Gene Symbol | RPA3 |
Entrez Gene ID | 6119 |
Full Name | replication protein A3 |
Synonyms | REPA3,RP-A p14 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » RPA3 cDNA ORF clone
Gene Symbol | RPA3 |
Entrez Gene ID | 6119 |
Full Name | replication protein A3 |
Synonyms | REPA3,RP-A p14 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_002947.4 | NP_002938.1 | replication protein A 14 kDa subunit |
NM_002947.3 | NP_002938.1 | replication protein A 14 kDa subunit |
NM_002947.5 | NP_002938.1 | replication protein A 14 kDa subunit |
Homo sapiens (human) | RPA3 | NP_002938.1 |
Bos taurus (cattle) | RPA3 | NP_001029599.1 |
Rattus norvegicus (Norway rat) | LOC100362927 | XP_002728026.1 |
Gallus gallus (chicken) | RPA3 | XP_418679.1 |
Pan troglodytes (chimpanzee) | RPA3 | XP_527665.2 |
RPA3 | XP_001086880.1 | |
Canis lupus familiaris (dog) | RPA3 | XP_538570.2 |
Mus musculus (house mouse) | Rpa3 | NP_080908.1 |
Rattus norvegicus (Norway rat) | Rpa3 | NP_001100054.1 |
Danio rerio (zebrafish) | rpa3 | NP_956521.1 |
Xenopus tropicalis (tropical clawed frog) | rpa3 | NP_001016626.1 |
Replication Protein A 3 Is Associated with Hepatocellular Carcinoma Tumorigenesis and Poor Patient Survival.
Xiao W, Zheng J, Zhou B, Pan L
Digestive diseases (Basel, Switzerland)36(1)26-32(2018)
RPA3 is a potential marker of prognosis and radioresistance for nasopharyngeal carcinoma.
Qu C, Zhao Y, Feng G, Chen C, Tao Y, Zhou S, Liu S, Chang H, Zeng M, Xia Y
Journal of cellular and molecular medicine21(11)2872-2883(2017 Nov)
Elevated Expression of RPA3 Is Involved in Gastric Cancer Tumorigenesis and Associated with Poor Patient Survival.
Dai Z, Wang S, Zhang W, Yang Y
Digestive diseases and sciences62(9)2369-2375(2017 09)
RPA Interacts with HIRA and Regulates H3.3 Deposition at Gene Regulatory Elements in Mammalian Cells.
Zhang H, Gan H, Wang Z, Lee JH, Zhou H, Ordog T, Wold MS, Ljungman M, Zhang Z
Molecular cell65(2)272-284(2017 Jan)
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Up-regulation of RPA3 is involved in gastric cancer tumorigenesis and is associated with poorer patient survival.
Title: Elevated Expression of RPA3 Is Involved in Gastric Cancer Tumorigenesis and Associated with Poor Patient Survival.
RPA, best known for its role in DNA replication and repair, recruits HIRA to promoters and enhancers and regulates deposition of newly synthesized H3.3 to these regulatory elements for gene regulation.
Title: RPA Interacts with HIRA and Regulates H3.3 Deposition at Gene Regulatory Elements in Mammalian Cells.
The allele "T" of rs6947203 in the RPA3 gene acts as a protective allele in glioma.
Title: TP53 and RPA3 gene variations were associated with risk of glioma in a Chinese Han population.
Data indicate taht candidate genes ACTB, BZW, OCM, MACC1, NXPH1, PRPS1L1, RAC1 and RPA3, which lie within the DFNB90 region, were sequenced and no potentially causal variants were identified.
Title: Novel autosomal recessive nonsyndromic hearing impairment locus DFNB90 maps to 7p22.1-p15.3.
Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: XPC genetic polymorphisms correlate with the response to imatinib treatment in patients with chronic phase chronic myeloid leukemia.
The following RPA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu04023 | |
Clone ID Related Accession (Same CDS sequence) | NM_002947.4 , NM_002947.3 , NM_002947.5 | |
Accession Version | NM_002947.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-24 | |
Organism | Homo sapiens(human) | |
Product | replication protein A 14 kDa subunit | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC009868.2, AC004948.2 and AI243725.1. On Dec 16, 2015 this sequence version replaced NM_002947.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC009868.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA2142348 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGTGGACA TGATGGACTT GCCCAGGTCG CGCATCAACG CCGGCATGCT AGCTCAATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_002938.1 |
CDS | 1173..1538 |
Translation |
Target ORF information:
Target ORF information:
|
NM_002947.4 |
1 | ATGGTGGACA TGATGGACTT GCCCAGGTCG CGCATCAACG CCGGCATGCT AGCTCAATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu04023 | |
Clone ID Related Accession (Same CDS sequence) | NM_002947.4 , NM_002947.3 , NM_002947.5 | |
Accession Version | NM_002947.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-14 | |
Organism | Homo sapiens(Human) | |
Product | replication protein A 14 kDa subunit | |
Comment |
1 | ATGGTGGACA TGATGGACTT GCCCAGGTCG CGCATCAACG CCGGCATGCT AGCTCAATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_002938.1 |
Translation |
Target ORF information:
Target ORF information:
|
NM_002947.3 |
1 | ATGGTGGACA TGATGGACTT GCCCAGGTCG CGCATCAACG CCGGCATGCT AGCTCAATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu04023 | |
Clone ID Related Accession (Same CDS sequence) | NM_002947.4 , NM_002947.3 , NM_002947.5 | |
Accession Version | NM_002947.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-29 | |
Organism | Homo sapiens(human) | |
Product | replication protein A 14 kDa subunit | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC009868.2, AC004948.2 and AI243725.1. On May 17, 2019 this sequence version replaced NM_002947.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC009868.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA2142348 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000223129.8/ ENSP00000223129.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## |
1 | ATGGTGGACA TGATGGACTT GCCCAGGTCG CGCATCAACG CCGGCATGCT AGCTCAATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_002938.1 |
CDS | 1173..1538 |
Translation |
Target ORF information:
Target ORF information:
|
NM_002947.5 |
1 | ATGGTGGACA TGATGGACTT GCCCAGGTCG CGCATCAACG CCGGCATGCT AGCTCAATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Replication Protein A 3 Is Associated with Hepatocellular Carcinoma Tumorigenesis and Poor Patient Survival. |
RPA3 is a potential marker of prognosis and radioresistance for nasopharyngeal carcinoma. |
Elevated Expression of RPA3 Is Involved in Gastric Cancer Tumorigenesis and Associated with Poor Patient Survival. |
RPA Interacts with HIRA and Regulates H3.3 Deposition at Gene Regulatory Elements in Mammalian Cells. |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. |