Zhang, Shuwen Chen, Yiting Li, Jiani Pan, Yangjian Hong, Lingchuan Ma, Yangyang Feng, Fangyuan Shao, Jianming Zeng, Peng Luo, Junqi Li, Weiting Chen, Na Zhou, Yang Li, Heng Sun, Xiaoling Xu, Chu-Xia Deng, Kai Miao

Journal: Journal for ImmunoTherapy of Cancer

PubMed ID: 41611244

Doi: 10.1136/jitc-2025-013142

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CATSPERε extracellular domains are essential for sperm calcium channel assembly and activity modulation

Authors: Jae Yeon Hwang, Huafeng Wang, Jong-Nam Oh, Jingon Kim, Sarah F Finnegan, Niels E Skakkebaek, Jean-Ju Chung

Journal: Science advances

PubMed ID: 41604475

Doi: 10.1126/sciadv.adw341

Products & Services: Peptide Synthesis

Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor

Authors: Gang Ye; Fan Bu; Hailey Turner-Hubbard; Morgan Herbst; Lanying Du; Ge Yang; Bin Liu; Fang Li

Journal: Nature

PubMed ID: 41813895

Doi: 10.1038/s41586-026-10240-0

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Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor

Authors: Gang Ye; Fan Bu; Hailey Turner-Hubbard; Morgan Herbst; Lanying Du; Ge Yang; Bin Liu; Fang Li

Journal: Nature

PubMed ID: 41813895

Doi: 10.1038/s41586-026-10240-0

Products & Services: Gene Synthesis

SARS-CoV-2 Mpro inhibitors from Siphonostegia chinensis : an integrated biophysical and computational study

Authors: Yingjie Ren; Wei Wang; Dai Zhang; Mingliang Zhang; Hui Zhang; Yali Wu; Feiyan Liu; Liuqing Yang; Pan Wang; Lei Chen; Xiaofei Chen; Jinfa Tang; Xianqing Ren

Journal: Frontiers in chemistry

PubMed ID: 42040628

Doi: 10.3389/fchem.2026.1790228

SARS-CoV-2 Mpro inhibitors from Siphonostegia chinensis : an integrated biophysical and computational study

Authors: Yingjie Ren; Wei Wang; Dai Zhang; Mingliang Zhang; Hui Zhang; Yali Wu; Feiyan Liu; Liuqing Yang; Pan Wang; Lei Chen; Xiaofei Chen; Jinfa Tang; Xianqing Ren

Journal: Frontiers in chemistry

PubMed ID: 42040628

Doi: 10.3389/fchem.2026.1790228

Cooked meat-derived extracellular vesicles ssc-miR-1 induces metabolic disorders in the mice liver via PI3k/AKT pathway

Authors: Linyuan Shen, Jianfeng Ma, Shuang Liang, Yiting Yang, Tianci Liao, Yuhang Lei, Lei Chen, Yan Wang, Ye Zhao, Lili Niu, Mailin Gan, Li Zhu

Journal: NPJ science of food

PubMed ID: 41577711

Doi: 10.1038/s41538-026-00709-7

Products & Services: Protein Electrophoresis and Western

Structure of the Prenyltransferase in Bifunctional Copalyl Diphosphate Synthase from Penicillium fellutanum Reveals an Open Hexamer Conformation

Authors: Matthew N. Gaynes; Trey A. Ronnebaum; Kollin Schultz; Jacque L. Faylo; Ronen Marmorstein; David W. Christianson

Journal: Journal of structural biology

PubMed ID: 38184156

Doi: 10.1016/j.jsb.2023.108060

Products & Services: Plasmid DNA Preparation

Structure of the Prenyltransferase in Bifunctional Copalyl Diphosphate Synthase from Penicillium fellutanum Reveals an Open Hexamer Conformation

Authors: Matthew N. Gaynes; Trey A. Ronnebaum; Kollin Schultz; Jacque L. Faylo; Ronen Marmorstein; David W. Christianson

