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RAB3GAP2 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol RAB3GAP2
Entrez Gene ID 25782
Full Name RAB3 GTPase activating non-catalytic protein subunit 2
Synonyms RAB3-GAP150,RAB3GAP150,SPG69,WARBM2,p150
General protein information
Preferred Names

RAB3 GTPase activating non-catalytic protein subunit 2

Names

rab3 GTPase-activating protein non-catalytic subunit
RAB3 GTPase activating protein subunit 2 (non-catalytic)
RGAP-iso
rab3 GTPase-activating protein 150 kDa subunit
rab3-GAP p150
rab3-GAP regulatory subunit
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

1

1q41
Summary The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009].
Disorder MIM:

609275

Disorder Html: Martsolf syndrome, 212720 (3); Warburg micro syndrome 2, 614225 (3)

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_012414.3 NP_036546.2 rab3 GTPase-activating protein non-catalytic subunit
NM_012414.4 NP_036546.2 rab3 GTPase-activating protein non-catalytic subunit

Pathways from BioSystems


Homologies


Rattus norvegicus (Norway rat) Rab3gap2 NP_001035244.2
Pan troglodytes (chimpanzee) RAB3GAP2 XP_514211.2
RAB3GAP2 XP_001103011.1
Bos taurus (cattle) RAB3GAP2 NP_001179128.1
Gallus gallus (chicken) RAB3GAP2 NP_001157272.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP001533 XP_551287.4
Oryza sativa (rice) Os09g0315800 NP_001062848.1
Xenopus tropicalis (tropical clawed frog) rab3gap2 NP_001120595.1
Homo sapiens (human) RAB3GAP2 NP_036546.2
Canis lupus familiaris (dog) RAB3GAP2 XP_536122.2
Danio rerio (zebrafish) rab3gap2 NP_001004528.1
Mus musculus (house mouse) Rab3gap2 NP_001157226.1
Arabidopsis thaliana (thale cress) AT3G14910 NP_188109.1
Drosophila melanogaster (fruit fly) rab3-GAP NP_609544.2

Gene Ontology


Bibliography

Related articles in PubMed

The RAB GTPase RAB18 modulates macroautophagy and proteostasis.
Feldmann A, Bekbulat F, Huesmann H, Ulbrich S, Tatzelt J, Behl C, Kern A
Biochemical and biophysical research communications486(3)738-743(2017 05)

FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.
Rasnitsyn A, Doucette L, Seifi M, Footz T, Raymond V, Walter MA
PloS one12(6)e0178518(2017)

RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy.
Spang N, Feldmann A, Huesmann H, Bekbulat F, Schmitt V, Hiebel C, Koziollek-Drechsler I, Clement AM, Moosmann B, Jung J, Behrends C, Dikic I, Kern A, Behl C
Autophagy10(12)2297-309(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

RAB18 modulates macroautophagy and proteostasis, and is dependent on activity of RAB3GAP1 and RAB3GAP2.
Title: The RAB GTPase RAB18 modulates macroautophagy and proteostasis.

show that FOXC1 regulates the expression of RAB3GAP1, RAB3GAP2 and SNAP25
Title: FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.

Rab18 and a Rab18 GEF complex of Rab3GAP1 and Rab3GAP2 have roles in the endoplasmic reticulum structure
Title: Rab18 and a Rab18 GEF complex are required for normal ER structure.

RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy
Title: RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy.

One-hundred and forty-four Micro and nine Martsolf families were investigated, identifying mutations in RAB3GAP1 in 41% of cases, mutations in RAB3GAP2 in 7% of cases, and mutations in RAB18 in 5% of cases
Title: Mutation spectrum in RAB3GAP1, RAB3GAP2, and RAB18 and genotype-phenotype correlations in warburg micro syndrome and Martsolf syndrome.

