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LTBR cDNA ORF clone, Homo sapiens(Human)

Gene Symbol LTBR
Entrez Gene ID 4055
Full Name lymphotoxin beta receptor
Synonyms CD18,D12S370,LT-BETA-R,TNF-R-III,TNFCR,TNFR-RP,TNFR2-RP,TNFR3,TNFRSF3
General protein information
Preferred Names

lymphotoxin beta receptor

Names

tumor necrosis factor receptor superfamily member 3
lymphotoxin B receptor
lymphotoxin beta receptor (TNFR superfamily, member 3)
tumor necrosis factor C receptor
tumor necrosis factor receptor 2-related protein
tumor necrosis factor receptor type III

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

12

12p13.31

Disorder MIM:

600979


mRNA and Protein(s)

mRNA Protein Name
NM_002342.2 NP_002333.1 tumor necrosis factor receptor superfamily member 3 isoform 1 precursor
XM_005253688.1 XP_005253745.1 tumor necrosis factor receptor superfamily member 3 isoform X1
XM_006718983.2 XP_006719046.1 tumor necrosis factor receptor superfamily member 3 isoform X2
NM_001270987.1 NP_001257916.1 tumor necrosis factor receptor superfamily member 3 isoform 2



Canis lupus familiaris (dog) LTBR XP_543855.3
Mus musculus (house mouse) Ltbr NP_034866.1
Rattus norvegicus (Norway rat) Ltbr NP_001008316.1
Homo sapiens (human) LTBR NP_002333.1
Macaca mulatta (rhesus monkey) LTBR XP_001103746.1
Pan troglodytes (chimpanzee) LTBR XP_508950.2
Bos taurus (cattle) LTBR NP_001096698.1


Related articles in PubMed

Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade.
Tang H, Wang Y, Chlewicki LK, Zhang Y, Guo J, Liang W, Wang J, Wang X, Fu YX
Cancer cell29(3)285-96(2016 Mar)

Activation of lymphotoxin-beta receptor enhances the LPS-induced expression of IL-8 through NF-κB and IRF-1.
Jang SW, Lim SG, Suk K, Lee WH
Immunology letters165(2)63-9(2015 Jun)

Herpesvirus entry mediator (HVEM) attenuates signals mediated by the lymphotoxin β receptor (LTβR) in human cells stimulated by the shared ligand LIGHT.
Bechill J, Muller WJ
Molecular immunology62(1)96-103(2014 Nov)

Lymphotoxin β receptor signaling induces IL-8 production in human bronchial epithelial cells.
Mikami Y, Matsuzaki H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y
PloS one9(12)e114791(2014)

Biology and signal transduction pathways of the Lymphotoxin-αβ/LTβR system.
Remouchamps C, Boutaffala L, Ganeff C, Dejardin E
Cytokine & growth factor reviews22(5-6)301-10(2011 Oct-Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

membrane-bound lymphotoxin-beta receptor (LTbetaR) and CXC chemokine receptor 2 (CXCR2), is involved in type B EAE development
Title: An interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damage.

LIGHT and LTBR interaction increases the survival and proliferation of human bone marrow-derived mesenchymal stem cells, and therefore, LIGHT might play an important role in stem cell therapy.
Title: LIGHT (TNFSF14) Increases the Survival and Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells.

We found that LTbetaR polymorphisms caused severe BPH. Thus, LTbetaR may contribute to the risk of BPH development.
Title: Association of LTβR gene polymorphisms with prostate volume in benign prostatic hyperplasia in the Korean population.

activation enhances the LPS-induced expression of IL-8 through NF-kappaB and IRF-1
Title: Activation of lymphotoxin-beta receptor enhances the LPS-induced expression of IL-8 through NF-κB and IRF-1.

LIGHT, via LTbetaR signaling, may contribute to exacerbation of airway neutrophilic inflammation through cytokine and chemokine production by bronchial epithelial cells.
Title: Lymphotoxin β receptor signaling induces IL-8 production in human bronchial epithelial cells.

