ADAM10 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADAM10
Entrez Gene ID	102
Full Name	ADAM metallopeptidase domain 10
Synonyms	AD10,AD18,CD156c,CDw156,HsT18717,MADM,RAK,kuz
General protein information	Preferred Names ADAM metallopeptidase domain 10 Names disintegrin and metalloproteinase domain-containing protein 10 a disintegrin and metalloprotease domain 10 kuzbanian protein homolog mammalian disintegrin-metalloprotease
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q21.3
Summary	Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016].
Disorder MIM:	602192
Disorder Html:	Reticulate acropigmentation of Kitamura, 615537 (3); {Alzheimer disease 18, susceptibility to}, 615590 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001110.3	NP_001101.1	disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein
XM_024449818.1	XP_024305586.1	disintegrin and metalloproteinase domain-containing protein 10 isoform X1
NM_001320570.1	NP_001307499.1	disintegrin and metalloproteinase domain-containing protein 10 isoform 2 precursor
NM_001110.4	NP_001101.1	disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein
XM_017021861.1	XP_016877350.1	disintegrin and metalloproteinase domain-containing protein 10 isoform X1
NM_001320570.2	NP_001307499.1	disintegrin and metalloproteinase domain-containing protein 10 isoform 2 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ADAM10	NP_776921.1
Danio rerio (zebrafish)	adam10a	NP_001152786.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003070	XP_312756.5
Xenopus tropicalis (tropical clawed frog)	adam10	NP_001037869.1
Pan troglodytes (chimpanzee)	ADAM10	XP_001172405.1
Mus musculus (house mouse)	Adam10	NP_031425.2
Rattus norvegicus (Norway rat)	Adam10	NP_062127.1
	ADAM10	XP_001097016.1
Homo sapiens (human)	ADAM10	NP_001101.1
Canis lupus familiaris (dog)	ADAM10	XP_005638749.1
Gallus gallus (chicken)	ADAM10	NP_989592.2

Gene Ontology

The following ADAM10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAM10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21096	NM_001110.4 Latest version!	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu85226	XM_017021861.1 Latest version!	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$391.30 $559.00
OHu85226	XM_024449818.1 Latest version!	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$391.30 $559.00
OHu48053	NM_001320570.2 Latest version!	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu21096	NM_001110.3	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu48053	NM_001320570.1	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADAM10 ( NM_001110.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001101.1 Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 1, mRNA.

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CloneID	OHu21096
Clone ID Related Accession (Same CDS sequence)	NM_001110.3 , NM_001110.4
Accession Version	NM_001110.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2247bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF009615.1, DA941750.1, BX372217.2, AY726599.1, BE327886.1 and AA243020.1. This sequence is a reference standard in the RefSeqGene project. On Dec 24, 2013 this sequence version replaced NM_001110.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.96248.1, SRR1803613.229001.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTTGC TGAGAGTGTT AATTCTGCTC CTCTCCTGGG CGGCGGGGAT GGGAGGTCAG 
TATGGGAATC CTTTAAATAA ATATATCAGA CATTATGAAG GATTATCTTA CAATGTGGAT 
TCATTACACC AAAAACACCA GCGTGCCAAA AGAGCAGTCT CACATGAAGA CCAATTTTTA 
CGTCTAGATT TCCATGCCCA TGGAAGACAT TTCAACCTAC GAATGAAGAG GGACACTTCC 
CTTTTCAGTG ATGAATTTAA AGTAGAAACA TCAAATAAAG TACTTGATTA TGATACCTCT 
CATATTTACA CTGGACATAT TTATGGTGAA GAAGGAAGTT TTAGCCATGG GTCTGTTATT 
GATGGAAGAT TTGAAGGATT CATCCAGACT CGTGGTGGCA CATTTTATGT TGAGCCAGCA 
GAGAGATATA TTAAAGACCG AACTCTGCCA TTTCACTCTG TCATTTATCA TGAAGATGAT 
ATTAACTATC CCCATAAATA CGGTCCTCAG GGGGGCTGTG CAGATCATTC AGTATTTGAA 
AGAATGAGGA AATACCAGAT GACTGGTGTA GAGGAAGTAA CACAGATACC TCAAGAAGAA 
CATGCTGCTA ATGGTCCAGA ACTTCTGAGG AAAAAACGTA CAACTTCAGC TGAAAAAAAT 
ACTTGTCAGC TTTATATTCA GACTGATCAT TTGTTCTTTA AATATTACGG AACACGAGAA 
GCTGTGATTG CCCAGATATC CAGTCATGTT AAAGCGATTG ATACAATTTA CCAGACCACA 
GACTTCTCCG GAATCCGTAA CATCAGTTTC ATGGTGAAAC GCATAAGAAT CAATACAACT 
GCTGATGAGA AGGACCCTAC AAATCCTTTC CGTTTCCCAA ATATTGGTGT GGAGAAGTTT 
CTGGAATTGA ATTCTGAGCA GAATCATGAT GACTACTGTT TGGCCTATGT CTTCACAGAC 
CGAGATTTTG ATGATGGCGT ACTTGGTCTG GCTTGGGTTG GAGCACCTTC AGGAAGCTCT 
GGAGGAATAT GTGAAAAAAG TAAACTCTAT TCAGATGGTA AGAAGAAGTC CTTAAACACT 
GGAATTATTA CTGTTCAGAA CTATGGGTCT CATGTACCTC CCAAAGTCTC TCACATTACT 
TTTGCTCACG AAGTTGGACA TAACTTTGGA TCCCCACATG ATTCTGGAAC AGAGTGCACA 
CCAGGAGAAT CTAAGAATTT GGGTCAAAAA GAAAATGGCA ATTACATCAT GTATGCAAGA 
GCAACATCTG GGGACAAACT TAACAACAAT AAATTCTCAC TCTGTAGTAT TAGAAATATA 
AGCCAAGTTC TTGAGAAGAA GAGAAACAAC TGTTTTGTTG AATCTGGCCA ACCTATTTGT 
GGAAATGGAA TGGTAGAACA AGGTGAAGAA TGTGATTGTG GCTATAGTGA CCAGTGTAAA 
GATGAATGCT GCTTCGATGC AAATCAACCA GAGGGAAGAA AATGCAAACT GAAACCTGGG 
AAACAGTGCA GTCCAAGTCA AGGTCCTTGT TGTACAGCAC AGTGTGCATT CAAGTCAAAG 
TCTGAGAAGT GTCGGGATGA TTCAGACTGT GCAAGGGAAG GAATATGTAA TGGCTTCACA 
GCTCTCTGCC CAGCATCTGA CCCTAAACCA AACTTCACAG ACTGTAATAG GCATACACAA 
GTGTGCATTA ATGGGCAATG TGCAGGTTCT ATCTGTGAGA AATATGGCTT AGAGGAGTGT 
ACGTGTGCCA GTTCTGATGG CAAAGATGAT AAAGAATTAT GCCATGTATG CTGTATGAAG 
AAAATGGACC CATCAACTTG TGCCAGTACA GGGTCTGTGC AGTGGAGTAG GCACTTCAGT 
GGTCGAACCA TCACCCTGCA ACCTGGATCC CCTTGCAACG ATTTTAGAGG TTACTGTGAT 
GTTTTCATGC GGTGCAGATT AGTAGATGCT GATGGTCCTC TAGCTAGGCT TAAAAAAGCA 
ATTTTTAGTC CAGAGCTCTA TGAAAACATT GCTGAATGGA TTGTGGCTCA TTGGTGGGCA 
GTATTACTTA TGGGAATTGC TCTGATCATG CTAATGGCTG GATTTATTAA GATATGCAGT 
GTTCATACTC CAAGTAGTAA TCCAAAGTTG CCTCCTCCTA AACCACTTCC AGGCACTTTA 
AAGAGGAGGA GACCTCCACA GCCCATTCAG CAACCCCAGC GTCAGCGGCC CCGAGAGAGT 
TATCAAATGG GACACATGAG ACGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101.1
CDS	445..2691
Translation	MVLLRVLILLLSWAAGMGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQPIQQPQRQRPRESYQMGHMRR

Target ORF information:

RefSeq Version	NM_001110.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001110.3

