AP5S1 cDNA ORF clone, Homo sapiens(human)
Gene Symbol | AP5S1 |
Entrez Gene ID | 55317 |
Full Name | adaptor related protein complex 5 sigma 1 subunit |
Synonyms | C20orf29 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
NM_001204446.1 | NP_001191375.1 | AP-5 complex subunit sigma-1 |
NM_001204447.1 | NP_001191376.1 | AP-5 complex subunit sigma-1 |
NM_018347.2 | NP_060817.1 | AP-5 complex subunit sigma-1 |
NM_001204447.2 | NP_001191376.1 | AP-5 complex subunit sigma-1 |
NM_018347.3 | NP_060817.1 | AP-5 complex subunit sigma-1 |

Homo sapiens (human) | AP5S1 | NP_001191375.1 |
C20orf29 | XP_002798238.1 | |
Mus musculus (house mouse) | Ap5s1 | NP_081405.2 |
Canis lupus familiaris (dog) | AP5S1 | XP_851396.1 |
Rattus norvegicus (Norway rat) | Ap5s1 | NP_001128090.1 |
Xenopus tropicalis (tropical clawed frog) | ap5s1 | NP_001107332.1 |
Pan troglodytes (chimpanzee) | AP5S1 | XP_001163166.1 |
Bos taurus (cattle) | AP5S1 | NP_001029983.1 |
Danio rerio (zebrafish) | ap5s1 | XP_005156643.1 |

Related articles in PubMed
The fifth adaptor protein complex.
Hirst J, Barlow LD, Francisco GC, Sahlender DA, Seaman MN, Dacks JB, Robinson MS
PLoS biology9(10)e1001170(2011 Oct)
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia.
S?abicki M, Theis M, Krastev DB, Samsonov S, Mundwiller E, Junqueira M, Paszkowski-Rogacz M, Teyra J, Heninger AK, Poser I, Prieur F, Truchetto J, Confavreux C, Marelli C, Durr A, Camdessanche JP, Brice A, Shevchenko A, Pisabarro MT, Stevanin G, Buchholz F
PLoS biology8(6)e1000408(2010 Jun)
The DNA sequence and comparative analysis of human chromosome 20.
Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, Stavrides G, Almeida JP, Babbage AK, Bagguley CL, Bailey J, Barlow KF, Bates KN, Beard LM, Beare DM, Beasley OP, Bird CP, Blakey SE, Bridgeman AM, Brown AJ, Buck D, Burrill W, Butler AP, Carder C, Carter NP, Chapman JC, Clamp M, Clark G, Clark LN, Clark SY, Clee CM, Clegg S, Cobley VE, Collier RE, Connor R, Corby NR, Coulson A, Coville GJ, Deadman R, Dhami P, Dunn M, Ellington AG, Frankland JA, Fraser A, French L, Garner P, Grafham DV, Griffiths C, Griffiths MN, Gwilliam R, Hall RE, Hammond S, Harley JL, Heath PD, Ho S, Holden JL, Howden PJ, Huckle E, Hunt AR, Hunt SE, Jekosch K, Johnson CM, Johnson D, Kay MP, Kimberley AM, King A, Knights A, Laird GK, Lawlor S, Lehvaslaiho MH, Leversha M, Lloyd C, Lloyd DM, Lovell JD, Marsh VL, Martin SL, McConnachie LJ, McLay K, McMurray AA, Milne S, Mistry D, Moore MJ, Mullikin JC, Nickerson T, Oliver K, Parker A, Patel R, Pearce TA, Peck AI, Phillimore BJ, Prathalingam SR, Plumb RW, Ramsay H, Rice CM, Ross MT, Scott CE, Sehra HK, Shownkeen R, Sims S, Skuce CD, Smith ML, Soderlund C, Steward CA, Sulston JE, Swann M, Sycamore N, Taylor R, Tee L, Thomas DW, Thorpe A, Tracey A, Tromans AC, Vaudin M, Wall M, Wallis JM, Whitehead SL, Whittaker P, Willey DL, Williams L, Williams SA, Wilming L, Wray PW, Hubbard T, Durbin RM, Bentley DR, Beck S, Rogers J
Nature414(6866)865-71(2001 Dec 20-27)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following AP5S1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AP5S1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OHu32238![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001204446.1 , NM_001204447.1 , NM_018347.2 , NM_001204447.2 , NM_018347.3 | |
Accession Version | NM_001204446.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-24 | |
Organism | Homo sapiens(human) | |
Product | AP-5 complex subunit sigma-1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA253969.1, DA129391.1 and AK002030.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: DA129391.1, DA763550.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTCCACG CCTTCCTCAT TCACACCTTG AGGGCCCCGA ATACTGAGGA CACGGGCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001191375.1 |