The following LTBR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LTBR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu16923 NM_002342.2
Latest version!
Homo sapiens lymphotoxin beta receptor (LTBR), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu19887 NM_001270987.1
Latest version!
Homo sapiens lymphotoxin beta receptor (LTBR), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu45969 XM_005253688.1
Latest version!
Homo sapiens lymphotoxin beta receptor (LTBR), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu45970 XM_006718983.2
Latest version!
Homo sapiens lymphotoxin beta receptor (LTBR), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu16923
Clone ID Related Accession (Same CDS sequence) NM_002342.2
Accession Version NM_002342.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1308bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-10-06
Organism Homo sapiens(Human)
Product tumor necrosis factor receptor superfamily member 3 isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA679291.1, L04270.1, BC026262.1 and AK027080.1. On Aug 29, 2012 this sequence version replaced NM_002342.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK027080.1, BC026262.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCTCCTGC CTTGGGCCAC CTCTGCCCCC GGCCTGGCCT GGGGGCCTCT GGTGCTGGGC 
CTCTTCGGGC TCCTGGCAGC ATCGCAGCCC CAGGCGGTGC CTCCATATGC GTCGGAGAAC
CAGACCTGCA GGGACCAGGA AAAGGAATAC TATGAGCCCC AGCACCGCAT CTGCTGCTCC
CGCTGCCCGC CAGGCACCTA TGTCTCAGCT AAATGTAGCC GCATCCGGGA CACAGTTTGT
GCCACATGTG CCGAGAATTC CTACAACGAG CACTGGAACT ACCTGACCAT CTGCCAGCTG
TGCCGCCCCT GTGACCCAGT GATGGGCCTC GAGGAGATTG CCCCCTGCAC AAGCAAACGG
AAGACCCAGT GCCGCTGCCA GCCGGGAATG TTCTGTGCTG CCTGGGCCCT CGAGTGTACA
CACTGCGAGC TACTTTCTGA CTGCCCGCCT GGCACTGAAG CCGAGCTCAA AGATGAAGTT
GGGAAGGGTA ACAACCACTG CGTCCCCTGC AAGGCCGGGC ACTTCCAGAA TACCTCCTCC
CCCAGCGCCC GCTGCCAGCC CCACACCAGG TGTGAGAACC AAGGTCTGGT GGAGGCAGCT
CCAGGCACTG CCCAGTCCGA CACAACCTGC AAAAATCCAT TAGAGCCACT GCCCCCAGAG
ATGTCAGGAA CCATGCTGAT GCTGGCCGTT CTGCTGCCAC TGGCCTTCTT TCTGCTCCTT
GCCACCGTCT TCTCCTGCAT CTGGAAGAGC CACCCTTCTC TCTGCAGGAA ACTGGGATCG
CTGCTCAAGA GGCGTCCGCA GGGAGAGGGA CCCAATCCTG TAGCTGGAAG CTGGGAGCCT
CCGAAGGCCC ATCCATACTT CCCTGACTTG GTACAGCCAC TGCTACCCAT TTCTGGAGAT
GTTTCCCCAG TATCCACTGG GCTCCCCGCA GCCCCAGTTT TGGAGGCAGG GGTGCCGCAA
CAGCAGAGTC CTCTGGACCT GACCAGGGAG CCGCAGTTGG AACCCGGGGA GCAGAGCCAG
GTGGCCCACG GTACCAATGG CATTCATGTC ACCGGCGGGT CTATGACTAT CACTGGCAAC
ATCTACATCT ACAATGGACC AGTACTGGGG GGACCACCGG GTCCTGGAGA CCTCCCAGCT
ACCCCCGAAC CTCCATACCC CATTCCCGAA GAGGGGGACC CTGGCCCTCC CGGGCTCTCT
ACACCCCACC AGGAAGATGG CAAGGCTTGG CACCTAGCGG AGACAGAGCA CTGTGGTGCC
ACACCCTCTA ACAGGGGCCC AAGGAACCAA TTTATCACCC ATGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002333.1
CDS327..1634
Misc Feature(1)210..212
Misc Feature(2)357..830
Misc Feature(3)390..566
Misc Feature(4)573..698
Misc Feature(5)702..827
Misc Feature(6)768..>956
Misc Feature(7)834..956
Exon (1)1..422
Exon (2)423..519
Exon (3)520..645
Exon (4)646..798
Exon (5)799..895
Exon (6)896..993
Exon (7)994..1101
Exon (8)1102..1127
Exon (9)1128..1356
Exon (10)1357..2268
Translation