ORF Insert Sequence:

ATGGTGTTGC TGAGAGTGTT AATTCTGCTC CTCTCCTGGG CGGCGGGGAT GGGAGGTCAG 
TATGGGAATC CTTTAAATAA ATATATCAGA CATTATGAAG GATTATCTTA CAATGTGGAT 
TCATTACACC AAAAACACCA GCGTGCCAAA AGAGCAGTCT CACATGAAGA CCAATTTTTA 
CGTCTAGATT TCCATGCCCA TGGAAGACAT TTCAACCTAC GAATGAAGAG GGACACTTCC 
CTTTTCAGTG ATGAATTTAA AGTAGAAACA TCAAATAAAG TACTTGATTA TGATACCTCT 
CATATTTACA CTGGACATAT TTATGGTGAA GAAGGAAGTT TTAGCCATGG GTCTGTTATT 
GATGGAAGAT TTGAAGGATT CATCCAGACT CGTGGTGGCA CATTTTATGT TGAGCCAGCA 
GAGAGATATA TTAAAGACCG AACTCTGCCA TTTCACTCTG TCATTTATCA TGAAGATGAT 
ATTAACTATC CCCATAAATA CGGTCCTCAG GGGGGCTGTG CAGATCATTC AGTATTTGAA 
AGAATGAGGA AATACCAGAT GACTGGTGTA GAGGAAGTAA CACAGATACC TCAAGAAGAA 
CATGCTGCTA ATGGTCCAGA ACTTCTGAGG AAAAAACGTA CAACTTCAGC TGAAAAAAAT 
ACTTGTCAGC TTTATATTCA GACTGATCAT TTGTTCTTTA AATATTACGG AACACGAGAA 
GCTGTGATTG CCCAGATATC CAGTCATGTT AAAGCGATTG ATACAATTTA CCAGACCACA 
GACTTCTCCG GAATCCGTAA CATCAGTTTC ATGGTGAAAC GCATAAGAAT CAATACAACT 
GCTGATGAGA AGGACCCTAC AAATCCTTTC CGTTTCCCAA ATATTGGTGT GGAGAAGTTT 
CTGGAATTGA ATTCTGAGCA GAATCATGAT GACTACTGTT TGGCCTATGT CTTCACAGAC 
CGAGATTTTG ATGATGGCGT ACTTGGTCTG GCTTGGGTTG GAGCACCTTC AGGAAGCTCT 
GGAGGAATAT GTGAAAAAAG TAAACTCTAT TCAGATGGTA AGAAGAAGTC CTTAAACACT 
GGAATTATTA CTGTTCAGAA CTATGGGTCT CATGTACCTC CCAAAGTCTC TCACATTACT 
TTTGCTCACG AAGTTGGACA TAACTTTGGA TCCCCACATG ATTCTGGAAC AGAGTGCACA 
CCAGGAGAAT CTAAGAATTT GGGTCAAAAA GAAAATGGCA ATTACATCAT GTATGCAAGA 
GCAACATCTG GGGACAAACT TAACAACAAT AAATTCTCAC TCTGTAGTAT TAGAAATATA 
AGCCAAGTTC TTGAGAAGAA GAGAAACAAC TGTTTTGTTG AATCTGGCCA ACCTATTTGT 
GGAAATGGAA TGGTAGAACA AGGTGAAGAA TGTGATTGTG GCTATAGTGA CCAGTGTAAA 
GATGAATGCT GCTTCGATGC AAATCAACCA GAGGGAAGAA AATGCAAACT GAAACCTGGG 
AAACAGTGCA GTCCAAGTCA AGGTCCTTGT TGTACAGCAC AGTGTGCATT CAAGTCAAAG 
TCTGAGAAGT GTCGGGATGA TTCAGACTGT GCAAGGGAAG GAATATGTAA TGGCTTCACA 
GCTCTCTGCC CAGCATCTGA CCCTAAACCA AACTTCACAG ACTGTAATAG GCATACACAA 
GTGTGCATTA ATGGGCAATG TGCAGGTTCT ATCTGTGAGA AATATGGCTT AGAGGAGTGT 
ACGTGTGCCA GTTCTGATGG CAAAGATGAT AAAGAATTAT GCCATGTATG CTGTATGAAG 
AAAATGGACC CATCAACTTG TGCCAGTACA GGGTCTGTGC AGTGGAGTAG GCACTTCAGT 
GGTCGAACCA TCACCCTGCA ACCTGGATCC CCTTGCAACG ATTTTAGAGG TTACTGTGAT 
GTTTTCATGC GGTGCAGATT AGTAGATGCT GATGGTCCTC TAGCTAGGCT TAAAAAAGCA 
ATTTTTAGTC CAGAGCTCTA TGAAAACATT GCTGAATGGA TTGTGGCTCA TTGGTGGGCA 
GTATTACTTA TGGGAATTGC TCTGATCATG CTAATGGCTG GATTTATTAA GATATGCAGT 
GTTCATACTC CAAGTAGTAA TCCAAAGTTG CCTCCTCCTA AACCACTTCC AGGCACTTTA 
AAGAGGAGGA GACCTCCACA GCCCATTCAG CAACCCCAGC GTCAGCGGCC CCGAGAGAGT 
TATCAAATGG GACACATGAG ACGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM10 ( NM_001110.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001101.1 Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 1, mRNA.

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CloneID	OHu21096
Clone ID Related Accession (Same CDS sequence)	NM_001110.3 , NM_001110.4
