PTGIR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PTGIR
Entrez Gene ID	5739
Full Name	prostaglandin I2 receptor
Synonyms	IP,PRIPR
General protein information	Preferred Names prostaglandin I2 receptor Names prostacyclin receptor PGI receptor PGI2 receptor prostaglandin I2 (prostacyclin) receptor (IP) prostanoid IP receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.32
Summary	The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008].
Disorder MIM:	600022

mRNA and Protein(s)

mRNA	Protein	Name
XM_005259095.3	XP_005259152.1	prostacyclin receptor isoform X2
XM_005259093.2	XP_005259150.1	prostacyclin receptor isoform X1
NM_000960.4	NP_000951.1	prostacyclin receptor
NM_000960.3	NP_000951.1	prostacyclin receptor
XM_005259093.3	XP_005259150.1	prostacyclin receptor isoform X1
XM_005259095.4	XP_005259152.1	prostacyclin receptor isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PTGIR	XP_003316506.1
	PTGIR	XP_001112077.1
Mus musculus (house mouse)	Ptgir	NP_032993.2
Homo sapiens (human)	PTGIR	NP_000951.1
Canis lupus familiaris (dog)	PTGIR	XP_541544.2
Danio rerio (zebrafish)	LOC561406	XP_689903.3
Xenopus tropicalis (tropical clawed frog)	ptgir	XP_002932677.1
Rattus norvegicus (Norway rat)	Ptgir	NP_001071112.1
Bos taurus (cattle)	PTGIR	NP_001015622.2

Gene Ontology
Bibliography

Related articles in PubMed

Identification of ?-helix 4 (?4) of Rab11a as a novel Rab11-binding domain (RBD): Interaction of Rab11a with the Prostacyclin Receptor.
Mulvaney EP, O'Meara F, Khan AR, O'Connell DJ, Kinsella BT
Biochimica et biophysica acta1864(10)1819-1832(2017 10)

Role of prostacyclin signaling in endothelial production of soluble amyloid precursor protein-? in cerebral microvessels.
He T, Santhanam AV, Lu T, d'Uscio LV, Katusic ZS
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism37(1)106-122(2017 Jan)

Regulated expression of the prostacyclin receptor (IP) gene by androgens within the vasculature: Combined role for androgens and serum cholesterol.
Eivers SB, Kinsella BT
Biochimica et biophysica acta1859(10)1333-51(2016 10)

Prostaglandin I2 Receptor Agonism Preserves ?-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms.
Batchu SN, Majumder S, Bowskill BB, White KE, Advani SL, Brijmohan AS, Liu Y, Thai K, Azizi PM, Lee WL, Advani A
Diabetes65(5)1398-409(2016 05)

IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin.
Ghandour RA, Giroud M, Vegiopoulos A, Herzig S, Ailhaud G, Amri EZ, Pisani DF
Biochimica et biophysica acta1861(4)285-93(2016 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these studies are not only the first to identify alpha4 helix of Rab11a as a protein binding domain on the GTPase but also reveal novel mechanistic insights into the intracellular trafficking of the human prostacyclin receptor (hIP), and potentially of other members of the GPCR superfamily, involving Rab11-dependent mechanisms.
Title: Identification of ?-helix 4 (?4) of Rab11a as a novel Rab11-binding domain (RBD): Interaction of Rab11a with the Prostacyclin Receptor.

role of IP-PPARdelta signal transduction pathway in the production of sAPPalpha in cerebral microvasculature.
Title: Role of prostacyclin signaling in endothelial production of soluble amyloid precursor protein-? in cerebral microvessels.

The human prostacyclin receptor gene is under the transcriptional regulation of dihydrotestosterone, where this regulation is further influenced by serum-cholesterol levels.
Title: Regulated expression of the prostacyclin receptor (IP) gene by androgens within the vasculature: Combined role for androgens and serum cholesterol.

Data (including data from studies using transgenic mice, an murine experimental model of diabetes, and mouse/human cell lines) suggest prostaglandin I2 receptor (PTGIR) is involved in insulin secretion in pancreatic beta-cells and in permselectivity in glomerular podocytes; the mechanism appears to involve regulation of post-translational phosphorylation of nephrin.
Title: Prostaglandin I2 Receptor Agonism Preserves ?-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms.

cPGI2 generates via its cognate cell-surface receptor IP-R, converting white adipocytes to brite adipocytes.
Title: IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin.

