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HLA-DPB1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol HLA-DPB1
Entrez Gene ID 3115
Full Name major histocompatibility complex, class II, DP beta 1
Synonyms DPB1, HLA-DP, HLA-DP1B, HLA-DPB
General protein information
Preferred Names
HLA class II histocompatibility antigen, DP beta 1 chain
Names
HLA class II histocompatibility antigen, DP beta 1 chain
MHC HLA DPB1
HLA DP14-beta chain
MHC class II HLA-DRB1
class II HLA beta chain
MHC class II antigen DPB1
MHC class II HLA-DP-beta-1
MHC class II antigen DPbeta1
MHC class II antigen beta chain
beta1 domain MHC class II HLA DPB
MHC class II antigen DP beta 1 chain
HLA-DP histocompatibility type, beta-1 subunit
HLA class II histocompatibility antigen, DP(W4) beta chain
major histocompatibility complex class II antigen beta chain
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p21.3

Summary HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

142858

Disorder Html: {Beryllium disease, chronic, susceptibility to} (3)

mRNA and Protein(s)

mRNA Protein Name
NM_002121 NP_002112 HLA class II histocompatibility antigen, DP beta 1 chain precursor
XM_006715078 XP_006715141 HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
XM_006725040 XP_006725103 HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
XM_006725699 XP_006725762 HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
XM_006725817 XP_006725880 HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
XM_006725908 XP_006725971 HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
XM_006725998 XP_006726061 HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
XM_006726088 XP_006726151 HLA class II histocompatibility antigen, DP beta 1 chain isoform X1



Homo sapiens (human) HLA-DPB1 NP_002112.3
Pan troglodytes (chimpanzee) PATR-DPB1 XP_518391.3
Macaca mulatta (Rhesus monkey) MAMU-DPB NP_001127765.1
Gallus gallus (chicken) BLB3 XP_423039.4
Gallus gallus (chicken) BLB2 XP_004945723.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following HLA-DPB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HLA-DPB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu20874
NM_002121 Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu40287 XM_006715078 PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OHu54617 XM_006725040 PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu40287 XM_006725699 PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OHu40287 XM_006725817 PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OHu54617 XM_006725908 PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu40287 XM_006725998 PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OHu40287 XM_006726088 PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu20874
Clone ID Related Accession (Same CDS sequence) NM_002121
Accession Version NM_002121.5 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 777bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DP beta 1 chain precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP213121.1, AL645931.7 and M28202.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2011 this sequence version replaced gi:24797075. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M83664.1, BC013184.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGATGGTTC TGCAGGTTTC TGCGGCCCCC CGGACAGTGG CTCTGACGGC GTTACTGATG 
GTGCTGCTCA CATCTGTGGT CCAGGGCAGG GCCACTCCAG AGAATTACCT TTTCCAGGGA
CGGCAGGAAT GCTACGCGTT TAATGGGACA CAGCGCTTCC TGGAGAGATA CATCTACAAC
CGGGAGGAGT TCGCGCGCTT CGACAGCGAC GTGGGGGAGT TCCGGGCGGT GACGGAGCTG
GGGCGGCCTG CTGCGGAGTA CTGGAACAGC CAGAAGGACA TCCTGGAGGA GAAGCGGGCA
GTGCCGGACA GGATGTGCAG ACACAACTAC GAGCTGGGCG GGCCCATGAC CCTGCAGCGC
CGAGTCCAGC CTAGGGTGAA TGTTTCCCCC TCCAAGAAGG GGCCCTTGCA GCACCACAAC
CTGCTTGTCT GCCACGTGAC GGATTTCTAC CCAGGCAGCA TTCAAGTCCG ATGGTTCCTG
AATGGACAGG AGGAAACAGC TGGGGTCGTG TCCACCAACC TGATCCGTAA TGGAGACTGG
ACCTTCCAGA TCCTGGTGAT GCTGGAAATG ACCCCCCAGC AGGGAGATGT CTACACCTGC
CAAGTGGAGC ACACCAGCCT GGATAGTCCT GTCACCGTGG AGTGGAAGGC ACAGTCTGAT
TCTGCCCGGA GTAAGACATT GACGGGAGCT GGGGGCTTCG TGCTGGGGCT CATCATCTGT
GGAGTGGGCA TCTTCATGCA CAGGAGGAGC AAGAAAGTTC AACGAGGATC TGCATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002112.3
CDS117..893
Misc Feature(1)57..59(+)
Misc Feature(2)204..479(+)
Misc Feature(3)243..455(+)
Misc Feature(4)480..761(+)
Misc Feature(5)486..767(+)
Misc Feature(6)501..665(+)
Misc Feature(7)540..758(+)
Misc Feature(8)564..662(+)
Misc Feature(9)762..791(+)
Misc Feature(10)792..854(+)
Exon (1)1..216
Gene:HLA-DPB1
Gene Synonym:
Exon (2)217..480
Gene:HLA-DPB1
Gene Synonym:
Exon (3)481..762
Gene:HLA-DPB1
Gene Synonym:
Exon (4)763..873
Gene:HLA-DPB1
Gene Synonym:
Exon (5)874..897
Gene:HLA-DPB1
Gene Synonym:
Exon (6)898..4055
Gene:HLA-DPB1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002121
Organism Homo sapiens (human)
Definition Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002121

