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CASS4 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol CASS4
Entrez Gene ID 57091
Full Name Cas scaffolding protein family member 4
Synonyms C20orf32,CAS4,HEFL,HEPL
General protein information
Preferred Names

Cas scaffolding protein family member 4

Names

cas scaffolding protein family member 4
HEF-like protein
HEF1-EFS-p130Cas-like protein

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

20

20q13.31


mRNA and Protein(s)

mRNA Protein Name
NM_001164115.1 NP_001157587.1 cas scaffolding protein family member 4 isoform c
XM_006723831.3 XP_006723894.1 cas scaffolding protein family member 4 isoform X1
NM_020356.3 NP_065089.2 cas scaffolding protein family member 4 isoform a
NM_001164116.1 NP_001157588.1 cas scaffolding protein family member 4 isoform a
NM_001164114.1 NP_001157586.1 cas scaffolding protein family member 4 isoform b



Rattus norvegicus (Norway rat) Cass4 NP_001178673.1
Gallus gallus (chicken) CASS4 XP_004947286.1
Xenopus tropicalis (tropical clawed frog) cass4 XP_002942319.2
Pan troglodytes (chimpanzee) CASS4 XP_001169779.1
Canis lupus familiaris (dog) CASS4 XP_534461.4
Mus musculus (house mouse) Cass4 NP_001263351.1
Macaca mulatta (rhesus monkey) CASS4 XP_001090515.1
Homo sapiens (human) CASS4 NP_001157588.1
Bos taurus (cattle) CASS4 XP_005215014.1
Danio rerio (zebrafish) LOC100000938 XP_001341038.2


Related articles in PubMed

Overexpression of CASS4 promotes invasion in non-small cell lung cancer by activating the AKT signaling pathway and inhibiting E-cadherin expression.
Li A, Zhang W, Xia H, Miao Y, Zhou H, Zhang X, Dong Q, Li Q, Qiu X, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(11)15157-15164(2016 Nov)

Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members.
Deneka A, Korobeynikov V, Golemis EA
Gene570(1)25-35(2015 Oct)

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.
Li Q, Wojciechowski R, Simpson CL, Hysi PG, Verhoeven VJ, Ikram MK, Höhn R, Vitart V, Hewitt AW, Oexle K, Mäkelä KM, MacGregor S, Pirastu M, Fan Q, Cheng CY, St Pourcain B, McMahon G, Kemp JP, Northstone K, Rahi JS, Cumberland PM, Martin NG, Sanfilippo PG, Lu Y, Wang YX, Hayward C, Polašek O, Campbell H, Bencic G, Wright AF, Wedenoja J, Zeller T, Schillert A, Mirshahi A, Lackner K, Yip SP, Yap MK, Ried JS, Gieger C, Murgia F, Wilson JF, Fleck B, Yazar S, Vingerling JR, Hofman A, Uitterlinden A, Rivadeneira F, Amin N, Karssen L, Oostra BA, Zhou X, Teo YY, Tai ES, Vithana E, Barathi V, Zheng Y, Siantar RG, Neelam K, Shin Y, Lam J, Yonova-Doing E, Venturini C, Hosseini SM, Wong HS, Lehtimäki T, Kähönen M, Raitakari O, Timpson NJ, Evans DM, Khor CC, Aung T, Young TL, Mitchell P, Klein B, van Duijn CM, Meitinger T, Jonas JB, Baird PN, Mackey DA, Wong TY, Saw SM, Pärssinen O, Stambolian D, Hammond CJ, Klaver CC, Williams C, Paterson AD, Bailey-Wilson JE, Guggenheim JA,
Human genetics134(2)131-46(2015 Feb)

CAS proteins in health and disease: an update.
Nikonova AS, Gaponova AV, Kudinov AE, Golemis EA
IUBMB life66(6)387-95(2014 Jun)

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F, , , , , Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannefelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltuenen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P
Nature genetics45(12)1452-8(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

High expression of CASS4 is associated with invasion in non-small cell lung cancer.
Title: Overexpression of CASS4 promotes invasion in non-small cell lung cancer by activating the AKT signaling pathway and inhibiting E-cadherin expression.

EFS and CASS4 protein function in the context of the larger CAS family group. [Review]
Title: Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members.

Hepl is overexpressed in the nucleus and aberrantly accumulates in the cytoplasm of non-small cell lung cancer cells, and Hepl may play a role in the progression of lung cancer, including lymph node metastasis and TNM stage.
Title: Overexpression and cytoplasmic accumulation of Hepl is associated with clinicopathological parameters and poor prognosis in non-small cell lung cancer.

HEPL maintains Cas family function in localization to focal adhesions, as well as regulation of FAK activity, focal adhesion integrity, and cell spreading.
Title: A novel Cas family member, HEPL, regulates FAK and cell spreading.

The following CASS4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CASS4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu26436 NM_001164115.1
Latest version!
Homo sapiens Cas scaffolding protein family member 4 (CASS4), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu26083 NM_001164114.1
Latest version!
Homo sapiens Cas scaffolding protein family member 4 (CASS4), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00
OHu26416 NM_001164116.1
Latest version!
Homo sapiens Cas scaffolding protein family member 4 (CASS4), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00
OHu26416 NM_020356.3
Latest version!
Homo sapiens Cas scaffolding protein family member 4 (CASS4), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00
OHu26083 XM_006723831.3
Latest version!
Homo sapiens Cas scaffolding protein family member 4 (CASS4), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu26436
Clone ID Related Accession (Same CDS sequence) NM_001164115.1
Accession Version NM_001164115.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1050bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-07
Organism Homo sapiens(Human)
Product cas scaffolding protein family member 4 isoform c
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA584687.1, AK027760.1 and AK295613.1. Transcript Variant: This variant (4) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: AK027760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAAGGGAA CAGGCATCAT GGACTGTGCG CCCAAGGCAC TCCTGGCCAG GGCACTTTAT 
GACAACTGCC CTGACTGCTC TGACGAGCTG GCTTTCAGCA GAGGGGACAT CCTGACCATT
CTGGAGCAAC ACGTGCCAGA AAGCGAGGGT TGGTGGAAGT GTTTGCTCCA TGGGAGGCAA
GGCCTGGCCC CTGCCAACCG CCTCCAAATC CTCACGGAGG TCGCTGCAGA CAGGCCGTGC
CCCCCATTCC TGAGAGGCCT GGAAGAAGCT CCTGCCAGCT CAGAGGAGAC CTATCAGGTG
CCCACTCTAC CCCGCCCTCC CACTCCAGGC CCCGTTTATG AGCAGATGAG GAGTTGGGCG
GAGGGGCCCC AGCCCCCTAC TGCCCAAGTC TATGAATTCC CCGACCCTCC CACCAGTGCC
AGAATCATCT GTGAAAAGAC TCTCAGCTTT CCAAAACAGG CCATCCTCAC GCTTCCCAGA
CCTGTCCGGG CCTCACTGCC GACTCTGCCT TCCCAGGTGT ATGACGTGCC TACCCAGCAC
CGGGGCCCCG TGGTCCTGAA GGAGCCAGAG AAGCAGCAGT TATATGACAT ACCAGCCAGC
CCCAAGAAGG CAGGACTCCA TCCCCCAGAC AGCCAAGCAA GTAATCCTGG CCCTCTTATA
CCTCAGCCTT CGAGTCAACA GACTCCTGAG AGGAAACCCC GCTTATCTGA ACACTGCCGG
CTCTACTTTG GGGCGCTCTT CAAAGCCATC AGCGCATTTC ACGGCAGCCT CAGCAGCAGC
CAGCCCGCGG AGATCATCAC TCAGAGCAAG CTGGTCATCA TGGTGGGACA GAAGCTGGTG
GACACGCTGT GCATGGAGAC CCAGGAGAGG GACGTGCGCA ACGAGATCCT CCGTGGCAGC
AGTCACCTCT GCAGCCTGCT CAAGGACGTA GCGCTGGCCA CTAAGAATGC CGTGCTCACG
TACCCCAGCC CTGCCGCGCT GGGGCACCTC CAGGCGGAGG CTGAGAAGCT GGAGCAACAC
ACGCGGCAGT TCAGAGGGAC ACTGGGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001157587.1
CDS202..1251
Misc Feature(1)163..165
Misc Feature(2)241..411
Misc Feature(3)order(259..261,265..267,274..276,286..288,349..354,391..393,397..402)
Misc Feature(4)799..801
Misc Feature(5)883..1248
Misc Feature(6)order(889..891,901..906,913..915,925..927,1009..1011,1018..1023,1030..1032,1039..1047,1054..1059,1099..1104,1111..1113,1123..1125,1132..1134,1144..1146)
Exon (1)1..237
Exon (2)238..660
Exon (3)661..762
Exon (4)763..843
Exon (5)844..1844
Translation

