Citations Database

GenScript services and products have been used extensively by scientists worldwide to improve their research efficiency. Here, we have collected a representation of citations for your reference.

Page: 3/536 Results per page

CD3ɛ Nanobody-Engineered Extracellular Vesicles Driving In Vivo Generation of BiTE-Secreting CAR-Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

Authors: Shi-Wei Huang, Yu-Chuan Lin, Chih-Ming Pan, Yeh Chen, Ming-You Shie, Cheng-Yu Chen, Kai-Wen Kan, Yi-Wen Chen, Ming-Chao Liu, Chung-Chun Wu, Yu-Ting Chiang, Huai-Ping Ho, Chen-Yu Lin, Pei-Ying Lin, Yu-Han Huang, Steffany Rusli, Wan-Yu Mao, Pei-Wen Huang, Sin-Ting Wang, Wan-Chen Tsai, Ya-Hsu Chiu, Ting-Hsun Lin, Wan-Ling Chiang, Che-Kai Chang, Zi-Lun Lai, Mei-Chih Chen, Shao-Chih Chiu, Der-Yang Cho

Journal: Advanced Science

PubMed ID: 41632088

Doi: 10.1002/advs.202519440

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

Authors: Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue

Journal: Advanced Science

PubMed ID: 41637534

Doi: 10.1002/advs.202505240

Products & Services: Protein Electrophoresis and Western

Engineering New-to-Nature Biological Pathways for β,γ-Alkanediol Synthesis

Authors: Haofeng Chen, Haidong Yu, Dongjiang Lin, Guojun Yang, Yuchen Xie, Yang Zhang, Jifeng Yuan

Journal: Advanced Science

PubMed ID: 41677379

Doi: 10.1002/advs.202519742

Human DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation

Authors: Natália C Moreno, Emilie J Korchak, Marcela T Latancia, Dana A D'Orlando, Temidayo Adegbenro, Ryan P Barnes, Irina Bezsonova, Roger Woodgate, Nicholas W Ashton

Journal: Nucleic Acids Research

PubMed ID: 41693564

Doi: 10.1093/nar/gkag098

PolyP inhibits CobB deacetylase triggering a regulatory coupling to prevent DNA replication initiation

Authors: Ewelina Boguszewska, Zuzanna Hirsz, Magdalena Sroka, Katarzyna Bury, Weronika Chmura, Agnieszka Strzałka, Marta Kołodziej, Jolanta Zakrzewska-Czerwińska, Igor Konieczny

Journal: Nucleic Acids Research

PubMed ID: 41728951

Doi: 10.1093/nar/gkag144

Characterization of gRNA-dependent and gRNA-independent off-target binding sites of PspCas13b and RfxCas13d in mammalian cells

Authors: Huanhuan Feng, Zhixue Li, Hongdao Zhang, Yuli Zheng, Beiying Xu, Yao Zhang, Lin Zou, Ligang Wu

Journal: Nucleic Acids Research

PubMed ID: 41728952

Doi: 10.1093/nar/gkag112

KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors

Authors: Huimin Shao, Fei Xu, Jiangyue Xu, Lingjie Zhou, Yao Wu, Lianjun He, Xueyi Qian, Weijie He, Nanlin Jiao, Yabin Xia, Jun Zhao, Lili Sheng, Guoliang Mao, Tao Ma, Wei Wang, Shaoxiang Luo, Li Fu, Zhenyu Xu

Journal: SCIENCE ADVANCES

PubMed ID: 41719389

Doi: 10.1126/sciadv.aea2511

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Quantitative genetics of natural S. cerevisiae strains upon mating reveal heritable determinants of fitness and differential mating affinities

Authors: Sivan Kaminski Strauss, Ruthie Golomb, Donya Khoury, Noa Aharon-Hefetz, Hadar Meyer, Dayag Sheykhkarimli, Gianni Liti, Orna Dahan, Yitzhak Pilpel

Journal: Molecular Therapy

PubMed ID: 41689801

Doi: 10.1016/j.celrep.2026.116972

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Functional characterization of secreted Schistosoma mansoni serpin SmSPI reveals Factor XIIa inhibition as evidenced by biochemical, and human plasma assays and supported by AI-assisted structural modelling

Authors: Lukáš Konečný, Kristýna Peterková, Ingrid Hrachovinová, Alex Loukas, Tomáš Macháček, Jan Dvořák, Lucie Jedličková

Journal: Molecular Therapy

PubMed ID: 41724421

Doi: 10.1016/j.ijpara.2026.104808

Identifying microbial protease allergens through protein language model-guided homology

Authors: Kumar Thurimella, Elena Wu, Chenhao Li, Daniel B Graham, Róisín M Owens, Damian R Plichta, Caroline L Sokol, Ramnik J Xavier, Sergio Bacallado

Journal: Molecular Therapy

PubMed ID: 41722567

Doi: 10.1016/j.cels.2025.101510

Messenger RNA delivery to islet β cells using conjugated lipid nanoparticles

Authors: Jacob R Enriquez, Zhengjie Zhou, Jennifer B Nelson, Fei Huang, Kayla T Figatner, Advaita Chakraborty, Sarida Pratuangtham, Brian Xi, Sarah C May, Matthew V Tirrell, Sarah A Tersey, Yun Fang, Raghavendra G Mirmira

Journal: Molecular Therapy

PubMed ID: 41722565

Doi: 10.1016/j.xcrm.2026.102634

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Identification of xenobiotics interfering with 5α-reductase (SRD5A2) activity