Accession Version	NM_001110.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2247bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA941750.1, AF009615.1, BX372217.2, AY726599.1, BE327886.1, AA243020.1 and AC018904.6. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001110.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.236840.1, SRR1803613.120501.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000260408.8/ ENSP00000260408.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTGTTGC TGAGAGTGTT AATTCTGCTC CTCTCCTGGG CGGCGGGGAT GGGAGGTCAG 
TATGGGAATC CTTTAAATAA ATATATCAGA CATTATGAAG GATTATCTTA CAATGTGGAT 
TCATTACACC AAAAACACCA GCGTGCCAAA AGAGCAGTCT CACATGAAGA CCAATTTTTA 
CGTCTAGATT TCCATGCCCA TGGAAGACAT TTCAACCTAC GAATGAAGAG GGACACTTCC 
CTTTTCAGTG ATGAATTTAA AGTAGAAACA TCAAATAAAG TACTTGATTA TGATACCTCT 
CATATTTACA CTGGACATAT TTATGGTGAA GAAGGAAGTT TTAGCCATGG GTCTGTTATT 
GATGGAAGAT TTGAAGGATT CATCCAGACT CGTGGTGGCA CATTTTATGT TGAGCCAGCA 
GAGAGATATA TTAAAGACCG AACTCTGCCA TTTCACTCTG TCATTTATCA TGAAGATGAT 
ATTAACTATC CCCATAAATA CGGTCCTCAG GGGGGCTGTG CAGATCATTC AGTATTTGAA 
AGAATGAGGA AATACCAGAT GACTGGTGTA GAGGAAGTAA CACAGATACC TCAAGAAGAA 
CATGCTGCTA ATGGTCCAGA ACTTCTGAGG AAAAAACGTA CAACTTCAGC TGAAAAAAAT 
ACTTGTCAGC TTTATATTCA GACTGATCAT TTGTTCTTTA AATATTACGG AACACGAGAA 
GCTGTGATTG CCCAGATATC CAGTCATGTT AAAGCGATTG ATACAATTTA CCAGACCACA 
GACTTCTCCG GAATCCGTAA CATCAGTTTC ATGGTGAAAC GCATAAGAAT CAATACAACT 
GCTGATGAGA AGGACCCTAC AAATCCTTTC CGTTTCCCAA ATATTGGTGT GGAGAAGTTT 
CTGGAATTGA ATTCTGAGCA GAATCATGAT GACTACTGTT TGGCCTATGT CTTCACAGAC 
CGAGATTTTG ATGATGGCGT ACTTGGTCTG GCTTGGGTTG GAGCACCTTC AGGAAGCTCT 
GGAGGAATAT GTGAAAAAAG TAAACTCTAT TCAGATGGTA AGAAGAAGTC CTTAAACACT 
GGAATTATTA CTGTTCAGAA CTATGGGTCT CATGTACCTC CCAAAGTCTC TCACATTACT 
TTTGCTCACG AAGTTGGACA TAACTTTGGA TCCCCACATG ATTCTGGAAC AGAGTGCACA 
CCAGGAGAAT CTAAGAATTT GGGTCAAAAA GAAAATGGCA ATTACATCAT GTATGCAAGA 
GCAACATCTG GGGACAAACT TAACAACAAT AAATTCTCAC TCTGTAGTAT TAGAAATATA 
AGCCAAGTTC TTGAGAAGAA GAGAAACAAC TGTTTTGTTG AATCTGGCCA ACCTATTTGT 
GGAAATGGAA TGGTAGAACA AGGTGAAGAA TGTGATTGTG GCTATAGTGA CCAGTGTAAA 
GATGAATGCT GCTTCGATGC AAATCAACCA GAGGGAAGAA AATGCAAACT GAAACCTGGG 
AAACAGTGCA GTCCAAGTCA AGGTCCTTGT TGTACAGCAC AGTGTGCATT CAAGTCAAAG 
TCTGAGAAGT GTCGGGATGA TTCAGACTGT GCAAGGGAAG GAATATGTAA TGGCTTCACA 
GCTCTCTGCC CAGCATCTGA CCCTAAACCA AACTTCACAG ACTGTAATAG GCATACACAA 
GTGTGCATTA ATGGGCAATG TGCAGGTTCT ATCTGTGAGA AATATGGCTT AGAGGAGTGT 
ACGTGTGCCA GTTCTGATGG CAAAGATGAT AAAGAATTAT GCCATGTATG CTGTATGAAG 
AAAATGGACC CATCAACTTG TGCCAGTACA GGGTCTGTGC AGTGGAGTAG GCACTTCAGT 
GGTCGAACCA TCACCCTGCA ACCTGGATCC CCTTGCAACG ATTTTAGAGG TTACTGTGAT 
GTTTTCATGC GGTGCAGATT AGTAGATGCT GATGGTCCTC TAGCTAGGCT TAAAAAAGCA 
ATTTTTAGTC CAGAGCTCTA TGAAAACATT GCTGAATGGA TTGTGGCTCA TTGGTGGGCA 
GTATTACTTA TGGGAATTGC TCTGATCATG CTAATGGCTG GATTTATTAA GATATGCAGT 
GTTCATACTC CAAGTAGTAA TCCAAAGTTG CCTCCTCCTA AACCACTTCC AGGCACTTTA 
AAGAGGAGGA GACCTCCACA GCCCATTCAG CAACCCCAGC GTCAGCGGCC CCGAGAGAGT 
TATCAAATGG GACACATGAG ACGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101.1
CDS	174..2420
Translation	MVLLRVLILLLSWAAGMGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQPIQQPQRQRPRESYQMGHMRR