Target ORF information:

RefSeq Version NM_001164115.1
Organism Homo sapiens(Human)
Definition Homo sapiens Cas scaffolding protein family member 4 (CASS4), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164115.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAAGGGAA CAGGCATCAT GGACTGTGCG CCCAAGGCAC TCCTGGCCAG GGCACTTTAT 
GACAACTGCC CTGACTGCTC TGACGAGCTG GCTTTCAGCA GAGGGGACAT CCTGACCATT
CTGGAGCAAC ACGTGCCAGA AAGCGAGGGT TGGTGGAAGT GTTTGCTCCA TGGGAGGCAA
GGCCTGGCCC CTGCCAACCG CCTCCAAATC CTCACGGAGG TCGCTGCAGA CAGGCCGTGC
CCCCCATTCC TGAGAGGCCT GGAAGAAGCT CCTGCCAGCT CAGAGGAGAC CTATCAGGTG
CCCACTCTAC CCCGCCCTCC CACTCCAGGC CCCGTTTATG AGCAGATGAG GAGTTGGGCG
GAGGGGCCCC AGCCCCCTAC TGCCCAAGTC TATGAATTCC CCGACCCTCC CACCAGTGCC
AGAATCATCT GTGAAAAGAC TCTCAGCTTT CCAAAACAGG CCATCCTCAC GCTTCCCAGA
CCTGTCCGGG CCTCACTGCC GACTCTGCCT TCCCAGGTGT ATGACGTGCC TACCCAGCAC
CGGGGCCCCG TGGTCCTGAA GGAGCCAGAG AAGCAGCAGT TATATGACAT ACCAGCCAGC
CCCAAGAAGG CAGGACTCCA TCCCCCAGAC AGCCAAGCAA GTAATCCTGG CCCTCTTATA
CCTCAGCCTT CGAGTCAACA GACTCCTGAG AGGAAACCCC GCTTATCTGA ACACTGCCGG
CTCTACTTTG GGGCGCTCTT CAAAGCCATC AGCGCATTTC ACGGCAGCCT CAGCAGCAGC
CAGCCCGCGG AGATCATCAC TCAGAGCAAG CTGGTCATCA TGGTGGGACA GAAGCTGGTG
GACACGCTGT GCATGGAGAC CCAGGAGAGG GACGTGCGCA ACGAGATCCT CCGTGGCAGC
AGTCACCTCT GCAGCCTGCT CAAGGACGTA GCGCTGGCCA CTAAGAATGC CGTGCTCACG
TACCCCAGCC CTGCCGCGCT GGGGCACCTC CAGGCGGAGG CTGAGAAGCT GGAGCAACAC
ACGCGGCAGT TCAGAGGGAC ACTGGGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26083
Clone ID Related Accession (Same CDS sequence) XM_006723831.3 , NM_001164114.1
Accession Version NM_001164114.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2199bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-07
Organism Homo sapiens(Human)
Product cas scaffolding protein family member 4 isoform b
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA584687.1, AK295613.1 and AK027760.1. Transcript Variant: This variant (3) uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: AK295613.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGAAGGGAA CAGGCATCAT GGACTGTGCG CCCAAGGCAC TCCTGGCCAG GGCACTTTAT 
GACAACTGCC CTGACTGCTC TGACGAGCTG GCTTTCAGCA GAGGGGACAT CCTGACCATT
CTGGAGCAAC ACGTGCCAGA AAGCGAGGGT TGGTGGAAGT GTTTGCTCCA TGGGAGGCAA
GGCCTGGCCC CTGCCAACCG CCTCCAAATC CTCACGGAGG TCGCTGCAGA CAGGCCGTGC
CCCCCATTCC TGAGAGGCCT GGAAGAAGCT CCTGCCAGCT CAGAGGAGAC CTATCAGGCC
ATCCTCACGC TTCCCAGACC TGTCCGGGCC TCACTGCCGA CTCTGCCTTC CCAGGTGTAT
GACGTGCCTA CCCAGCACCG GGGCCCCGTG GTCCTGAAGG AGCCAGAGAA GCAGCAGTTA
TATGACATAC CAGCCAGCCC CAAGAAGGCA GGACTCCATC CCCCAGACAG CCAAGCAAGT
GGGCAGGGTG TTCCCCTGAT ATCAGTGACT ACCTTAAGAA GAGGCGGTTA CAGCACATTA
CCAAATCCTC AGAAATCGGA ATGGATTTAT GACACTCCAG TGTCTCCAGG AAAGGCCAGC
GTCAGAAACA CGCCTCTCAC CAGCTTTGCG GAAGAATCAA GGCCCCACGC TCTCCCCAGT
TCCAGCTCCA CTTTCTACAA TCCTCCAAGT GGCAGATCCA GGTCCCTCAC TCCACAACTG
AATAACAATG TGCCCATGCA GAAAAAACTC AGCCTTCCAG AAATTCCTTC TTATGGCTTT
CTTGTACCCA GAGGCACATT TCCTTTGGAT GAAGATGTCA GCTACAAGGT TCCTTCAAGC
TTTCTGATTC CCCGAGTGGA ACAGCAGAAC ACCAAGCCCA ATATTTATGA CATCCCTAAA
GCAACGTCGA GTGTTTCTCA GGCTGGGAAG GAGCTGGAGA AAGCCAAGGA GGTGTCAGAG
AATTCCGCGG GCCATAATTC CTCATGGTTC TCCAGACGGA CAACTTCCCC ATCTCCTGAA
CCGGACAGAT TATCAGGTTC CAGTTCTGAC AGCAGAGCTA GCATCGTTTC CTCGTGCTCC
ACCACATCCA CCGACGACTC CTCCAGCTCT TCCTCGGAGG AGTCAGCAAA GGAGCTCTCC
TTGGACCTGG ATGTGGCCAA GGAGACAGTG ATGGCTCTGC AGCACAAGGT GGTCAGCTCT
GTCGCTGGCC TGATGCTCTT TGTCAGCAGG AAGTGGAGAT TCCGAGACTA TCTGGAGGCC
AACATTGATG CAATCCACAG GTCCACTGAT CACATAGAAG AATCTGTAAG AGAATTTCTG
GATTTTGCCC GAGGAGTCCA TGGGACTGCC TGTAACCTCA CTGACAGTAA CCTTCAGAAC
AGAATTCGGG ACCAGATGCA GACCATCTCC AACTCCTACC GCATCCTGCT TGAAACAAAG
GAAAGCTTGG ATAATCGCAA TTGGCCTCTG GAAGTTCTTG TGACTGACAG TGTCCAGAAC
AGCCCAGATG ACCTTGAGAG GTTTGTCATG GTGGCACGGA TGCTTCCAGA AGACATCAAG
AGGTTTGCCT CCATTGTCAT TGCCAATGGA AGGCTCCTTT TTAAGCGGAA CTGTGAAAAG
GAAGAGACTG TGCAGTTGAC CCCAAATGCA GAATTTAAGT GTGAAAAATA CATCCAGCCT
CCCCAAAGAG AAACTGAATC ACACCAAAAG AGTACCCCTT CCACTAAGCA AAGGGAAGAT
GAACACTCTT CTGAACTATT AAAGAAAAAT AGGGCAAATA TCTGTGGACA GAATCCTGGC
CCTCTTATAC CTCAGCCTTC GAGTCAACAG ACTCCTGAGA GGAAACCCCG CTTATCTGAA
CACTGCCGGC TCTACTTTGG GGCGCTCTTC AAAGCCATCA GCGCATTTCA CGGCAGCCTC
AGCAGCAGCC AGCCCGCGGA GATCATCACT CAGAGCAAGC TGGTCATCAT GGTGGGACAG
AAGCTGGTGG ACACGCTGTG CATGGAGACC CAGGAGAGGG ACGTGCGCAA CGAGATCCTC
CGTGGCAGCA GTCACCTCTG CAGCCTGCTC AAGGACGTAG CGCTGGCCAC TAAGAATGCC
GTGCTCACGT ACCCCAGCCC TGCCGCGCTG GGGCACCTCC AGGCGGAGGC TGAGAAGCTG
GAGCAACACA CGCGGCAGTT CAGAGGGACA CTGGGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001157586.1
CDS202..2400
Misc Feature(1)163..165
Misc Feature(2)241..411
Misc Feature(3)order(259..261,265..267,274..276,286..288,349..354,391..393,397..402)
Misc Feature(4)1342..1818
Misc Feature(5)1822..2394
Misc Feature(6)order(2038..2040,2050..2055,2062..2064,2074..2076,2158..2160,2167..2172,2179..2181,2188..2196,2203..2208,2248..2253,2260..2262,2272..2274,2281..2283,2293..2295)
Exon (1)1..237
Exon (2)238..498
Exon (3)499..600
Exon (4)601..681
Exon (5)682..1992
Exon (6)1993..2993
Translation