Authors: Jacek Kędzierski, Rianne E van Diest, Julien A Allard, Andreas M Erharter, Alex Odermatt, Martin Smieko

Journal: Molecular Therapy

PubMed ID: 41722875

Doi: 10.1016/j.toxlet.2026.111859

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Targeting Langerhans cells using a modular mannosylated nucleic acid-based vaccine platform

Authors: Simon Christian Vinther, Antonia Resag, Karina Thao Thu Le, Claudia Christine Zelle-Rieser, Helen Strandt, Mette Galsgaard Malle, Stig Hill Christiansen, Barbara Del Frari, Theresia Stigger, Bastian Schilling, Jonas Wohlfarth, Steffen Thiel, Julián Valero, Patrizia Stoitzner, Jørgen Kjems

Journal: Molecular Therapy

PubMed ID: 41713595

Doi: 10.1016/j.jconrel.2026.114741

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The protein phosphatase 2A-B56α complex regulates N-Myc degradation in neuroblastoma

Authors: Brian D Tran, Irene Peris, Ethan Wurman, Averie Huang, Gabrielle Hodges Onishi, Jiang Hu, Rita A Avelar, Erika A Newman, Analisa DiFeo, Caitlin M O'Connor, Goutham Narla

Journal: Molecular Therapy

PubMed ID: 41707997

Doi: 10.1016/j.jbc.2026.111298

Heterologous vs. homologous vaccine regimens: Sulfated lactosyl archaeol (SLA) archaeosome-adjuvanted SARS-CoV-2 spike protein boost following an mRNA/LNP prime induces robust and balanced immune responses

Authors: Tyler M Renner, Gerard Agbayani, Hiva Azizi, Lise Deschatelets, Renu Dudani, Blair A Harrison, Usha D Hemraz, Roger Koukiekolo, Matthew Stuible, Yves Durocher, Michael J McCluskie, Bassel Akache

Journal: Vaccine

PubMed ID: 41505874

Doi: 10.1016/j.vaccine.2025.128182

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High-yield production of hydroxytyrosol through metabolic engineering of Yarrowia lipolytica

Authors: Bihuan Chen, Yuanyuan Wang, Danlin Wang, Yina Wang, Xiangyu Liu, Guanghui Zhang, Shengchao Yang

Journal: Synthetic and systems biotechnology

PubMed ID: 41766957

Doi: 10.1016/j.synbio.2026.01.022

Products & Services: Gene Synthesis Codon Optimization

Abstract Supplement Abstracts from AIDS 2022 the 24th International AIDS Conference, 29 July 2 August 2022, Montr al, Canada & Virtual

Authors:

Journal: Journal of the International AIDS Society

PubMed ID: 35916394

Doi: 10.1002/jia2.25935

Humanization and engineering of protective antibodies targeting severe fever with thrombocytopenia syndrome virus Gn protein

Authors: Xuanxiu Ren, Wei Deng, Feiyang Yu, Wenhua Kuang, Heya Na, Shangyu Yang, Jiawen Sun, Jianlun Xu, Bo Shu, Sheng Cao, Xianliang Ke, Zengqin Deng, Yun-Jia Ning, Haiyan Zhao

Journal: Cell Reports

PubMed ID: 41671090

Doi: 10.1016/j.celrep.2026.116936

Products & Services: Protein and Antibody Isolation

Antifibrotic drug finerenone restores fertility in premature ovarian insufficiency

Authors: Zexiong Lin, Yuan Li, Yu Zhao, Dongteng Liu, Shuzi Deng, Jingkai Gu, Yanyan Li, Xudong Zhao, Peishan Wu, Yuan Xiao, Jiaping Su, Yiting Sun, Yihui Zhang, Yin Lau Lee, Yorino Sato, Haitao Zeng, Haonan Lu, Juanhui Zhang, Jennifer K Y Ko, Jing Zhao, Kazuhiro Kawamura, Ernest H Y Ng, Shanfang Jiang, Yu Li, Xi Xia, Karen K L Chan, William S B Yeung, Tianren R Wang, Kui Liu

Journal: Science

PubMed ID: 41643022

Doi: 10.1126/science.adz4075

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Safe and Highly Efficient Lipid-Pro-Dexamethasone Nanoparticles for mRNA Delivery and Base Editing

Authors: Yan Zong, Haiping Zhong, Yuqing Wang, Yi Lin, Linxi Zhao, Xiaoyu Wang, Jianan Cai, Haoyang Lin, Yixi Xiao, Tuo Wei, Shutao Guo, Qiang Cheng

Journal: Journal of the American Chemical Society

PubMed ID: 41733506

Doi: 10.1021/jacs.6c01708

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A histone methylation reader suppresses both disease resistance and tillering by facilitating H3K9me1-mediated gene silencing in rice

Authors: Fengfeng Fan, Manman Liu, Huanran Yuan, Nannan Li, Mingxing Cheng, Xiong Luo, Yu Guo, Ayaz Ahmad, Meng Cai, Fengfeng Si, Zihan Yang, Man Wang, Xiangsong Chen, Kun Wang, Chengcai Chu, Shaoqing Li

Journal: Molecular Plant

PubMed ID: 41408748

Doi: 10.1016/j.molp.2025.12.015

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Genome position does not impact transgene expression efficiency in the ancient red alga Cyanidioschyzon merolae