Journal: Journal of structural biology

PubMed ID: 38184156

Doi: 10.1016/j.jsb.2023.108060

Products & Services: Plasmid DNA Preparation

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M pro and cathepsin L

Journal: biorxiv

PubMed ID: 32766590

Doi: 10.1101/2020.07.27.223727

Enhanced Production of HCV E1E2 Subunit Vaccine Candidates via Protein-Protein Interaction Identification in Glycoengineered CHO cells

Authors: Mina Ying Min Wu; Frances Rocamora; Caressa M. Robinson; Seunghyeon Shin; Eric A. Toth; Thomas R. Fuerst; Svetlana Maurya; Nathan E. Lewis

Journal: biorxiv

PubMed ID: 40475571

Doi: 10.1101/2025.05.20.655202

A series of pyrimidine-based antifungals with anti-mold activity disrupt ER function in Aspergillus fumigatus

Authors: Martin T. Kelty; Aracely Miron-Ocampo; Sarah R. Beattie

Journal: Microbiology Spectrum

PubMed ID: 38916314

Doi: 10.1128/spectrum.01045-24

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First inhibitor of a bacterial two-partner secretion system

Authors: Alfred Hartojo; Laurence Don Wai Luu; Lachlan Adamson; Kyra Majors; Ashleigh S. Paparella; Peggy A. Cotter; Richard M. Johnson; Matthew Thomas Doyle

Journal: biorxiv

PubMed ID: 41648283

Doi: 10.64898/2026.01.11.698920

Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo

Authors: Yancheng Liu; Shumin Tan; Lu Huang; Robert B. Abramovitch; Kyle H. Rohde; Matthew D. Zimmerman; Chao Chen; V ronique Dartois; Brian C. VanderVen; David G. Russell

Journal: The Journal of experimental medicine

PubMed ID: 27114608

Doi: 10.1084/jem.20151248

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IgG-Bridging–Seeded Synergistic Aggregation of SARS-CoV-2 Spikes Underlies Potent Neutralization by a Low-Affinity Antibody

Authors: Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li-Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

PubMed ID: 41355083

Doi: 10.1002/advs.202517192. Online ahead of print.

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Thermodynamic Profiling Reveals DNA Polymerase Template Binding, Substrate Incorporation, and Exonuclease Function

Authors: Yaping Sun, Wu Lin, Kang Fu, Jie Gao, Xianhui Zhao, Yun He, Hui Tian

Journal: International Journal of Molecular Sciences

Doi: doi.org/10.3390/ijms262411909

Products & Services: Gene Synthesis Plasmid DNA Preparation Protein Electrophoresis and Western CRISPR KI Templates

Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activity

Authors: Christopher R Horne, Tingting Wang, Samuel N Young, Toby A Dite, Hunter G Nyvall, Sushant Suresh, Katherine A Davies, Abner Gonzalez Castro, Vineet Vaibhav, Lucy J Mather, Laura F Dagley, Matthew J Belousoff, Gerard Manning, Anthony R Means, John E Burke, Janni Petersen, John W Scott, James M Murphy

Journal: The Biochemical journal

PubMed ID: 41003242

Doi: doi.org/10.1042/BCJ20253431

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Iterative Epitope Expansion Enables Structure-Guided de novo Design of IgE-Binding Miniproteins Targeting the FcεRI Interface

Authors: Ido Calman, Hamed Shaykhalishahi, Puwanat Sangkhapreecha, Sharrol Bachas

Journal: biorxiv

Doi: 10.64898/2025.12.27.696647

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A Multimodal Ensemble Framework for Optimal Mutant Prediction and Computational Enzyme Engineering

Authors: Ding Luo, Huining Ji, Baodong Hu, Jinxing Cai, Kaiqi Wen, Xiaoyang Qu, Mingfeng Cao, Xinrui Zhao, Binju Wang

Journal: ANGEWANDTE CHEMIE

PubMed ID: 41410226

Doi: 10.1002/anie.202521396

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Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

