Gene Symbol | fzd8a |
Entrez Gene ID | 58073 |
Full Name | frizzled class receptor 8a |
Synonyms | fz5,fz8a,fzc,wu:fd02c05,zg05 |
General protein information |
|
Gene Type | protein-coding |
Organism | Danio rerio(zebrafish) |
ORF » Species Summary » Danio rerio » fzd8a cDNA ORF clone
Gene Symbol | fzd8a |
Entrez Gene ID | 58073 |
Full Name | frizzled class receptor 8a |
Synonyms | fz5,fz8a,fzc,wu:fd02c05,zg05 |
General protein information |
|
Gene Type | protein-coding |
Organism | Danio rerio(zebrafish) |
mRNA | Protein | Name |
---|---|---|
NM_130918.2 | NP_570993.2 | frizzled-8 |
Homo sapiens (human) | FZD8 | NP_114072.1 |
Mus musculus (house mouse) | Fzd8 | NP_032084.2 |
Rattus norvegicus (Norway rat) | Fzd8 | NP_001037716.1 |
Rattus norvegicus (Norway rat) | LOC100909849 | XP_003751769.1 |
Xenopus tropicalis (tropical clawed frog) | fzd8 | NP_001090860.2 |
Canis lupus familiaris (dog) | FZD8 | XP_005617125.1 |
Caenorhabditis elegans (roundworm) | cfz-2 | NP_503965.2 |
Pan troglodytes (chimpanzee) | FZD8 | XP_001142144.2 |
Danio rerio (zebrafish) | fzd8a | NP_570993.2 |
FZD8 | XP_001096837.1 | |
Bos taurus (cattle) | FZD8 | XP_005214377.1 |
Wnt/?-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity.
So J, Khaliq M, Evason K, Ninov N, Martin BL, Stainier DYR, Shin D
Hepatology (Baltimore, Md.)(2017 Dec)
Dissecting the role of Wnt signaling and its interactions with FGF signaling during midbrain neurogenesis.
Dyer C, Blanc E, Stanley RJ, Knight RD
Neurogenesis (Austin, Tex.)2(1)e1057313(2015)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
fzd8a is expressed in the pharyngeal endoderm.
Title: Expression of five frizzleds during zebrafish craniofacial development.
These results demonstrated that overexpression of DNfz8a in Zoep embryos between 7 and 16hpf increased putative forebrain region demarcated by anf and distal-less2 expressions.
Title: Normal forebrain development may require continual Wnt antagonism until mid-somitogenesis in zebrafish.
Fz8a plays a critical role in the specification and maturation of oligodendrocyte progenitor cells (OPCs) in the ventral spinal cord.
Title: Frizzled 8a function is required for oligodendrocyte development in the zebrafish spinal cord.
wnt11 and Fz5 signaling promotes early eye development through the coordinated antagonism of signals that suppress retinal identity
Title: Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway.
Specification of an anterior neuroectoderm patterning by Frizzled8a-mediated Wnt8b signalling during late gastrulation in zebrafish.
Title: Specification of an anterior neuroectoderm patterning by Frizzled8a-mediated Wnt8b signalling during late gastrulation in zebrafish.
The following fzd8a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the fzd8a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ODa02500 | |
Clone ID Related Accession (Same CDS sequence) | NM_130918.2 | |
Accession Version | NM_130918.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1740bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-07 | |
Organism | Danio rerio(zebrafish) | |
Product | frizzled-8 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC056273.1. On or before Nov 28, 2007 this sequence version replaced NM_131137.1, NM_131554.1, NM_130918.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC056273.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGGAGTGCT ACCTGTTGGG GATTTACCTG TTCCTCGCGC TGGCTCTGCT GCCCCGATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_570993.2 |
CDS | 315..2054 |
Translation |
Target ORF information:
Target ORF information:
|
NM_130918.2 |
1 | ATGGAGTGCT ACCTGTTGGG GATTTACCTG TTCCTCGCGC TGGCTCTGCT GCCCCGATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Wnt/?-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity. |
Dissecting the role of Wnt signaling and its interactions with FGF signaling during midbrain neurogenesis. |