Authors: Kaian Teles, Gordon B Wellman, Yuhan Zhang, Bárbara Bastos de Freitas, Viktor A Slat, Martha R Stark, Lecong Zhou, Perry J Blackshear, Stephen D Rader, Kyle J Lauersen

Journal: bioRXIV

PubMed ID: 41659391

Doi: 10.1016/j.nbt.2026.05.004

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Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Authors: Tyler N. Starr; Allison J. Greaney; Cameron M. Stewart; Alexandra C. Walls; William W. Hannon; David Veesler; Jesse D. Bloom; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok

Journal: PLOS Pathogens

PubMed ID: 36399443

Doi: 10.1371/journal.ppat.1010951

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Authors: Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo

Journal: Advanced Science

PubMed ID: 41521460

Doi: 10.1002/advs.202515724

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Structural basis for the subtype-selectivity of KCa2.2 channel activators

Authors: Young-Woo Nam, Alena Ramanishka, Yang Xu, Rose Marie Haynes Yasuda, Joshua A Nasburg, Dohyun Im, Meng Cui, K George Chandy, Heike Wulff, Miao Zhang

Journal: Nature Communications

PubMed ID: 41507196

Doi: 10.1038/s41467-025-67232-3

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Engineered outer membrane vesicles enhance solid tumour CAR-T cell therapy

Authors: Xianjun Li, Xuehan Li, Jiaqi Shi, Yingjing Li, Hanyu Zhang, Tianjun Chen, Hui Pang, Shuyuan Zhang, Shengnan Luo, Fengyi Liu, Shuang Li, Chujie Ding, Linlin Sun, Fan Xing, Tongsen Zheng

Journal: Nature biomedical engineering

PubMed ID: 41501251

Doi: 10.1038/s41551-025-01575-6

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A disulfide redox switch mechanism regulates glycoside hydrolase function

Authors: Marcele Pandeló Martins, Gustavo Henrique Martins, Felipe Jun Fuzita, João Paulo Menezes Spadeto, Renan Yuji Miyamoto, Felippe Mariano Colombari, Fabiane Stoffel, Luciano Graciani Dolce, Camila Ramos Dos Santos, Rodrigo Silva Araujo Streit, Antônio Carlos Borges, Rafael Henrique Galinari, Yoshihisa Yoshimi, Paul Dupree, Gabriela Felix Persinoti, Mariana Abrahão Bueno Morais, Mario Tyago Murakami

Journal: Nature Communications

PubMed ID: 41491304

Doi: 10.1038/s41467-025-67225-2

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Targeted stress granule regulation by engineering a non-catalytic O-GlcNAc transferase

Authors: Na Wang, Fanjia Hou, Sihui Ma, Silan Liu, Haimei Wei, Weicheng Fang, Ke Zhang, Yun Ge

Journal: Nature Communications

PubMed ID: 41501012

Doi: 10.1038/s41467-025-66689-6

Products & Services: Protein Electrophoresis and Western

Intranasal replicon vaccine establishes mucosal immunity and protects against H5N1 and H7N9 influenza

Authors: Matthew R Ykema, Michael A Davis, Darshan N Kasal, Madeleine F Jennewein, Ethan Lo, Jasneet Singh, Samuel Beaver, Noah Cross, Eduard Melief, Sierra Reed, Christopher Press, Devin S Brandt, Wynton D McClary, Raodoh Mohamath, Pauline Fusco, Julie Bakken, Corey Casper, Airn Tolnay Hartwig, Alana Gerhardt, Richard A Bowen, Emily A Voigt

Journal: Nature Communications

PubMed ID: 41530119

Doi: 10.1038/s41467-025-64829-6

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Development of a split-toxin CRISPR screening platform to systematically identify regulators of human myoblast fusion

Authors: Haifeng Zhang, Renjie Shang, Zheng Zhang, Min Zhou, Anne Bigot, Yanqing Cai, Yanran Zhao, Yushu Wang, Aaryahi Deshmukh, Elena Kudryashova, Dmitri S Kudryashov, Cuiyu He, Vincent Mouly, Pengpeng Bi

Journal: Nature Communications

PubMed ID: 41540035

Doi: 10.1038/s41467-025-67583-x

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Human FcRL5 is an Fc receptor that simultaneously engages two IgGs

Authors: Shihua Chen, Shuhan Li, Zhiying Zhang, Junyu Xiao

Journal: SCIENCE ADVANCES

PubMed ID: 41477863

Doi: 10.1126/sciadv.aeb8865

Products & Services: Molecular Biology Reagents

Targeting transthyretin by one Cas9 variant with superfidelity and broad compatibility

Authors: Sixian Qi, Lifan Wei, Zhan Ding, Feiya Zhong, Sicong Yang, Leibin Wu, Xuan Yang, Bin Kang, Mo Dan, Jianhua Gan, Chunlei Li, Xiaoye Su

Journal: SCIENCE ADVANCES

PubMed ID: 41481737

Doi: 10.1126/sciadv.adu6505

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Argonaute-mediated RNA editing selectively repairs point mutations

Authors: Zhiwei Zhang, Jinyue Wang, Tongyu Guo, Xiaolan Yu, Fei Wang, Hang Zhang, Yang Liu, Wenqiang Li, Yibin Cheng, Yanhong Peng, Guangbo Yan, Jiakai Cui, Lixin Ma

Journal: Nucleic Acids Research

PubMed ID: 41495892

Doi: 10.1093/nar/gkaf1403

Products & Services: Molecular Biology Reagents

Structural evolution of the selectivity clamp confers ADPR-PP specificity in Namat, a phage nicotinamide ADP-ribose transferase