Authors: Jing Zhang, Xiaoran Lu, Sunan Li, Tao Wang, Iqbal Ahmad, Yong-Hui Zheng

Journal: Advanced Science

PubMed ID: 41324484

Doi: 10.1002/advs.202519256

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U-Shaped Response of Flowering Time to Low and High Nitrogen via a Transcription Feedback Loop in Rice

Authors: Shunan Zhang, Guanzhong Shou, Xianping Li, Xuemin Song, Xuesong Li, Junjie Guo, Jiaqiang Lu, Yi Jin, Hongye Qu, Ming Yan, Wona Ding, Ying Liu, Guohua Xu

Journal: Advanced Science

PubMed ID: 41354635

Doi: 10.1002/advs.202508498

Tuning CAR-T cells by targeting cancer-associated glycan in pancreatic cancer

Authors: Sangwoo Park, Cassidy E Ho, Eli P Darnell, Alexandra N Wolff, Hana Takei, Filippo Birocchi, Amanda A Bouffard, Diego Salas-Benito, Giulia Escobar, Mark B Leick, Adele Mucci, Trisha R Berger, Marcela V Maus

Journal: Nature Communications

PubMed ID: 41372740

Doi: 10.1038/s41467-025-66102-2

A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription

Authors: Anna Minello, Jesus Gomez-Escudero, Sreerama Chaitanya Sridhara, Charlotte Martin, Elodie Girard, Juan C Cañas, Yasin Memari, Maria Rose Bustos, Antonio Galarreta, Virginie Boucherit, Evgeny Imyanitov, Sigridur Klara Bodvarsdottir, Sylvain Baulande, Anne Vincent-Salomon, Nicolas Servant, Matthias Altmeyer, Stefan Sigurdsson, Dominique Stoppa-Lyonnet, Serena Nik-Zainal, Aura Carreira

Journal: Nature Communications

PubMed ID: 41372141

Doi: 10.1038/s41467-025-67209-2

Products & Services: Polyclonal Antibody Services

HYPK promotes N-terminal protein acetylation through rapid ribosome exchange of NatA

Authors: Alfred M Lentzsch, Ziyi Fan, Inayat U Irshad, Edward P O'Brien, Ajeet K Sharma, Rachel Green, Shu-Ou Shan

Journal: Molecular Cell

PubMed ID: 41380682

Doi: 10.1016/j.molcel.2025.11.017

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Collision-induced ribosome degradation driven by ribosome competition and translational perturbations

Authors: Sihan Li, Okuto Shounai, Misaki Kato, Ken Ikeuchi, Toshifumi Inada

Journal: Nature Communications

PubMed ID: 41387539

Doi: 10.1038/s41467-025-66026-x

Products & Services: Peptide Synthesis

Gut Microbe-Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Authors: Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao

Journal: Advanced Science

PubMed ID: 41386783

Doi: 10.1002/advs.202520326

Products & Services: Protein Electrophoresis and Western

Engineering HLA-G-targeted extracellular vesicles nanoplatform for enhanced cancer therapy through precise cancer drug delivery

Authors: Ming-You Shie, Shi-Wei Huang, Yeh Chen, Mei-Chih Chen, Chih-Ming Pan, Cheng-Yu Chen, Yen-Hong Lin, Min-Hua Yu, Kai-Wen Kan, Shao-Chih Chiu, Hui-Chun Ho, Yi-Wen Chen, Der-Yang Cho

Journal: Nature Communications

PubMed ID: 41390497

Doi: 10.1038/s41467-025-66451-y

Targeting Protein Protein Interactions (PPIs) to Drive Functional Annotation: An Integrative Methodology to Study Senescence-Associated PPIs Using TMPRSS11a as Model Interactor

Authors: Roberto Rosales-Rojas; Christian Fern ndez; Mariela Gonz lez-Avenda o; Ariela Vergara-Jaque; M nica C ceres

Journal: Biomolecules

PubMed ID: 42194062

Doi: 10.3390/biom16050714

Targeting Protein Protein Interactions (PPIs) to Drive Functional Annotation: An Integrative Methodology to Study Senescence-Associated PPIs Using TMPRSS11a as Model Interactor