Target ORF information:

RefSeq Version NM_002342.2
Organism Homo sapiens(Human)
Definition Homo sapiens lymphotoxin beta receptor (LTBR), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002342.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCTCCTGC CTTGGGCCAC CTCTGCCCCC GGCCTGGCCT GGGGGCCTCT GGTGCTGGGC 
CTCTTCGGGC TCCTGGCAGC ATCGCAGCCC CAGGCGGTGC CTCCATATGC GTCGGAGAAC
CAGACCTGCA GGGACCAGGA AAAGGAATAC TATGAGCCCC AGCACCGCAT CTGCTGCTCC
CGCTGCCCGC CAGGCACCTA TGTCTCAGCT AAATGTAGCC GCATCCGGGA CACAGTTTGT
GCCACATGTG CCGAGAATTC CTACAACGAG CACTGGAACT ACCTGACCAT CTGCCAGCTG
TGCCGCCCCT GTGACCCAGT GATGGGCCTC GAGGAGATTG CCCCCTGCAC AAGCAAACGG
AAGACCCAGT GCCGCTGCCA GCCGGGAATG TTCTGTGCTG CCTGGGCCCT CGAGTGTACA
CACTGCGAGC TACTTTCTGA CTGCCCGCCT GGCACTGAAG CCGAGCTCAA AGATGAAGTT
GGGAAGGGTA ACAACCACTG CGTCCCCTGC AAGGCCGGGC ACTTCCAGAA TACCTCCTCC
CCCAGCGCCC GCTGCCAGCC CCACACCAGG TGTGAGAACC AAGGTCTGGT GGAGGCAGCT
CCAGGCACTG CCCAGTCCGA CACAACCTGC AAAAATCCAT TAGAGCCACT GCCCCCAGAG
ATGTCAGGAA CCATGCTGAT GCTGGCCGTT CTGCTGCCAC TGGCCTTCTT TCTGCTCCTT
GCCACCGTCT TCTCCTGCAT CTGGAAGAGC CACCCTTCTC TCTGCAGGAA ACTGGGATCG
CTGCTCAAGA GGCGTCCGCA GGGAGAGGGA CCCAATCCTG TAGCTGGAAG CTGGGAGCCT
CCGAAGGCCC ATCCATACTT CCCTGACTTG GTACAGCCAC TGCTACCCAT TTCTGGAGAT
GTTTCCCCAG TATCCACTGG GCTCCCCGCA GCCCCAGTTT TGGAGGCAGG GGTGCCGCAA
CAGCAGAGTC CTCTGGACCT GACCAGGGAG CCGCAGTTGG AACCCGGGGA GCAGAGCCAG
GTGGCCCACG GTACCAATGG CATTCATGTC ACCGGCGGGT CTATGACTAT CACTGGCAAC
ATCTACATCT ACAATGGACC AGTACTGGGG GGACCACCGG GTCCTGGAGA CCTCCCAGCT
ACCCCCGAAC CTCCATACCC CATTCCCGAA GAGGGGGACC CTGGCCCTCC CGGGCTCTCT
ACACCCCACC AGGAAGATGG CAAGGCTTGG CACCTAGCGG AGACAGAGCA CTGTGGTGCC
ACACCCTCTA ACAGGGGCCC AAGGAACCAA TTTATCACCC ATGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19887
Clone ID Related Accession (Same CDS sequence) NM_001270987.1
Accession Version NM_001270987.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1251bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-10-06
Organism Homo sapiens(Human)
