Gene Symbol | TUBA1B |
Entrez Gene ID | 10376 |
Full Name | tubulin alpha 1b |
Synonyms | K-ALPHA-1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » TUBA1B cDNA ORF clone
gRNAs
Gene Symbol | TUBA1B |
Entrez Gene ID | 10376 |
Full Name | tubulin alpha 1b |
Synonyms | K-ALPHA-1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_006082.2 | NP_006073.2 | tubulin alpha-1B chain |
NM_006082.3 | NP_006073.2 | tubulin alpha-1B chain |
Pan troglodytes (chimpanzee) | TUBA1B | NP_001029267.1 |
TUBA1B | XP_001108691.1 | |
Bos taurus (cattle) | TUBA1B | NP_001108328.1 |
Mus musculus (house mouse) | Tuba1b | NP_035784.1 |
Caenorhabditis elegans (roundworm) | tba-9 | NP_508555.2 |
Canis lupus familiaris (dog) | LOC610636 | XP_005640747.1 |
Danio rerio (zebrafish) | tuba2 | NP_998195.1 |
Homo sapiens (human) | TUBA1B | NP_006073.2 |
Xenopus tropicalis (tropical clawed frog) | tuba4a | NP_001107705.1 |
Gallus gallus (chicken) | TUBAL3 | NP_001264280.1 |
Mobility and Core-Protein Binding Patterns of Disordered C-Terminal Tails in ?-Tubulin Isotypes.
Laurin Y, Eyer J, Robert CH, Prevost C, Sacquin-Mora S
Biochemistry56(12)1746-1756(2017 03)
Identification of crucial genes related to postmenopausal osteoporosis using gene expression profiling.
Ma M, Chen X, Lu L, Yuan F, Zeng W, Luo S, Yin F, Cai J
Aging clinical and experimental research28(6)1067-1074(2016 Dec)
The low molecular weight fraction of commercial human serum albumin induces acetylation of ?-tubulin and reduces transcytosis in retinal endothelial cells.
Thomas GW, Rael LT, Hausburg M, Frederick ED, Brody E, Bar-Or D
Biochemical and biophysical research communications478(4)1780-5(2016 09)
New potential peptide therapeutics perturbing CK1?/?-tubulin interaction.
Kr?ger M, Kalbacher H, Kastritis PL, Bischof J, Barth H, Henne-Bruns D, Vorgias C, Sarno S, Pinna LA, Knippschild U
Cancer letters375(2)375-383(2016 Jun)
Regulation of SIRT2-dependent ?-tubulin deacetylation by cellular NAD levels.
Skoge RH, D?lle C, Ziegler M
DNA repair2333-8(2014 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The C-terminal tail from the tubulin beta I isotype, but not the beta III isotype, formed contacts in the putative binding site of a recently discovered antineoplastic peptide that disrupts microtubule formation in glioma cells.
Title: Mobility and Core-Protein Binding Patterns of Disordered C-Terminal Tails in ?-Tubulin Isotypes.
TUBA1B/ESR1 gene interaction might play pivotal roles in the occurrence and development of Postmenopausal Osteoporosis.
Title: Identification of crucial genes related to postmenopausal osteoporosis using gene expression profiling.
Data show that retinal endothelial cells (HREC) treated with low molecular weight fraction of commercial 5% human serum albumin (LMWF5A) exhibit a rapid increase in the amount and distribution of acetylated alpha-tubulin.
Title: The low molecular weight fraction of commercial human serum albumin induces acetylation of ?-tubulin and reduces transcytosis in retinal endothelial cells.
Taken together our data provide valuable information regarding the interaction of CK1delta and a-tubulin and a novel approach for the development of pharmacological tools to inhibit proliferation of cancer cells.
Title: New potential peptide therapeutics perturbing CK1?/?-tubulin interaction.
NAD-dependent regulation of alpha-tubulin acetylation is mediated by SIRT2.
Title: Regulation of SIRT2-dependent ?-tubulin deacetylation by cellular NAD levels.
The following TUBA1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TUBA1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
Online Only Promotion
Up to 50% OFF! Starting
from $49/clone
CloneID | OHu11371![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_006082.2 , NM_006082.3 | |
Accession Version | NM_006082.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-12-26 | |
Organism | Homo sapiens(human) | |
Product | tubulin alpha-1B chain | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF979331.1, AK098635.1 and BC006481.1. On Jan 4, 2005 this sequence version replaced NM_006082.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK026632.1, BC030820.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCGTGAGT GCATCTCCAT CCACGTTGGC CAGGCTGGTG TCCAGATTGG CAATGCCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_006073.2 |
CDS | 222..1577 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCGTGAGT GCATCTCCAT CCACGTTGGC CAGGCTGGTG TCCAGATTGG CAATGCCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu11371![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_006082.2 , NM_006082.3 | |
Accession Version | NM_006082.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-06 | |
Organism | Homo sapiens(human) | |
Product | tubulin alpha-1B chain | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF979331.1, AK098635.1 and BC006481.1. On Nov 23, 2018 this sequence version replaced NM_006082.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK026516.1, AK026632.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000336023.9/ ENSP00000336799.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGCGTGAGT GCATCTCCAT CCACGTTGGC CAGGCTGGTG TCCAGATTGG CAATGCCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_006073.2 |
CDS | 96..1451 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCGTGAGT GCATCTCCAT CCACGTTGGC CAGGCTGGTG TCCAGATTGG CAATGCCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mobility and Core-Protein Binding Patterns of Disordered C-Terminal Tails in ?-Tubulin Isotypes. |
Identification of crucial genes related to postmenopausal osteoporosis using gene expression profiling. |
The low molecular weight fraction of commercial human serum albumin induces acetylation of ?-tubulin and reduces transcytosis in retinal endothelial cells. |
New potential peptide therapeutics perturbing CK1?/?-tubulin interaction. |
Regulation of SIRT2-dependent ?-tubulin deacetylation by cellular NAD levels. |