The following RAB3GAP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAB3GAP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu22188 NM_012414.4
Latest version!		 Homo sapiens RAB3 GTPase activating non-catalytic protein subunit 2 (RAB3GAP2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $519.50-$727.30
$1039.00
View Old Accession Versions >>
OHu22188 NM_012414.3 Homo sapiens RAB3 GTPase activating non-catalytic protein subunit 2 (RAB3GAP2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $519.50-$727.30
$1039.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu22188
Clone ID Related Accession (Same CDS sequence) NM_012414.3 , NM_012414.4
Accession Version NM_012414.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 4182bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-12-26
Organism Homo sapiens(human)
Product rab3 GTPase-activating protein non-catalytic subunit
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA379077.1, AB020646.2, BC131573.1, AL117631.1, BX483077.1, AC103590.2 and N93244.1. This sequence is a reference standard in the RefSeqGene project. On Oct 28, 2008 this sequence version replaced NM_012414.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.26882.1, SRR1660809.233194.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
ATGGCCTGCT CCATTGTCCA GTTCTGCTAC TTCCAGGACC TCCAGGCCGC CCGGGACTTC 
CTCTTTCCTC ACCTGCGGGA GGAGATCCTC AGCGGCGCCT TGCGGAGGGA CCCCAGTAAA 
TCAACAGACT GGGAAGATGA TGGTTGGGGA GCATGGGAAG AAAATGAACC ACAAGAACCT 
GAAGAAGAAG GAAATACTTG CAAAACACAA AAAACTTCCT GGCTCCAAGA TTGTGTTTTA 
TCCTTATCTC CAACCAATGA TCTTATGGTG ATAGCTCGAG AGCAAAAAGC TGTATTTCTA 
GTGCCAAAAT GGAAATATAG TGATAAAGGA AAGGAAGAAA TGCAATTTGC TGTTGGCTGG 
AGTGGTTCCT TAAATGTCGA AGAAGGGGAA TGTGTAACCA GTGCTCTATG TATCCCACTA 
GCAAGCCAAA AGAGGAGTTC CACTGGGCGT CCTGACTGGA CCTGCATTGT GGTGGGTTTT 
ACTTCAGGTT ATGTACGCTT CTACACTGAG AATGGTGTGC TCTTGCTTGC ACAGCTTTTG 
AATGAGGACC CAGTACTTCA ACTTAAATGC AGAACCTATG AAATACCACG ACATCCCGGC 
GTGACTGAGC AGAATGAAGA GTTGAGTATC TTATATCCAG CTGCCATTGT GACTATTGAT 
GGATTTAGCC TTTTTCAATC TCTTCGTGCT TGTCGAAATC AGGTAGCAAA AGCTGCAGCA 
TCAGGCAATG AGAACATACA ACCACCACCA TTAGCTTATA AGAAATGGGG TCTACAAGAT 
ATTGACACTA TTATTGATCA TGCTAGTGTT GGTATTATGA CTCTGTCCCC CTTTGATCAA 
ATGAAGACTG CCTCCAATAT AGGTGGATTT AATGCAGCAA TTAAAAATAG TCCACCTGCC 
ATGTCTCAGT ATATCACTGT AGGGTCCAAT CCATTTACTG GCTTCTTCTA TGCTTTAGAG 
GGAAGCACAC AACCATTATT ATCCCATGTT GCACTAGCAG TTGCAAGTAA ACTCACTTCT 
GCTTTATTTA ATGCTGCCAG TGGTTGGCTT GGTTGGAAAA GTAAGCACGA AGAAGAAGCT 
GTCCAAAAGC AAAAGCCGAA GGTTGAGCCA GCTACCCCAT TAGCTGTAAG ATTTGGACTT 
CCAGATTCTA GACGCCATGG TGAAAGCATA TGTCTGTCTC CATGTAACAC ACTGGCAGCA 
GTAACAGATG ATTTCGGCAG AGTTATTTTA TTGGATGTAG CTAGAGGAAT TGCAATACGC 
ATGTGGAAAG GGTACCGCGA CGCACAAATT GGATGGATTC AAACTGTAGA GGACCTCCAT 
GAAAGAGTGC CAGAAAAGGC AGATTTTTCC CCCTTTGGAA ATTCTCAGGG TCCAAGTCGA 
GTAGCTCAAT TCCTTGTGAT CTATGCGCCA AGAAGGGGAA TTTTAGAAGT GTGGAGCACA 
CAGCAGGGAC CTAGAGTAGG AGCTTTCAAT GTGGGGAAGC ACTGCAGGCT GCTGTATCCT 
GGCTATAAAA TAATGGGTTT AAATAATGTT ACCAGTCAGA GTTGGCAGCC ACAGACTTAT 