Authors: Meimei Lan, Li Xu, Yizhen Han, Tong Cui, Zhi Qiao, Yan-Bin Teng, Na Wang, Hongyu Bao

Journal: Nucleic Acids Research

PubMed ID: 41495901

Doi: 10.1093/nar/gkaf1492

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Structure and function of the nairovirus cap-snatching endonuclease

Authors: Wenhua Kuang, Zhenhua Tian, Gan Zhang, Fan Wu, Jinyue Li, Jingjing Tang, Huanyu Zhang, Xinyue Zhuo, Zhihong Hu, Manli Wang, Haiyan Zhao, Zengqin Deng

Journal: Nucleic Acids Research

PubMed ID: 41533578

Doi: 10.1093/nar/gkaf1515

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Strategic variations in sarbecovirus and merbecovirus Nsp1 linker regions for translation inhibition

Authors: Ruixi Yan, Mingbo Wu, Xiangyu Ge, Qianqian Jin, Moyu Wang, Haolong Zhou, Yan Li, Yue Wang, Shuai Yuan

Journal: Nucleic Acids Research

PubMed ID: 41538319

Doi: 10.1093/nar/gkag017

Products & Services: Protein and Antibody Isolation

From Natural Discovery to AI-Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Authors: Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu

Journal: Advanced Science

PubMed ID: 41486594

Doi: 10.1002/advs.202516600

Structure-Guided Engineering of a Cas12i Nuclease Unlocks Near-PAMless Genome Editing

Authors: Qitong Chen, Hanlin Gou, Chao Xu, Sihan Wang, Huitao Zhang, Minglei Song, Mengge Wang, Xingkun Ji, Xiaofei Wei, Yuanyan Tan, Hehua Quan, Pengyu Luo, Hanyu Shou, Pengpeng Liu, Yafeng Liang, Jian-Kang Zhu

Journal: Advanced Science

PubMed ID: 41532605

Doi: 10.1002/advs.202516670

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A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS-STING Activation for Cancer Immunotherapy

Authors: Shuang Liang, Yiwei Tian, Feiyu Zhao, Yue Han, Kongshuo Ma, Linna Hai, Kaiqing Yun, Yueyang Zhao, Siqi Zhang, Ziyi Zhang, Yuxuan Peng, Kuan Hu, Jing Zhong, Bai Xiang, Zhaohui Wang

Journal: Advanced Science

PubMed ID: 41560305

Doi: 10.1002/advs.202518356

Products & Services: Protein Electrophoresis and Western

A High Soluble-Fibre Allele in Wheat Encodes a Defective Cell Wall Peroxidase Responsible for Dimerization of Ferulate Moieties on Arabinoxylan

Authors: Rowan A C Mitchell, Ondrej Kosik, Abdul Kader Alabdullah, Anneke Prins, Maria Oszvald, Till K Pellny, Jackie Freeman, Kirstie Halsey, Caroline A Sparks, Alison Huttly, James Brett, Michelle Leverington-Waite, Simon Griffiths, Peter R Shewry, Alison Lovegrove

Journal: Plant Biotechnology Journal

PubMed ID: 41482806

Doi: 10.1111/pbi.70527

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Chemical inhibition of a bacterial immune system

Authors: Zhiyu Zang; Olivia K. Duncan; Dziugas Sabonis; Iana Fedorova; Yun Shi; Gause Miraj; Shuai Le; Jun Deng; Yuhao Zhu; Yanyao Cai; Chengqian Zhang; Garima Arya; Shelley A. H. Dixon; Steven P. Angus; Breck A. Duerkop; Haihua Liang; Robert H. Pepin; Thomas Ve; Joseph Bondy-Denomy; Giedre Tamulaitiene; Joseph P. Gerdt

Journal: Cell Host & Microbe

PubMed ID: 41619738

Doi: 10.1016/j.chom.2026.01.003

Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist

Authors: Juliet Gonzales; Tynan Young; Hyeran Choi; Miso Park; Yead Jewel; Chengcheng Fan; Rahul Purohit; Pamela J. Bjorkman; John C. Williams

Journal: Communications Biology

PubMed ID: 41053501

Doi: 10.1038/s42003-025-08819-w

A series of pyrimidine-based antifungals with anti-mold activity disrupt ER function in Aspergillus fumigatus

Authors: Martin T. Kelty; Aracely Miron-Ocampo; Sarah R. Beattie

Journal: Microbiology Spectrum

PubMed ID: 38916314

Doi: 10.1128/spectrum.01045-24

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Immunogenicity of JN.1 and KP.2 COVID-19 mRNA vaccines against emerging SARS-CoV-2 variants

Authors: Ninaad Lasrado, Annika Rössler, Isabella McConnell, Katherine Molloy, Ritobhas Bhowmik, Christine Happle, Ruoran Guan, Katherine McMahan, Juliana Pereira, Jinyan Liu, Erica Borducchi, Liping Wang, Krishna Shah, Bridget Wixted, Metodi V Stankov, Alexandra Dopfer-Jablonka, Ai-Ris Y Collier, Georg M N Behrens, Dan H Barouch

Journal: Vaccine

PubMed ID: 41265004

Doi: 10.1016/j.vaccine.2025.127997

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A colorimetric and surface-enhanced Raman scattering dual-readout lateral flow assay improves the accuracy of early diagnosis of Alzheimer's disease by simultaneously detecting Aβ42 oligomers and phosphorylated tau