Target ORF information:

RefSeq Version NM_001164114.1
Organism Homo sapiens(Human)
Definition Homo sapiens Cas scaffolding protein family member 4 (CASS4), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164114.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGAAGGGAA CAGGCATCAT GGACTGTGCG CCCAAGGCAC TCCTGGCCAG GGCACTTTAT 
GACAACTGCC CTGACTGCTC TGACGAGCTG GCTTTCAGCA GAGGGGACAT CCTGACCATT
CTGGAGCAAC ACGTGCCAGA AAGCGAGGGT TGGTGGAAGT GTTTGCTCCA TGGGAGGCAA
GGCCTGGCCC CTGCCAACCG CCTCCAAATC CTCACGGAGG TCGCTGCAGA CAGGCCGTGC
CCCCCATTCC TGAGAGGCCT GGAAGAAGCT CCTGCCAGCT CAGAGGAGAC CTATCAGGCC
ATCCTCACGC TTCCCAGACC TGTCCGGGCC TCACTGCCGA CTCTGCCTTC CCAGGTGTAT
GACGTGCCTA CCCAGCACCG GGGCCCCGTG GTCCTGAAGG AGCCAGAGAA GCAGCAGTTA
TATGACATAC CAGCCAGCCC CAAGAAGGCA GGACTCCATC CCCCAGACAG CCAAGCAAGT
GGGCAGGGTG TTCCCCTGAT ATCAGTGACT ACCTTAAGAA GAGGCGGTTA CAGCACATTA
CCAAATCCTC AGAAATCGGA ATGGATTTAT GACACTCCAG TGTCTCCAGG AAAGGCCAGC
GTCAGAAACA CGCCTCTCAC CAGCTTTGCG GAAGAATCAA GGCCCCACGC TCTCCCCAGT
TCCAGCTCCA CTTTCTACAA TCCTCCAAGT GGCAGATCCA GGTCCCTCAC TCCACAACTG
AATAACAATG TGCCCATGCA GAAAAAACTC AGCCTTCCAG AAATTCCTTC TTATGGCTTT
CTTGTACCCA GAGGCACATT TCCTTTGGAT GAAGATGTCA GCTACAAGGT TCCTTCAAGC
TTTCTGATTC CCCGAGTGGA ACAGCAGAAC ACCAAGCCCA ATATTTATGA CATCCCTAAA
GCAACGTCGA GTGTTTCTCA GGCTGGGAAG GAGCTGGAGA AAGCCAAGGA GGTGTCAGAG
AATTCCGCGG GCCATAATTC CTCATGGTTC TCCAGACGGA CAACTTCCCC ATCTCCTGAA
CCGGACAGAT TATCAGGTTC CAGTTCTGAC AGCAGAGCTA GCATCGTTTC CTCGTGCTCC
ACCACATCCA CCGACGACTC CTCCAGCTCT TCCTCGGAGG AGTCAGCAAA GGAGCTCTCC
TTGGACCTGG ATGTGGCCAA GGAGACAGTG ATGGCTCTGC AGCACAAGGT GGTCAGCTCT
GTCGCTGGCC TGATGCTCTT TGTCAGCAGG AAGTGGAGAT TCCGAGACTA TCTGGAGGCC
AACATTGATG CAATCCACAG GTCCACTGAT CACATAGAAG AATCTGTAAG AGAATTTCTG
GATTTTGCCC GAGGAGTCCA TGGGACTGCC TGTAACCTCA CTGACAGTAA CCTTCAGAAC
AGAATTCGGG ACCAGATGCA GACCATCTCC AACTCCTACC GCATCCTGCT TGAAACAAAG
GAAAGCTTGG ATAATCGCAA TTGGCCTCTG GAAGTTCTTG TGACTGACAG TGTCCAGAAC
AGCCCAGATG ACCTTGAGAG GTTTGTCATG GTGGCACGGA TGCTTCCAGA AGACATCAAG
AGGTTTGCCT CCATTGTCAT TGCCAATGGA AGGCTCCTTT TTAAGCGGAA CTGTGAAAAG
GAAGAGACTG TGCAGTTGAC CCCAAATGCA GAATTTAAGT GTGAAAAATA CATCCAGCCT
CCCCAAAGAG AAACTGAATC ACACCAAAAG AGTACCCCTT CCACTAAGCA AAGGGAAGAT
GAACACTCTT CTGAACTATT AAAGAAAAAT AGGGCAAATA TCTGTGGACA GAATCCTGGC
CCTCTTATAC CTCAGCCTTC GAGTCAACAG ACTCCTGAGA GGAAACCCCG CTTATCTGAA
CACTGCCGGC TCTACTTTGG GGCGCTCTTC AAAGCCATCA GCGCATTTCA CGGCAGCCTC
AGCAGCAGCC AGCCCGCGGA GATCATCACT CAGAGCAAGC TGGTCATCAT GGTGGGACAG
AAGCTGGTGG ACACGCTGTG CATGGAGACC CAGGAGAGGG ACGTGCGCAA CGAGATCCTC
CGTGGCAGCA GTCACCTCTG CAGCCTGCTC AAGGACGTAG CGCTGGCCAC TAAGAATGCC
GTGCTCACGT ACCCCAGCCC TGCCGCGCTG GGGCACCTCC AGGCGGAGGC TGAGAAGCTG
GAGCAACACA CGCGGCAGTT CAGAGGGACA CTGGGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26416
Clone ID Related Accession (Same CDS sequence) NM_020356.3 , NM_001164116.1
Accession Version NM_020356.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2361bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-07
Organism Homo sapiens(Human)
Product cas scaffolding protein family member 4 isoform a
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA584687.1, AK314653.1, AK295613.1 and AK027760.1. On Aug 12, 2009 this sequence version replaced NM_020356.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode isoform a. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.141160.1, SRR1803616.182557.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGAAGGGAA CAGGCATCAT GGACTGTGCG CCCAAGGCAC TCCTGGCCAG GGCACTTTAT 
