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POU6F1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol POU6F1
Entrez Gene ID 5463
Full Name POU class 6 homeobox 1
Synonyms BRN5, MPOU, TCFB1
General protein information
Preferred Names
POU domain, class 6, transcription factor 1
Names
POU domain, class 6, transcription factor 1
brn-5
brain-5
mPOU homeobox protein
brain-specific homeobox/POU domain protein 5
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13.13

Summary lac of sum

mRNA and Protein(s)

mRNA Protein Name
NM_002702 NP_002693 POU domain, class 6, transcription factor 1


Homo sapiens (human) POU6F1 NP_002693.3
Pan troglodytes (chimpanzee) POU6F1 XP_001148929.1
Macaca mulatta (Rhesus monkey) LOC694640 XP_001083309.1
Canis lupus familiaris (dog) POU6F1 XP_003433575.1
Bos taurus (cattle) POU6F1 XP_002687314.2
Mus musculus (house mouse) Pou6f1 NP_034257.1
Rattus norvegicus (Norway rat) Pou6f1 NP_001099216.1
Danio rerio (zebrafish) pou6f1 NP_571188.1
Xenopus (Silurana) tropicalis (western clawed frog) pou6f1 NP_001103520.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following POU6F1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POU6F1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu12619
NM_002702 Homo sapiens POU class 6 homeobox 1 (POU6F1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$154.50-$216.30
$309.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu12619
Clone ID Related Accession (Same CDS sequence) NM_002702
Accession Version NM_002702.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 906bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product POU domain, class 6, transcription factor 1
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL832881.1, BC051326.1, DA026332.1, DA084199.1, AC139768.14, BM703234.1, CK002954.1 and AW445212.1. On Feb 20, 2009 this sequence version replaced gi:57163992. Transcript Variant: This variant (1) represents the protein-coding transcript. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AL832881.1, BC051326.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146411, SAMEA962337 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCAGGGA TCAGCAGTCA GATCCTCACC AATGCTCAGG GACAGGTTAT TGGAACCCTT 
CCATGGGTAG TGAACTCAGC TAGTGTGGCG GCCCCAGCAC CAGCCCAAAG CCTGCAGGTC
CAGGCCGTGA CCCCCCAGCT GTTGTTGAAC GCCCAGGGCC AGGTGATTGC GACCCTGGCT
AGCAGCCCCC TGCCTCCACC TGTGGCTGTC CGGAAGCCAA GCACACCTGA GTCCCCTGCT
AAGAGTGAGG TGCAGCCCAT CCAGCCCACA CCAACCGTGC CCCAGCCTGC TGTGGTCATT
GCCAGCCCAG CTCCAGCCGC CAAGCCATCT GCCTCTGCTC CTATCCCAAT TACCTGCTCA
GAGACCCCCA CCGTCAGCCA GTTGGTGTCC AAGCCACATA CTCCAAGTCT GGATGAGGAT
GGGATCAACT TAGAAGAGAT CCGGGAGTTT GCCAAGAACT TTAAGATCCG GCGGCTCTCG
CTGGGCCTTA CACAGACCCA GGTGGGTCAG GCTCTGACTG CAACGGAAGG TCCAGCCTAC
AGCCAGTCAG CCATCTGCCG GTTCGAGAAG CTAGACATCA CACCCAAGAG TGCCCAGAAG
CTAAAGCCGG TGCTGGAAAA GTGGCTAAAC GAAGCTGAAC TGCGGAACCA GGAAGGCCAG
CAGAACCTGA TGGAGTTTGT GGGAGGCGAG CCCTCCAAGA AACGCAAACG CCGCACCTCC
TTCACCCCCC AGGCCATAGA GGCTCTCAAT GCCTATTTTG AGAAGAACCC ACTGCCCACA
GGCCAGGAGA TCACTGAAAT TGCTAAGGAG CTCAACTACG ACCGTGAGGT AGTGCGGGTC
TGGTTCTGCA ATCGGCGCCA GACGCTCAAG AACACCAGCA AGCTGAACGT CTTTCAGATC
CCTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002693.3
CDS483..1388
Misc Feature(1)114..116(+)
Misc Feature(2)897..1121(+)
Misc Feature(3)1185..1361(+)
Misc Feature(4)1185..1355(+)
Misc Feature(5)1191..1343(+)
Exon (1)1..398
Gene:POU6F1
Gene Synonym:
Exon (2)399..527
Gene:POU6F1
Gene Synonym:
Exon (3)528..731
Gene:POU6F1
Gene Synonym:
Exon (4)732..873
Gene:POU6F1
Gene Synonym:
Exon (5)874..1042
Gene:POU6F1
Gene Synonym:
Exon (6)1043..4699
Gene:POU6F1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002702
Organism Homo sapiens (human)
Definition Homo sapiens POU class 6 homeobox 1 (POU6F1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002702