Product tumor necrosis factor receptor superfamily member 3 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC424721.1, AK293187.1, BC026262.1 and AK027080.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293187.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGAAGCGA CAGGAATCTC ATTAGCATCT CAATTAAAGG TGCCTCCATA TGCGTCGGAG 
AACCAGACCT GCAGGGACCA GGAAAAGGAA TACTATGAGC CCCAGCACCG CATCTGCTGC
TCCCGCTGCC CGCCAGGCAC CTATGTCTCA GCTAAATGTA GCCGCATCCG GGACACAGTT
TGTGCCACAT GTGCCGAGAA TTCCTACAAC GAGCACTGGA ACTACCTGAC CATCTGCCAG
CTGTGCCGCC CCTGTGACCC AGTGATGGGC CTCGAGGAGA TTGCCCCCTG CACAAGCAAA
CGGAAGACCC AGTGCCGCTG CCAGCCGGGA ATGTTCTGTG CTGCCTGGGC CCTCGAGTGT
ACACACTGCG AGCTACTTTC TGACTGCCCG CCTGGCACTG AAGCCGAGCT CAAAGATGAA
GTTGGGAAGG GTAACAACCA CTGCGTCCCC TGCAAGGCCG GGCACTTCCA GAATACCTCC
TCCCCCAGCG CCCGCTGCCA GCCCCACACC AGGTGTGAGA ACCAAGGTCT GGTGGAGGCA
GCTCCAGGCA CTGCCCAGTC CGACACAACC TGCAAAAATC CATTAGAGCC ACTGCCCCCA
GAGATGTCAG GAACCATGCT GATGCTGGCC GTTCTGCTGC CACTGGCCTT CTTTCTGCTC
CTTGCCACCG TCTTCTCCTG CATCTGGAAG AGCCACCCTT CTCTCTGCAG GAAACTGGGA
TCGCTGCTCA AGAGGCGTCC GCAGGGAGAG GGACCCAATC CTGTAGCTGG AAGCTGGGAG
CCTCCGAAGG CCCATCCATA CTTCCCTGAC TTGGTACAGC CACTGCTACC CATTTCTGGA
GATGTTTCCC CAGTATCCAC TGGGCTCCCC GCAGCCCCAG TTTTGGAGGC AGGGGTGCCG
CAACAGCAGA GTCCTCTGGA CCTGACCAGG GAGCCGCAGT TGGAACCCGG GGAGCAGAGC
CAGGTGGCCC ACGGTACCAA TGGCATTCAT GTCACCGGCG GGTCTATGAC TATCACTGGC
AACATCTACA TCTACAATGG ACCAGTACTG GGGGGACCAC CGGGTCCTGG AGACCTCCCA
GCTACCCCCG AACCTCCATA CCCCATTCCC GAAGAGGGGG ACCCTGGCCC TCCCGGGCTC
TCTACACCCC ACCAGGAAGA TGGCAAGGCT TGGCACCTAG CGGAGACAGA GCACTGTGGT
GCCACACCCT CTAACAGGGG CCCAAGGAAC CAATTTATCA CCCATGACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001257916.1
CDS189..1439
Misc Feature(1)198..635
Misc Feature(2)198..371
Misc Feature(3)378..503
Misc Feature(4)507..632
Misc Feature(5)573..>761
Misc Feature(6)639..761
Exon (1)1..227
Exon (2)228..324
Exon (3)325..450
Exon (4)451..603
Exon (5)604..700
Exon (6)701..798
Exon (7)799..906
Exon (8)907..932
Exon (9)933..1161
Exon (10)1162..2073
Translation