CAGATCTGTC TGGTTGATCC AGTGTCTGGA AGTGTGAAAA CAGTGAACGT TCCCTTCCAT 
TTAGCACTGA GTGATAAGAA GAGTGAACGA GCCAAGGATA TGCACCTAGT GAAGAAACTA 
GCAGCCTTAC TGAAAACAAA ATCTCCCAAT CTTGATTTGG TTGAAACAGA AATAAAGGAA 
TTAATTCTTG ATATTAAATA CCCTGCAACC AAAAAACAAG CTTTGGAAAG CATTTTGGCA 
AGTGAACGTT TACCATTTTC TTGCCTTAGA AACATCACTC AGACTTTAAT GGACACTTTA 
AAAAGTCAAG AACTTGAGTC TGTTGATGAA GGATTGCTAC AGTTTTGTGC CAATAAACTA 
AAACTGCTGC AACTCTATGA GTCTGTCAGT CAATTAAATT CCCTTGATTT TCATTTAGAC 
ACACCATTCT CTGATAATGA CTTGGCTCTG TTACTAAGGC TTGATGAAAA AGAACTGCTT 
AAGCTCCAGG CATTACTAGA GAAATATAAG CAAGAGAACA CCAGGACAAA TGTTCGATTT 
TCTGATGATA AAGATGGTGT GTTGCCTGTA AAAACATTCT TGGAATATTT AGAATATGAA 
AAGGATGTGC TCAACATAAA GAAAATAAGT GAAGAGGAAT ATGTGGCTTT AGGTAGTTTC 
TTTTTTTGGA AGTGTTTGCA TGGAGAAAGC TCCACTGAGG ATATGTGTCA CACTTTGGAG 
TCGGCTGGTC TTAGCCCTCA GCTGTTGTTG TCTCTGCTCC TGAGTGTTTG GCTTTCAAAG 
GAAAAGGATA TTTTGGATAA ACCACAGTCA ATCTGCTGTC TTCATACCAT GCTGTCCCTC 
CTGAGCAAGA TGAAAGTGGC CATCGATGAG ACCTGGGATT CTCAGTCTGT GTCCCCATGG 
TGGCAGCAGA TGCGCACAGC CTGTATTCAG TCTGAGAACA ATGGAGCCGC TCTGTTGTCT 
GCGCATGTTG GGCATTCTGT TGCTGCACAG ATATCAAACA ACATGACAGA GAAAAAATTT 
TCCCAAACAG TTTTGGGTGC TGATTCAGAG GCCCTCACTG ATTCCTGGGA GGCACTTTCT 
CTTGACACTG AGTACTGGAA ACTCCTTCTG AAACAGCTGG AGGATTGTCT CATACTTCAG 
ACTCTGCTTC ACAGCAAAGG GAACACTCAG ACCTCCAAAG TGTCATCACT GCAGGCTGAG 
CCACTTCCAA GGCTTTCTGT TAAAAAGTTA TTAGAAGGAG GAAAAGGTGG CATTGCAGAC 
AGTGTAGCCA AGTGGATATT TAAACAGGAC TTCAGCCCTG AAGTATTAAA ACTGGCTAAT 
GAAGAAAGAG ATGCAGAAAA CCCAGATGAA CCCAAAGAAG GTGTTAACAG AAGTTTCCTT 
GAGGTATCAG AGATGGAGAT GGACTTAGGA GCCATACCAG ACTTACTGCA TTTAGCCTAT 
GAGCAGTTTC CTTGTAGCCT TGAGCTCGAT GTCTTGCATG CACATTGCTG CTGGGAGTAC 
GTTGTTCAGT GGAATAAAGA TCCAGAGGAA GCACGTTTTT TTGTTAGGTC AATAGAACAC 
TTGAAGCAAA TATTTAATGC ACATGTTCAA AATGGCATTG CACTGATGAT GTGGAATACG 
TTCTTAGTTA AAAGATTTTC TGCTGCTACA TACTTAATGG ATAAGGTTGG AAAATCACCA 
AAAGATAGGT TATGCCGAAG GGATGTGGGA ATGAGTGACA CAGCAATGAC ATCTTTCCTC 
GGCTCCTGTT TGGATCTTCT TCAGATCTTA ATGGAGGCAG ATGTTAGCAG GGATGAAATA 
CAGGTGCCTG TGCTGGATAC TGAGGATGCG TGGCTCTCCG TGGAAGGACC AATCTCCATA 
GTGGAACTGG CCCTTGAACA GAAGCACATC CACTACCCAC TGGTGGAGCA CCACTCCATC 
CTGTGCTCCA TCTTGTATGC AGTCATGAGG TTTTCTCTGA AGACCGTGAA GCCACTTTCA 
CTTTTTGACA GTAAGGGAAA AAATGCATTT TTCAAAGACC TAACTTCAAT TCAGTTATTA 
CCTAGTGGGG AAATGGATCC AAATTTTATT TCTGTACGAC AACAGTTCTT ATTGAAAGTT 
GTCAGTGCAG CTGTCCAGGC CCAACATTCA GCCACAAAGG TCAAAGATCC CACAGAAGAG 
GCCACACCCA CTCCTTTTGG GAAAGACCAA GATTGGCCAG CTCTAGCTGT GGATTTAGCC 
CATCACCTTC AAGTTAGTGA AGATGTTGTT AGAAGGCATT ATGTGGGGGA ACTATACAAC 
TATGGAGTTG ACCACTTAGG AGAAGAGGCC ATTCTACAGG TTCATGACAA AGAGGTCCTT 
GCCTCTCAGC TGCTGGTGCT CACGGGGCAA AGGCTGGCTC ATGCGCTTCT CCACACCCAG 
ACAAAAGAAG GAATGGAGCT GCTTGCCAGA CTTCCACCCA CACTGTGTAC TTGGCTGAAA 
GCAATGGACC CCCAGGACCT TCAAAACACT GAAGTGCCAA TTGCAACAAC AGCTAAACTA 
GTAAATAAAG TAATTGAGCT TTTACCAGAA AAACATGGGC AATATGGTCT AGCCTTACAC 
CTCATTGAAG CTGTGGAAGC CATATCTCTT CCTTCTTTAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_036546.2
CDS165..4346
Translation