Authors: Roberto Rosales-Rojas; Christian Fern ndez; Mariela Gonz lez-Avenda o; Ariela Vergara-Jaque; M nica C ceres

Journal: Biomolecules

PubMed ID: 42194062

Doi: 10.3390/biom16050714

Cynarin as a potent anti‑osteolytic agent: Targeting MAPK and Nrf2‑Keap1 pathways for osteoclast inhibition and bone protection

Authors: Rui Chao, Yexin Wang, Zhan Liu, Tianhao Wan, Yi Mao, Xinru Xie, Lei Sun, Weifeng Xu, Xuzhuo Chen, Shanyong Zhang

Journal: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PubMed ID: PMC12488209

Doi: 10.3892/ijmm.2025.5647

Products & Services: Protein and Antibody Isolation

Excessive vigorous exercise impairs cognitive function through a muscle-derived mitochondrial pretender

Authors: Yan Huang, Biao Hu, Ya Liu, Ling-Qi Xie, Yu Dai, Yu-Ze An, Xin-Yi Peng, Ya-Lun Cheng, Yi-Fan Guo, Wei-Hong Kuang, Yao Xiao, Xin Chen, Yong-Jun Zheng, Gen-Qing Xie, Jian-Ping Wang, Hui Peng, Xiang-Hang Luo

Journal: Cell metabolism

PubMed ID: 41344322

Doi: doi.org/10.1016/j.cmet.2025.11.002

Products & Services: Nucleic Acid Purification

RING- Type E3 Ligase OsRFPH2- 6 Ubiquitinates Nuclear Factor Y Subunit OsNF- YA1 to Suppress Rice Immunity

Authors: Yan Bi, Leeza Tariq, Hui Wang, Yuqing Yan, Dayong Li, Fengming Song

Journal: Molecular plant pathology

PubMed ID: 41424058

Doi: 10.1111/mpp.70193

Products & Services: Catalog Antibodies

The Human T-cell Leukemia Virus capsid protein is a potential drug target

Authors: Ruijie Yu, Prabhjeet Phalora, Nan Li, Till Böcking, David Anthony Jacques

Journal: Nature Communications

PubMed ID: 41345105

Doi: 10.1038/s41467-025-65899-2

Structure-Based Development of Ultra-Broad-Spectrum 3C-Like Protease Inhibitors

Authors: Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu

Journal: Advanced Science

PubMed ID: 41388583

Doi: 10.1002/advs.202512342

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Protein-nucleic acid language model-assisted design of precise and compact adenine base editor

Authors: Jingxuan Ren, Jiawei Yao, Qiuyu Cao, Yinuo Li, Yang Li, Ziyi Zhang, Xiyu Ge, Shengfang Wang, Yang Zhang, Xiaogang Wang, Xiaohui Zhang

Journal: Nature Communications

PubMed ID: 41390734

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Organ-specific delivery of an mRNA-encoded bispecific T cell engager targeting glypican-3 in hepatocellular carcinoma

Authors: Yan Huang, Shaoli Liu, Xiaoju Zhang, Bingxu Zhang, Feng Shi, Jia Zhang, Shuaibo Shao, Hongya Han, Xiaoyun Ma, Jing Xie, Jianqi Zhang, Hongxiaoying Yu, Yongchao Zhao, Jiazheng Jin, Dong Xu, Liang Liu, Jianing Wang, Yu Tan, Kelu Xu, Lushuai Jin, Quanjun Du, Yifeng Geng, Andong Liu, Wei Xu

Journal: Nature Communications

PubMed ID: 41397962

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Molecular insights into ligand recognition and signaling of OXGR1

Authors: Aijun Liu, Yezhou Liu, Yuanzhengyang Long, Richard D Ye

Journal: Nature Communications

PubMed ID: 41413034

Doi: 10.1038/s41467-025-67101-z

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Semi-inductive dataset construction and framework optimization for practical drug target interaction prediction with ScopeDTI