Target ORF information:

RefSeq Version NM_001270987.1
Organism Homo sapiens(Human)
Definition Homo sapiens lymphotoxin beta receptor (LTBR), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001270987.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGAAGCGA CAGGAATCTC ATTAGCATCT CAATTAAAGG TGCCTCCATA TGCGTCGGAG 
AACCAGACCT GCAGGGACCA GGAAAAGGAA TACTATGAGC CCCAGCACCG CATCTGCTGC
TCCCGCTGCC CGCCAGGCAC CTATGTCTCA GCTAAATGTA GCCGCATCCG GGACACAGTT
TGTGCCACAT GTGCCGAGAA TTCCTACAAC GAGCACTGGA ACTACCTGAC CATCTGCCAG
CTGTGCCGCC CCTGTGACCC AGTGATGGGC CTCGAGGAGA TTGCCCCCTG CACAAGCAAA
CGGAAGACCC AGTGCCGCTG CCAGCCGGGA ATGTTCTGTG CTGCCTGGGC CCTCGAGTGT
ACACACTGCG AGCTACTTTC TGACTGCCCG CCTGGCACTG AAGCCGAGCT CAAAGATGAA
GTTGGGAAGG GTAACAACCA CTGCGTCCCC TGCAAGGCCG GGCACTTCCA GAATACCTCC
TCCCCCAGCG CCCGCTGCCA GCCCCACACC AGGTGTGAGA ACCAAGGTCT GGTGGAGGCA
GCTCCAGGCA CTGCCCAGTC CGACACAACC TGCAAAAATC CATTAGAGCC ACTGCCCCCA
GAGATGTCAG GAACCATGCT GATGCTGGCC GTTCTGCTGC CACTGGCCTT CTTTCTGCTC
CTTGCCACCG TCTTCTCCTG CATCTGGAAG AGCCACCCTT CTCTCTGCAG GAAACTGGGA
TCGCTGCTCA AGAGGCGTCC GCAGGGAGAG GGACCCAATC CTGTAGCTGG AAGCTGGGAG
CCTCCGAAGG CCCATCCATA CTTCCCTGAC TTGGTACAGC CACTGCTACC CATTTCTGGA
GATGTTTCCC CAGTATCCAC TGGGCTCCCC GCAGCCCCAG TTTTGGAGGC AGGGGTGCCG
CAACAGCAGA GTCCTCTGGA CCTGACCAGG GAGCCGCAGT TGGAACCCGG GGAGCAGAGC
CAGGTGGCCC ACGGTACCAA TGGCATTCAT GTCACCGGCG GGTCTATGAC TATCACTGGC
AACATCTACA TCTACAATGG ACCAGTACTG GGGGGACCAC CGGGTCCTGG AGACCTCCCA
GCTACCCCCG AACCTCCATA CCCCATTCCC GAAGAGGGGG ACCCTGGCCC TCCCGGGCTC
TCTACACCCC ACCAGGAAGA TGGCAAGGCT TGGCACCTAG CGGAGACAGA GCACTGTGGT
GCCACACCCT CTAACAGGGG CCCAAGGAAC CAATTTATCA CCCATGACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu45969
Clone ID Related Accession (Same CDS sequence) XM_005253688.1
Accession Version XM_005253688.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1200bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product tumor necrosis factor receptor superfamily member 3 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCTCCTGC CTTGGGCCAC CTCTGCCCCC GGCCTGGCCT GGGGGCCTCT GGTGCTGGGC 
CTCTTCGGGC TCCTGGCAGC ATCGCAGCCC CAGGCGGTGC CTCCATATGC GTCGGAGAAC
CAGACCTGCA GGGACCAGGA AAAGGAATAC TATGAGCCCC AGCACCGCAT CTGCTGCTCC
CGCTGCCCGC CAGGCACCTA TGTCTCAGCT AAATGTAGCC GCATCCGGGA CACAGTTTGT
GCCACATGTG CCGAGAATTC CTACAACGAG CACTGGAACT ACCTGACCAT CTGCCAGCTG
TGCCGCCCCT GTGACCCAGT GATGGGCCTC GAGGAGATTG CCCCCTGCAC AAGCAAACGG
AAGACCCAGT GCCGCTGCCA GCCGGGAATG TTCTGTGCTG CCTGGGCCCT CGAGTGTACA
CACTGCGAGC TACTTTCTGA CTGCCCGCCT GGCACTGAAG CCGAGCTCAA AGATGAAGTT
GGGAAGGGTA ACAACCACTG CGTCCCCTGC AAGGCCGGGC ACTTCCAGAA TACCTCCTCC
CCCAGCGCCC GCTGCCAGCC CCACACCAGG TGTGAGAACC AAGGTCTGGT GGAGGCAGCT
CCAGGCACTG CCCAGTCCGA CACAACCTGC AAAAATCCAT TAGAGCCACT GCCCCCAGAG
ATGTCAGGAT CGCTGCTCAA GAGGCGTCCG CAGGGAGAGG GACCCAATCC TGTAGCTGGA
AGCTGGGAGC CTCCGAAGGC CCATCCATAC TTCCCTGACT TGGTACAGCC ACTGCTACCC
ATTTCTGGAG ATGTTTCCCC AGTATCCACT GGGCTCCCCG CAGCCCCAGT TTTGGAGGCA
GGGGTGCCGC AACAGCAGAG TCCTCTGGAC CTGACCAGGG AGCCGCAGTT GGAACCCGGG
GAGCAGAGCC AGGTGGCCCA CGGTACCAAT GGCATTCATG TCACCGGCGG GTCTATGACT
ATCACTGGCA ACATCTACAT CTACAATGGA CCAGTACTGG GGGGACCACC GGGTCCTGGA
GACCTCCCAG CTACCCCCGA ACCTCCATAC CCCATTCCCG AAGAGGGGGA CCCTGGCCCT
CCCGGGCTCT CTACACCCCA CCAGGAAGAT GGCAAGGCTT GGCACCTAGC GGAGACAGAG
CACTGTGGTG CCACACCCTC TAACAGGGGC CCAAGGAACC AATTTATCAC CCATGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005253745.1
CDS287..1486
Misc Feature(1)317..790
Misc Feature(2)350..526
Misc Feature(3)533..658
Misc Feature(4)662..787
Misc Feature(5)728..>916
Misc Feature(6)794..916
Translation