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGATGGTTC TGCAGGTTTC TGCGGCCCCC CGGACAGTGG CTCTGACGGC GTTACTGATG 
GTGCTGCTCA CATCTGTGGT CCAGGGCAGG GCCACTCCAG AGAATTACCT TTTCCAGGGA
CGGCAGGAAT GCTACGCGTT TAATGGGACA CAGCGCTTCC TGGAGAGATA CATCTACAAC
CGGGAGGAGT TCGCGCGCTT CGACAGCGAC GTGGGGGAGT TCCGGGCGGT GACGGAGCTG
GGGCGGCCTG CTGCGGAGTA CTGGAACAGC CAGAAGGACA TCCTGGAGGA GAAGCGGGCA
GTGCCGGACA GGATGTGCAG ACACAACTAC GAGCTGGGCG GGCCCATGAC CCTGCAGCGC
CGAGTCCAGC CTAGGGTGAA TGTTTCCCCC TCCAAGAAGG GGCCCTTGCA GCACCACAAC
CTGCTTGTCT GCCACGTGAC GGATTTCTAC CCAGGCAGCA TTCAAGTCCG ATGGTTCCTG
AATGGACAGG AGGAAACAGC TGGGGTCGTG TCCACCAACC TGATCCGTAA TGGAGACTGG
ACCTTCCAGA TCCTGGTGAT GCTGGAAATG ACCCCCCAGC AGGGAGATGT CTACACCTGC
CAAGTGGAGC ACACCAGCCT GGATAGTCCT GTCACCGTGG AGTGGAAGGC ACAGTCTGAT
TCTGCCCGGA GTAAGACATT GACGGGAGCT GGGGGCTTCG TGCTGGGGCT CATCATCTGT
GGAGTGGGCA TCTTCATGCA CAGGAGGAGC AAGAAAGTTC AACGAGGATC TGCATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu40287
Clone ID Related Accession (Same CDS sequence) XM_006715078 , XM_006725699 , XM_006725817 , XM_006725998 , XM_006726088
Accession Version XM_006715078.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 465bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_007592.16) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578811641. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCCTGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006715141.1
CDS361..825
Misc Feature(1)418..699(+)
Misc Feature(2)433..597(+)
Misc Feature(3)472..690(+)
Misc Feature(4)496..594(+)
Translation

Target ORF information:

RefSeq Version XM_006715078
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006715078