Target ORF information:

RefSeq Version	NM_001110.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001110.4

ORF Insert Sequence:

ATGGTGTTGC TGAGAGTGTT AATTCTGCTC CTCTCCTGGG CGGCGGGGAT GGGAGGTCAG 
TATGGGAATC CTTTAAATAA ATATATCAGA CATTATGAAG GATTATCTTA CAATGTGGAT 
TCATTACACC AAAAACACCA GCGTGCCAAA AGAGCAGTCT CACATGAAGA CCAATTTTTA 
CGTCTAGATT TCCATGCCCA TGGAAGACAT TTCAACCTAC GAATGAAGAG GGACACTTCC 
CTTTTCAGTG ATGAATTTAA AGTAGAAACA TCAAATAAAG TACTTGATTA TGATACCTCT 
CATATTTACA CTGGACATAT TTATGGTGAA GAAGGAAGTT TTAGCCATGG GTCTGTTATT 
GATGGAAGAT TTGAAGGATT CATCCAGACT CGTGGTGGCA CATTTTATGT TGAGCCAGCA 
GAGAGATATA TTAAAGACCG AACTCTGCCA TTTCACTCTG TCATTTATCA TGAAGATGAT 
ATTAACTATC CCCATAAATA CGGTCCTCAG GGGGGCTGTG CAGATCATTC AGTATTTGAA 
AGAATGAGGA AATACCAGAT GACTGGTGTA GAGGAAGTAA CACAGATACC TCAAGAAGAA 
CATGCTGCTA ATGGTCCAGA ACTTCTGAGG AAAAAACGTA CAACTTCAGC TGAAAAAAAT 
ACTTGTCAGC TTTATATTCA GACTGATCAT TTGTTCTTTA AATATTACGG AACACGAGAA 
GCTGTGATTG CCCAGATATC CAGTCATGTT AAAGCGATTG ATACAATTTA CCAGACCACA 
GACTTCTCCG GAATCCGTAA CATCAGTTTC ATGGTGAAAC GCATAAGAAT CAATACAACT 
GCTGATGAGA AGGACCCTAC AAATCCTTTC CGTTTCCCAA ATATTGGTGT GGAGAAGTTT 
CTGGAATTGA ATTCTGAGCA GAATCATGAT GACTACTGTT TGGCCTATGT CTTCACAGAC 
CGAGATTTTG ATGATGGCGT ACTTGGTCTG GCTTGGGTTG GAGCACCTTC AGGAAGCTCT 
GGAGGAATAT GTGAAAAAAG TAAACTCTAT TCAGATGGTA AGAAGAAGTC CTTAAACACT 
GGAATTATTA CTGTTCAGAA CTATGGGTCT CATGTACCTC CCAAAGTCTC TCACATTACT 
TTTGCTCACG AAGTTGGACA TAACTTTGGA TCCCCACATG ATTCTGGAAC AGAGTGCACA 
CCAGGAGAAT CTAAGAATTT GGGTCAAAAA GAAAATGGCA ATTACATCAT GTATGCAAGA 
GCAACATCTG GGGACAAACT TAACAACAAT AAATTCTCAC TCTGTAGTAT TAGAAATATA 
AGCCAAGTTC TTGAGAAGAA GAGAAACAAC TGTTTTGTTG AATCTGGCCA ACCTATTTGT 
GGAAATGGAA TGGTAGAACA AGGTGAAGAA TGTGATTGTG GCTATAGTGA CCAGTGTAAA 
GATGAATGCT GCTTCGATGC AAATCAACCA GAGGGAAGAA AATGCAAACT GAAACCTGGG 
AAACAGTGCA GTCCAAGTCA AGGTCCTTGT TGTACAGCAC AGTGTGCATT CAAGTCAAAG 
TCTGAGAAGT GTCGGGATGA TTCAGACTGT GCAAGGGAAG GAATATGTAA TGGCTTCACA 
GCTCTCTGCC CAGCATCTGA CCCTAAACCA AACTTCACAG ACTGTAATAG GCATACACAA 
GTGTGCATTA ATGGGCAATG TGCAGGTTCT ATCTGTGAGA AATATGGCTT AGAGGAGTGT 
ACGTGTGCCA GTTCTGATGG CAAAGATGAT AAAGAATTAT GCCATGTATG CTGTATGAAG 
AAAATGGACC CATCAACTTG TGCCAGTACA GGGTCTGTGC AGTGGAGTAG GCACTTCAGT 
GGTCGAACCA TCACCCTGCA ACCTGGATCC CCTTGCAACG ATTTTAGAGG TTACTGTGAT 
GTTTTCATGC GGTGCAGATT AGTAGATGCT GATGGTCCTC TAGCTAGGCT TAAAAAAGCA 
ATTTTTAGTC CAGAGCTCTA TGAAAACATT GCTGAATGGA TTGTGGCTCA TTGGTGGGCA 
GTATTACTTA TGGGAATTGC TCTGATCATG CTAATGGCTG GATTTATTAA GATATGCAGT 
GTTCATACTC CAAGTAGTAA TCCAAAGTTG CCTCCTCCTA AACCACTTCC AGGCACTTTA 
AAGAGGAGGA GACCTCCACA GCCCATTCAG CAACCCCAGC GTCAGCGGCC CCGAGAGAGT 
TATCAAATGG GACACATGAG ACGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM10 ( XM_024449818.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024305586.1 Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu85226
Clone ID Related Accession (Same CDS sequence)	XM_024449818.1 , XM_017021861.1
Accession Version	XM_024449818.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2025bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAGGG ACACTTCCCT TTTCAGTGAT GAATTTAAAG TAGAAACATC AAATAAAGTA 
CTTGATTATG ATACCTCTCA TATTTACACT GGACATATTT ATGGTGAAGA AGGAAGTTTT 
AGCCATGGGT CTGTTATTGA TGGAAGATTT GAAGGATTCA TCCAGACTCG TGGTGGCACA 
TTTTATGTTG AGCCAGCAGA GAGATATATT AAAGACCGAA CTCTGCCATT TCACTCTGTC 
ATTTATCATG AAGATGATAT TAACTATCCC CATAAATACG GTCCTCAGGG GGGCTGTGCA 
GATCATTCAG TATTTGAAAG AATGAGGAAA TACCAGATGA CTGGTGTAGA GGAAGTAACA 
CAGATACCTC AAGAAGAACA TGCTGCTAAT GGTCCAGAAC TTCTGAGGAA AAAACGTACA 
ACTTCAGCTG AAAAAAATAC TTGTCAGCTT TATATTCAGA CTGATCATTT GTTCTTTAAA 
TATTACGGAA CACGAGAAGC TGTGATTGCC CAGATATCCA GTCATGTTAA AGCGATTGAT 
ACAATTTACC AGACCACAGA CTTCTCCGGA ATCCGTAACA TCAGTTTCAT GGTGAAACGC 
ATAAGAATCA ATACAACTGC TGATGAGAAG GACCCTACAA ATCCTTTCCG TTTCCCAAAT 
ATTGGTGTGG AGAAGTTTCT GGAATTGAAT TCTGAGCAGA ATCATGATGA CTACTGTTTG 
GCCTATGTCT TCACAGACCG AGATTTTGAT GATGGCGTAC TTGGTCTGGC TTGGGTTGGA 
GCACCTTCAG GAAGCTCTGG AGGAATATGT GAAAAAAGTA AACTCTATTC AGATGGTAAG 
AAGAAGTCCT TAAACACTGG AATTATTACT GTTCAGAACT ATGGGTCTCA TGTACCTCCC 
AAAGTCTCTC ACATTACTTT TGCTCACGAA GTTGGACATA ACTTTGGATC CCCACATGAT 
TCTGGAACAG AGTGCACACC AGGAGAATCT AAGAATTTGG GTCAAAAAGA AAATGGCAAT 
TACATCATGT ATGCAAGAGC AACATCTGGG GACAAACTTA ACAACAATAA ATTCTCACTC 
TGTAGTATTA GAAATATAAG CCAAGTTCTT GAGAAGAAGA GAAACAACTG TTTTGTTGAA 
TCTGGCCAAC CTATTTGTGG AAATGGAATG GTAGAACAAG GTGAAGAATG TGATTGTGGC 
TATAGTGACC AGTGTAAAGA TGAATGCTGC TTCGATGCAA ATCAACCAGA GGGAAGAAAA 
TGCAAACTGA AACCTGGGAA ACAGTGCAGT CCAAGTCAAG GTCCTTGTTG TACAGCACAG 
TGTGCATTCA AGTCAAAGTC TGAGAAGTGT CGGGATGATT CAGACTGTGC AAGGGAAGGA 
ATATGTAATG GCTTCACAGC TCTCTGCCCA GCATCTGACC CTAAACCAAA CTTCACAGAC 
TGTAATAGGC ATACACAAGT GTGCATTAAT GGGCAATGTG CAGGTTCTAT CTGTGAGAAA 
TATGGCTTAG AGGAGTGTAC GTGTGCCAGT TCTGATGGCA AAGATGATAA AGAATTATGC 
CATGTATGCT GTATGAAGAA AATGGACCCA TCAACTTGTG CCAGTACAGG GTCTGTGCAG 
TGGAGTAGGC ACTTCAGTGG TCGAACCATC ACCCTGCAAC CTGGATCCCC TTGCAACGAT 
TTTAGAGGTT ACTGTGATGT TTTCATGCGG TGCAGATTAG TAGATGCTGA TGGTCCTCTA 
GCTAGGCTTA AAAAAGCAAT TTTTAGTCCA GAGCTCTATG AAAACATTGC TGAATGGATT 
GTGGCTCATT GGTGGGCAGT ATTACTTATG GGAATTGCTC TGATCATGCT AATGGCTGGA 
TTTATTAAGA TATGCAGTGT TCATACTCCA AGTAGTAATC CAAAGTTGCC TCCTCCTAAA 
CCACTTCCAG GCACTTTAAA GAGGAGGAGA CCTCCACAGC CCATTCAGCA ACCCCAGCGT 
CAGCGGCCCC GAGAGAGTTA TCAAATGGGA CACATGAGAC GCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024305586.1
CDS	340..2364
Translation	MKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQPIQQPQRQRPRESYQMGHMRR