Target ORF information:

RefSeq Version XM_005253688.1
Organism Homo sapiens(Human)
Definition Homo sapiens lymphotoxin beta receptor (LTBR), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005253688.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCTCCTGC CTTGGGCCAC CTCTGCCCCC GGCCTGGCCT GGGGGCCTCT GGTGCTGGGC 
CTCTTCGGGC TCCTGGCAGC ATCGCAGCCC CAGGCGGTGC CTCCATATGC GTCGGAGAAC
CAGACCTGCA GGGACCAGGA AAAGGAATAC TATGAGCCCC AGCACCGCAT CTGCTGCTCC
CGCTGCCCGC CAGGCACCTA TGTCTCAGCT AAATGTAGCC GCATCCGGGA CACAGTTTGT
GCCACATGTG CCGAGAATTC CTACAACGAG CACTGGAACT ACCTGACCAT CTGCCAGCTG
TGCCGCCCCT GTGACCCAGT GATGGGCCTC GAGGAGATTG CCCCCTGCAC AAGCAAACGG
AAGACCCAGT GCCGCTGCCA GCCGGGAATG TTCTGTGCTG CCTGGGCCCT CGAGTGTACA
CACTGCGAGC TACTTTCTGA CTGCCCGCCT GGCACTGAAG CCGAGCTCAA AGATGAAGTT
GGGAAGGGTA ACAACCACTG CGTCCCCTGC AAGGCCGGGC ACTTCCAGAA TACCTCCTCC
CCCAGCGCCC GCTGCCAGCC CCACACCAGG TGTGAGAACC AAGGTCTGGT GGAGGCAGCT
CCAGGCACTG CCCAGTCCGA CACAACCTGC AAAAATCCAT TAGAGCCACT GCCCCCAGAG
ATGTCAGGAT CGCTGCTCAA GAGGCGTCCG CAGGGAGAGG GACCCAATCC TGTAGCTGGA
AGCTGGGAGC CTCCGAAGGC CCATCCATAC TTCCCTGACT TGGTACAGCC ACTGCTACCC
ATTTCTGGAG ATGTTTCCCC AGTATCCACT GGGCTCCCCG CAGCCCCAGT TTTGGAGGCA
GGGGTGCCGC AACAGCAGAG TCCTCTGGAC CTGACCAGGG AGCCGCAGTT GGAACCCGGG
GAGCAGAGCC AGGTGGCCCA CGGTACCAAT GGCATTCATG TCACCGGCGG GTCTATGACT
ATCACTGGCA ACATCTACAT CTACAATGGA CCAGTACTGG GGGGACCACC GGGTCCTGGA
GACCTCCCAG CTACCCCCGA ACCTCCATAC CCCATTCCCG AAGAGGGGGA CCCTGGCCCT
CCCGGGCTCT CTACACCCCA CCAGGAAGAT GGCAAGGCTT GGCACCTAGC GGAGACAGAG
CACTGTGGTG CCACACCCTC TAACAGGGGC CCAAGGAACC AATTTATCAC CCATGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu45970
Clone ID Related Accession (Same CDS sequence) XM_006718983.2
Accession Version XM_006718983.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 768bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product tumor necrosis factor receptor superfamily member 3 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006718983.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCTCCTGC CTTGGGCCAC CTCTGCCCCC GGCCTGGCCT GGGGGCCTCT GGTGCTGGGC 
CTCTTCGGGC TCCTGGCAGC ATCGCAGCCC CAGGCGGTGC CTCCATATGC GTCGGAGAAC
CAGACCTGCA GGGACCAGGA AAAGGAATAC TATGAGCCCC AGCACCGCAT CTGCTGCTCC
CGCTGCCCGC CAGGCACCTA TGTCTCAGCT AAATGTAGCC GCATCCGGGA CACAGTTTGT
GCCACATGTG CCGAGAATTC CTACAACGAG CACTGGAACT ACCTGACCAT CTGCCAGCTG
TGCCGCCCCT GTGACCCAGT GATGGGCCTC GAGGAGATTG CCCCCTGCAC AAGCAAACGG
AAGACCCAGT GCCGCTGCCA GCCGGGAATG TTCTGTGCTG CCTGGGCCCT CGAGTGTACA
CACTGCGAGC TACTTTCTGA CTGCCCGCCT GGCACTGAAG CCGAGCTCAA AGATGAAGTT
GGGAAGGGTA ACAACCACTG CGTCCCCTGC AAGGCCGGGC ACTTCCAGAA TACCTCCTCC
CCCAGCGCCC GCTGCCAGCC CCACACCAGG TGTGAGAACC AAGGTCTGGT GGAGGCAGCT
CCAGGCACTG CCCAGTCCGA CACAACCTGC AAAAATCCAT TAGAGCCACT GCCCCCAGAG
ATGTCAGAAC CTGCCCTGAG CAAGGGGGTG GAGAACTTGC AAGCCCTGCT CTACCAGGCG
GCCACAGGCA GTTCCGAAGC AAGTTTCCCT ACTCTCTCAC CCCTGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006719046.1
CDS287..1054
Misc Feature(1)317..790
Misc Feature(2)350..526
Misc Feature(3)533..658
Misc Feature(4)662..787
Misc Feature(5)728..>916
Misc Feature(6)794..916
Translation