GACAACTGCC CTGACTGCTC TGACGAGCTG GCTTTCAGCA GAGGGGACAT CCTGACCATT
CTGGAGCAAC ACGTGCCAGA AAGCGAGGGT TGGTGGAAGT GTTTGCTCCA TGGGAGGCAA
GGCCTGGCCC CTGCCAACCG CCTCCAAATC CTCACGGAGG TCGCTGCAGA CAGGCCGTGC
CCCCCATTCC TGAGAGGCCT GGAAGAAGCT CCTGCCAGCT CAGAGGAGAC CTATCAGGTG
CCCACTCTAC CCCGCCCTCC CACTCCAGGC CCCGTTTATG AGCAGATGAG GAGTTGGGCG
GAGGGGCCCC AGCCCCCTAC TGCCCAAGTC TATGAATTCC CCGACCCTCC CACCAGTGCC
AGAATCATCT GTGAAAAGAC TCTCAGCTTT CCAAAACAGG CCATCCTCAC GCTTCCCAGA
CCTGTCCGGG CCTCACTGCC GACTCTGCCT TCCCAGGTGT ATGACGTGCC TACCCAGCAC
CGGGGCCCCG TGGTCCTGAA GGAGCCAGAG AAGCAGCAGT TATATGACAT ACCAGCCAGC
CCCAAGAAGG CAGGACTCCA TCCCCCAGAC AGCCAAGCAA GTGGGCAGGG TGTTCCCCTG
ATATCAGTGA CTACCTTAAG AAGAGGCGGT TACAGCACAT TACCAAATCC TCAGAAATCG
GAATGGATTT ATGACACTCC AGTGTCTCCA GGAAAGGCCA GCGTCAGAAA CACGCCTCTC
ACCAGCTTTG CGGAAGAATC AAGGCCCCAC GCTCTCCCCA GTTCCAGCTC CACTTTCTAC
AATCCTCCAA GTGGCAGATC CAGGTCCCTC ACTCCACAAC TGAATAACAA TGTGCCCATG
CAGAAAAAAC TCAGCCTTCC AGAAATTCCT TCTTATGGCT TTCTTGTACC CAGAGGCACA
TTTCCTTTGG ATGAAGATGT CAGCTACAAG GTTCCTTCAA GCTTTCTGAT TCCCCGAGTG
GAACAGCAGA ACACCAAGCC CAATATTTAT GACATCCCTA AAGCAACGTC GAGTGTTTCT
CAGGCTGGGA AGGAGCTGGA GAAAGCCAAG GAGGTGTCAG AGAATTCCGC GGGCCATAAT
TCCTCATGGT TCTCCAGACG GACAACTTCC CCATCTCCTG AACCGGACAG ATTATCAGGT
TCCAGTTCTG ACAGCAGAGC TAGCATCGTT TCCTCGTGCT CCACCACATC CACCGACGAC
TCCTCCAGCT CTTCCTCGGA GGAGTCAGCA AAGGAGCTCT CCTTGGACCT GGATGTGGCC
AAGGAGACAG TGATGGCTCT GCAGCACAAG GTGGTCAGCT CTGTCGCTGG CCTGATGCTC
TTTGTCAGCA GGAAGTGGAG ATTCCGAGAC TATCTGGAGG CCAACATTGA TGCAATCCAC
AGGTCCACTG ATCACATAGA AGAATCTGTA AGAGAATTTC TGGATTTTGC CCGAGGAGTC
CATGGGACTG CCTGTAACCT CACTGACAGT AACCTTCAGA ACAGAATTCG GGACCAGATG
CAGACCATCT CCAACTCCTA CCGCATCCTG CTTGAAACAA AGGAAAGCTT GGATAATCGC
AATTGGCCTC TGGAAGTTCT TGTGACTGAC AGTGTCCAGA ACAGCCCAGA TGACCTTGAG
AGGTTTGTCA TGGTGGCACG GATGCTTCCA GAAGACATCA AGAGGTTTGC CTCCATTGTC
ATTGCCAATG GAAGGCTCCT TTTTAAGCGG AACTGTGAAA AGGAAGAGAC TGTGCAGTTG
ACCCCAAATG CAGAATTTAA GTGTGAAAAA TACATCCAGC CTCCCCAAAG AGAAACTGAA
TCACACCAAA AGAGTACCCC TTCCACTAAG CAAAGGGAAG ATGAACACTC TTCTGAACTA
TTAAAGAAAA ATAGGGCAAA TATCTGTGGA CAGAATCCTG GCCCTCTTAT ACCTCAGCCT
TCGAGTCAAC AGACTCCTGA GAGGAAACCC CGCTTATCTG AACACTGCCG GCTCTACTTT
GGGGCGCTCT TCAAAGCCAT CAGCGCATTT CACGGCAGCC TCAGCAGCAG CCAGCCCGCG
GAGATCATCA CTCAGAGCAA GCTGGTCATC ATGGTGGGAC AGAAGCTGGT GGACACGCTG
TGCATGGAGA CCCAGGAGAG GGACGTGCGC AACGAGATCC TCCGTGGCAG CAGTCACCTC
TGCAGCCTGC TCAAGGACGT AGCGCTGGCC ACTAAGAATG CCGTGCTCAC GTACCCCAGC
CCTGCCGCGC TGGGGCACCT CCAGGCGGAG GCTGAGAAGC TGGAGCAACA CACGCGGCAG
TTCAGAGGGA CACTGGGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_065089.2
CDS202..2562
Misc Feature(1)163..165
Misc Feature(2)241..411
Misc Feature(3)order(259..261,265..267,274..276,286..288,349..354,391..393,397..402)
Misc Feature(4)799..801
Misc Feature(5)946..948
Misc Feature(6)1114..1116
Misc Feature(7)1186..1188
Misc Feature(8)1249..1251
Misc Feature(9)1327..1329
Misc Feature(10)1369..1371
Misc Feature(11)1504..1980
Misc Feature(12)1984..2556
Misc Feature(13)order(2200..2202,2212..2217,2224..2226,2236..2238,2320..2322,2329..2334,2341..2343,2350..2358,2365..2370,2410..2415,2422..2424,2434..2436,2443..2445,2455..2457)
Exon (1)1..237
Exon (2)238..660
Exon (3)661..762
Exon (4)763..843
Exon (5)844..2154
Exon (6)2155..3155
Translation