Authors: Yigang Chen; Xiang Ji; Ziyue Zhang; Zihao Zhu; Yuming Zhou; Chang Su; Yang-Chi-Dung Lin; Hsi-Yuan Huang; Kangping Wei; Yi Lai; Ke Chen; Xingqiao Lin; Yangyi Zhang; Jiehui Fu; Yixian Huang; Shidong Cui; Shih-Chung Yen; Tao Zhang; Arieh Warshel; Hsien-Da Huang

Journal: Nature Communications

PubMed ID: 41390462

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Structural basis of Neisseria meningitidis quinol dependent nitric oxide reductase activation by dimerization

Authors: Chai C. Gopalasingam; Haruka Egami; Hideki Shigematsu; Masatora Sakaue; Kouki Fukumoto; Christoph Gerle; Masaki Yamamoto; Yoshitsugu Shiro; Kazumasa Muramoto; Takehiko Tosha

Journal: Communications Biology

PubMed ID: 41896389

Doi: 10.1038/s42003-026-09754-0

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From Multi-Species Screening to Targeted Investigation: Discovery of ACE Inhibitory Peptides in Gigantidas platifrons via Peptidomics, Virtual Screening, and Molecular Dynamics Simulations

Authors: Haorui Zhang; Yuhong Ouyang; Qishan Suo; Hao Chen; Jie Cui; Yang Yue

Journal: Molecules

PubMed ID: 41828750

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Nuclear effects play an important role in determining codon usage-dependent human gene expression

Authors: Renu Garg, Pancheng Xie, Jiabin Duan, Huan Liu, Yi Liu

Journal: Nature Communications

PubMed ID: 41339630

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Structural basis of microtubule-mediated signal transduction

Authors: Sung Ryul Choi, Thorsten B Blum, Matteo Giono, Bibhas Roy, Ioannis Vakonakis, Dominic Schmid, Nicole Oelgarth, Apisha Ranganathan, Alvar D Gossert, G V Shivashankar, Alfred Zippelius, Michel O Steinmetz

Journal: Cell

PubMed ID: 41365297

Doi: 10.1016/j.cell.2025.11.011

Personalized CRISPR knock-in cytokine gene therapy to remodel the tumor microenvironment and enhance CAR T cell therapy in solid tumors

Authors: Michael Launspach, Julia Macos, Shoaib Afzal, Janik Hohmann, Marc L Appis, Maximilian Pilgram, Stefanie Beez, Emily Ohlendorf, Casper F T van der Ven, Chahrazad Lachiheb, Karin Töws, Lena Andersch, Marvin Jens, Felix Zirngibl, Jonas Kath, Maria Stecklum, Elias Rodriguez-Fos, Kathleen Anders, Dimitrios L Wagner, Anton G Henssen, Ralf Kühn, Angelika Eggert, Annette Künkele

Journal: Nature Communications

PubMed ID: 41366257

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A highly active Burkholderia polyketoacyl-CoA thiolase for production of triacetic acid lactone

Authors: Zilong Wang, Seokjung Cheong, Jose Henrique Pereira, Weixi Hu, Yifan Guo, Andy DeGiovanni, Guangxu Lan, Jinho Kim, Robert W Haushalter, Taek Soon Lee, Paul D Adams, Jay D Keasling

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PubMed ID: 41365852

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Geminin inhibits DNA replication licensing by sterically blocking CDT1-MCM2 interactions

Authors: Joshua Tomkins, Lucy V Edwardes, Sarah V Faull, Matthew Peach, Peter J Gillespie, Vera Leber, Anna Schmidt, Halil Bounoua, Nicholas Sim, Rosa Camarillo, J Julian Blow, Alexis R Barr, Anna Barnard, Christian Speck

Journal: Nature Communications

PubMed ID: 41365879

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Induced Proprioceptor and Low-Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties

Authors: Amy J Hulme, Rocio K Finol-Urdaneta, Jeffrey R McArthur, Nicholas R Marzano, Simon Maksour, Amarinder Thind, Yang Guo, Dominic Kaul, Marnie Maddock, Oliver Friedrich, Boris Martinac, David J Adams, Mirella Dottori