Target ORF information:

RefSeq Version NM_012414.3
Organism Homo sapiens(human)
Definition Homo sapiens RAB3 GTPase activating non-catalytic protein subunit 2 (RAB3GAP2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_012414.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
ATGGCCTGCT CCATTGTCCA GTTCTGCTAC TTCCAGGACC TCCAGGCCGC CCGGGACTTC 
CTCTTTCCTC ACCTGCGGGA GGAGATCCTC AGCGGCGCCT TGCGGAGGGA CCCCAGTAAA 
TCAACAGACT GGGAAGATGA TGGTTGGGGA GCATGGGAAG AAAATGAACC ACAAGAACCT 
GAAGAAGAAG GAAATACTTG CAAAACACAA AAAACTTCCT GGCTCCAAGA TTGTGTTTTA 
TCCTTATCTC CAACCAATGA TCTTATGGTG ATAGCTCGAG AGCAAAAAGC TGTATTTCTA 
GTGCCAAAAT GGAAATATAG TGATAAAGGA AAGGAAGAAA TGCAATTTGC TGTTGGCTGG 
AGTGGTTCCT TAAATGTCGA AGAAGGGGAA TGTGTAACCA GTGCTCTATG TATCCCACTA 
GCAAGCCAAA AGAGGAGTTC CACTGGGCGT CCTGACTGGA CCTGCATTGT GGTGGGTTTT 
ACTTCAGGTT ATGTACGCTT CTACACTGAG AATGGTGTGC TCTTGCTTGC ACAGCTTTTG 
AATGAGGACC CAGTACTTCA ACTTAAATGC AGAACCTATG AAATACCACG ACATCCCGGC 
GTGACTGAGC AGAATGAAGA GTTGAGTATC TTATATCCAG CTGCCATTGT GACTATTGAT 
GGATTTAGCC TTTTTCAATC TCTTCGTGCT TGTCGAAATC AGGTAGCAAA AGCTGCAGCA 
TCAGGCAATG AGAACATACA ACCACCACCA TTAGCTTATA AGAAATGGGG TCTACAAGAT 
ATTGACACTA TTATTGATCA TGCTAGTGTT GGTATTATGA CTCTGTCCCC CTTTGATCAA 
ATGAAGACTG CCTCCAATAT AGGTGGATTT AATGCAGCAA TTAAAAATAG TCCACCTGCC 
ATGTCTCAGT ATATCACTGT AGGGTCCAAT CCATTTACTG GCTTCTTCTA TGCTTTAGAG 
GGAAGCACAC AACCATTATT ATCCCATGTT GCACTAGCAG TTGCAAGTAA ACTCACTTCT 
GCTTTATTTA ATGCTGCCAG TGGTTGGCTT GGTTGGAAAA GTAAGCACGA AGAAGAAGCT 
GTCCAAAAGC AAAAGCCGAA GGTTGAGCCA GCTACCCCAT TAGCTGTAAG ATTTGGACTT 
CCAGATTCTA GACGCCATGG TGAAAGCATA TGTCTGTCTC CATGTAACAC ACTGGCAGCA 
GTAACAGATG ATTTCGGCAG AGTTATTTTA TTGGATGTAG CTAGAGGAAT TGCAATACGC 
ATGTGGAAAG GGTACCGCGA CGCACAAATT GGATGGATTC AAACTGTAGA GGACCTCCAT 
GAAAGAGTGC CAGAAAAGGC AGATTTTTCC CCCTTTGGAA ATTCTCAGGG TCCAAGTCGA 
GTAGCTCAAT TCCTTGTGAT CTATGCGCCA AGAAGGGGAA TTTTAGAAGT GTGGAGCACA 
CAGCAGGGAC CTAGAGTAGG AGCTTTCAAT GTGGGGAAGC ACTGCAGGCT GCTGTATCCT 
GGCTATAAAA TAATGGGTTT AAATAATGTT ACCAGTCAGA GTTGGCAGCC ACAGACTTAT 
CAGATCTGTC TGGTTGATCC AGTGTCTGGA AGTGTGAAAA CAGTGAACGT TCCCTTCCAT 
TTAGCACTGA GTGATAAGAA GAGTGAACGA GCCAAGGATA TGCACCTAGT GAAGAAACTA 
GCAGCCTTAC TGAAAACAAA ATCTCCCAAT CTTGATTTGG TTGAAACAGA AATAAAGGAA 
TTAATTCTTG ATATTAAATA CCCTGCAACC AAAAAACAAG CTTTGGAAAG CATTTTGGCA 
AGTGAACGTT TACCATTTTC TTGCCTTAGA AACATCACTC AGACTTTAAT GGACACTTTA 
AAAAGTCAAG AACTTGAGTC TGTTGATGAA GGATTGCTAC AGTTTTGTGC CAATAAACTA 
AAACTGCTGC AACTCTATGA GTCTGTCAGT CAATTAAATT CCCTTGATTT TCATTTAGAC 
ACACCATTCT CTGATAATGA CTTGGCTCTG TTACTAAGGC TTGATGAAAA AGAACTGCTT 
AAGCTCCAGG CATTACTAGA GAAATATAAG CAAGAGAACA CCAGGACAAA TGTTCGATTT 
TCTGATGATA AAGATGGTGT GTTGCCTGTA AAAACATTCT TGGAATATTT AGAATATGAA 
AAGGATGTGC TCAACATAAA GAAAATAAGT GAAGAGGAAT ATGTGGCTTT AGGTAGTTTC 
TTTTTTTGGA AGTGTTTGCA TGGAGAAAGC TCCACTGAGG ATATGTGTCA CACTTTGGAG 
TCGGCTGGTC TTAGCCCTCA GCTGTTGTTG TCTCTGCTCC TGAGTGTTTG GCTTTCAAAG 
GAAAAGGATA TTTTGGATAA ACCACAGTCA ATCTGCTGTC TTCATACCAT GCTGTCCCTC 
CTGAGCAAGA TGAAAGTGGC CATCGATGAG ACCTGGGATT CTCAGTCTGT GTCCCCATGG 
TGGCAGCAGA TGCGCACAGC CTGTATTCAG TCTGAGAACA ATGGAGCCGC TCTGTTGTCT 
GCGCATGTTG GGCATTCTGT TGCTGCACAG ATATCAAACA ACATGACAGA GAAAAAATTT 
TCCCAAACAG TTTTGGGTGC TGATTCAGAG GCCCTCACTG ATTCCTGGGA GGCACTTTCT 
CTTGACACTG AGTACTGGAA ACTCCTTCTG AAACAGCTGG AGGATTGTCT CATACTTCAG 
ACTCTGCTTC ACAGCAAAGG GAACACTCAG ACCTCCAAAG TGTCATCACT GCAGGCTGAG 
CCACTTCCAA GGCTTTCTGT TAAAAAGTTA TTAGAAGGAG GAAAAGGTGG CATTGCAGAC 
AGTGTAGCCA AGTGGATATT TAAACAGGAC TTCAGCCCTG AAGTATTAAA ACTGGCTAAT 