Authors: Liding Zhang , Xuewei , Taoping Zhang, Qingshi Chen, Qian Zhang , Ying Su, Min Zhang, Haiming Luo

Journal: SENSORS AND ACTUATORS B-CHEMICAL

PubMed ID: 54633

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The ubiquitin ligase KLHL6 drives resistance to CD8+ T cell dysfunction

Authors: Hongcheng Cheng, Yapeng Su, Xiaoli Pan, Yue Xu, Ermei Xie, Jing Du, Daniel G Chen, Xiaomeng Dai, Raphael Gottardo, Philip D Greenberg, Guideng Li

Journal: Nature

PubMed ID: 41535474

Doi: 10.1038/s41586-025-09926-8

The visual system of the longest-living vertebrate, the Greenland shark

Authors: Lily G Fogg, Emily Tom, Maxime Policarpo, William Cho, Fangyuan Gao, Doreen Hii, Aaron E Fawcett, Nicolas Boileau, Amalie Bech-Poulsen, Kirstine F Steffensen, Cherlyn J Ng, Peter G Bushnell, John Fleng Steffensen, Richard Brill, Walter Salzburger, Dorota Skowronska-Krawczyk

Journal: Nature Communications

PubMed ID: 41491153

Doi: 10.1038/s41467-025-67429-6

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Restoration of ovarian endocrine function with encapsulated immune-isolated human ovarian xenograft in ovariectomized mice

Authors: Margaret A Brunette, Monica A Rionda, Delaney Sinko, Jordan H Machlin, Gabrielle M Blevins, Marisa Leo, Ansen Tan, Bipasha Ray, Marilia Cascalho, Vasantha Padmanabhan, Ariella Shikanov

Journal: SCIENCE ADVANCES

PubMed ID: 41477848

Doi: 10.1126/sciadv.adx6348

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Safeguarding genome integrity: Polo-like kinase Cdc5 and phosphatase Cdc14 orchestrate Topoisomerase II-mediated catenane resolution in mitosis

Authors: Lucia F Massari, Alice Finardi, Clara Visintin, Erika Calabrese, Ambra Dondi, Rosella Visintin

Journal: Nucleic Acids Research

PubMed ID: 41533572

Doi: 10.1093/nar/gkaf1509

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DNA binding and dimerization of the SOG1 NAC domain are functionally linked with its ability to undergo liquid–liquid phase separation

Authors: Kim Mignon, Rani Van der Eecken, Margot Galle, Manon Demulder, Joris Van Lindt, Lieven De Veylder, Henri De Greve, Remy Loris

Journal: Nucleic Acids Research

PubMed ID: 41556342

Doi: 10.1093/nar/gkaf1522

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AI-Based D-Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug-Resistant Bacterial Infection

Authors: Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li

Journal: Advanced Science

PubMed ID: 41532671

Doi: 10.1002/advs.202518522

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A Modular Vaccine Platform Against SARS-CoV-2 Based on Self-Assembled Protein Nanoparticles

Authors: Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji-Joon Song, Meehyein Kim, Sangyong Jon

Journal: Advanced Science

PubMed ID: 41532509

Doi: 10.1002/advs.202513431

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Functional and Mechanistic Investigation of a Distinct DUF6895 Family Epimerase Involved in Lasso Peptide Modification

Authors: Menghan Shi, Yuwei Duan, Shao-Yang Hou, Liangxu Xie, Weifeng Sun, Liubin Feng, Youming Zhang, Xiaoying Bian, and Guannan Zhong

Journal: ACS catalysis

Doi: 10.1021/acscatal.5c08590

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In Vivo Generation and Manipulation of CAR-T-mimicking Cells via Magnetic Bispecific Nano-antibody for Solid Tumor Therapy

Authors: Yueqiang Zhu, Chaoran Chen, Junbin Chen, Miao Su, Wanling Huang, Sichen Liu, Mingda Yang, Chengqiong Mao, Song Shen, Xianzhu Yang, Jun Wang

Journal: Advanced materials (Deerfield Beach, Fla.)

PubMed ID: 41495981

Doi: 10.1002/adma.202520493

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Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes

Authors: S Haydar, R Bednarz, P Laurette, I Sobitov, N Díaz I Pedrosa, P Videm, T Lueneburg, S Kuß, H Lahm, M Dreßen, M Krane, C Schmidt, B A Grüning, N Voigt, K Streckfuss-Bömeke, R Gilsbach

Journal: Nature Communications

PubMed ID: 41526351

Doi: 10.1038/s41467-025-67220-7

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Wnt3a promotes in situ dentin formation through NKD1- MSX1 axis-mediated odontogenic differentiation of dental pulp stem cells

Authors: Haoran Du, Qiong Li, Chenchen Zhou, Junji Xu, Kang Gao, Zixiao Li, Yifan Xu, Ousheng Liu, Bing Li, Jianguang Xu, Jingsong Wang, Hideaki Kagami, Xianqi Li, Su Chen, Jian Zhou

Journal: International journal of oral science

PubMed ID: 41526338

Doi: 10.1038/s41368-025-00406-3

Products & Services: Protein Electrophoresis and Western

A CLOCK-targeting lncRNA induces trained immunity against tuberculosis

Authors: Shanshan Yu, Qiyao Chai, Zhe Lu, Changgen Qiu, Yanzhao Zhong, Yiru Wang, Zehui Lei, Lihua Qiang, Yingxu Fang, Xinwen Zhang, Bingxi Li, Mengqiu Gao, Lingqiang Zhang, Gong Cheng, Jing Wang, Cui Hua Liu, Yu Pang