Journal: Advanced Science

PubMed ID: 41364594

Doi: 10.1002/advs.202512413

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TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

Authors: Maria G Herrera, Lena Kühn, Lisa Jungbluth, Verian Bader, Laura J Krause, David Kartte, Elias Adriaenssens, Sascha Martens, Jörg Tatzelt, Carsten Sachse, Konstanze F Winklhofer

Journal: Advanced Science

PubMed ID: 41405403

Doi: 10.1002/advs.202509927

Nuclear speckle proteins form intrinsic and MALAT1-dependent microphases

Authors: Min Kyung Shinn, Dylan T Tomares, Vicky Liu, Avnika Pant, Yuanxin Qiu, Andreas Vitalis, You Jin Song, Yuna Ayala, Kiersten M Ruff, Gregory W Strout, Matthew D Lew, Kannanganattu V Prasanth, Rohit V Pappu

Journal: Cell

PubMed ID: 41421357

Doi: 10.1016/j.cell.2025.11.026

Synthesis of Bispecific Conjugates by ADP-Ribosyl Cyclases

Authors: Sunny H Kim, Arshad J Ansari, Lei Zhang, Guoyun Kao, Thuc Oanh Hoang, Zeyu Zhang, Srinivasarao Singireddi, Benjamin B Katz, Yong Zhang

Journal: Advanced Science

PubMed ID: 41422434

Doi: 10.1002/advs.202518329

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A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Authors: Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S L Parker, Yingying Guo, Dongming Zhou

Journal: Advanced Science

PubMed ID: 41431149

Doi: 10.1002/advs.202512262

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ApoE2-DARPin fusion proteins enable selective RNA transfer to CD8 T cells by lipid nanoparticles

Authors: Samuel A Theuerkauf, Luca J Zinser, Nandini Sheth, Elham Adabi, Lea R Knapp, Johanna M Gorol, Sascha Hein, Angeliki Chroni, Frederic B Thalheimer, Christian J Buchholz

Journal: Journal of controlled release

PubMed ID: 41197834

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Supramolecular lipid nanoparticle reprograms tumor microenvironment by cucurbit[7]uril-based host–guest recognition for STING-activating cancer immunotherapy

Authors: Yunxuan Feng, Yuan Yu, Xinyang Yu, Mengyao Li, Jiaqi Lei, Yongcan Li, Zhida Liu, Shaolong Qi, Guocan Yu

Journal: Materials Today

Doi: doi.org/10.1016/j.mattod.2025.11.029

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OMP16-targeting monoclonal antibodies H4 and E6 reveal essential linear epitopes for Brucella immunoprotection

Authors: Yunyi Zhai, Kaihui Sun, Ye Yuan, Xiaofang Liu, Gaowa Wudong, Yuanhao Yang, Shuan Qu, Yaxin Li, Dong Zhou, Wei Liu, Yaping Jin, Aihua Wang

Journal: International Journal of Biological Macromolecules

PubMed ID: 41448303

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Study on the phosphorylation of NAD+-specific isocitrate dehydrogenase in the pathogenic bacteria Stenotrophomonas maltophilia and Xanthomonas sacchari

Authors: Qian Tian, Yongmei Zhang, Chunxu Pan, Linxiao Wang, Na Qin, Zhen Jiang, Chenxi Li, Zhengyu Cao, Guoping Zhu, Peng Wang

Journal: Journal of enzyme inhibition and medicinal chemistry

PubMed ID: 41395810

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The ATPase activity of ABCB10 is modulated by conserved transmembrane arginine residues and by functional groups in the biliverdin molecule

Authors: Annabella Nouel Barreto, Valeria Arellano Haro, Alex L Hernandez, Maria E Zoghbi

Journal: Protein Science

PubMed ID: 41229075

Doi: 10.1002/pro.70366

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Design of precision therapeutics for a CKD risk allele by targeting Shroom3-Rock interaction