Target ORF information:

RefSeq Version NM_020356.3
Organism Homo sapiens(Human)
Definition Homo sapiens Cas scaffolding protein family member 4 (CASS4), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_020356.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGAAGGGAA CAGGCATCAT GGACTGTGCG CCCAAGGCAC TCCTGGCCAG GGCACTTTAT 
GACAACTGCC CTGACTGCTC TGACGAGCTG GCTTTCAGCA GAGGGGACAT CCTGACCATT
CTGGAGCAAC ACGTGCCAGA AAGCGAGGGT TGGTGGAAGT GTTTGCTCCA TGGGAGGCAA
GGCCTGGCCC CTGCCAACCG CCTCCAAATC CTCACGGAGG TCGCTGCAGA CAGGCCGTGC
CCCCCATTCC TGAGAGGCCT GGAAGAAGCT CCTGCCAGCT CAGAGGAGAC CTATCAGGTG
CCCACTCTAC CCCGCCCTCC CACTCCAGGC CCCGTTTATG AGCAGATGAG GAGTTGGGCG
GAGGGGCCCC AGCCCCCTAC TGCCCAAGTC TATGAATTCC CCGACCCTCC CACCAGTGCC
AGAATCATCT GTGAAAAGAC TCTCAGCTTT CCAAAACAGG CCATCCTCAC GCTTCCCAGA
CCTGTCCGGG CCTCACTGCC GACTCTGCCT TCCCAGGTGT ATGACGTGCC TACCCAGCAC
CGGGGCCCCG TGGTCCTGAA GGAGCCAGAG AAGCAGCAGT TATATGACAT ACCAGCCAGC
CCCAAGAAGG CAGGACTCCA TCCCCCAGAC AGCCAAGCAA GTGGGCAGGG TGTTCCCCTG
ATATCAGTGA CTACCTTAAG AAGAGGCGGT TACAGCACAT TACCAAATCC TCAGAAATCG
GAATGGATTT ATGACACTCC AGTGTCTCCA GGAAAGGCCA GCGTCAGAAA CACGCCTCTC
ACCAGCTTTG CGGAAGAATC AAGGCCCCAC GCTCTCCCCA GTTCCAGCTC CACTTTCTAC
AATCCTCCAA GTGGCAGATC CAGGTCCCTC ACTCCACAAC TGAATAACAA TGTGCCCATG
CAGAAAAAAC TCAGCCTTCC AGAAATTCCT TCTTATGGCT TTCTTGTACC CAGAGGCACA
TTTCCTTTGG ATGAAGATGT CAGCTACAAG GTTCCTTCAA GCTTTCTGAT TCCCCGAGTG
GAACAGCAGA ACACCAAGCC CAATATTTAT GACATCCCTA AAGCAACGTC GAGTGTTTCT
CAGGCTGGGA AGGAGCTGGA GAAAGCCAAG GAGGTGTCAG AGAATTCCGC GGGCCATAAT
TCCTCATGGT TCTCCAGACG GACAACTTCC CCATCTCCTG AACCGGACAG ATTATCAGGT
TCCAGTTCTG ACAGCAGAGC TAGCATCGTT TCCTCGTGCT CCACCACATC CACCGACGAC
TCCTCCAGCT CTTCCTCGGA GGAGTCAGCA AAGGAGCTCT CCTTGGACCT GGATGTGGCC
AAGGAGACAG TGATGGCTCT GCAGCACAAG GTGGTCAGCT CTGTCGCTGG CCTGATGCTC
TTTGTCAGCA GGAAGTGGAG ATTCCGAGAC TATCTGGAGG CCAACATTGA TGCAATCCAC
AGGTCCACTG ATCACATAGA AGAATCTGTA AGAGAATTTC TGGATTTTGC CCGAGGAGTC
CATGGGACTG CCTGTAACCT CACTGACAGT AACCTTCAGA ACAGAATTCG GGACCAGATG
CAGACCATCT CCAACTCCTA CCGCATCCTG CTTGAAACAA AGGAAAGCTT GGATAATCGC
AATTGGCCTC TGGAAGTTCT TGTGACTGAC AGTGTCCAGA ACAGCCCAGA TGACCTTGAG
AGGTTTGTCA TGGTGGCACG GATGCTTCCA GAAGACATCA AGAGGTTTGC CTCCATTGTC
ATTGCCAATG GAAGGCTCCT TTTTAAGCGG AACTGTGAAA AGGAAGAGAC TGTGCAGTTG
ACCCCAAATG CAGAATTTAA GTGTGAAAAA TACATCCAGC CTCCCCAAAG AGAAACTGAA
TCACACCAAA AGAGTACCCC TTCCACTAAG CAAAGGGAAG ATGAACACTC TTCTGAACTA
TTAAAGAAAA ATAGGGCAAA TATCTGTGGA CAGAATCCTG GCCCTCTTAT ACCTCAGCCT
TCGAGTCAAC AGACTCCTGA GAGGAAACCC CGCTTATCTG AACACTGCCG GCTCTACTTT
GGGGCGCTCT TCAAAGCCAT CAGCGCATTT CACGGCAGCC TCAGCAGCAG CCAGCCCGCG
GAGATCATCA CTCAGAGCAA GCTGGTCATC ATGGTGGGAC AGAAGCTGGT GGACACGCTG
TGCATGGAGA CCCAGGAGAG GGACGTGCGC AACGAGATCC TCCGTGGCAG CAGTCACCTC
TGCAGCCTGC TCAAGGACGT AGCGCTGGCC ACTAAGAATG CCGTGCTCAC GTACCCCAGC
CCTGCCGCGC TGGGGCACCT CCAGGCGGAG GCTGAGAAGC TGGAGCAACA CACGCGGCAG
TTCAGAGGGA CACTGGGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26416
Clone ID Related Accession (Same CDS sequence) NM_020356.3 , NM_001164116.1
Accession Version NM_001164116.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2361bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-07
Organism Homo sapiens(Human)
Product cas scaffolding protein family member 4 isoform a