Journal: Cell Host & Microbe

PubMed ID: 41475336

Doi: 10.1016/j.chom.2025.12.002

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Screening for novel variable domains of the heavy chains of heavy-chain antibodies targeting different epitopes of thrombomodulin and Luminex fluorescence immunoassay for soluble thrombomodulin

Authors: Congcong Jia, Min Zhu, Yuelan He, Meixiang Yu, Xinyi Xia, Weiwei Ji, Xiang Cao, Jianzhong Lu, Hai Zhang

Journal: International Journal of Biological Macromolecules

PubMed ID: 41314569

Doi: 10.1016/j.ijbiomac.2025.149289

Products & Services: Gene Synthesis Peptide Synthesis

Characterization and therapy of fertilization failure in murine and human models with HNRNPR mutations

Authors: Shiming Gan, Yangyang Li, Lin Yin, Xiaotong Yang, Chen Lou, Sisi Li, Mingde Lin, Xin Li, Wenchao Xu, Jiaming Zhou, Peiran Hu, Zhendong Yao, Yuan Yuan, Jianzhong Sheng, Chen Zhang, Wei Yang, Youjiang Li, Hefeng Huang

Journal: EMBO Molecular Medicine

PubMed ID: 41618099

Doi: 10.1038/s44321-026-00374-z

Products & Services: Protein Electrophoresis and Western

Ependymoglial cells are critical for cortex regeneration in axolotls

Authors: Sulei Fu, Yan-Yun Zeng, Cheng Peng, Liqun Wang, Yuxian Feng, Kun Wang, Yanmei Liu, Ji-Feng Fei

Journal: Nature Communications

PubMed ID: 41559073

Doi: 10.1038/s41467-026-68538-6

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Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Journal: PLOS Pathogens

PubMed ID: 36399443

Doi: 10.1371/journal.ppat.1010951

Molecular mechanism of ziresovir targeting the fusion glycoprotein of respiratory syncytial virus

Authors: Mengrong Yan; Jingjing Zou; Zhao Gao; Haiqing Yuan; Jim Zhen Wu; Gang Zou; Fengjiang Liu; Wei Peng

Journal: PLOS Pathogens

PubMed ID: 41576151

Doi: 10.1371/journal.ppat.1013864

Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor

Authors: Gang Ye; Fan Bu; Hailey Turner-Hubbard; Morgan Herbst; Lanying Du; Ge Yang; Bin Liu; Fang Li

Journal: Nature

PubMed ID: 41813895

Doi: 10.1038/s41586-026-10240-0

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SARS-CoV-2 Mpro inhibitors from Siphonostegia chinensis : an integrated biophysical and computational study

Authors: Yingjie Ren; Wei Wang; Dai Zhang; Mingliang Zhang; Hui Zhang; Yali Wu; Feiyan Liu; Liuqing Yang; Pan Wang; Lei Chen; Xiaofei Chen; Jinfa Tang; Xianqing Ren

Journal: Frontiers in chemistry

PubMed ID: 42040628

Doi: 10.3389/fchem.2026.1790228

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Authors: Ting-Syuan Lin; Jingting Wan; Jingjin He; Shidong Cui; Yun Huang; Bojian Zhang; Hsi-Yuan Huang; Kexin Zhu; Jihang Chen; Tao Zhang; Shangfu Li; Liao Hu; Yongfei Wang; Hsien-Da Huang; Ping Tang; Yang-Chi-Dung Lin

Journal: Pharmaceutics

PubMed ID: 41900810

Doi: 10.3390/pharmaceutics18030324

Products & Services: Protein Electrophoresis and Western

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M pro and cathepsin L

Authors: Michael Dominic Sacco; Chunlong Ma; Panagiotis Lagarias; Ang Gao; Julia Alma Townsend; Xiangzhi Meng; Peter Dube; Xiujun Zhang; Yanmei Hu; Naoya Kitamura; Brett Hurst; Bart Tarbet; Michael Thomas Marty; Antonios Kolocouris; Yan Xiang; Yu Chen; Jun Wang

Journal: biorxiv

PubMed ID: 32766590

Doi: 10.1101/2020.07.27.223727

Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist

Authors: Juliet Gonzales; Tynan Young; Hyeran Choi; Miso Park; Yead Jewel; Chengcheng Fan; Rahul Purohit; Pamela J. Bjorkman; John C. Williams

Journal: Communications Biology

PubMed ID: 41053501

Doi: 10.1038/s42003-025-08819-w

Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist

Authors: Juliet Gonzales; Tynan Young; Hyeran Choi; Miso Park; Yead Jewel; Chengcheng Fan; Rahul Purohit; Pamela J. Bjorkman; John C. Williams

Journal: Communications Biology

PubMed ID: 41053501

Doi: 10.1038/s42003-025-08819-w

A series of pyrimidine-based antifungals with anti-mold activity disrupt ER function in Aspergillus fumigatus

Authors: Martin T. Kelty; Aracely Miron-Ocampo; Sarah R. Beattie

Journal: Microbiology Spectrum

PubMed ID: 38916314

Doi: 10.1128/spectrum.01045-24

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A series of pyrimidine-based antifungals with anti-mold activity disrupt ER function in Aspergillus fumigatus

