Gene Symbol | RNF187 |
Entrez Gene ID | 149603 |
Full Name | ring finger protein 187 |
Synonyms | RACO-1,RACO1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » RNF187 cDNA ORF clone
gRNAs
Gene Symbol | RNF187 |
Entrez Gene ID | 149603 |
Full Name | ring finger protein 187 |
Synonyms | RACO-1,RACO1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001010858.2 | NP_001010858.2 | E3 ubiquitin-protein ligase RNF187 |
NM_001010858.3 | NP_001010858.2 | E3 ubiquitin-protein ligase RNF187 |
RNF187 is Downregulated Following NF-?B Inhibition in Late Erythroblasts.
Forster L, Finlayson J, Ghassemifar R
Biochemical genetics54(5)714-21(2016 Oct)
Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.
Chimusa ER, Zaitlen N, Daya M, M?ller M, van Helden PD, Mulder NJ, Price AL, Hoal EG
Human molecular genetics23(3)796-809(2014 Feb)
Arginine methylation of the c-Jun coactivator RACO-1 is required for c-Jun/AP-1 activation.
Davies CC, Chakraborty A, Diefenbacher ME, Skehel M, Behrens A
The EMBO journal32(11)1556-67(2013 May)
Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation.
Davies CC, Chakraborty A, Cipriani F, Haigh K, Haigh JJ, Behrens A
Nature cell biology12(10)963-72(2010 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Arginine methylation of RACO-1 is required for efficient transcriptional activation by c-Jun/AP-1 and thus identify PRMT1 as an important regulator of c-Jun/AP-1 function.
Title: Arginine methylation of the c-Jun coactivator RACO-1 is required for c-Jun/AP-1 activation.
The RACO-1(RING domain AP-1 co-activator-1) is a co-activator that links c-Jun to growth factor signalling and is essential for AP-1 function in proliferation
Title: Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation.
The following RNF187 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RNF187 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu15575 | |
Clone ID Related Accession (Same CDS sequence) | NM_001010858.2 , NM_001010858.3 | |
Accession Version | NM_001010858.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 708bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | E3 ubiquitin-protein ligase RNF187 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI551408.1, BC012758.2 and AL139288.15. On Aug 20, 2009 this sequence version replaced NM_001010858.1. Sequence Note: The annotated protein is predicted to be translated from a non-AUG start codon based on cross-species sequence conservation, and includes a RING domain that would not be present if translation were to initiate from the first in-frame AUG. This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC012758.2, SRR1163655.116643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | CTGGCGCTCC CTGCGGGCCC CGCCGAGGCC GCCTGCGCCC TGTGCCAGCG CGCGCCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001010858.2 |
CDS | 123..830 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | CTGGCGCTCC CTGCGGGCCC CGCCGAGGCC GCCTGCGCCC TGTGCCAGCG CGCGCCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu15575 | |
Clone ID Related Accession (Same CDS sequence) | NM_001010858.2 , NM_001010858.3 | |
Accession Version | NM_001010858.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 708bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-06 | |
Organism | Homo sapiens(human) | |
Product | E3 ubiquitin-protein ligase RNF187 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI551408.1, BC012758.2 and AL139288.15. On Nov 23, 2018 this sequence version replaced NM_001010858.2. Sequence Note: The annotated protein is predicted to be translated from a non-AUG start codon based on cross-species sequence conservation, and includes a RING domain that would not be present if translation were to initiate from the first in-frame AUG. This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: ERR279862.4775.1, BC012758.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: inferred from conservation RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | CTGGCGCTCC CTGCGGGCCC CGCCGAGGCC GCCTGCGCCC TGTGCCAGCG CGCGCCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001010858.2 |
CDS | 108..815 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | CTGGCGCTCC CTGCGGGCCC CGCCGAGGCC GCCTGCGCCC TGTGCCAGCG CGCGCCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RNF187 is Downregulated Following NF-?B Inhibition in Late Erythroblasts. |
Genome-wide association study of ancestry-specific TB risk in the South African Coloured population. |
Arginine methylation of the c-Jun coactivator RACO-1 is required for c-Jun/AP-1 activation. |
Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation. |