Target ORF information:

RefSeq Version	XM_024449818.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024449818.1

ORF Insert Sequence:

ATGAAGAGGG ACACTTCCCT TTTCAGTGAT GAATTTAAAG TAGAAACATC AAATAAAGTA 
CTTGATTATG ATACCTCTCA TATTTACACT GGACATATTT ATGGTGAAGA AGGAAGTTTT 
AGCCATGGGT CTGTTATTGA TGGAAGATTT GAAGGATTCA TCCAGACTCG TGGTGGCACA 
TTTTATGTTG AGCCAGCAGA GAGATATATT AAAGACCGAA CTCTGCCATT TCACTCTGTC 
ATTTATCATG AAGATGATAT TAACTATCCC CATAAATACG GTCCTCAGGG GGGCTGTGCA 
GATCATTCAG TATTTGAAAG AATGAGGAAA TACCAGATGA CTGGTGTAGA GGAAGTAACA 
CAGATACCTC AAGAAGAACA TGCTGCTAAT GGTCCAGAAC TTCTGAGGAA AAAACGTACA 
ACTTCAGCTG AAAAAAATAC TTGTCAGCTT TATATTCAGA CTGATCATTT GTTCTTTAAA 
TATTACGGAA CACGAGAAGC TGTGATTGCC CAGATATCCA GTCATGTTAA AGCGATTGAT 
ACAATTTACC AGACCACAGA CTTCTCCGGA ATCCGTAACA TCAGTTTCAT GGTGAAACGC 
ATAAGAATCA ATACAACTGC TGATGAGAAG GACCCTACAA ATCCTTTCCG TTTCCCAAAT 
ATTGGTGTGG AGAAGTTTCT GGAATTGAAT TCTGAGCAGA ATCATGATGA CTACTGTTTG 
GCCTATGTCT TCACAGACCG AGATTTTGAT GATGGCGTAC TTGGTCTGGC TTGGGTTGGA 
GCACCTTCAG GAAGCTCTGG AGGAATATGT GAAAAAAGTA AACTCTATTC AGATGGTAAG 
AAGAAGTCCT TAAACACTGG AATTATTACT GTTCAGAACT ATGGGTCTCA TGTACCTCCC 
AAAGTCTCTC ACATTACTTT TGCTCACGAA GTTGGACATA ACTTTGGATC CCCACATGAT 
TCTGGAACAG AGTGCACACC AGGAGAATCT AAGAATTTGG GTCAAAAAGA AAATGGCAAT 
TACATCATGT ATGCAAGAGC AACATCTGGG GACAAACTTA ACAACAATAA ATTCTCACTC 
TGTAGTATTA GAAATATAAG CCAAGTTCTT GAGAAGAAGA GAAACAACTG TTTTGTTGAA 
TCTGGCCAAC CTATTTGTGG AAATGGAATG GTAGAACAAG GTGAAGAATG TGATTGTGGC 
TATAGTGACC AGTGTAAAGA TGAATGCTGC TTCGATGCAA ATCAACCAGA GGGAAGAAAA 
TGCAAACTGA AACCTGGGAA ACAGTGCAGT CCAAGTCAAG GTCCTTGTTG TACAGCACAG 
TGTGCATTCA AGTCAAAGTC TGAGAAGTGT CGGGATGATT CAGACTGTGC AAGGGAAGGA 
ATATGTAATG GCTTCACAGC TCTCTGCCCA GCATCTGACC CTAAACCAAA CTTCACAGAC 
TGTAATAGGC ATACACAAGT GTGCATTAAT GGGCAATGTG CAGGTTCTAT CTGTGAGAAA 
TATGGCTTAG AGGAGTGTAC GTGTGCCAGT TCTGATGGCA AAGATGATAA AGAATTATGC 
CATGTATGCT GTATGAAGAA AATGGACCCA TCAACTTGTG CCAGTACAGG GTCTGTGCAG 
TGGAGTAGGC ACTTCAGTGG TCGAACCATC ACCCTGCAAC CTGGATCCCC TTGCAACGAT 
TTTAGAGGTT ACTGTGATGT TTTCATGCGG TGCAGATTAG TAGATGCTGA TGGTCCTCTA 
GCTAGGCTTA AAAAAGCAAT TTTTAGTCCA GAGCTCTATG AAAACATTGC TGAATGGATT 
GTGGCTCATT GGTGGGCAGT ATTACTTATG GGAATTGCTC TGATCATGCT AATGGCTGGA 
TTTATTAAGA TATGCAGTGT TCATACTCCA AGTAGTAATC CAAAGTTGCC TCCTCCTAAA 
CCACTTCCAG GCACTTTAAA GAGGAGGAGA CCTCCACAGC CCATTCAGCA ACCCCAGCGT 
CAGCGGCCCC GAGAGAGTTA TCAAATGGGA CACATGAGAC GCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM10 ( XM_017021861.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877350.1 Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu85226
Clone ID Related Accession (Same CDS sequence)	XM_024449818.1 , XM_017021861.1
Accession Version	XM_017021861.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2025bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAGGG ACACTTCCCT TTTCAGTGAT GAATTTAAAG TAGAAACATC AAATAAAGTA 
CTTGATTATG ATACCTCTCA TATTTACACT GGACATATTT ATGGTGAAGA AGGAAGTTTT 
AGCCATGGGT CTGTTATTGA TGGAAGATTT GAAGGATTCA TCCAGACTCG TGGTGGCACA 
TTTTATGTTG AGCCAGCAGA GAGATATATT AAAGACCGAA CTCTGCCATT TCACTCTGTC 
ATTTATCATG AAGATGATAT TAACTATCCC CATAAATACG GTCCTCAGGG GGGCTGTGCA 
GATCATTCAG TATTTGAAAG AATGAGGAAA TACCAGATGA CTGGTGTAGA GGAAGTAACA 
CAGATACCTC AAGAAGAACA TGCTGCTAAT GGTCCAGAAC TTCTGAGGAA AAAACGTACA 
ACTTCAGCTG AAAAAAATAC TTGTCAGCTT TATATTCAGA CTGATCATTT GTTCTTTAAA 
TATTACGGAA CACGAGAAGC TGTGATTGCC CAGATATCCA GTCATGTTAA AGCGATTGAT 
ACAATTTACC AGACCACAGA CTTCTCCGGA ATCCGTAACA TCAGTTTCAT GGTGAAACGC 
ATAAGAATCA ATACAACTGC TGATGAGAAG GACCCTACAA ATCCTTTCCG TTTCCCAAAT 
ATTGGTGTGG AGAAGTTTCT GGAATTGAAT TCTGAGCAGA ATCATGATGA CTACTGTTTG 
GCCTATGTCT TCACAGACCG AGATTTTGAT GATGGCGTAC TTGGTCTGGC TTGGGTTGGA 
GCACCTTCAG GAAGCTCTGG AGGAATATGT GAAAAAAGTA AACTCTATTC AGATGGTAAG 
AAGAAGTCCT TAAACACTGG AATTATTACT GTTCAGAACT ATGGGTCTCA TGTACCTCCC 
AAAGTCTCTC ACATTACTTT TGCTCACGAA GTTGGACATA ACTTTGGATC CCCACATGAT 
TCTGGAACAG AGTGCACACC AGGAGAATCT AAGAATTTGG GTCAAAAAGA AAATGGCAAT 
TACATCATGT ATGCAAGAGC AACATCTGGG GACAAACTTA ACAACAATAA ATTCTCACTC 
TGTAGTATTA GAAATATAAG CCAAGTTCTT GAGAAGAAGA GAAACAACTG TTTTGTTGAA 
TCTGGCCAAC CTATTTGTGG AAATGGAATG GTAGAACAAG GTGAAGAATG TGATTGTGGC 
TATAGTGACC AGTGTAAAGA TGAATGCTGC TTCGATGCAA ATCAACCAGA GGGAAGAAAA 
TGCAAACTGA AACCTGGGAA ACAGTGCAGT CCAAGTCAAG GTCCTTGTTG TACAGCACAG 
TGTGCATTCA AGTCAAAGTC TGAGAAGTGT CGGGATGATT CAGACTGTGC AAGGGAAGGA 
ATATGTAATG GCTTCACAGC TCTCTGCCCA GCATCTGACC CTAAACCAAA CTTCACAGAC 
TGTAATAGGC ATACACAAGT GTGCATTAAT GGGCAATGTG CAGGTTCTAT CTGTGAGAAA 
TATGGCTTAG AGGAGTGTAC GTGTGCCAGT TCTGATGGCA AAGATGATAA AGAATTATGC 
CATGTATGCT GTATGAAGAA AATGGACCCA TCAACTTGTG CCAGTACAGG GTCTGTGCAG 
TGGAGTAGGC ACTTCAGTGG TCGAACCATC ACCCTGCAAC CTGGATCCCC TTGCAACGAT 
TTTAGAGGTT ACTGTGATGT TTTCATGCGG TGCAGATTAG TAGATGCTGA TGGTCCTCTA 
GCTAGGCTTA AAAAAGCAAT TTTTAGTCCA GAGCTCTATG AAAACATTGC TGAATGGATT 
GTGGCTCATT GGTGGGCAGT ATTACTTATG GGAATTGCTC TGATCATGCT AATGGCTGGA 
TTTATTAAGA TATGCAGTGT TCATACTCCA AGTAGTAATC CAAAGTTGCC TCCTCCTAAA 
CCACTTCCAG GCACTTTAAA GAGGAGGAGA CCTCCACAGC CCATTCAGCA ACCCCAGCGT 
CAGCGGCCCC GAGAGAGTTA TCAAATGGGA CACATGAGAC GCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877350.1
CDS	722..2746
Translation	MKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQPIQQPQRQRPRESYQMGHMRR

Target ORF information:

RefSeq Version	XM_017021861.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017021861.1

ORF Insert Sequence:

ATGAAGAGGG ACACTTCCCT TTTCAGTGAT GAATTTAAAG TAGAAACATC AAATAAAGTA 
CTTGATTATG ATACCTCTCA TATTTACACT GGACATATTT ATGGTGAAGA AGGAAGTTTT 
AGCCATGGGT CTGTTATTGA TGGAAGATTT GAAGGATTCA TCCAGACTCG TGGTGGCACA 
TTTTATGTTG AGCCAGCAGA GAGATATATT AAAGACCGAA CTCTGCCATT TCACTCTGTC 
ATTTATCATG AAGATGATAT TAACTATCCC CATAAATACG GTCCTCAGGG GGGCTGTGCA 
GATCATTCAG TATTTGAAAG AATGAGGAAA TACCAGATGA CTGGTGTAGA GGAAGTAACA 
CAGATACCTC AAGAAGAACA TGCTGCTAAT GGTCCAGAAC TTCTGAGGAA AAAACGTACA 
ACTTCAGCTG AAAAAAATAC TTGTCAGCTT TATATTCAGA CTGATCATTT GTTCTTTAAA 
TATTACGGAA CACGAGAAGC TGTGATTGCC CAGATATCCA GTCATGTTAA AGCGATTGAT 
ACAATTTACC AGACCACAGA CTTCTCCGGA ATCCGTAACA TCAGTTTCAT GGTGAAACGC 
ATAAGAATCA ATACAACTGC TGATGAGAAG GACCCTACAA ATCCTTTCCG TTTCCCAAAT 
ATTGGTGTGG AGAAGTTTCT GGAATTGAAT TCTGAGCAGA ATCATGATGA CTACTGTTTG 
GCCTATGTCT TCACAGACCG AGATTTTGAT GATGGCGTAC TTGGTCTGGC TTGGGTTGGA 
GCACCTTCAG GAAGCTCTGG AGGAATATGT GAAAAAAGTA AACTCTATTC AGATGGTAAG 
AAGAAGTCCT TAAACACTGG AATTATTACT GTTCAGAACT ATGGGTCTCA TGTACCTCCC 
AAAGTCTCTC ACATTACTTT TGCTCACGAA GTTGGACATA ACTTTGGATC CCCACATGAT 
TCTGGAACAG AGTGCACACC AGGAGAATCT AAGAATTTGG GTCAAAAAGA AAATGGCAAT 
TACATCATGT ATGCAAGAGC AACATCTGGG GACAAACTTA ACAACAATAA ATTCTCACTC 
TGTAGTATTA GAAATATAAG CCAAGTTCTT GAGAAGAAGA GAAACAACTG TTTTGTTGAA 
TCTGGCCAAC CTATTTGTGG AAATGGAATG GTAGAACAAG GTGAAGAATG TGATTGTGGC 
TATAGTGACC AGTGTAAAGA TGAATGCTGC TTCGATGCAA ATCAACCAGA GGGAAGAAAA 
TGCAAACTGA AACCTGGGAA ACAGTGCAGT CCAAGTCAAG GTCCTTGTTG TACAGCACAG 
TGTGCATTCA AGTCAAAGTC TGAGAAGTGT CGGGATGATT CAGACTGTGC AAGGGAAGGA 
ATATGTAATG GCTTCACAGC TCTCTGCCCA GCATCTGACC CTAAACCAAA CTTCACAGAC 
TGTAATAGGC ATACACAAGT GTGCATTAAT GGGCAATGTG CAGGTTCTAT CTGTGAGAAA 
TATGGCTTAG AGGAGTGTAC GTGTGCCAGT TCTGATGGCA AAGATGATAA AGAATTATGC 
CATGTATGCT GTATGAAGAA AATGGACCCA TCAACTTGTG CCAGTACAGG GTCTGTGCAG 
TGGAGTAGGC ACTTCAGTGG TCGAACCATC ACCCTGCAAC CTGGATCCCC TTGCAACGAT 
TTTAGAGGTT ACTGTGATGT TTTCATGCGG TGCAGATTAG TAGATGCTGA TGGTCCTCTA 
GCTAGGCTTA AAAAAGCAAT TTTTAGTCCA GAGCTCTATG AAAACATTGC TGAATGGATT 
GTGGCTCATT GGTGGGCAGT ATTACTTATG GGAATTGCTC TGATCATGCT AATGGCTGGA 
TTTATTAAGA TATGCAGTGT TCATACTCCA AGTAGTAATC CAAAGTTGCC TCCTCCTAAA 
CCACTTCCAG GCACTTTAAA GAGGAGGAGA CCTCCACAGC CCATTCAGCA ACCCCAGCGT 
CAGCGGCCCC GAGAGAGTTA TCAAATGGGA CACATGAGAC GCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM10 ( NM_001320570.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307499.1 Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu48053
Clone ID Related Accession (Same CDS sequence)	NM_001320570.1 , NM_001320570.2
Accession Version	NM_001320570.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 10 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC091046.2 and AC018904.6. On Mar 1, 2016 this sequence version replaced XM_005254117.2. Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The encoded isoform (2) is shorter than isoform 1. This isoform (2) may undergo proteolytic processing similar to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.249068.1, SRR1660803.42914.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTTGC TGAGAGTGTT AATTCTGCTC CTCTCCTGGG CGGCGGGGAT GGGAGGTCAG 
TATGGGAATC CTTTAAATAA ATATATCAGA CATTATGAAG GATTATCTTA CAATGTGGAT 
TCATTACACC AAAAACACCA GCGTGCCAAA AGAGCAGTCT CACATGAAGA CCAATTTTTA 
CGTCTAGATT TCCATGCCCA TGGAAGACAT TTCAACCTAC GAATGAAGAG GGACACTTCC 
CTTTTCAGTG ATGAATTTAA AGTAGAAACA TCAAATAAAG TACTTGATTA TGATACCTCT 
CATATTTACA CTGGACATAT TTATGGTGAA GAAGGAAGTT TTAGCCATGG GTCTGTTATT 
GATGGAAGAT TTGAAGGATT CATCCAGACT CGTGGTGGCA CATTTTATGT TGAGCCAGCA 
GAGAGATATA TTAAAGACCG AACTCTGCCA TTTCACTCTG TCATTTATCA TGAAGATGAT 
ATTAACTATC CCCATAAATA CGGTCCTCAG GGGGGCTGTG CAGATCATTC AGTATTTGAA 
AGAATGAGGA AATACCAGAT GACTGGTGTA GAGGAAGTAA CACAGATACC TCAAGAAGAA 
CATGCTGCTA ATGGTCCAGA ACTTCTGAGG AAAAAACGTA CAACTTCAGC TGAAAAAAAT 
ACTTGTCAGC TTTATATTCA GACTGATCAT TTGTTCTTTA AATATTACGG AACACGAGAA 
GCTGTGATTG CCCAGATCAA TACAACTGCT GATGAGAAGG ACCCTACAAA TCCTTTCCGT 
TTCCCAAATA TTGGTGTGGA GAAGTTTCTG GAATTGAATT CTGAGCAGAA TCATGATGAC 
TACTGTTTGG CCTATGTCTT CACAGACCGA GATTTTGATG ATGGCGTACT TGGTCTGGCT 
TGGGTTGGAG CACCTTCAGG AAGCTCTGGA GGAATATGTG AAAAAAGTAA ACTCTATTCA 
GATGGTAAGA AGAAGTCCTT AAACACTGGA ATTATTACTG TTCAGAACTA TGGGTCTCAT 
GTACCTCCCA AAGTCTCTCA CATTACTTTT GCTCACGAAG TTGGACATAA CTTTGGATCC 
CCACATGATT CTGGAACAGA GTGCACACCA GGAGAATCTA AGAATTTGGG TCAAAAAGAA 
AATGGCAATT ACATCATGTA TGCAAGAGCA ACATCTGGGG ACAAACTTAA CAACAATAAA 
TTCTCACTCT GTAGTATTAG AAATATAAGC CAAGTTCTTG AGAAGAAGAG AAACAACTGT 
TTTGTTGAAT CTGGCCAACC TATTTGTGGA AATGGAATGG TAGAACAAGG TGAAGAATGT 
GATTGTGGCT ATAGTGACCA GTGTAAAGAT GAATGCTGCT TCGATGCAAA TCAACCAGAG 
GGAAGAAAAT GCAAACTGAA ACCTGGGAAA CAGTGCAGTC CAAGTCAAGG TCCTTGTTGT 
ACAGCACAGT GTGCATTCAA GTCAAAGTCT GAGAAGTGTC GGGATGATTC AGACTGTGCA 
AGGGAAGGAA TATGTAATGG CTTCACAGCT CTCTGCCCAG CATCTGACCC TAAACCAAAC 
TTCACAGACT GTAATAGGCA TACACAAGTG TGCATTAATG GGCAATGTGC AGGTTCTATC 
TGTGAGAAAT ATGGCTTAGA GGAGTGTACG TGTGCCAGTT CTGATGGCAA AGATGATAAA 
GAATTATGCC ATGTATGCTG TATGAAGAAA ATGGACCCAT CAACTTGTGC CAGTACAGGG 
TCTGTGCAGT GGAGTAGGCA CTTCAGTGGT CGAACCATCA CCCTGCAACC TGGATCCCCT 
TGCAACGATT TTAGAGGTTA CTGTGATGTT TTCATGCGGT GCAGATTAGT AGATGCTGAT 
GGTCCTCTAG CTAGGCTTAA AAAAGCAATT TTTAGTCCAG AGCTCTATGA AAACATTGCT 
GAATGGATTG TGGCTCATTG GTGGGCAGTA TTACTTATGG GAATTGCTCT GATCATGCTA 
ATGGCTGGAT TTATTAAGAT ATGCAGTGTT CATACTCCAA GTAGTAATCC AAAGTTGCCT 
CCTCCTAAAC CACTTCCAGG CACTTTAAAG AGGAGGAGAC CTCCACAGCC CATTCAGCAA 
CCCCAGCGTC AGCGGCCCCG AGAGAGTTAT CAAATGGGAC ACATGAGACG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307499.1
CDS	445..2598
Translation	MVLLRVLILLLSWAAGMGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQPIQQPQRQRPRESYQMGHMRR