Authors: Martin T. Kelty; Aracely Miron-Ocampo; Sarah R. Beattie

Journal: Microbiology Spectrum

PubMed ID: 38916314

Doi: 10.1128/spectrum.01045-24

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Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex

Authors: Christopher J. Lupton, Charles Bayly-Jones, Shuqi Dong, Terrance Lam, Wentong Luo, Gareth D. Jones, Chantel Mastos, Nicholas J. Frescher, San S. Lim, Alastair C. Keen, Luke E. Formosa, Hari Venugopal, Yong-Gang Chang, Michelle L. Halls, Andrew M. Ellisdon

Journal: Cell

PubMed ID: 41512879

Doi: 10.1016/j.cell.2025.12.005

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Polyamine-dependent metabolic shielding regulates alternative splicing

Authors: Amaia Zabala-Letona, Mikel Pujana-Vaquerizo, Belen Martinez-Laosa, Maria Ponce-Rodriguez, Saioa Garcia-Longarte, Isabel Mendizabal, Ana Gimeno, Malgorzata Rogalska, Joycelyn Tan, Diana Cabrera, Sebastiaan van Liempd, Pilar Ximenez-Embun, Sergio Espinosa, Maider Fagoaga-Eugui, Francesca Peccati, Maciej Zakrzewski, Ianire Astobiza, Mikel Arana-Castañares, Sarah Cherkaoui, Maria Sendino, Inés Martín-Barros, Amaia Ercilla, Laura Bozal-Basterra, Onintza Carlevaris, Amaia Arruabarrena-Aristorena, Encarnación Pérez-Andrés, Telmo Santamaría-Zamorano, Juan A Ferrer-Bonsoms, Fernando Carazo, Maciej Cieśla, Cesar Lobato, Joan Seoane, Natalia Martín-Martín, Rosa Barrio, James D Sutherland, Ana M Aransay, Juan Manuel Falcón-Pérez, Barbara Martínez-Pastor, Angel Rubio, Francisco J Blanco, Michael D Hogarty, Raphael J Morscher, Edurne Berra, Remigiusz A Serwa, Jesús Jiménez-Barbero, Gonzalo Jiménez-Osés, Alejo Efeyan, Lydia Finley, Jose M Lizcano, Javier Muñoz, Juan Valcarcel, Arkaitz Carracedo

Journal: Nature

PubMed ID: 41535471

Doi: 10.1038/s41586-025-09965-1

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A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands

Authors: Shihong Zhang, Tzu-Hao Tang, Sinéad Kinsella, Francesco Mazziotta, Michael T Schweizer, Megan S McAfee, Ariunaa Munkhbat, Yapeng Su, Valentin Voillet, Lauren E Martin, Colton W Smith, Yuta Asano, Menna Hailemariam, Jakob Bakhtiari, Bo Lee, Cecilia Yeung, Hung Chen, Alessandro M Rizzi, Daniel G Chen, Kelsey Furiya, Nick Horst, Tianzi Zhang, Phung Le, Kelly McKenna, Shannon K Oda, Anthony Rongvaux, Phillip D Greenberg, Thomas M Schmitt, Aude G Chapuis

Journal: Nature Communications

PubMed ID: 41484084

Doi: 10.1038/s41467-025-67446-5

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Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization

Authors: Aurélie Favarin, Rayan Said, Hong Wang, Emilie Zeine, Amaury Pierrard, Julien Pernier, Hemalatha Narassimprakash, Stéphane Roméro, Alexis M Gautreau, René-Marc Mège, Christophe Le Clainche

Journal: SCIENCE ADVANCES

PubMed ID: 41477870

Doi: 10.1126/sciadv.ady4863

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Dual-receptor targeting of type I dendritic cells with DNA-scaffolded nanoparticles enhances STING-licensed antitumor immunity

Authors: Deblin Jana, Emilia Herdes, Justin Moustouka, Kayla M Mash, Jingge Chen, Kareem Ebeid, Marwa Sallam, Akram Abbasi, Tejal Desai

Journal: SCIENCE ADVANCES

PubMed ID: 41481710

Doi: 10.1126/sciadv.aeb0452

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Allospecific splenic Tr1 cells drive effector T cell exhaustion through up-regulated Areg-EGFR signaling to promote transplant tolerance

Authors: Amar Singh, Adam Herman, Devanjan Dey, Samuel Menge, Shilpi Singh, Anna Tran, Anders Matson, Ahmed Mourad, Parthasarathy Rangarajan, Ravi Masuria, Naoya Sato, Sarah Vadnais, Joseph Sushil Rao, Gatikrushna Singh, Melanie L Graham, Sabarinathan Ramachandran, Bernhard J Hering

Journal: SCIENCE ADVANCES

PubMed ID: 41499508

Doi: 10.1126/sciadv.aea0567

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On-demand cancer immunotherapy via single-cell encapsulation of synthetic circuit–engineered cells

Authors: Yue Zhao, Rui Li, Yirui Han, Chaochen Shi, Kyubae Lee, Guangjun Nie, Yazhou Chen

Journal: SCIENCE ADVANCES

PubMed ID: 41533781

Doi: 10.1126/sciadv.aea3573

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Cell surface engineering with a pseudofibrotic ECM reprograms the antifibrotic activity of mesenchymal stromal cells

Authors: Xianghua Zhong, Xinchao Liu, Jiajia Luo, Xinyang Liu, Xueting Wei, Xi Peng, Lu Wang, Huaimin Wang, Kunyu Zhang, Liming Bian, Peng Shi