Authors: Anand Reghuvaran; Ashwani Kumar; Qisheng Lin; Nallakandi Rajeevan; Khadija Banu; Zeguo Sun; Hongmei Shi; Gabriel Barsotti; EM Tanvir; John Pell; Sudhir Perincheri; Chengguo Wei; Bhavya Bharathan; Marina Planoutene; Anne Eichmann; Valeria Mas; Weijia Zhang; Lloyd G. Cantley; Leyuan Xu; Bhaskar Das; John Cijiang He; Madhav C. Menon

Journal: Nature Communications

PubMed ID: 41469391

Doi: 10.1038/s41467-025-67854-7

Structural basis of Neisseria meningitidis quinol dependent nitric oxide reductase activation by dimerization

Authors: Chai C. Gopalasingam; Haruka Egami; Hideki Shigematsu; Masatora Sakaue; Kouki Fukumoto; Christoph Gerle; Masaki Yamamoto; Yoshitsugu Shiro; Kazumasa Muramoto; Takehiko Tosha

Journal: Communications Biology

PubMed ID: 41896389

Doi: 10.1038/s42003-026-09754-0

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First inhibitor of a bacterial two-partner secretion system

Authors: Alfred Hartojo; Laurence Don Wai Luu; Lachlan Adamson; Kyra Majors; Ashleigh S. Paparella; Peggy A. Cotter; Richard M. Johnson; Matthew Thomas Doyle

Journal: biorxiv

PubMed ID: 41648283

Doi: 10.64898/2026.01.11.698920

Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo

Authors: Yancheng Liu; Shumin Tan; Lu Huang; Robert B. Abramovitch; Kyle H. Rohde; Matthew D. Zimmerman; Chao Chen; V ronique Dartois; Brian C. VanderVen; David G. Russell

Journal: The Journal of experimental medicine

PubMed ID: 27114608

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Targeting Protein Protein Interactions (PPIs) to Drive Functional Annotation: An Integrative Methodology to Study Senescence-Associated PPIs Using TMPRSS11a as Model Interactor

Authors: Roberto Rosales-Rojas; Christian Fern ndez; Mariela Gonz lez-Avenda o; Ariela Vergara-Jaque; M nica C ceres

Journal: Biomolecules

PubMed ID: 42194062

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Acyl-CoA-binding protein AcbdA is required for peroxisome hitchhiking on early endosomes in Aspergillus nidulans

Authors: Bellana E Driscoll, Madison B Fountain, Isabella N Gates, Reihane Abdollahi, Allison M Langley, Matthew B Owens, Jenna R Christensen, John Salogiannis

Journal: Molecular biology of the cell

PubMed ID: 40901736

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Molecular mechanism of PINK1 regulation by the Hsp90 machinery

Authors: Xuyang Tian, Jiayue Su, Ziyi Wang, Tao Liu, Huifang Xiong, Shan Sun, Kunrong Mei, Sen-Fang Sui

Journal: Nature Communications

PubMed ID: 41326378

Doi: 10.1038/s41467-025-65859-w.

PolySUMOylation of PCNA and Rad52 restricts centromeric recombination in fission yeast

Authors: Katarzyna Markowska, Ireneusz Litwin, Dorota Misiorna, Julia Kończak, Aleksandra Bogdańska, Paulina Tomaszewska, Michał Tracz, Mika Haenen, Karol Kramarz

Journal: Nature Communications

PubMed ID: 41330900

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Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies

Authors: Claudia V Perez Almeria, Omolade Otun, Roman Schlimgen, Thomas D Lamme, Lotte Di Niro, Caitrin Crudden, Jan Paul Bebelman, Noureldine Youssef, Lejla Musli, Shawn Jenjak, Vladimir Bobkov, Julia Drube, Carsten Hoffmann, Brian F Volkman, Sébastien Granier, Cherine Bechara, Marco Siderius, Raimond Heukers, Christopher T Schafer, Martine J Smit

Journal: Nature Communications

PubMed ID: 41330916

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A bypass gateway from cholesterol to sex steroid biosynthesis circumnavigates CYP17A1