Target ORF information:

RefSeq Version XM_006718983.2
Organism Homo sapiens(Human)
Definition Homo sapiens lymphotoxin beta receptor (LTBR), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006718983.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCTCCTGC CTTGGGCCAC CTCTGCCCCC GGCCTGGCCT GGGGGCCTCT GGTGCTGGGC 
CTCTTCGGGC TCCTGGCAGC ATCGCAGCCC CAGGCGGTGC CTCCATATGC GTCGGAGAAC
CAGACCTGCA GGGACCAGGA AAAGGAATAC TATGAGCCCC AGCACCGCAT CTGCTGCTCC
CGCTGCCCGC CAGGCACCTA TGTCTCAGCT AAATGTAGCC GCATCCGGGA CACAGTTTGT
GCCACATGTG CCGAGAATTC CTACAACGAG CACTGGAACT ACCTGACCAT CTGCCAGCTG
TGCCGCCCCT GTGACCCAGT GATGGGCCTC GAGGAGATTG CCCCCTGCAC AAGCAAACGG
AAGACCCAGT GCCGCTGCCA GCCGGGAATG TTCTGTGCTG CCTGGGCCCT CGAGTGTACA
CACTGCGAGC TACTTTCTGA CTGCCCGCCT GGCACTGAAG CCGAGCTCAA AGATGAAGTT
GGGAAGGGTA ACAACCACTG CGTCCCCTGC AAGGCCGGGC ACTTCCAGAA TACCTCCTCC
CCCAGCGCCC GCTGCCAGCC CCACACCAGG TGTGAGAACC AAGGTCTGGT GGAGGCAGCT
CCAGGCACTG CCCAGTCCGA CACAACCTGC AAAAATCCAT TAGAGCCACT GCCCCCAGAG
ATGTCAGAAC CTGCCCTGAG CAAGGGGGTG GAGAACTTGC AAGCCCTGCT CTACCAGGCG
GCCACAGGCA GTTCCGAAGC AAGTTTCCCT ACTCTCTCAC CCCTGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

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