Journal: SCIENCE ADVANCES

PubMed ID: 41544160

Doi: 10.1126/sciadv.aea0998

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Enhanced SfaTnpB enables single-base-specific, one-pot nucleic acid detection for high-sensitivity diagnostics

Authors: Bingrong Xu, Sheng Li, Yong Li, Shuhong Zhao, Xinyun Li, Jianlin Han, Di Wu, Shuaicheng Li, Ling Chen, Shengsong Xie, Xiaosong Han, Changzhi Zhao

Journal: Nucleic Acids Research

PubMed ID: 41505099

Doi: 10.1093/nar/gkaf1433

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Bringing the ends together: cryo-EM structures of mycobacterial Ku in complex with DNA define its role in NHEJ synapsis

Authors: Joydeep Baral, Ching-Seng Ang, Paul James McMillan, Kalyan Shobhana, Ayushi Saini, Elizabeth Hinde, Amit Kumar Das, Isabelle Rouiller

Journal: Nucleic Acids Research

PubMed ID: 41521670

Doi: 10.1093/nar/gkaf1418

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G34R cancer mutation alters the conformational ensemble and dynamics of the histone H3.3 tails

Authors: Harrison A Fuchs, Yunhui Peng, Shine Ayyapan, Ruben Rosas, Houfang Zhang, Anna R Panchenko, Catherine A Musselman

Journal: Nucleic Acids Research

PubMed ID: 41533587

Doi: 10.1093/nar/gkaf1381

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Multilayered regulation by RNA thermometers enables precise control of Cas9 expression in E. coli

Authors: Elise K Kammerdiener, Sarah K Garcia, Margaret K Bales, Dawn M Klingeman, Adam M Guss, Richard J Giannone, Robert L Hettich, Carrie A Eckert, William G Alexander

Journal: Nucleic Acids Research

PubMed ID: 41533573

Doi: 10.1093/nar/gkaf1495

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Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR-Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Authors: Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo

Journal: Advanced Science

PubMed ID: 41560288

Doi: 10.1002/advs.202514140

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Schwann cell-derived extracellular vesicles inhibit osteoclastogenesis through the PTEN/AKT axis in peripheral nerve-bone crosstalk.

Authors: Huijian Yang, Biao Yu, Ruiyang Li, Yang Hong, Mingzhu Shen, Tianzhuo Shen, Xiuhui Wang, Han Liu, Guangchao Wang, Ke Xu, Yuhai Ma, Mengmeng Li, Jiacan Su

Journal: Journal of nanobiotechnology

PubMed ID: 41530784

Doi: 10.1186/s12951-026-04021-0

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SPARK-seq: A high-throughput platform for aptamer discovery and kinetic profiling

Authors: Guoyan Luo, Jia Song, Yongbo Fu, Yuanjie Jiang, Yuan Gao, Zhixing Zhong, Ling Li, Yong Wei, Hao-Ran Jia, Lu Guo, Ting Fu, Qin Wu, Weihong Tan

Journal: Science (New York, N.Y.)

PubMed ID: 41477891

Doi: 10.1126/science.adv6127

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Phage-associated Cas12p nucleases require binding to bacterial thioredoxin for activation and cleavage of target DNA

Authors: Zhipeng Wang, Yujue Wang, Hui Gao, Jiani Dai, Na Tang, Yannan Wang, Quanjiang Ji

Journal: Nature Microbiology

PubMed ID: 41492065

Doi: 10.1038/s41564-025-02224-z

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Antibody-induced internalization and degradation of PLA2R amplifies CD4+ T cell activation

Authors: Yuning Liu, Yinyin Li, Hui Zhou, Jieli Yu, Pei Deng, Weiwei Xu, Bingqian Pan, Lei Zhang, Hong Zhou, Jing Zhang, Xiaohan Liu, Min Shi, Xianchi Dong, Bei Tong, Enguang Bi, Nannan Guo, Yu Hu

Journal: Theranostics

PubMed ID: 41328348

Doi: 10.7150/thno.123035

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Reversible phase dynamics of PsAF5 regulate mitophagy to balance redox levels in Phytophthora sojae

Authors: Jinzhu Chen, Wenhao Li, Qin Peng, Hongwei Zhu, Tan Dai, Jianqiang Miao, Xili Liu

Journal: SCIENCE ADVANCES

PubMed ID: 41533793

Doi: 10.1126/sciadv.adz2785

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Structural decoding of reversible covalent linkage of odorants in human olfactory receptor OR6A2

Authors: Tian Wang, Yiran Wu, Ling Wang, Shanshan Li, Fei Zhao, Lijie Wu, Yue Liu, Jingzi Qin, Qiwen Tan, Junlin Liu, Liting Zeng, Yilin Chen, Shenyuan Gao, Wenqing Shui, Suwen Zhao, Tian Hua, Zhi-Jie Liu

Journal: Cell

PubMed ID: 41570822

Doi: 10.1016/j.cell.2025.12.017

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Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Journal: PLOS Pathogens

PubMed ID: 36399443

Doi: 10.1371/journal.ppat.1010951

Molecular mechanism of ziresovir targeting the fusion glycoprotein of respiratory syncytial virus

Authors: Mengrong Yan; Jingjing Zou; Zhao Gao; Haiqing Yuan; Jim Zhen Wu; Gang Zou; Fengjiang Liu; Wei Peng

Journal: PLOS Pathogens

PubMed ID: 41576151