GAAGAAAGAG ATGCAGAAAA CCCAGATGAA CCCAAAGAAG GTGTTAACAG AAGTTTCCTT 
GAGGTATCAG AGATGGAGAT GGACTTAGGA GCCATACCAG ACTTACTGCA TTTAGCCTAT 
GAGCAGTTTC CTTGTAGCCT TGAGCTCGAT GTCTTGCATG CACATTGCTG CTGGGAGTAC 
GTTGTTCAGT GGAATAAAGA TCCAGAGGAA GCACGTTTTT TTGTTAGGTC AATAGAACAC 
TTGAAGCAAA TATTTAATGC ACATGTTCAA AATGGCATTG CACTGATGAT GTGGAATACG 
TTCTTAGTTA AAAGATTTTC TGCTGCTACA TACTTAATGG ATAAGGTTGG AAAATCACCA 
AAAGATAGGT TATGCCGAAG GGATGTGGGA ATGAGTGACA CAGCAATGAC ATCTTTCCTC 
GGCTCCTGTT TGGATCTTCT TCAGATCTTA ATGGAGGCAG ATGTTAGCAG GGATGAAATA 
CAGGTGCCTG TGCTGGATAC TGAGGATGCG TGGCTCTCCG TGGAAGGACC AATCTCCATA 
GTGGAACTGG CCCTTGAACA GAAGCACATC CACTACCCAC TGGTGGAGCA CCACTCCATC 
CTGTGCTCCA TCTTGTATGC AGTCATGAGG TTTTCTCTGA AGACCGTGAA GCCACTTTCA 
CTTTTTGACA GTAAGGGAAA AAATGCATTT TTCAAAGACC TAACTTCAAT TCAGTTATTA 
CCTAGTGGGG AAATGGATCC AAATTTTATT TCTGTACGAC AACAGTTCTT ATTGAAAGTT 
GTCAGTGCAG CTGTCCAGGC CCAACATTCA GCCACAAAGG TCAAAGATCC CACAGAAGAG 
GCCACACCCA CTCCTTTTGG GAAAGACCAA GATTGGCCAG CTCTAGCTGT GGATTTAGCC 
CATCACCTTC AAGTTAGTGA AGATGTTGTT AGAAGGCATT ATGTGGGGGA ACTATACAAC 
TATGGAGTTG ACCACTTAGG AGAAGAGGCC ATTCTACAGG TTCATGACAA AGAGGTCCTT 
GCCTCTCAGC TGCTGGTGCT CACGGGGCAA AGGCTGGCTC ATGCGCTTCT CCACACCCAG 
ACAAAAGAAG GAATGGAGCT GCTTGCCAGA CTTCCACCCA CACTGTGTAC TTGGCTGAAA 
GCAATGGACC CCCAGGACCT TCAAAACACT GAAGTGCCAA TTGCAACAAC AGCTAAACTA 
GTAAATAAAG TAATTGAGCT TTTACCAGAA AAACATGGGC AATATGGTCT AGCCTTACAC 
CTCATTGAAG CTGTGGAAGC CATATCTCTT CCTTCTTTAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22188
Clone ID Related Accession (Same CDS sequence) NM_012414.3 , NM_012414.4
Accession Version NM_012414.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 4182bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-21
Organism Homo sapiens(human)
Product rab3 GTPase-activating protein non-catalytic subunit
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA379077.1, AB020646.2, BC131573.1, AL117631.1, BX483077.1, AC103590.2 and N93244.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_012414.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.233194.1, SRR1660807.139839.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000358951.7/ ENSP00000351832.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
ATGGCCTGCT CCATTGTCCA GTTCTGCTAC TTCCAGGACC TCCAGGCCGC CCGGGACTTC 
CTCTTTCCTC ACCTGCGGGA GGAGATCCTC AGCGGCGCCT TGCGGAGGGA CCCCAGTAAA 
TCAACAGACT GGGAAGATGA TGGTTGGGGA GCATGGGAAG AAAATGAACC ACAAGAACCT 
GAAGAAGAAG GAAATACTTG CAAAACACAA AAAACTTCCT GGCTCCAAGA TTGTGTTTTA 
TCCTTATCTC CAACCAATGA TCTTATGGTG ATAGCTCGAG AGCAAAAAGC TGTATTTCTA 
GTGCCAAAAT GGAAATATAG TGATAAAGGA AAGGAAGAAA TGCAATTTGC TGTTGGCTGG 
AGTGGTTCCT TAAATGTCGA AGAAGGGGAA TGTGTAACCA GTGCTCTATG TATCCCACTA 
GCAAGCCAAA AGAGGAGTTC CACTGGGCGT CCTGACTGGA CCTGCATTGT GGTGGGTTTT 
ACTTCAGGTT ATGTACGCTT CTACACTGAG AATGGTGTGC TCTTGCTTGC ACAGCTTTTG 
AATGAGGACC CAGTACTTCA ACTTAAATGC AGAACCTATG AAATACCACG ACATCCCGGC 
GTGACTGAGC AGAATGAAGA GTTGAGTATC TTATATCCAG CTGCCATTGT GACTATTGAT 
GGATTTAGCC TTTTTCAATC TCTTCGTGCT TGTCGAAATC AGGTAGCAAA AGCTGCAGCA 
TCAGGCAATG AGAACATACA ACCACCACCA TTAGCTTATA AGAAATGGGG TCTACAAGAT 
ATTGACACTA TTATTGATCA TGCTAGTGTT GGTATTATGA CTCTGTCCCC CTTTGATCAA 
ATGAAGACTG CCTCCAATAT AGGTGGATTT AATGCAGCAA TTAAAAATAG TCCACCTGCC 
ATGTCTCAGT ATATCACTGT AGGGTCCAAT CCATTTACTG GCTTCTTCTA TGCTTTAGAG 
GGAAGCACAC AACCATTATT ATCCCATGTT GCACTAGCAG TTGCAAGTAA ACTCACTTCT 
GCTTTATTTA ATGCTGCCAG TGGTTGGCTT GGTTGGAAAA GTAAGCACGA AGAAGAAGCT 
GTCCAAAAGC AAAAGCCGAA GGTTGAGCCA GCTACCCCAT TAGCTGTAAG ATTTGGACTT 