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ276678.1, AK314653.1, AK295613.1 and AK027760.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 both encode isoform a. ##Evidence-Data-START## Transcript exon combination :: AJ276678.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGAAGGGAA CAGGCATCAT GGACTGTGCG CCCAAGGCAC TCCTGGCCAG GGCACTTTAT 
GACAACTGCC CTGACTGCTC TGACGAGCTG GCTTTCAGCA GAGGGGACAT CCTGACCATT
CTGGAGCAAC ACGTGCCAGA AAGCGAGGGT TGGTGGAAGT GTTTGCTCCA TGGGAGGCAA
GGCCTGGCCC CTGCCAACCG CCTCCAAATC CTCACGGAGG TCGCTGCAGA CAGGCCGTGC
CCCCCATTCC TGAGAGGCCT GGAAGAAGCT CCTGCCAGCT CAGAGGAGAC CTATCAGGTG
CCCACTCTAC CCCGCCCTCC CACTCCAGGC CCCGTTTATG AGCAGATGAG GAGTTGGGCG
GAGGGGCCCC AGCCCCCTAC TGCCCAAGTC TATGAATTCC CCGACCCTCC CACCAGTGCC
AGAATCATCT GTGAAAAGAC TCTCAGCTTT CCAAAACAGG CCATCCTCAC GCTTCCCAGA
CCTGTCCGGG CCTCACTGCC GACTCTGCCT TCCCAGGTGT ATGACGTGCC TACCCAGCAC
CGGGGCCCCG TGGTCCTGAA GGAGCCAGAG AAGCAGCAGT TATATGACAT ACCAGCCAGC
CCCAAGAAGG CAGGACTCCA TCCCCCAGAC AGCCAAGCAA GTGGGCAGGG TGTTCCCCTG
ATATCAGTGA CTACCTTAAG AAGAGGCGGT TACAGCACAT TACCAAATCC TCAGAAATCG
GAATGGATTT ATGACACTCC AGTGTCTCCA GGAAAGGCCA GCGTCAGAAA CACGCCTCTC
ACCAGCTTTG CGGAAGAATC AAGGCCCCAC GCTCTCCCCA GTTCCAGCTC CACTTTCTAC
AATCCTCCAA GTGGCAGATC CAGGTCCCTC ACTCCACAAC TGAATAACAA TGTGCCCATG
CAGAAAAAAC TCAGCCTTCC AGAAATTCCT TCTTATGGCT TTCTTGTACC CAGAGGCACA
TTTCCTTTGG ATGAAGATGT CAGCTACAAG GTTCCTTCAA GCTTTCTGAT TCCCCGAGTG
GAACAGCAGA ACACCAAGCC CAATATTTAT GACATCCCTA AAGCAACGTC GAGTGTTTCT
CAGGCTGGGA AGGAGCTGGA GAAAGCCAAG GAGGTGTCAG AGAATTCCGC GGGCCATAAT
TCCTCATGGT TCTCCAGACG GACAACTTCC CCATCTCCTG AACCGGACAG ATTATCAGGT
TCCAGTTCTG ACAGCAGAGC TAGCATCGTT TCCTCGTGCT CCACCACATC CACCGACGAC
TCCTCCAGCT CTTCCTCGGA GGAGTCAGCA AAGGAGCTCT CCTTGGACCT GGATGTGGCC
AAGGAGACAG TGATGGCTCT GCAGCACAAG GTGGTCAGCT CTGTCGCTGG CCTGATGCTC
TTTGTCAGCA GGAAGTGGAG ATTCCGAGAC TATCTGGAGG CCAACATTGA TGCAATCCAC
AGGTCCACTG ATCACATAGA AGAATCTGTA AGAGAATTTC TGGATTTTGC CCGAGGAGTC
CATGGGACTG CCTGTAACCT CACTGACAGT AACCTTCAGA ACAGAATTCG GGACCAGATG
CAGACCATCT CCAACTCCTA CCGCATCCTG CTTGAAACAA AGGAAAGCTT GGATAATCGC
AATTGGCCTC TGGAAGTTCT TGTGACTGAC AGTGTCCAGA ACAGCCCAGA TGACCTTGAG
AGGTTTGTCA TGGTGGCACG GATGCTTCCA GAAGACATCA AGAGGTTTGC CTCCATTGTC
ATTGCCAATG GAAGGCTCCT TTTTAAGCGG AACTGTGAAA AGGAAGAGAC TGTGCAGTTG
ACCCCAAATG CAGAATTTAA GTGTGAAAAA TACATCCAGC CTCCCCAAAG AGAAACTGAA
TCACACCAAA AGAGTACCCC TTCCACTAAG CAAAGGGAAG ATGAACACTC TTCTGAACTA
TTAAAGAAAA ATAGGGCAAA TATCTGTGGA CAGAATCCTG GCCCTCTTAT ACCTCAGCCT
TCGAGTCAAC AGACTCCTGA GAGGAAACCC CGCTTATCTG AACACTGCCG GCTCTACTTT
GGGGCGCTCT TCAAAGCCAT CAGCGCATTT CACGGCAGCC TCAGCAGCAG CCAGCCCGCG
GAGATCATCA CTCAGAGCAA GCTGGTCATC ATGGTGGGAC AGAAGCTGGT GGACACGCTG
TGCATGGAGA CCCAGGAGAG GGACGTGCGC AACGAGATCC TCCGTGGCAG CAGTCACCTC
TGCAGCCTGC TCAAGGACGT AGCGCTGGCC ACTAAGAATG CCGTGCTCAC GTACCCCAGC
CCTGCCGCGC TGGGGCACCT CCAGGCGGAG GCTGAGAAGC TGGAGCAACA CACGCGGCAG
TTCAGAGGGA CACTGGGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001157588.1
CDS226..2586
Misc Feature(1)187..189
Misc Feature(2)265..435
Misc Feature(3)order(283..285,289..291,298..300,310..312,373..378,415..417,421..426)
Misc Feature(4)823..825
Misc Feature(5)970..972
Misc Feature(6)1138..1140
Misc Feature(7)1351..1353
Misc Feature(8)1393..1395
Misc Feature(9)1528..2004
Misc Feature(10)2008..2580
Misc Feature(11)order(2224..2226,2236..2241,2248..2250,2260..2262,2344..2346,2353..2358,2365..2367,2374..2382,2389..2394,2434..2439,2446..2448,2458..2460,2467..2469,2479..2481)
Exon (1)1..103
Exon (2)104..261
Exon (3)262..684
Exon (4)685..786
Exon (5)787..867
Exon (6)868..2178
Exon (7)2179..3179
Translation