Authors: Ziqi Zhu, Yoon-Mi Chung, Mohammad Alyamani, Yijing Dai, Kevin D McCarty, Evan Roberts, Sunita Sinha, Jianneng Li, Xiuxiu Li, Emad M Gad, Zhiqun Zhou, Jinyuan Shi, Robert A Burgess, Tatiana Y Hargrove, Galina I Lepesheva, F Peter Guengerich, Richard J Auchus, Nima Sharifi

Journal: Nature Communications

PubMed ID: 41345099

Doi: 10.1038/s41467-025-66558-2

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β-sheet stabilization of the island domain underlies ligand-induced LRR-RP activation of plant immune signaling

Authors: Simon Snoeck, Lisha Zhang, Valentin Studer, Gijeong Kim, Álvaro D Fernández-Fernández, Thorsten Nürnberger, Cyril Zipfel

Journal: Nature Communications

PubMed ID: 41361182

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Diet-induced RKIP downregulation disrupts PC/PE-ER homeostasis to drive MASLD

Authors: Mengjie Li, Qian Ou, Qiang Qin, Jiaxi Chen, Sen Yang, Jie Zhao, Hua Meng, Xu Li, Pinglong Xu, Cunqi Ye, Xiaojian Wang

Journal: Nature Communications

PubMed ID: 41387436

Doi: 10.1038/s41467-025-65982-8

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Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

Authors: Diana Castaño, Emily Bettini, Binod Kumar, Aleksey Chudnovskiy, Anna Siv, Giulia Protti, Sandra Nakadakari-Higa, Simona Ceglia, Nina De Luna, Joy E Chiu, Katlyn Lederer, Shuk Hang Li, Hassaan Ibrahim, Hiromi Muramatsu, Thandiswa Mdluli, Edit Abraham, Sinem E Sahingur, Ivan Maillard, Ying K Tam, Sunny Shin, Scott E Hensley, Jonathan J Miner, Zoltan Lipinszki, Andrea Reboldi, Norbert Pardi, Roberto Spreafico, Gabriel D Victora, Michela Locci

Journal: Cell

PubMed ID: 41406961

Doi: 10.1016/j.cell.2025.11.023

The resting and ligand-bound states of the membrane-embedded human T-cell receptor–CD3 complex

Authors: Ryan Q Notti, Fei Yi, Søren Heissel, Martin W Bush, Zaki Molvi, Pujita Das, Henrik Molina, Christopher A Klebanoff, Thomas Walz

Journal: Nature Communications

PubMed ID: 41402338

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A genome-wide CRISPR screen identifies GRA38 as a key regulator of lipid homeostasis during Toxoplasma gondii adaptation to lipid-rich conditions

Authors: Mebratu A Bitew, Tatiana C Paredes-Santos, Parag Maru, Shruthi Krishnamurthy, Yifan Wang, Lamba O Sangaré, Samuel Duley, Yoshiki Yamaryo-Botté, Cyrille Y Botté, Jeroen P J Saeij

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PubMed ID: 41407671

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Engineered ipilimumab variants that bind human and mouse CTLA-4

Authors: Brett Robison 1, S J Diong 1, Anusha Kumar 1, Thomas M Moon , Olin Chang , Bryant Chau , Christine Bee , Ishita Barman , Arvind Rajpal , Alan J Korman , Sean West , Pavel Strop , Peter S Lee

Journal: MAbs

PubMed ID: 39849917

Doi: 10.1080/19420862.2025.2451296

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The prion-like characteristic of ORF3 contributes to virion release and pathogenesis of hepatitis E virus

Authors: Yajing Wang, Houlu Tian, Na Shi, Chunyan Wu, Yaowei Huang, Yongling Yang, Qiang Ding, Xu Zheng, Qin Zhao, Zhaonong Hu, Jiaojiao Luo, Lele Feng, Lingdong Xu, Mick F Tuite, Hongying Chen, Yuchen Nan

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41343667

Doi: 10.1073/pnas.2511801122

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