The following PTGIR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PTGIR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02719	NM_000960.4 Latest version!	Homo sapiens prostaglandin I2 receptor (PTGIR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu52380	XM_005259093.3 Latest version!	Homo sapiens prostaglandin I2 receptor (PTGIR), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu52381	XM_005259095.4 Latest version!	Homo sapiens prostaglandin I2 receptor (PTGIR), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu02719	NM_000960.3	Homo sapiens prostaglandin I2 receptor (PTGIR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu52380	XM_005259093.2	Homo sapiens prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu52381	XM_005259095.3	Homo sapiens prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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Reference Sequences (Refseq)

PTGIR ( NM_000960.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000951.1 Homo sapiens prostaglandin I2 receptor (PTGIR), mRNA.

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CloneID	OHu02719
Clone ID Related Accession (Same CDS sequence)	NM_000960.4 , NM_000960.3
Accession Version	NM_000960.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-07
Organism	Homo sapiens(human)
Product	prostacyclin receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA652875.1, D25418.1 and BQ185457.1. On Nov 22, 2018 this sequence version replaced NM_000960.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC110342.1, BC075814.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153307, SAMEA2155751 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000291294.7/ ENSP00000291294.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGAT CCGCTGCTTC 
ACCCAGGCTG TCGCCCCTGA CAGCAGCAGT GAGATGGGGG ACCTCCTTGC CTTCCGCTTC 
TACGCCTTCA ACCCCATCCT GGACCCCTGG GTCTTCATCC TTTTCCGCAA GGCTGTCTTC 
CAGCGACTCA AGCTCTGGGT CTGCTGCCTG TGCCTCGGGC CTGCCCACGG AGACTCGCAG 
ACACCCCTTT CCCAGCTCGC CTCAGGGAGG AGGGACCCAA GGGCCCCCTC TGCTCCTGTG 
GGAAAGGAGG GGAGCTGCGT GCCTTTGTCG GCTTGGGGCG AGGGGCAGGT GGAGCCCTTG 
CCTCCCACAC AGCAGTCCAG CGGCAGCGCC GTGGGAACGT CGTCCAAAGC AGAAGCCAGC 
GTCGCCTGCT CCCTCTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000951.1
CDS	106..1266
Translation	MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC

Target ORF information:

RefSeq Version	NM_000960.4
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin I2 receptor (PTGIR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000960.4

ORF Insert Sequence:

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGAT CCGCTGCTTC 
ACCCAGGCTG TCGCCCCTGA CAGCAGCAGT GAGATGGGGG ACCTCCTTGC CTTCCGCTTC 
TACGCCTTCA ACCCCATCCT GGACCCCTGG GTCTTCATCC TTTTCCGCAA GGCTGTCTTC 
CAGCGACTCA AGCTCTGGGT CTGCTGCCTG TGCCTCGGGC CTGCCCACGG AGACTCGCAG 
ACACCCCTTT CCCAGCTCGC CTCAGGGAGG AGGGACCCAA GGGCCCCCTC TGCTCCTGTG 
GGAAAGGAGG GGAGCTGCGT GCCTTTGTCG GCTTGGGGCG AGGGGCAGGT GGAGCCCTTG 
CCTCCCACAC AGCAGTCCAG CGGCAGCGCC GTGGGAACGT CGTCCAAAGC AGAAGCCAGC 
GTCGCCTGCT CCCTCTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGIR ( NM_000960.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000951.1 Homo sapiens prostaglandin I2 receptor (PTGIR), mRNA.

Price & Availability↑

CloneID	OHu02719
Clone ID Related Accession (Same CDS sequence)	NM_000960.4 , NM_000960.3
Accession Version	NM_000960.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	prostacyclin receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA652875.1, D25418.1 and BQ185457.1. On Dec 17, 2003 this sequence version replaced NM_000960.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC110342.1, BC075814.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153307, SAMEA2155751 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGAT CCGCTGCTTC 
ACCCAGGCTG TCGCCCCTGA CAGCAGCAGT GAGATGGGGG ACCTCCTTGC CTTCCGCTTC 
TACGCCTTCA ACCCCATCCT GGACCCCTGG GTCTTCATCC TTTTCCGCAA GGCTGTCTTC 
CAGCGACTCA AGCTCTGGGT CTGCTGCCTG TGCCTCGGGC CTGCCCACGG AGACTCGCAG 
ACACCCCTTT CCCAGCTCGC CTCAGGGAGG AGGGACCCAA GGGCCCCCTC TGCTCCTGTG 
GGAAAGGAGG GGAGCTGCGT GCCTTTGTCG GCTTGGGGCG AGGGGCAGGT GGAGCCCTTG 
CCTCCCACAC AGCAGTCCAG CGGCAGCGCC GTGGGAACGT CGTCCAAAGC AGAAGCCAGC 
GTCGCCTGCT CCCTCTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000951.1
CDS	114..1274
Translation	MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC

Target ORF information:

RefSeq Version	NM_000960.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin I2 receptor (PTGIR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000960.3

ORF Insert Sequence:

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGAT CCGCTGCTTC 
ACCCAGGCTG TCGCCCCTGA CAGCAGCAGT GAGATGGGGG ACCTCCTTGC CTTCCGCTTC 
TACGCCTTCA ACCCCATCCT GGACCCCTGG GTCTTCATCC TTTTCCGCAA GGCTGTCTTC 
CAGCGACTCA AGCTCTGGGT CTGCTGCCTG TGCCTCGGGC CTGCCCACGG AGACTCGCAG 
ACACCCCTTT CCCAGCTCGC CTCAGGGAGG AGGGACCCAA GGGCCCCCTC TGCTCCTGTG 
GGAAAGGAGG GGAGCTGCGT GCCTTTGTCG GCTTGGGGCG AGGGGCAGGT GGAGCCCTTG 
CCTCCCACAC AGCAGTCCAG CGGCAGCGCC GTGGGAACGT CGTCCAAAGC AGAAGCCAGC 
GTCGCCTGCT CCCTCTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGIR ( XM_005259093.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005259150.1 Homo sapiens prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu52380
Clone ID Related Accession (Same CDS sequence)	XM_005259093.2 , XM_005259093.3
Accession Version	XM_005259093.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	prostacyclin receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 3, 2014 this sequence version replaced XM_005259093.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGAT GAGGGGCAGT 
GTCTTTCGCC CAGTCACACA GAGCCAGGTC CTGGTCCTGG GTCCTTCCAT TGTAGAGCCT 
GATCTCCCAC CTACCTGGCT CCCCTCTGCC TCAGAGCAGG CCCCACCCTT GCCTCTGCAC 
CTCGGTTTCC TGCGGGGACC CCGTCCTGCC CCTCCCCAAT GGGAGTGGCA CAGACCCTGG 
TACCCACTCA GTGTCTGTGA CACCTGGTCG TGCCACCTTT CTTCTGAGCT TCAGTTTCTG 
TTTCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005259150.1
CDS	135..1163
Translation	MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTMRGSVFRPVTQSQVLVLGPSIVEPDLPPTWLPSASEQAPPLPLHLGFLRGPRPAPPQWEWHRPWYPLSVCDTWSCHLSSELQFLFL

Target ORF information:

RefSeq Version	XM_005259093.2
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005259093.2

ORF Insert Sequence:

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGAT GAGGGGCAGT 
GTCTTTCGCC CAGTCACACA GAGCCAGGTC CTGGTCCTGG GTCCTTCCAT TGTAGAGCCT 
GATCTCCCAC CTACCTGGCT CCCCTCTGCC TCAGAGCAGG CCCCACCCTT GCCTCTGCAC 
CTCGGTTTCC TGCGGGGACC CCGTCCTGCC CCTCCCCAAT GGGAGTGGCA CAGACCCTGG 
TACCCACTCA GTGTCTGTGA CACCTGGTCG TGCCACCTTT CTTCTGAGCT TCAGTTTCTG 
TTTCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGIR ( XM_005259093.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005259150.1 Homo sapiens prostaglandin I2 receptor (PTGIR), transcript variant X1, mRNA.

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CloneID	OHu52380
Clone ID Related Accession (Same CDS sequence)	XM_005259093.2 , XM_005259093.3
Accession Version	XM_005259093.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	prostacyclin receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005259093.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGAT GAGGGGCAGT 
GTCTTTCGCC CAGTCACACA GAGCCAGGTC CTGGTCCTGG GTCCTTCCAT TGTAGAGCCT 
GATCTCCCAC CTACCTGGCT CCCCTCTGCC TCAGAGCAGG CCCCACCCTT GCCTCTGCAC 
CTCGGTTTCC TGCGGGGACC CCGTCCTGCC CCTCCCCAAT GGGAGTGGCA CAGACCCTGG 
TACCCACTCA GTGTCTGTGA CACCTGGTCG TGCCACCTTT CTTCTGAGCT TCAGTTTCTG 
TTTCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005259150.1
CDS	114..1142
Translation	MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTMRGSVFRPVTQSQVLVLGPSIVEPDLPPTWLPSASEQAPPLPLHLGFLRGPRPAPPQWEWHRPWYPLSVCDTWSCHLSSELQFLFL

Target ORF information:

RefSeq Version	XM_005259093.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin I2 receptor (PTGIR), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005259093.3

ORF Insert Sequence:

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGAT GAGGGGCAGT 
GTCTTTCGCC CAGTCACACA GAGCCAGGTC CTGGTCCTGG GTCCTTCCAT TGTAGAGCCT 
GATCTCCCAC CTACCTGGCT CCCCTCTGCC TCAGAGCAGG CCCCACCCTT GCCTCTGCAC 
CTCGGTTTCC TGCGGGGACC CCGTCCTGCC CCTCCCCAAT GGGAGTGGCA CAGACCCTGG 
TACCCACTCA GTGTCTGTGA CACCTGGTCG TGCCACCTTT CTTCTGAGCT TCAGTTTCTG 
TTTCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGIR ( XM_005259095.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005259152.1 Homo sapiens prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu52381
Clone ID Related Accession (Same CDS sequence)	XM_005259095.3 , XM_005259095.4
Accession Version	XM_005259095.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	prostacyclin receptor isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005259095.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005259152.1
CDS	135..908
Translation	MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTQ

Target ORF information:

RefSeq Version	XM_005259095.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005259095.3

ORF Insert Sequence:

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGIR ( XM_005259095.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005259152.1 Homo sapiens prostaglandin I2 receptor (PTGIR), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu52381
Clone ID Related Accession (Same CDS sequence)	XM_005259095.3 , XM_005259095.4
Accession Version	XM_005259095.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	prostacyclin receptor isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005259095.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005259152.1
CDS	114..887
Translation	MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTQ

Target ORF information:

RefSeq Version	XM_005259095.4
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin I2 receptor (PTGIR), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005259095.4

ORF Insert Sequence:

ATGGCGGATT CGTGCAGGAA CCTCACCTAC GTGCGGGGCT CGGTGGGGCC GGCCACCAGC 
ACCCTGATGT TCGTGGCCGG TGTGGTGGGC AACGGGCTGG CCCTGGGCAT CCTGAGCGCA 
CGGCGACCGG CGCGCCCCTC GGCCTTCGCG GTGCTGGTGA CCGGACTGGC GGCCACCGAC 
CTGCTGGGCA CCAGCTTCCT GAGCCCGGCC GTGTTCGTGG CCTATGCGCG CAACAGCTCC 
CTGCTGGGCC TGGCCCGAGG CGGCCCCGCC CTGTGCGATG CCTTCGCCTT CGCCATGACC 
TTCTTCGGCC TGGCGTCCAT GCTCATCCTC TTTGCCATGG CCGTGGAGCG CTGCCTGGCG 
CTGAGCCACC CCTACCTCTA CGCGCAGCTG GACGGGCCCC GCTGCGCCCG CCTGGCGCTG 
CCAGCCATCT ACGCCTTCTG CGTCCTCTTC TGCGCGCTGC CCCTGCTGGG CCTGGGCCAA 
CACCAGCAGT ACTGCCCCGG CAGCTGGTGC TTCCTCCGCA TGCGCTGGGC CCAGCCGGGC 
GGCGCCGCCT TCTCGCTGGC CTACGCCGGC CTGGTGGCCC TGCTGGTGGC TGCCATCTTC 
CTCTGCAACG GCTCGGTCAC CCTCAGCCTC TGCCGCATGT ACCGCCAGCA GAAGCGCCAC 
CAGGGCTCTC TGGGTCCACG GCCGCGCACC GGAGAGGACG AGGTGGACCA CCTGATCCTG 
CTGGCCCTCA TGACAGTGGT CATGGCCGTG TGCTCCCTGC CTCTCACGCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of ?-helix 4 (?4) of Rab11a as a novel Rab11-binding domain (RBD): Interaction of Rab11a with the Prostacyclin Receptor.
Biochimica et biophysica acta1864(10)1819-1832(2017 10)
Mulvaney EP,O'Meara F,Khan AR,O'Connell DJ,Kinsella BT

Role of prostacyclin signaling in endothelial production of soluble amyloid precursor protein-? in cerebral microvessels.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism37(1)106-122(2017 Jan)
He T,Santhanam AV,Lu T,d'Uscio LV,Katusic ZS

Regulated expression of the prostacyclin receptor (IP) gene by androgens within the vasculature: Combined role for androgens and serum cholesterol.
Biochimica et biophysica acta1859(10)1333-51(2016 10)
Eivers SB,Kinsella BT

Prostaglandin I2 Receptor Agonism Preserves ?-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms.
Diabetes65(5)1398-409(2016 05)
Batchu SN,Majumder S,Bowskill BB,White KE,Advani SL,Brijmohan AS,Liu Y,Thai K,Azizi PM,Lee WL,Advani A

IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin.
Biochimica et biophysica acta1861(4)285-93(2016 Apr)
Ghandour RA,Giroud M,Vegiopoulos A,Herzig S,Ailhaud G,Amri EZ,Pisani DF

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PTGIR cDNA ORF clone, Homo sapiens(human)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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