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCCTGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu54617
Clone ID Related Accession (Same CDS sequence) XM_006725040 , XM_006725908
Accession Version XM_006725040.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 465bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167244.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578839599. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCATGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006725103.1
CDS321..785
Misc Feature(1)378..659(+)
Misc Feature(2)393..557(+)
Misc Feature(3)432..650(+)
Misc Feature(4)456..554(+)
Translation

Target ORF information:

RefSeq Version XM_006725040
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006725040

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCATGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu40287
Clone ID Related Accession (Same CDS sequence) XM_006715078 , XM_006725699 , XM_006725817 , XM_006725998 , XM_006726088
Accession Version XM_006725699.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 465bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167245.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578841357. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCCTGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006725762.1
CDS361..825
Misc Feature(1)418..699(+)
Misc Feature(2)433..597(+)
Misc Feature(3)472..690(+)
Misc Feature(4)496..594(+)
Translation

Target ORF information:

RefSeq Version XM_006725699
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006725699

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCCTGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu40287
Clone ID Related Accession (Same CDS sequence) XM_006715078 , XM_006725699 , XM_006725817 , XM_006725998 , XM_006726088
Accession Version XM_006725817.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 465bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167246.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578841634. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCCTGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006725880.1
CDS318..782
Misc Feature(1)375..656(+)
Misc Feature(2)390..554(+)
Misc Feature(3)429..647(+)
Misc Feature(4)453..551(+)
Translation

Target ORF information:

RefSeq Version XM_006725817
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006725817

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCCTGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu54617
Clone ID Related Accession (Same CDS sequence) XM_006725040 , XM_006725908
Accession Version XM_006725908.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 465bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167247.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578841859. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCATGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006725971.1
CDS321..785
Misc Feature(1)378..659(+)
Misc Feature(2)393..557(+)
Misc Feature(3)432..650(+)
Misc Feature(4)456..554(+)
Translation

Target ORF information:

RefSeq Version XM_006725908
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006725908

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCATGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu40287
Clone ID Related Accession (Same CDS sequence) XM_006715078 , XM_006725699 , XM_006725817 , XM_006725998 , XM_006726088
Accession Version XM_006725998.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 465bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167248.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578842075. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCCTGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006726061.1
CDS319..783
Misc Feature(1)376..657(+)
Misc Feature(2)391..555(+)
Misc Feature(3)430..648(+)
Misc Feature(4)454..552(+)
Translation

Target ORF information:

RefSeq Version XM_006725998
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006725998

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCCTGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu40287
Clone ID Related Accession (Same CDS sequence) XM_006715078 , XM_006725699 , XM_006725817 , XM_006725998 , XM_006726088
Accession Version XM_006726088.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 465bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DP beta 1 chain isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167249.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578842308. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCCTGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006726151.1
CDS361..825
Misc Feature(1)418..699(+)
Misc Feature(2)433..597(+)
Misc Feature(3)472..690(+)
Misc Feature(4)496..594(+)
Translation

Target ORF information:

RefSeq Version XM_006726088
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006726088

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGTGCAGAC ACAACTACGA GCTGGGCGGG CCCATGACCC TGCAGCGCCG AGTCCAGCCT 
AGGGTGAATG TTTCCCCCTC CAAGAAGGGG CCCTTGCAGC ACCACAACCT GCTTGTCTGC
CACGTGACGG ATTTCTACCC AGGCAGCATT CAAGTCCGAT GGTTCCTGAA TGGACAGGAG
GAAACAGCTG GGGTCGTGTC CACCAACCTG ATCCGTAATG GAGACTGGAC CTTCCAGATC
CTGGTGATGC TGGAAATGAC CCCCCAGCAG GGAGATGTCT ACACCTGCCA AGTGGAGCAC
ACCAGCCTGG ATAGTCCTGT CACCGTGGAG TGGAAGGCAC AGTCTGATTC TGCCCGGAGT
AAGACATTGA CGGGAGCTGG GGGCTTCGTG CTGGGGCTCA TCATCTGTGG AGTGGGCATC
TTCATGCACA GGAGGAGCAA GAAAGTTCAA CGAGGATCTG CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