Target ORF information:

RefSeq Version	NM_001320570.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001320570.1

ORF Insert Sequence:

ATGGTGTTGC TGAGAGTGTT AATTCTGCTC CTCTCCTGGG CGGCGGGGAT GGGAGGTCAG 
TATGGGAATC CTTTAAATAA ATATATCAGA CATTATGAAG GATTATCTTA CAATGTGGAT 
TCATTACACC AAAAACACCA GCGTGCCAAA AGAGCAGTCT CACATGAAGA CCAATTTTTA 
CGTCTAGATT TCCATGCCCA TGGAAGACAT TTCAACCTAC GAATGAAGAG GGACACTTCC 
CTTTTCAGTG ATGAATTTAA AGTAGAAACA TCAAATAAAG TACTTGATTA TGATACCTCT 
CATATTTACA CTGGACATAT TTATGGTGAA GAAGGAAGTT TTAGCCATGG GTCTGTTATT 
GATGGAAGAT TTGAAGGATT CATCCAGACT CGTGGTGGCA CATTTTATGT TGAGCCAGCA 
GAGAGATATA TTAAAGACCG AACTCTGCCA TTTCACTCTG TCATTTATCA TGAAGATGAT 
ATTAACTATC CCCATAAATA CGGTCCTCAG GGGGGCTGTG CAGATCATTC AGTATTTGAA 
AGAATGAGGA AATACCAGAT GACTGGTGTA GAGGAAGTAA CACAGATACC TCAAGAAGAA 
CATGCTGCTA ATGGTCCAGA ACTTCTGAGG AAAAAACGTA CAACTTCAGC TGAAAAAAAT 
ACTTGTCAGC TTTATATTCA GACTGATCAT TTGTTCTTTA AATATTACGG AACACGAGAA 
GCTGTGATTG CCCAGATCAA TACAACTGCT GATGAGAAGG ACCCTACAAA TCCTTTCCGT 
TTCCCAAATA TTGGTGTGGA GAAGTTTCTG GAATTGAATT CTGAGCAGAA TCATGATGAC 
TACTGTTTGG CCTATGTCTT CACAGACCGA GATTTTGATG ATGGCGTACT TGGTCTGGCT 
TGGGTTGGAG CACCTTCAGG AAGCTCTGGA GGAATATGTG AAAAAAGTAA ACTCTATTCA 
GATGGTAAGA AGAAGTCCTT AAACACTGGA ATTATTACTG TTCAGAACTA TGGGTCTCAT 
GTACCTCCCA AAGTCTCTCA CATTACTTTT GCTCACGAAG TTGGACATAA CTTTGGATCC 
CCACATGATT CTGGAACAGA GTGCACACCA GGAGAATCTA AGAATTTGGG TCAAAAAGAA 
AATGGCAATT ACATCATGTA TGCAAGAGCA ACATCTGGGG ACAAACTTAA CAACAATAAA 
TTCTCACTCT GTAGTATTAG AAATATAAGC CAAGTTCTTG AGAAGAAGAG AAACAACTGT 
TTTGTTGAAT CTGGCCAACC TATTTGTGGA AATGGAATGG TAGAACAAGG TGAAGAATGT 
GATTGTGGCT ATAGTGACCA GTGTAAAGAT GAATGCTGCT TCGATGCAAA TCAACCAGAG 
GGAAGAAAAT GCAAACTGAA ACCTGGGAAA CAGTGCAGTC CAAGTCAAGG TCCTTGTTGT 
ACAGCACAGT GTGCATTCAA GTCAAAGTCT GAGAAGTGTC GGGATGATTC AGACTGTGCA 
AGGGAAGGAA TATGTAATGG CTTCACAGCT CTCTGCCCAG CATCTGACCC TAAACCAAAC 
TTCACAGACT GTAATAGGCA TACACAAGTG TGCATTAATG GGCAATGTGC AGGTTCTATC 
TGTGAGAAAT ATGGCTTAGA GGAGTGTACG TGTGCCAGTT CTGATGGCAA AGATGATAAA 
GAATTATGCC ATGTATGCTG TATGAAGAAA ATGGACCCAT CAACTTGTGC CAGTACAGGG 
TCTGTGCAGT GGAGTAGGCA CTTCAGTGGT CGAACCATCA CCCTGCAACC TGGATCCCCT 
TGCAACGATT TTAGAGGTTA CTGTGATGTT TTCATGCGGT GCAGATTAGT AGATGCTGAT 
GGTCCTCTAG CTAGGCTTAA AAAAGCAATT TTTAGTCCAG AGCTCTATGA AAACATTGCT 
GAATGGATTG TGGCTCATTG GTGGGCAGTA TTACTTATGG GAATTGCTCT GATCATGCTA 
ATGGCTGGAT TTATTAAGAT ATGCAGTGTT CATACTCCAA GTAGTAATCC AAAGTTGCCT 
CCTCCTAAAC CACTTCCAGG CACTTTAAAG AGGAGGAGAC CTCCACAGCC CATTCAGCAA 
CCCCAGCGTC AGCGGCCCCG AGAGAGTTAT CAAATGGGAC ACATGAGACG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM10 ( NM_001320570.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307499.1 Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 2, mRNA.