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCAGGGA TCAGCAGTCA GATCCTCACC AATGCTCAGG GACAGGTTAT TGGAACCCTT 
CCATGGGTAG TGAACTCAGC TAGTGTGGCG GCCCCAGCAC CAGCCCAAAG CCTGCAGGTC
CAGGCCGTGA CCCCCCAGCT GTTGTTGAAC GCCCAGGGCC AGGTGATTGC GACCCTGGCT
AGCAGCCCCC TGCCTCCACC TGTGGCTGTC CGGAAGCCAA GCACACCTGA GTCCCCTGCT
AAGAGTGAGG TGCAGCCCAT CCAGCCCACA CCAACCGTGC CCCAGCCTGC TGTGGTCATT
GCCAGCCCAG CTCCAGCCGC CAAGCCATCT GCCTCTGCTC CTATCCCAAT TACCTGCTCA
GAGACCCCCA CCGTCAGCCA GTTGGTGTCC AAGCCACATA CTCCAAGTCT GGATGAGGAT
GGGATCAACT TAGAAGAGAT CCGGGAGTTT GCCAAGAACT TTAAGATCCG GCGGCTCTCG
CTGGGCCTTA CACAGACCCA GGTGGGTCAG GCTCTGACTG CAACGGAAGG TCCAGCCTAC
AGCCAGTCAG CCATCTGCCG GTTCGAGAAG CTAGACATCA CACCCAAGAG TGCCCAGAAG
CTAAAGCCGG TGCTGGAAAA GTGGCTAAAC GAAGCTGAAC TGCGGAACCA GGAAGGCCAG
CAGAACCTGA TGGAGTTTGT GGGAGGCGAG CCCTCCAAGA AACGCAAACG CCGCACCTCC
TTCACCCCCC AGGCCATAGA GGCTCTCAAT GCCTATTTTG AGAAGAACCC ACTGCCCACA
GGCCAGGAGA TCACTGAAAT TGCTAAGGAG CTCAACTACG ACCGTGAGGT AGTGCGGGTC
TGGTTCTGCA ATCGGCGCCA GACGCTCAAG AACACCAGCA AGCTGAACGT CTTTCAGATC
CCTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Transcription factor POU6F1 is important for proliferation of clear cell adenocarcinoma of the ovary and is a potential new molecular target
Int. J. Gynecol. Cancer 20 (2), 212-219 (2010)
Suzuki N, Yoshioka N, Uekawa A, Matsumura N, Tozawa A, Koike J, Konishi I, Kiguchi K and Ishizuka B.


book

POU6F1 is the transcription factor that might be involved in cell proliferation of clear cell adenocarcinoma of the ovary
Hum. Cell 22 (4), 94-100 (2009)
Yoshioka N, Suzuki N, Uekawa A, Kiguchi K and Ishizuka B.


book

Structure of human Brn-5 transcription factor in complex with CRH gene promoter
J. Struct. Biol. 167 (2), 159-165 (2009)
Pereira JH and Kim SH.


book

Crystallization and preliminary X-ray analysis of human Brn-5 transcription factor in complex with DNA
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64 (PT 3), 175-178 (2008)
Pereira JH, Ha SC and Kim SH.


book

Expression of transcription regulating genes in human preimplantation embryos
Hum. Reprod. 10 (10), 2787-2792 (1995)
Abdel-Rahman B, Fiddler M, Rappolee D and Pergament E.


book

A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues
Eur. J. Biochem. 220 (3), 753-762 (1994)
Wey E, Lyons GE and Schafer BW.


book

A novel POU domain protein which binds to the T-cell receptor beta enhancer
Mol. Cell. Biol. 13 (9), 5450-5460 (1993)
Messier H, Brickner H, Gaikwad J and Fotedar A.


book

Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues
Nucleic Acids Res. 20 (17), 4613-4620 (1992)
Takeda J, Seino S and Bell GI.


 
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