Target ORF information:

RefSeq Version NM_001164116.1
Organism Homo sapiens(Human)
Definition Homo sapiens Cas scaffolding protein family member 4 (CASS4), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164116.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGAAGGGAA CAGGCATCAT GGACTGTGCG CCCAAGGCAC TCCTGGCCAG GGCACTTTAT 
GACAACTGCC CTGACTGCTC TGACGAGCTG GCTTTCAGCA GAGGGGACAT CCTGACCATT
CTGGAGCAAC ACGTGCCAGA AAGCGAGGGT TGGTGGAAGT GTTTGCTCCA TGGGAGGCAA
GGCCTGGCCC CTGCCAACCG CCTCCAAATC CTCACGGAGG TCGCTGCAGA CAGGCCGTGC
CCCCCATTCC TGAGAGGCCT GGAAGAAGCT CCTGCCAGCT CAGAGGAGAC CTATCAGGTG
CCCACTCTAC CCCGCCCTCC CACTCCAGGC CCCGTTTATG AGCAGATGAG GAGTTGGGCG
GAGGGGCCCC AGCCCCCTAC TGCCCAAGTC TATGAATTCC CCGACCCTCC CACCAGTGCC
AGAATCATCT GTGAAAAGAC TCTCAGCTTT CCAAAACAGG CCATCCTCAC GCTTCCCAGA
CCTGTCCGGG CCTCACTGCC GACTCTGCCT TCCCAGGTGT ATGACGTGCC TACCCAGCAC
CGGGGCCCCG TGGTCCTGAA GGAGCCAGAG AAGCAGCAGT TATATGACAT ACCAGCCAGC
CCCAAGAAGG CAGGACTCCA TCCCCCAGAC AGCCAAGCAA GTGGGCAGGG TGTTCCCCTG
ATATCAGTGA CTACCTTAAG AAGAGGCGGT TACAGCACAT TACCAAATCC TCAGAAATCG
GAATGGATTT ATGACACTCC AGTGTCTCCA GGAAAGGCCA GCGTCAGAAA CACGCCTCTC
ACCAGCTTTG CGGAAGAATC AAGGCCCCAC GCTCTCCCCA GTTCCAGCTC CACTTTCTAC
AATCCTCCAA GTGGCAGATC CAGGTCCCTC ACTCCACAAC TGAATAACAA TGTGCCCATG
CAGAAAAAAC TCAGCCTTCC AGAAATTCCT TCTTATGGCT TTCTTGTACC CAGAGGCACA
TTTCCTTTGG ATGAAGATGT CAGCTACAAG GTTCCTTCAA GCTTTCTGAT TCCCCGAGTG
GAACAGCAGA ACACCAAGCC CAATATTTAT GACATCCCTA AAGCAACGTC GAGTGTTTCT
CAGGCTGGGA AGGAGCTGGA GAAAGCCAAG GAGGTGTCAG AGAATTCCGC GGGCCATAAT
TCCTCATGGT TCTCCAGACG GACAACTTCC CCATCTCCTG AACCGGACAG ATTATCAGGT
TCCAGTTCTG ACAGCAGAGC TAGCATCGTT TCCTCGTGCT CCACCACATC CACCGACGAC
TCCTCCAGCT CTTCCTCGGA GGAGTCAGCA AAGGAGCTCT CCTTGGACCT GGATGTGGCC
AAGGAGACAG TGATGGCTCT GCAGCACAAG GTGGTCAGCT CTGTCGCTGG CCTGATGCTC
TTTGTCAGCA GGAAGTGGAG ATTCCGAGAC TATCTGGAGG CCAACATTGA TGCAATCCAC
AGGTCCACTG ATCACATAGA AGAATCTGTA AGAGAATTTC TGGATTTTGC CCGAGGAGTC
CATGGGACTG CCTGTAACCT CACTGACAGT AACCTTCAGA ACAGAATTCG GGACCAGATG
CAGACCATCT CCAACTCCTA CCGCATCCTG CTTGAAACAA AGGAAAGCTT GGATAATCGC
AATTGGCCTC TGGAAGTTCT TGTGACTGAC AGTGTCCAGA ACAGCCCAGA TGACCTTGAG
AGGTTTGTCA TGGTGGCACG GATGCTTCCA GAAGACATCA AGAGGTTTGC CTCCATTGTC
ATTGCCAATG GAAGGCTCCT TTTTAAGCGG AACTGTGAAA AGGAAGAGAC TGTGCAGTTG
ACCCCAAATG CAGAATTTAA GTGTGAAAAA TACATCCAGC CTCCCCAAAG AGAAACTGAA
TCACACCAAA AGAGTACCCC TTCCACTAAG CAAAGGGAAG ATGAACACTC TTCTGAACTA
TTAAAGAAAA ATAGGGCAAA TATCTGTGGA CAGAATCCTG GCCCTCTTAT ACCTCAGCCT
TCGAGTCAAC AGACTCCTGA GAGGAAACCC CGCTTATCTG AACACTGCCG GCTCTACTTT
GGGGCGCTCT TCAAAGCCAT CAGCGCATTT CACGGCAGCC TCAGCAGCAG CCAGCCCGCG
GAGATCATCA CTCAGAGCAA GCTGGTCATC ATGGTGGGAC AGAAGCTGGT GGACACGCTG
TGCATGGAGA CCCAGGAGAG GGACGTGCGC AACGAGATCC TCCGTGGCAG CAGTCACCTC
TGCAGCCTGC TCAAGGACGT AGCGCTGGCC ACTAAGAATG CCGTGCTCAC GTACCCCAGC
CCTGCCGCGC TGGGGCACCT CCAGGCGGAG GCTGAGAAGC TGGAGCAACA CACGCGGCAG
TTCAGAGGGA CACTGGGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26083
Clone ID Related Accession (Same CDS sequence) XM_006723831.3 , NM_001164114.1
Accession Version XM_006723831.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2199bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product cas scaffolding protein family member 4 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006723831.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGAAGGGAA CAGGCATCAT GGACTGTGCG CCCAAGGCAC TCCTGGCCAG GGCACTTTAT 
GACAACTGCC CTGACTGCTC TGACGAGCTG GCTTTCAGCA GAGGGGACAT CCTGACCATT
CTGGAGCAAC ACGTGCCAGA AAGCGAGGGT TGGTGGAAGT GTTTGCTCCA TGGGAGGCAA
GGCCTGGCCC CTGCCAACCG CCTCCAAATC CTCACGGAGG TCGCTGCAGA CAGGCCGTGC
CCCCCATTCC TGAGAGGCCT GGAAGAAGCT CCTGCCAGCT CAGAGGAGAC CTATCAGGCC
ATCCTCACGC TTCCCAGACC TGTCCGGGCC TCACTGCCGA CTCTGCCTTC CCAGGTGTAT
GACGTGCCTA CCCAGCACCG GGGCCCCGTG GTCCTGAAGG AGCCAGAGAA GCAGCAGTTA
TATGACATAC CAGCCAGCCC CAAGAAGGCA GGACTCCATC CCCCAGACAG CCAAGCAAGT
GGGCAGGGTG TTCCCCTGAT ATCAGTGACT ACCTTAAGAA GAGGCGGTTA CAGCACATTA
CCAAATCCTC AGAAATCGGA ATGGATTTAT GACACTCCAG TGTCTCCAGG AAAGGCCAGC
GTCAGAAACA CGCCTCTCAC CAGCTTTGCG GAAGAATCAA GGCCCCACGC TCTCCCCAGT
TCCAGCTCCA CTTTCTACAA TCCTCCAAGT GGCAGATCCA GGTCCCTCAC TCCACAACTG
AATAACAATG TGCCCATGCA GAAAAAACTC AGCCTTCCAG AAATTCCTTC TTATGGCTTT
CTTGTACCCA GAGGCACATT TCCTTTGGAT GAAGATGTCA GCTACAAGGT TCCTTCAAGC
TTTCTGATTC CCCGAGTGGA ACAGCAGAAC ACCAAGCCCA ATATTTATGA CATCCCTAAA
GCAACGTCGA GTGTTTCTCA GGCTGGGAAG GAGCTGGAGA AAGCCAAGGA GGTGTCAGAG
AATTCCGCGG GCCATAATTC CTCATGGTTC TCCAGACGGA CAACTTCCCC ATCTCCTGAA
CCGGACAGAT TATCAGGTTC CAGTTCTGAC AGCAGAGCTA GCATCGTTTC CTCGTGCTCC
ACCACATCCA CCGACGACTC CTCCAGCTCT TCCTCGGAGG AGTCAGCAAA GGAGCTCTCC
TTGGACCTGG ATGTGGCCAA GGAGACAGTG ATGGCTCTGC AGCACAAGGT GGTCAGCTCT
GTCGCTGGCC TGATGCTCTT TGTCAGCAGG AAGTGGAGAT TCCGAGACTA TCTGGAGGCC
AACATTGATG CAATCCACAG GTCCACTGAT CACATAGAAG AATCTGTAAG AGAATTTCTG
GATTTTGCCC GAGGAGTCCA TGGGACTGCC TGTAACCTCA CTGACAGTAA CCTTCAGAAC
AGAATTCGGG ACCAGATGCA GACCATCTCC AACTCCTACC GCATCCTGCT TGAAACAAAG
GAAAGCTTGG ATAATCGCAA TTGGCCTCTG GAAGTTCTTG TGACTGACAG TGTCCAGAAC
AGCCCAGATG ACCTTGAGAG GTTTGTCATG GTGGCACGGA TGCTTCCAGA AGACATCAAG
AGGTTTGCCT CCATTGTCAT TGCCAATGGA AGGCTCCTTT TTAAGCGGAA CTGTGAAAAG
GAAGAGACTG TGCAGTTGAC CCCAAATGCA GAATTTAAGT GTGAAAAATA CATCCAGCCT
CCCCAAAGAG AAACTGAATC ACACCAAAAG AGTACCCCTT CCACTAAGCA AAGGGAAGAT
GAACACTCTT CTGAACTATT AAAGAAAAAT AGGGCAAATA TCTGTGGACA GAATCCTGGC
CCTCTTATAC CTCAGCCTTC GAGTCAACAG ACTCCTGAGA GGAAACCCCG CTTATCTGAA
CACTGCCGGC TCTACTTTGG GGCGCTCTTC AAAGCCATCA GCGCATTTCA CGGCAGCCTC
AGCAGCAGCC AGCCCGCGGA GATCATCACT CAGAGCAAGC TGGTCATCAT GGTGGGACAG
AAGCTGGTGG ACACGCTGTG CATGGAGACC CAGGAGAGGG ACGTGCGCAA CGAGATCCTC
CGTGGCAGCA GTCACCTCTG CAGCCTGCTC AAGGACGTAG CGCTGGCCAC TAAGAATGCC
GTGCTCACGT ACCCCAGCCC TGCCGCGCTG GGGCACCTCC AGGCGGAGGC TGAGAAGCTG
GAGCAACACA CGCGGCAGTT CAGAGGGACA CTGGGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006723894.1
CDS788..2986
Misc Feature(1)827..997
Misc Feature(2)order(845..847,851..853,860..862,872..874,935..940,977..979,983..988)
Misc Feature(3)1928..2404
Misc Feature(4)2408..2980
Misc Feature(5)order(2624..2626,2636..2641,2648..2650,2660..2662,2744..2746,2753..2758,2765..2767,2774..2782,2789..2794,2834..2839,2846..2848,2858..2860,2867..2869,2879..2881)
Translation