CCAGATTCTA GACGCCATGG TGAAAGCATA TGTCTGTCTC CATGTAACAC ACTGGCAGCA 
GTAACAGATG ATTTCGGCAG AGTTATTTTA TTGGATGTAG CTAGAGGAAT TGCAATACGC 
ATGTGGAAAG GGTACCGCGA CGCACAAATT GGATGGATTC AAACTGTAGA GGACCTCCAT 
GAAAGAGTGC CAGAAAAGGC AGATTTTTCC CCCTTTGGAA ATTCTCAGGG TCCAAGTCGA 
GTAGCTCAAT TCCTTGTGAT CTATGCGCCA AGAAGGGGAA TTTTAGAAGT GTGGAGCACA 
CAGCAGGGAC CTAGAGTAGG AGCTTTCAAT GTGGGGAAGC ACTGCAGGCT GCTGTATCCT 
GGCTATAAAA TAATGGGTTT AAATAATGTT ACCAGTCAGA GTTGGCAGCC ACAGACTTAT 
CAGATCTGTC TGGTTGATCC AGTGTCTGGA AGTGTGAAAA CAGTGAACGT TCCCTTCCAT 
TTAGCACTGA GTGATAAGAA GAGTGAACGA GCCAAGGATA TGCACCTAGT GAAGAAACTA 
GCAGCCTTAC TGAAAACAAA ATCTCCCAAT CTTGATTTGG TTGAAACAGA AATAAAGGAA 
TTAATTCTTG ATATTAAATA CCCTGCAACC AAAAAACAAG CTTTGGAAAG CATTTTGGCA 
AGTGAACGTT TACCATTTTC TTGCCTTAGA AACATCACTC AGACTTTAAT GGACACTTTA 
AAAAGTCAAG AACTTGAGTC TGTTGATGAA GGATTGCTAC AGTTTTGTGC CAATAAACTA 
AAACTGCTGC AACTCTATGA GTCTGTCAGT CAATTAAATT CCCTTGATTT TCATTTAGAC 
ACACCATTCT CTGATAATGA CTTGGCTCTG TTACTAAGGC TTGATGAAAA AGAACTGCTT 
AAGCTCCAGG CATTACTAGA GAAATATAAG CAAGAGAACA CCAGGACAAA TGTTCGATTT 
TCTGATGATA AAGATGGTGT GTTGCCTGTA AAAACATTCT TGGAATATTT AGAATATGAA 
AAGGATGTGC TCAACATAAA GAAAATAAGT GAAGAGGAAT ATGTGGCTTT AGGTAGTTTC 
TTTTTTTGGA AGTGTTTGCA TGGAGAAAGC TCCACTGAGG ATATGTGTCA CACTTTGGAG 
TCGGCTGGTC TTAGCCCTCA GCTGTTGTTG TCTCTGCTCC TGAGTGTTTG GCTTTCAAAG 
GAAAAGGATA TTTTGGATAA ACCACAGTCA ATCTGCTGTC TTCATACCAT GCTGTCCCTC 
CTGAGCAAGA TGAAAGTGGC CATCGATGAG ACCTGGGATT CTCAGTCTGT GTCCCCATGG 
TGGCAGCAGA TGCGCACAGC CTGTATTCAG TCTGAGAACA ATGGAGCCGC TCTGTTGTCT 
GCGCATGTTG GGCATTCTGT TGCTGCACAG ATATCAAACA ACATGACAGA GAAAAAATTT 
TCCCAAACAG TTTTGGGTGC TGATTCAGAG GCCCTCACTG ATTCCTGGGA GGCACTTTCT 
CTTGACACTG AGTACTGGAA ACTCCTTCTG AAACAGCTGG AGGATTGTCT CATACTTCAG 
ACTCTGCTTC ACAGCAAAGG GAACACTCAG ACCTCCAAAG TGTCATCACT GCAGGCTGAG 
CCACTTCCAA GGCTTTCTGT TAAAAAGTTA TTAGAAGGAG GAAAAGGTGG CATTGCAGAC 
AGTGTAGCCA AGTGGATATT TAAACAGGAC TTCAGCCCTG AAGTATTAAA ACTGGCTAAT 
GAAGAAAGAG ATGCAGAAAA CCCAGATGAA CCCAAAGAAG GTGTTAACAG AAGTTTCCTT 
GAGGTATCAG AGATGGAGAT GGACTTAGGA GCCATACCAG ACTTACTGCA TTTAGCCTAT 
GAGCAGTTTC CTTGTAGCCT TGAGCTCGAT GTCTTGCATG CACATTGCTG CTGGGAGTAC 
GTTGTTCAGT GGAATAAAGA TCCAGAGGAA GCACGTTTTT TTGTTAGGTC AATAGAACAC 
TTGAAGCAAA TATTTAATGC ACATGTTCAA AATGGCATTG CACTGATGAT GTGGAATACG 
TTCTTAGTTA AAAGATTTTC TGCTGCTACA TACTTAATGG ATAAGGTTGG AAAATCACCA 
AAAGATAGGT TATGCCGAAG GGATGTGGGA ATGAGTGACA CAGCAATGAC ATCTTTCCTC 
GGCTCCTGTT TGGATCTTCT TCAGATCTTA ATGGAGGCAG ATGTTAGCAG GGATGAAATA 
CAGGTGCCTG TGCTGGATAC TGAGGATGCG TGGCTCTCCG TGGAAGGACC AATCTCCATA 
GTGGAACTGG CCCTTGAACA GAAGCACATC CACTACCCAC TGGTGGAGCA CCACTCCATC 
CTGTGCTCCA TCTTGTATGC AGTCATGAGG TTTTCTCTGA AGACCGTGAA GCCACTTTCA 
CTTTTTGACA GTAAGGGAAA AAATGCATTT TTCAAAGACC TAACTTCAAT TCAGTTATTA 
CCTAGTGGGG AAATGGATCC AAATTTTATT TCTGTACGAC AACAGTTCTT ATTGAAAGTT 
GTCAGTGCAG CTGTCCAGGC CCAACATTCA GCCACAAAGG TCAAAGATCC CACAGAAGAG 
GCCACACCCA CTCCTTTTGG GAAAGACCAA GATTGGCCAG CTCTAGCTGT GGATTTAGCC 
CATCACCTTC AAGTTAGTGA AGATGTTGTT AGAAGGCATT ATGTGGGGGA ACTATACAAC 
TATGGAGTTG ACCACTTAGG AGAAGAGGCC ATTCTACAGG TTCATGACAA AGAGGTCCTT 
GCCTCTCAGC TGCTGGTGCT CACGGGGCAA AGGCTGGCTC ATGCGCTTCT CCACACCCAG 
ACAAAAGAAG GAATGGAGCT GCTTGCCAGA CTTCCACCCA CACTGTGTAC TTGGCTGAAA 
GCAATGGACC CCCAGGACCT TCAAAACACT GAAGTGCCAA TTGCAACAAC AGCTAAACTA 
GTAAATAAAG TAATTGAGCT TTTACCAGAA AAACATGGGC AATATGGTCT AGCCTTACAC 
CTCATTGAAG CTGTGGAAGC CATATCTCTT CCTTCTTTAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_036546.2
CDS117..4298
Translation

