An antibody screen is a laboratory test used to detect and identify antibodies in a person's blood. It is commonly performed during blood donation, pregnancy, or before a blood transfusion to determine the presence of unexpected antibodies that could potentially cause a transfusion reaction or other medical complications. During an antibody screen, a small sample of the person's blood is taken and tested against a panel of known red blood cell antigens. The antigens are substances located on the surface of red blood cells. If the person's blood contains antibodies that react with any of the antigens in the panel, it indicates the presence of unexpected antibodies. In the context of blood transfusions, an antibody screen is conducted to ensure compatibility between the donor's blood and the recipient's blood. If unexpected antibodies are detected in the recipient's blood, the blood bank will perform additional tests, such as crossmatching, to find a compatible blood unit for transfusion. During pregnancy, an antibody screen is a routine part of prenatal care. It helps identify antibodies in the mother's blood that could affect the health of the fetus, particularly if the mother has been previously exposed to foreign red blood cell antigens. Some examples of antibodies that can cause hemolytic disease of the newborn (HDN) include Rh antibodies and antibodies against other blood group antigens. The antibody screen is an essential tool for ensuring safe blood transfusions and providing appropriate care during pregnancy. It allows healthcare providers to detect and manage potential complications related to incompatible blood or maternal-fetal blood group incompatibilities. The results of the antibody screen guide medical decisions to ensure the best possible outcomes for patients and infants.
GenSmart Optimization is a free online tool for performing codon optimization to improve gene expression. GenScript's patented algorithms are integrated into the tool to optimize the computing capability of high-performance sequence generation.
GenSmart™ Design is a free online DNA construct design tool developed by GenScript. GenSmart™ Design has two design modules, the Create Construct module for individual plasmid design and the Create Library module for DNA library design.
This online tool shows commonly used genetic codon frequency table in expression host organisms including Escherichia coli and other common host organisms.
Antibody Production Services
Comprehensive custom antibody production services including monoclonal and polyclonal antibody production services with industry leading turnaround times.
Polyclonal Antibody Services
The fastest custom polyclonal antibody production services in the industry with unmatched guarantees.
Custom Monoclonal Antibody Development Services
Developing custom monoclonal antibodies with standard or fully custom protocols including everything from antigen synthesis to antibody scale-up options.
Phospho-Specific Antibody Services
Guaranteed ELISA titer of ≥ 1:64,000 and < 10% cross reactivity with non-phospho peptide.
Immunoassay Development Services
Our custom immunoassay development service offering comprehensive high-throughput assay development with fast turnaround and high efficiency.
Large-scale Antibody Manufacturing
Our large-scale antibody manufacturing services offer polyclonal and monoclonal antibody production of gram quantities for industrial antibody yields.
COVID-19 Reagent Antibodies
On demand SARS-CoV-2 control mAbs ideal for diagnostics, therapeutic, and vaccine development.
If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: [email protected]