A novel family of human leukocyte antigen class II receptors may have its origin in archaic human species
J. Biol. Chem. 289 (2), 639-653 (2014)
Temme S, Zacharias M, Neumann J, Wohlfromm S, Konig A, Temme N, Springer S, Trowsdale J and Koch N.


book

HLA-DPB1*04:01 allele is associated with non-obstructive azoospermia in Japanese patients
Hum. Genet. 132 (12), 1405-1411 (2013)
Jinam TA, Nakaoka H, Hosomichi K, Mitsunaga S, Okada H, Tanaka A, Tanaka K and Inoue I.


book

A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjogren's syndrome at 7q11.23
Nat. Genet. 45 (11), 1361-1365 (2013)
Li Y, Zhang K, Chen H, Sun F, Xu J, Wu Z, Li P, Zhang L, Du Y, Luan H, Li X, Wu L, Li H, Wu H, Li X, Li X, Zhang X, Gong L, Dai L, Sun L, Zuo X, Xu J, Gong H, Li Z, Tong S, Wu M, Li X, Xiao W, Wang G, Zhu P, Shen M, Liu S, Zhao D, Liu W, Wang Y, Huang C, Jiang Q, Liu G, Liu B, Hu S, Zhang W, Zhang Z, You X, Li M, Hao W, Zhao C, Leng X, Bi L, Wang Y, Zhang F, Shi Q, Qi W, Zhang X, Jia Y, Su J, Li Q, Hou Y, Wu Q, Xu D, Zheng W, Zhang M, Wang Q, Fei Y, Zhang X, Li J, Jiang Y, Tian X, Zhao L, Wang L, Zhou B, Li Y, Zhao Y, Zeng X, Ott J, Wang J and Zhang F.


book

A genome-wide association study identified new variants associated with the risk of chronic hepatitis B
Hum. Mol. Genet. 22 (20), 4233-4238 (2013)
Kim,Y.J., Kim,H.Y., Lee,J.H., Yu,S.J., Yoon,J.H., Lee,H.S., Kim,C.Y., Cheong,J.Y., Cho,S.W., Park,N.H., Park,B.L., Namgoong,S., Kim,L.H., Cheong,H.S. and Shin,H.D.


book

Correlation between human leukocyte antigen class II alleles and HAI titers detected post-influenza vaccination
PLoS ONE 8 (8), E71376 (2013)
Moss AJ, Gaughran FP, Karasu A, Gilbert AS, Mann AJ, Gelder CM, Oxford JS, Stephens HA and Lambkin-Williams R.


book

HLA class II nucleotide sequences, 1992
Tissue Antigens 40 (5), 229-243 (1992)
Marsh SG and Bodmer JG.


book

A novel HLA-DPB1 sequence, DPB1*2301
Tissue Antigens 40 (2), 108-110 (1992)
Eiermann TH, Uhl S, Fakler J and Goldmann SF.


book

Family study on HLA-DPB1 polymorphism: linkage analysis with HLA-DR/DQ and two 'new' alleles
Hum. Immunol. 34 (3), 203-211 (1992)
Mitsunaga S, Kuwata S, Tokunaga K, Uchikawa C, Takahashi K, Akaza T, Mitomi Y and Juji T.


book

A new HLA-DPB1 allele from a patient with systemic lupus erythematosus
Tissue Antigens 39 (4), 216-219 (1992)
Korioth F, Hartung K, Deicher H and Frey J.


book

Positive correlation between oligonucleotide typing and T-cell recognition of HLA-DP molecules
Immunogenetics 34 (1), 12-22 (1991)
de Koster HS, Kenter MJ, D'Amaro J, Luiten RM, Schroeijers WE, Giphart MJ and Termijtelen A.


 
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