Target ORF information:

RefSeq Version NM_012414.4
Organism Homo sapiens(human)
Definition Homo sapiens RAB3 GTPase activating non-catalytic protein subunit 2 (RAB3GAP2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_012414.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
ATGGCCTGCT CCATTGTCCA GTTCTGCTAC TTCCAGGACC TCCAGGCCGC CCGGGACTTC 
CTCTTTCCTC ACCTGCGGGA GGAGATCCTC AGCGGCGCCT TGCGGAGGGA CCCCAGTAAA 
TCAACAGACT GGGAAGATGA TGGTTGGGGA GCATGGGAAG AAAATGAACC ACAAGAACCT 
GAAGAAGAAG GAAATACTTG CAAAACACAA AAAACTTCCT GGCTCCAAGA TTGTGTTTTA 
TCCTTATCTC CAACCAATGA TCTTATGGTG ATAGCTCGAG AGCAAAAAGC TGTATTTCTA 
GTGCCAAAAT GGAAATATAG TGATAAAGGA AAGGAAGAAA TGCAATTTGC TGTTGGCTGG 
AGTGGTTCCT TAAATGTCGA AGAAGGGGAA TGTGTAACCA GTGCTCTATG TATCCCACTA 
GCAAGCCAAA AGAGGAGTTC CACTGGGCGT CCTGACTGGA CCTGCATTGT GGTGGGTTTT 
ACTTCAGGTT ATGTACGCTT CTACACTGAG AATGGTGTGC TCTTGCTTGC ACAGCTTTTG 
AATGAGGACC CAGTACTTCA ACTTAAATGC AGAACCTATG AAATACCACG ACATCCCGGC 
GTGACTGAGC AGAATGAAGA GTTGAGTATC TTATATCCAG CTGCCATTGT GACTATTGAT 
GGATTTAGCC TTTTTCAATC TCTTCGTGCT TGTCGAAATC AGGTAGCAAA AGCTGCAGCA 
TCAGGCAATG AGAACATACA ACCACCACCA TTAGCTTATA AGAAATGGGG TCTACAAGAT 
ATTGACACTA TTATTGATCA TGCTAGTGTT GGTATTATGA CTCTGTCCCC CTTTGATCAA 
ATGAAGACTG CCTCCAATAT AGGTGGATTT AATGCAGCAA TTAAAAATAG TCCACCTGCC 
ATGTCTCAGT ATATCACTGT AGGGTCCAAT CCATTTACTG GCTTCTTCTA TGCTTTAGAG 
GGAAGCACAC AACCATTATT ATCCCATGTT GCACTAGCAG TTGCAAGTAA ACTCACTTCT 
GCTTTATTTA ATGCTGCCAG TGGTTGGCTT GGTTGGAAAA GTAAGCACGA AGAAGAAGCT 
GTCCAAAAGC AAAAGCCGAA GGTTGAGCCA GCTACCCCAT TAGCTGTAAG ATTTGGACTT 
CCAGATTCTA GACGCCATGG TGAAAGCATA TGTCTGTCTC CATGTAACAC ACTGGCAGCA 
GTAACAGATG ATTTCGGCAG AGTTATTTTA TTGGATGTAG CTAGAGGAAT TGCAATACGC 
ATGTGGAAAG GGTACCGCGA CGCACAAATT GGATGGATTC AAACTGTAGA GGACCTCCAT 
GAAAGAGTGC CAGAAAAGGC AGATTTTTCC CCCTTTGGAA ATTCTCAGGG TCCAAGTCGA 
GTAGCTCAAT TCCTTGTGAT CTATGCGCCA AGAAGGGGAA TTTTAGAAGT GTGGAGCACA 
CAGCAGGGAC CTAGAGTAGG AGCTTTCAAT GTGGGGAAGC ACTGCAGGCT GCTGTATCCT 
GGCTATAAAA TAATGGGTTT AAATAATGTT ACCAGTCAGA GTTGGCAGCC ACAGACTTAT 
CAGATCTGTC TGGTTGATCC AGTGTCTGGA AGTGTGAAAA CAGTGAACGT TCCCTTCCAT 
TTAGCACTGA GTGATAAGAA GAGTGAACGA GCCAAGGATA TGCACCTAGT GAAGAAACTA 
GCAGCCTTAC TGAAAACAAA ATCTCCCAAT CTTGATTTGG TTGAAACAGA AATAAAGGAA 
TTAATTCTTG ATATTAAATA CCCTGCAACC AAAAAACAAG CTTTGGAAAG CATTTTGGCA 
AGTGAACGTT TACCATTTTC TTGCCTTAGA AACATCACTC AGACTTTAAT GGACACTTTA 
AAAAGTCAAG AACTTGAGTC TGTTGATGAA GGATTGCTAC AGTTTTGTGC CAATAAACTA 
AAACTGCTGC AACTCTATGA GTCTGTCAGT CAATTAAATT CCCTTGATTT TCATTTAGAC 
ACACCATTCT CTGATAATGA CTTGGCTCTG TTACTAAGGC TTGATGAAAA AGAACTGCTT 
AAGCTCCAGG CATTACTAGA GAAATATAAG CAAGAGAACA CCAGGACAAA TGTTCGATTT 
TCTGATGATA AAGATGGTGT GTTGCCTGTA AAAACATTCT TGGAATATTT AGAATATGAA 
AAGGATGTGC TCAACATAAA GAAAATAAGT GAAGAGGAAT ATGTGGCTTT AGGTAGTTTC 
TTTTTTTGGA AGTGTTTGCA TGGAGAAAGC TCCACTGAGG ATATGTGTCA CACTTTGGAG 
