Resources

List by Alphabet: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

nuclear pore

Nuclear pores are large multi-subunit transport channels that perforate the nuclear membranes. A nuclear pore is part of a large complex of proteins, known as a nuclear pore complex that spans the nuclear envelope, which is the double membrane surrounding the eukaryotic cell nucleus.

The nuclear pore is a protein-lined channel in the nuclear envelope that regulates the transportation of molecules between the nucleus and the cytoplasm.

Nuclear pores (NPs) form another anchoring site for the genome at the nuclear envelope. Nuclear pores are large multi-subunit transport channels that perforate the nuclear membranes. They occupy positions in the nuclear envelope that are depleted of lamins. Electron microscopy indicates that the NL is generally in close contact with relatively condensed chromatin (consistent with the repressed state of LADs). In contrast, nuclear pores are surrounded by less condensed chromatin. Indeed, ChIP and DamID mapping studies in yeast and fly have revealed that nuclear pore proteins interact preferentially with a subset of active genes.

Related tool: qpcr primer design

Related Biology Tools

  • GenSmart™ Codon Optimization

    GenSmart Optimization is a free online tool for performing codon optimization to improve gene expression. GenScript's patented algorithms are integrated into the tool to optimize the computing capability of high-performance sequence generation.

    Learn More

  • DNA Construct Design Tool

    GenSmart™ Design is a free online DNA construct design tool developed by GenScript. GenSmart™ Design has two design modules, the Create Construct module for individual plasmid design and the Create Library module for DNA library design.

    Learn More

  • Codon Frequency Tables

    This online tool shows commonly used genetic codon frequency table in expression host organisms including Escherichia coli and other common host organisms.

    Learn More

Service and Products

Gene Synthesis

Offer gene synthesis of 100% sequence guarantee, free codon optimization, DNA synthesis in as fast as 4 days.

ORF cDNA Clones and Custom Clones

Largest commercial ORF clones database, 70,000 next-day shipping ORF clones.

Plasmid DNA Preparation

High quality plasmids supported by fully-automated platform, 100% full insert sequence accuracy guaranteed.

Express Cloning & Subcloning

$49 and 2 day turnaround, choose from over 150 IP FREE vectors.

Mutation and Library Services

Mutagenesis Portfolio offers several mutation and library services to meet various customers’ needs.

Oligo Synthesis

Bridge the gap between chemically synthesized oligos and bological applications.

If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: [email protected]

If your term is adopted, we will send 1,000 EzCoupon points to your GenScript account.