Target ORF information:

RefSeq Version XM_006723831.3
Organism Homo sapiens(Human)
Definition Homo sapiens Cas scaffolding protein family member 4 (CASS4), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006723831.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGAAGGGAA CAGGCATCAT GGACTGTGCG CCCAAGGCAC TCCTGGCCAG GGCACTTTAT 
GACAACTGCC CTGACTGCTC TGACGAGCTG GCTTTCAGCA GAGGGGACAT CCTGACCATT
CTGGAGCAAC ACGTGCCAGA AAGCGAGGGT TGGTGGAAGT GTTTGCTCCA TGGGAGGCAA
GGCCTGGCCC CTGCCAACCG CCTCCAAATC CTCACGGAGG TCGCTGCAGA CAGGCCGTGC
CCCCCATTCC TGAGAGGCCT GGAAGAAGCT CCTGCCAGCT CAGAGGAGAC CTATCAGGCC
ATCCTCACGC TTCCCAGACC TGTCCGGGCC TCACTGCCGA CTCTGCCTTC CCAGGTGTAT
GACGTGCCTA CCCAGCACCG GGGCCCCGTG GTCCTGAAGG AGCCAGAGAA GCAGCAGTTA
TATGACATAC CAGCCAGCCC CAAGAAGGCA GGACTCCATC CCCCAGACAG CCAAGCAAGT
GGGCAGGGTG TTCCCCTGAT ATCAGTGACT ACCTTAAGAA GAGGCGGTTA CAGCACATTA
CCAAATCCTC AGAAATCGGA ATGGATTTAT GACACTCCAG TGTCTCCAGG AAAGGCCAGC
GTCAGAAACA CGCCTCTCAC CAGCTTTGCG GAAGAATCAA GGCCCCACGC TCTCCCCAGT
TCCAGCTCCA CTTTCTACAA TCCTCCAAGT GGCAGATCCA GGTCCCTCAC TCCACAACTG
AATAACAATG TGCCCATGCA GAAAAAACTC AGCCTTCCAG AAATTCCTTC TTATGGCTTT
CTTGTACCCA GAGGCACATT TCCTTTGGAT GAAGATGTCA GCTACAAGGT TCCTTCAAGC
TTTCTGATTC CCCGAGTGGA ACAGCAGAAC ACCAAGCCCA ATATTTATGA CATCCCTAAA
GCAACGTCGA GTGTTTCTCA GGCTGGGAAG GAGCTGGAGA AAGCCAAGGA GGTGTCAGAG
AATTCCGCGG GCCATAATTC CTCATGGTTC TCCAGACGGA CAACTTCCCC ATCTCCTGAA
CCGGACAGAT TATCAGGTTC CAGTTCTGAC AGCAGAGCTA GCATCGTTTC CTCGTGCTCC
ACCACATCCA CCGACGACTC CTCCAGCTCT TCCTCGGAGG AGTCAGCAAA GGAGCTCTCC
TTGGACCTGG ATGTGGCCAA GGAGACAGTG ATGGCTCTGC AGCACAAGGT GGTCAGCTCT
GTCGCTGGCC TGATGCTCTT TGTCAGCAGG AAGTGGAGAT TCCGAGACTA TCTGGAGGCC
AACATTGATG CAATCCACAG GTCCACTGAT CACATAGAAG AATCTGTAAG AGAATTTCTG
GATTTTGCCC GAGGAGTCCA TGGGACTGCC TGTAACCTCA CTGACAGTAA CCTTCAGAAC
AGAATTCGGG ACCAGATGCA GACCATCTCC AACTCCTACC GCATCCTGCT TGAAACAAAG
GAAAGCTTGG ATAATCGCAA TTGGCCTCTG GAAGTTCTTG TGACTGACAG TGTCCAGAAC
AGCCCAGATG ACCTTGAGAG GTTTGTCATG GTGGCACGGA TGCTTCCAGA AGACATCAAG
AGGTTTGCCT CCATTGTCAT TGCCAATGGA AGGCTCCTTT TTAAGCGGAA CTGTGAAAAG
GAAGAGACTG TGCAGTTGAC CCCAAATGCA GAATTTAAGT GTGAAAAATA CATCCAGCCT
CCCCAAAGAG AAACTGAATC ACACCAAAAG AGTACCCCTT CCACTAAGCA AAGGGAAGAT
GAACACTCTT CTGAACTATT AAAGAAAAAT AGGGCAAATA TCTGTGGACA GAATCCTGGC
CCTCTTATAC CTCAGCCTTC GAGTCAACAG ACTCCTGAGA GGAAACCCCG CTTATCTGAA
CACTGCCGGC TCTACTTTGG GGCGCTCTTC AAAGCCATCA GCGCATTTCA CGGCAGCCTC
AGCAGCAGCC AGCCCGCGGA GATCATCACT CAGAGCAAGC TGGTCATCAT GGTGGGACAG
AAGCTGGTGG ACACGCTGTG CATGGAGACC CAGGAGAGGG ACGTGCGCAA CGAGATCCTC
CGTGGCAGCA GTCACCTCTG CAGCCTGCTC AAGGACGTAG CGCTGGCCAC TAAGAATGCC
GTGCTCACGT ACCCCAGCCC TGCCGCGCTG GGGCACCTCC AGGCGGAGGC TGAGAAGCTG
GAGCAACACA CGCGGCAGTT CAGAGGGACA CTGGGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Overexpression of CASS4 promotes invasion in non-small cell lung cancer by activating the AKT signaling pathway and inhibiting E-cadherin expression.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(11)15157-15164(2016 Nov)
Li A,Zhang W,Xia H,Miao Y,Zhou H,Zhang X,Dong Q,Li Q,Qiu X,Wang E


book

Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members.
Gene570(1)25-35(2015 Oct)
Deneka A,Korobeynikov V,Golemis EA


book

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.
Human genetics134(2)131-46(2015 Feb)
Li Q,Wojciechowski R,Simpson CL,Hysi PG,Verhoeven VJ,Ikram MK,Höhn R,Vitart V,Hewitt AW,Oexle K,Mäkelä KM,MacGregor S,Pirastu M,Fan Q,Cheng CY,St Pourcain B,McMahon G,Kemp JP,Northstone K,Rahi JS,Cumberland PM,Martin NG,Sanfilippo PG,Lu Y,Wang YX,Hayward C,Polašek O,Campbell H,Bencic G,Wright AF,Wedenoja J,Zeller T,Schillert A,Mirshahi A,Lackner K,Yip SP,Yap MK,Ried JS,Gieger C,Murgia F,Wilson JF,Fleck B,Yazar S,Vingerling JR,Hofman A,Uitterlinden A,Rivadeneira F,Amin N,Karssen L,Oostra BA,Zhou X,Teo YY,Tai ES,Vithana E,Barathi V,Zheng Y,Siantar RG,Neelam K,Shin Y,Lam J,Yonova-Doing E,Venturini C,Hosseini SM,Wong HS,Lehtimäki T,Kähönen M,Raitakari O,Timpson NJ,Evans DM,Khor CC,Aung T,Young TL,Mitchell P,Klein B,van Duijn CM,Meitinger T,Jonas JB,Baird PN,Mackey DA,Wong TY,Saw SM,Pärssinen O,Stambolian D,Hammond CJ,Klaver CC,Williams C,Paterson AD,Bailey-Wilson JE,Guggenheim JA,


book

CAS proteins in health and disease: an update.
IUBMB life66(6)387-95(2014 Jun)
Nikonova AS,Gaponova AV,Kudinov AE,Golemis EA


book

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Nature genetics45(12)1452-8(2013 Dec)
Lambert JC,Ibrahim-Verbaas CA,Harold D,Naj AC,Sims R,Bellenguez C,DeStafano AL,Bis JC,Beecham GW,Grenier-Boley B,Russo G,Thorton-Wells TA,Jones N,Smith AV,Chouraki V,Thomas C,Ikram MA,Zelenika D,Vardarajan BN,Kamatani Y,Lin CF,Gerrish A,Schmidt H,Kunkle B,Dunstan ML,Ruiz A,Bihoreau MT,Choi SH,Reitz C,Pasquier F,Cruchaga C,Craig D,Amin N,Berr C,Lopez OL,De Jager PL,Deramecourt V,Johnston JA,Evans D,Lovestone S,Letenneur L,Morón FJ,Rubinsztein DC,Eiriksdottir G,Sleegers K,Goate AM,Fiévet N,Huentelman MW,Gill M,Brown K,Kamboh MI,Keller L,Barberger-Gateau P,McGuiness B,Larson EB,Green R,Myers AJ,Dufouil C,Todd S,Wallon D,Love S,Rogaeva E,Gallacher J,St George-Hyslop P,Clarimon J,Lleo A,Bayer A,Tsuang DW,Yu L,Tsolaki M,Bossù P,Spalletta G,Proitsi P,Collinge J,Sorbi S,Sanchez-Garcia F,Fox NC,Hardy J,Deniz Naranjo MC,Bosco P,Clarke R,Brayne C,Galimberti D,Mancuso M,Matthews F,,,,,Moebus S,Mecocci P,Del Zompo M,Maier W,Hampel H,Pilotto A,Bullido M,Panza F,Caffarra P,Nacmias B,Gilbert JR,Mayhaus M,Lannefelt L,Hakonarson H,Pichler S,Carrasquillo MM,Ingelsson M,Beekly D,Alvarez V,Zou F,Valladares O,Younkin SG,Coto E,Hamilton-Nelson KL,Gu W,Razquin C,Pastor P,Mateo I,Owen MJ,Faber KM,Jonsson PV,Combarros O,O'Donovan MC,Cantwell LB,Soininen H,Blacker D,Mead S,Mosley TH Jr,Bennett DA,Harris TB,Fratiglioni L,Holmes C,de Bruijn RF,Passmore P,Montine TJ,Bettens K,Rotter JI,Brice A,Morgan K,Foroud TM,Kukull WA,Hannequin D,Powell JF,Nalls MA,Ritchie K,Lunetta KL,Kauwe JS,Boerwinkle E,Riemenschneider M,Boada M,Hiltuenen M,Martin ER,Schmidt R,Rujescu D,Wang LS,Dartigues JF,Mayeux R,Tzourio C,Hofman A,Nöthen MM,Graff C,Psaty BM,Jones L,Haines JL,Holmans PA,Lathrop M,Pericak-Vance MA,Launer LJ,Farrer LA,van Duijn CM,Van Broeckhoven C,Moskvina V,Seshadri S,Williams J,Schellenberg GD,Amouyel P


 
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