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CloneID	OHu48053
Clone ID Related Accession (Same CDS sequence)	NM_001320570.1 , NM_001320570.2
Accession Version	NM_001320570.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 10 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC091046.2 and AC018904.6. On May 31, 2019 this sequence version replaced NM_001320570.1. Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The encoded isoform (2) is shorter than isoform 1. This isoform (2) may undergo proteolytic processing similar to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.265768.1, SRR1660803.249068.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTTGC TGAGAGTGTT AATTCTGCTC CTCTCCTGGG CGGCGGGGAT GGGAGGTCAG 
TATGGGAATC CTTTAAATAA ATATATCAGA CATTATGAAG GATTATCTTA CAATGTGGAT 
TCATTACACC AAAAACACCA GCGTGCCAAA AGAGCAGTCT CACATGAAGA CCAATTTTTA 
CGTCTAGATT TCCATGCCCA TGGAAGACAT TTCAACCTAC GAATGAAGAG GGACACTTCC 
CTTTTCAGTG ATGAATTTAA AGTAGAAACA TCAAATAAAG TACTTGATTA TGATACCTCT 
CATATTTACA CTGGACATAT TTATGGTGAA GAAGGAAGTT TTAGCCATGG GTCTGTTATT 
GATGGAAGAT TTGAAGGATT CATCCAGACT CGTGGTGGCA CATTTTATGT TGAGCCAGCA 
GAGAGATATA TTAAAGACCG AACTCTGCCA TTTCACTCTG TCATTTATCA TGAAGATGAT 
ATTAACTATC CCCATAAATA CGGTCCTCAG GGGGGCTGTG CAGATCATTC AGTATTTGAA 
AGAATGAGGA AATACCAGAT GACTGGTGTA GAGGAAGTAA CACAGATACC TCAAGAAGAA 
CATGCTGCTA ATGGTCCAGA ACTTCTGAGG AAAAAACGTA CAACTTCAGC TGAAAAAAAT 
ACTTGTCAGC TTTATATTCA GACTGATCAT TTGTTCTTTA AATATTACGG AACACGAGAA 
GCTGTGATTG CCCAGATCAA TACAACTGCT GATGAGAAGG ACCCTACAAA TCCTTTCCGT 
TTCCCAAATA TTGGTGTGGA GAAGTTTCTG GAATTGAATT CTGAGCAGAA TCATGATGAC 
TACTGTTTGG CCTATGTCTT CACAGACCGA GATTTTGATG ATGGCGTACT TGGTCTGGCT 
TGGGTTGGAG CACCTTCAGG AAGCTCTGGA GGAATATGTG AAAAAAGTAA ACTCTATTCA 
GATGGTAAGA AGAAGTCCTT AAACACTGGA ATTATTACTG TTCAGAACTA TGGGTCTCAT 
GTACCTCCCA AAGTCTCTCA CATTACTTTT GCTCACGAAG TTGGACATAA CTTTGGATCC 
CCACATGATT CTGGAACAGA GTGCACACCA GGAGAATCTA AGAATTTGGG TCAAAAAGAA 
AATGGCAATT ACATCATGTA TGCAAGAGCA ACATCTGGGG ACAAACTTAA CAACAATAAA 
TTCTCACTCT GTAGTATTAG AAATATAAGC CAAGTTCTTG AGAAGAAGAG AAACAACTGT 
TTTGTTGAAT CTGGCCAACC TATTTGTGGA AATGGAATGG TAGAACAAGG TGAAGAATGT 
GATTGTGGCT ATAGTGACCA GTGTAAAGAT GAATGCTGCT TCGATGCAAA TCAACCAGAG 
GGAAGAAAAT GCAAACTGAA ACCTGGGAAA CAGTGCAGTC CAAGTCAAGG TCCTTGTTGT 
ACAGCACAGT GTGCATTCAA GTCAAAGTCT GAGAAGTGTC GGGATGATTC AGACTGTGCA 
AGGGAAGGAA TATGTAATGG CTTCACAGCT CTCTGCCCAG CATCTGACCC TAAACCAAAC 
TTCACAGACT GTAATAGGCA TACACAAGTG TGCATTAATG GGCAATGTGC AGGTTCTATC 
TGTGAGAAAT ATGGCTTAGA GGAGTGTACG TGTGCCAGTT CTGATGGCAA AGATGATAAA 
GAATTATGCC ATGTATGCTG TATGAAGAAA ATGGACCCAT CAACTTGTGC CAGTACAGGG 
TCTGTGCAGT GGAGTAGGCA CTTCAGTGGT CGAACCATCA CCCTGCAACC TGGATCCCCT 
TGCAACGATT TTAGAGGTTA CTGTGATGTT TTCATGCGGT GCAGATTAGT AGATGCTGAT 
GGTCCTCTAG CTAGGCTTAA AAAAGCAATT TTTAGTCCAG AGCTCTATGA AAACATTGCT 
GAATGGATTG TGGCTCATTG GTGGGCAGTA TTACTTATGG GAATTGCTCT GATCATGCTA 
ATGGCTGGAT TTATTAAGAT ATGCAGTGTT CATACTCCAA GTAGTAATCC AAAGTTGCCT 
CCTCCTAAAC CACTTCCAGG CACTTTAAAG AGGAGGAGAC CTCCACAGCC CATTCAGCAA 
CCCCAGCGTC AGCGGCCCCG AGAGAGTTAT CAAATGGGAC ACATGAGACG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307499.1
CDS	174..2327
Translation	MVLLRVLILLLSWAAGMGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQPIQQPQRQRPRESYQMGHMRR

Target ORF information:

RefSeq Version	NM_001320570.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001320570.2

ORF Insert Sequence:

ATGGTGTTGC TGAGAGTGTT AATTCTGCTC CTCTCCTGGG CGGCGGGGAT GGGAGGTCAG 
TATGGGAATC CTTTAAATAA ATATATCAGA CATTATGAAG GATTATCTTA CAATGTGGAT 
TCATTACACC AAAAACACCA GCGTGCCAAA AGAGCAGTCT CACATGAAGA CCAATTTTTA 
CGTCTAGATT TCCATGCCCA TGGAAGACAT TTCAACCTAC GAATGAAGAG GGACACTTCC 
CTTTTCAGTG ATGAATTTAA AGTAGAAACA TCAAATAAAG TACTTGATTA TGATACCTCT 
CATATTTACA CTGGACATAT TTATGGTGAA GAAGGAAGTT TTAGCCATGG GTCTGTTATT 
GATGGAAGAT TTGAAGGATT CATCCAGACT CGTGGTGGCA CATTTTATGT TGAGCCAGCA 
GAGAGATATA TTAAAGACCG AACTCTGCCA TTTCACTCTG TCATTTATCA TGAAGATGAT 
ATTAACTATC CCCATAAATA CGGTCCTCAG GGGGGCTGTG CAGATCATTC AGTATTTGAA 
AGAATGAGGA AATACCAGAT GACTGGTGTA GAGGAAGTAA CACAGATACC TCAAGAAGAA 
CATGCTGCTA ATGGTCCAGA ACTTCTGAGG AAAAAACGTA CAACTTCAGC TGAAAAAAAT 
ACTTGTCAGC TTTATATTCA GACTGATCAT TTGTTCTTTA AATATTACGG AACACGAGAA 
GCTGTGATTG CCCAGATCAA TACAACTGCT GATGAGAAGG ACCCTACAAA TCCTTTCCGT 
TTCCCAAATA TTGGTGTGGA GAAGTTTCTG GAATTGAATT CTGAGCAGAA TCATGATGAC 
TACTGTTTGG CCTATGTCTT CACAGACCGA GATTTTGATG ATGGCGTACT TGGTCTGGCT 
TGGGTTGGAG CACCTTCAGG AAGCTCTGGA GGAATATGTG AAAAAAGTAA ACTCTATTCA 
GATGGTAAGA AGAAGTCCTT AAACACTGGA ATTATTACTG TTCAGAACTA TGGGTCTCAT 
GTACCTCCCA AAGTCTCTCA CATTACTTTT GCTCACGAAG TTGGACATAA CTTTGGATCC 
CCACATGATT CTGGAACAGA GTGCACACCA GGAGAATCTA AGAATTTGGG TCAAAAAGAA 
AATGGCAATT ACATCATGTA TGCAAGAGCA ACATCTGGGG ACAAACTTAA CAACAATAAA 
TTCTCACTCT GTAGTATTAG AAATATAAGC CAAGTTCTTG AGAAGAAGAG AAACAACTGT 
TTTGTTGAAT CTGGCCAACC TATTTGTGGA AATGGAATGG TAGAACAAGG TGAAGAATGT 
GATTGTGGCT ATAGTGACCA GTGTAAAGAT GAATGCTGCT TCGATGCAAA TCAACCAGAG 
GGAAGAAAAT GCAAACTGAA ACCTGGGAAA CAGTGCAGTC CAAGTCAAGG TCCTTGTTGT 
ACAGCACAGT GTGCATTCAA GTCAAAGTCT GAGAAGTGTC GGGATGATTC AGACTGTGCA 
AGGGAAGGAA TATGTAATGG CTTCACAGCT CTCTGCCCAG CATCTGACCC TAAACCAAAC 
TTCACAGACT GTAATAGGCA TACACAAGTG TGCATTAATG GGCAATGTGC AGGTTCTATC 
TGTGAGAAAT ATGGCTTAGA GGAGTGTACG TGTGCCAGTT CTGATGGCAA AGATGATAAA 
GAATTATGCC ATGTATGCTG TATGAAGAAA ATGGACCCAT CAACTTGTGC CAGTACAGGG 
TCTGTGCAGT GGAGTAGGCA CTTCAGTGGT CGAACCATCA CCCTGCAACC TGGATCCCCT 
TGCAACGATT TTAGAGGTTA CTGTGATGTT TTCATGCGGT GCAGATTAGT AGATGCTGAT 
GGTCCTCTAG CTAGGCTTAA AAAAGCAATT TTTAGTCCAG AGCTCTATGA AAACATTGCT 
GAATGGATTG TGGCTCATTG GTGGGCAGTA TTACTTATGG GAATTGCTCT GATCATGCTA 
ATGGCTGGAT TTATTAAGAT ATGCAGTGTT CATACTCCAA GTAGTAATCC AAAGTTGCCT 
CCTCCTAAAC CACTTCCAGG CACTTTAAAG AGGAGGAGAC CTCCACAGCC CATTCAGCAA 
CCCCAGCGTC AGCGGCCCCG AGAGAGTTAT CAAATGGGAC ACATGAGACG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

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ADAM10 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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