CDS | 348..950 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGTCCACG CCTTCCTCAT TCACACCTTG AGGGCCCCGA ATACTGAGGA CACGGGCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu32238![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001204446.1 , NM_001204447.1 , NM_018347.2 , NM_001204447.2 , NM_018347.3 | |
Accession Version | NM_001204447.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-24 | |
Organism | Homo sapiens(human) | |
Product | AP-5 complex subunit sigma-1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA253969.1, AK093332.1, DB190907.1 and AI338486.1. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK093332.1, SRR1163657.50623.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTCCACG CCTTCCTCAT TCACACCTTG AGGGCCCCGA ATACTGAGGA CACGGGCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001191376.1 |
CDS | 196..798 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGTCCACG CCTTCCTCAT TCACACCTTG AGGGCCCCGA ATACTGAGGA CACGGGCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu32238![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001204446.1 , NM_001204447.1 , NM_018347.2 , NM_001204447.2 , NM_018347.3 | |
Accession Version | NM_018347.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | AP-5 complex subunit sigma-1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA253969.1, BC043344.1 and AK002030.1. On Mar 2, 2011 this sequence version replaced NM_018347.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK002030.1, SRR1660809.186259.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTCCACG CCTTCCTCAT TCACACCTTG AGGGCCCCGA ATACTGAGGA CACGGGCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_060817.1 |
CDS | 252..854 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGTCCACG CCTTCCTCAT TCACACCTTG AGGGCCCCGA ATACTGAGGA CACGGGCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu32238![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001204446.1 , NM_001204447.1 , NM_018347.2 , NM_001204447.2 , NM_018347.3 | |
Accession Version | NM_001204447.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | AP-5 complex subunit sigma-1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA253969.1, AK093332.1, DB190907.1, AI338486.1 and AL109804.41. On May 31, 2019 this sequence version replaced NM_001204447.1. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.52990.1, AK093332.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTCCACG CCTTCCTCAT TCACACCTTG AGGGCCCCGA ATACTGAGGA CACGGGCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001191376.1 |
CDS | 173..775 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGTCCACG CCTTCCTCAT TCACACCTTG AGGGCCCCGA ATACTGAGGA CACGGGCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu32238![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001204446.1 , NM_001204447.1 , NM_018347.2 , NM_001204447.2 , NM_018347.3 | |
Accession Version | NM_018347.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-01 | |
Organism | Homo sapiens(human) | |
Product | AP-5 complex subunit sigma-1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA253969.1, BC043344.1, AK002030.1 and AL109804.41. On Nov 24, 2018 this sequence version replaced NM_018347.2. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.400910.1, AK002030.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000615891.2/ ENSP00000481750.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGTCCACG CCTTCCTCAT TCACACCTTG AGGGCCCCGA ATACTGAGGA CACGGGCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_060817.1 |
CDS | 229..831 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGTCCACG CCTTCCTCAT TCACACCTTG AGGGCCCCGA ATACTGAGGA CACGGGCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
The fifth adaptor protein complex. |
![]() |
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia. |
![]() |
The DNA sequence and comparative analysis of human chromosome 20. |