TCGGCTGGTC TTAGCCCTCA GCTGTTGTTG TCTCTGCTCC TGAGTGTTTG GCTTTCAAAG 
GAAAAGGATA TTTTGGATAA ACCACAGTCA ATCTGCTGTC TTCATACCAT GCTGTCCCTC 
CTGAGCAAGA TGAAAGTGGC CATCGATGAG ACCTGGGATT CTCAGTCTGT GTCCCCATGG 
TGGCAGCAGA TGCGCACAGC CTGTATTCAG TCTGAGAACA ATGGAGCCGC TCTGTTGTCT 
GCGCATGTTG GGCATTCTGT TGCTGCACAG ATATCAAACA ACATGACAGA GAAAAAATTT 
TCCCAAACAG TTTTGGGTGC TGATTCAGAG GCCCTCACTG ATTCCTGGGA GGCACTTTCT 
CTTGACACTG AGTACTGGAA ACTCCTTCTG AAACAGCTGG AGGATTGTCT CATACTTCAG 
ACTCTGCTTC ACAGCAAAGG GAACACTCAG ACCTCCAAAG TGTCATCACT GCAGGCTGAG 
CCACTTCCAA GGCTTTCTGT TAAAAAGTTA TTAGAAGGAG GAAAAGGTGG CATTGCAGAC 
AGTGTAGCCA AGTGGATATT TAAACAGGAC TTCAGCCCTG AAGTATTAAA ACTGGCTAAT 
GAAGAAAGAG ATGCAGAAAA CCCAGATGAA CCCAAAGAAG GTGTTAACAG AAGTTTCCTT 
GAGGTATCAG AGATGGAGAT GGACTTAGGA GCCATACCAG ACTTACTGCA TTTAGCCTAT 
GAGCAGTTTC CTTGTAGCCT TGAGCTCGAT GTCTTGCATG CACATTGCTG CTGGGAGTAC 
GTTGTTCAGT GGAATAAAGA TCCAGAGGAA GCACGTTTTT TTGTTAGGTC AATAGAACAC 
TTGAAGCAAA TATTTAATGC ACATGTTCAA AATGGCATTG CACTGATGAT GTGGAATACG 
TTCTTAGTTA AAAGATTTTC TGCTGCTACA TACTTAATGG ATAAGGTTGG AAAATCACCA 
AAAGATAGGT TATGCCGAAG GGATGTGGGA ATGAGTGACA CAGCAATGAC ATCTTTCCTC 
GGCTCCTGTT TGGATCTTCT TCAGATCTTA ATGGAGGCAG ATGTTAGCAG GGATGAAATA 
CAGGTGCCTG TGCTGGATAC TGAGGATGCG TGGCTCTCCG TGGAAGGACC AATCTCCATA 
GTGGAACTGG CCCTTGAACA GAAGCACATC CACTACCCAC TGGTGGAGCA CCACTCCATC 
CTGTGCTCCA TCTTGTATGC AGTCATGAGG TTTTCTCTGA AGACCGTGAA GCCACTTTCA 
CTTTTTGACA GTAAGGGAAA AAATGCATTT TTCAAAGACC TAACTTCAAT TCAGTTATTA 
CCTAGTGGGG AAATGGATCC AAATTTTATT TCTGTACGAC AACAGTTCTT ATTGAAAGTT 
GTCAGTGCAG CTGTCCAGGC CCAACATTCA GCCACAAAGG TCAAAGATCC CACAGAAGAG 
GCCACACCCA CTCCTTTTGG GAAAGACCAA GATTGGCCAG CTCTAGCTGT GGATTTAGCC 
CATCACCTTC AAGTTAGTGA AGATGTTGTT AGAAGGCATT ATGTGGGGGA ACTATACAAC 
TATGGAGTTG ACCACTTAGG AGAAGAGGCC ATTCTACAGG TTCATGACAA AGAGGTCCTT 
GCCTCTCAGC TGCTGGTGCT CACGGGGCAA AGGCTGGCTC ATGCGCTTCT CCACACCCAG 
ACAAAAGAAG GAATGGAGCT GCTTGCCAGA CTTCCACCCA CACTGTGTAC TTGGCTGAAA 
GCAATGGACC CCCAGGACCT TCAAAACACT GAAGTGCCAA TTGCAACAAC AGCTAAACTA 
GTAAATAAAG TAATTGAGCT TTTACCAGAA AAACATGGGC AATATGGTCT AGCCTTACAC 
CTCATTGAAG CTGTGGAAGC CATATCTCTT CCTTCTTTAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

The RAB GTPase RAB18 modulates macroautophagy and proteostasis.
Biochemical and biophysical research communications486(3)738-743(2017 05)
Feldmann A,Bekbulat F,Huesmann H,Ulbrich S,Tatzelt J,Behl C,Kern A


book

FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.
PloS one12(6)e0178518(2017)
Rasnitsyn A,Doucette L,Seifi M,Footz T,Raymond V,Walter MA


book

RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy.
Autophagy10(12)2297-309(2014)
Spang N,Feldmann A,Huesmann H,Bekbulat F,Schmitt V,Hiebel C,Koziollek-Drechsler I,Clement AM,Moosmann B,Jung J,Behrends C,Dikic I,Kern A,Behl C