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SCNN1B cDNA ORF clone, Homo sapiens (human)

Gene Symbol SCNN1B
Entrez Gene ID 6338
Full Name sodium channel, non voltage gated 1 beta subunit
Synonyms BESC1, ENaCb, ENaCbeta, SCNEB
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p12.2-p12.1

Summary Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009]. lac of sum
Disorder MIM:

600760

Disorder Html: Liddle syndrome, 177200 (3); Pseudohypoaldosteronism, type I, 264350

mRNA and Protein(s)

mRNA Protein Name
XM_011545913 XP_011544215 amiloride-sensitive sodium channel subunit beta isoform X1
XM_011545914 XP_011544216 amiloride-sensitive sodium channel subunit beta isoform X2
NM_000336 NP_000327 amiloride-sensitive sodium channel subunit beta



Homo sapiens (human) SCNN1B NP_000327.2
Pan troglodytes (chimpanzee) SCNN1B XP_001161438.2
Macaca mulatta (Rhesus monkey) SCNN1B XP_001093933.1
Canis lupus familiaris (dog) SCNN1B XP_005621478.1
Bos taurus (cattle) SCNN1B NP_001091544.1
Mus musculus (house mouse) Scnn1b NP_035455.1
Rattus norvegicus (Norway rat) Scnn1b NP_036780.1
Gallus gallus (chicken) SCNN1B XP_425247.3
Xenopus (Silurana) tropicalis (western clawed frog) scnn1b NP_001072437.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SCNN1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SCNN1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu60387 XM_011545913 PREDICTED: Homo sapiens sodium channel, non voltage gated 1 beta subunit (SCNN1B), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu60388 XM_011545914 PREDICTED: Homo sapiens sodium channel, non voltage gated 1 beta subunit (SCNN1B), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu18452
NM_000336 Homo sapiens sodium channel, non voltage gated 1 beta subunit (SCNN1B), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu60387
Clone ID Related Accession (Same CDS sequence) XM_011545913
Accession Version XM_011545913.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1956bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product amiloride-sensitive sodium channel subunit beta isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_187260.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
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721
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961
1021
1081
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1321
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1501
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ATGGGGAAAC CAGGGCACAG AGAGGGTGCC ACTATGCACG TGAAGAAGTA CCTGCTGAAG 
GGCCTGCATC GGCTGCAGAA GGGCCCCGGC TACACGTACA AGGAGCTGCT GGTGTGGTAC
TGCGACAACA CCAACACCCA CGGCCCCAAG CGCATCATCT GTGAGGGGCC CAAGAAGAAA
GCCATGTGGT TCCTGCTCAC CCTGCTCTTC GCCGCCCTCG TCTGCTGGCA GTGGGGCATC
TTCATCAGGA CCTACTTGAG CTGGGAGGTC AGCGTCTCCC TCTCCGTAGG CTTCAAGACC
ATGGACTTCC CTGCCGTCAC CATCTGCAAT GCTAGCCCCT TCAAGTATTC CAAAATCAAG
CATTTGCTGA AGGACCTGGA TGAGCTGATG GAAGCTGTCC TGGAGAGAAT CCTGGCTCCT
GAGCTAAGCC ATGCCAATGC CACCAGGAAC CTGAACTTCT CCATCTGGAA CCACACACCC
CTGGTCCTTA TTGATGAACG GAACCCCCAC CACCCCATGG TCCTTGATCT CTTTGGAGAC
AACCACAATG GCTTAACAAG CAGCTCAGCA TCAGAAAAGA TCTGTAATGC CCACGGGTGC
AAAATGGCCA TGAGACTATG TAGCCTCAAC AGGACCCAGT GTACCTTCCG GAACTTCACC
AGTGCTACCC AGGCATTGAC AGAGTGGTAC ATCCTGCAGG CCACCAACAT CTTTGCACAG
GTGCCACAGC AGGAGCTAGT AGAGATGAGC TACCCCGGCG AGCAGATGAT CCTGGCCTGC
CTATTCGGAG CTGAGCCCTG CAACTACCGG AACTTCACGT CCATCTTCTA CCCTCACTAT
GGCAACTGTT ACATCTTCAA CTGGGGCATG ACAGAGAAGG CACTTCCTTC GGCCAACCCT
GGAACTGAAT TCGGCCTGAA GTTGATCCTG GACATAGGCC AGGAAGACTA CGTCCCCTTC
CTTGCGTCCA CGGCCGGGGT CAGGCTGATG CTTCACGAGC AGAGGTCATA CCCCTTCATC
AGAGATGAGG GCATCTACGC CATGTCGGGG ACAGAGACGT CCATCGGGGT ACTCGTGGAC
AAGCTTCAGC GCATGGGGGA GCCCTACAGC CCGTGCACCG TGAATGGTTC TGAGGTCCCC
GTCCAAAACT TCTACAGTGA CTACAACACG ACCTACTCCA TCCAGGCCTG TCTTCGCTCC
TGCTTCCAAG ACCACATGAT CCGTAACTGC AACTGTGGCC ACTACCTGTA CCCACTGCCC
CGTGGGGAGA AATACTGCAA CAACCGGGAC TTCCCAGACT GGGCCCATTG CTACTCAGAT
CTACAGATGA GCGTGGCGCA GAGAGAGACC TGCATTGGCA TGTGCAAGGA GTCCTGCAAT
GACACCCAGT ACAAGATGAC CATCTCCATG GCTGACTGGC CTTCTGAGGC CTCCGAGGAC
TGGATTTTCC ACGTCTTGTC TCAGGAGCGG GACCAAAGCA CCAATATCAC CCTGAGCAGG
AAGGGAATTG TCAAGCTCAA CATCTACTTC CAAGAATTTA ACTATCGCAC CATTGAAGAA
TCAGCAGCCA ATAACATCGT CTGGCTGCTC TCGAATCTGG GTGGCCAGTT TGGCTTCTGG
ATGGGGGGCT CTGTGCTGTG CCTCATCGAG TTTGGGGAGA TCATCATCGA CTTTGTGTGG
ATCACCATCA TCAAGCTGGT GGCCTTGGCC AAGAGCCTAC GGCAGCGGCG AGCCCAAGCC
AGCTACGCTG GCCCACCGCC CACCGTGGCC GAGCTGGTGG AGGCCCACAC CAACTTTGGC
TTCCAGCCTG ACACGGCCCC CCGCAGCCCC AACACTGGGC CCTACCCCAG TGAGCAGGCC
CTGCCCATCC CAGGCACCCC GCCCCCCAAC TATGACTCCC TGCGTCTGCA GCCGCTGGAC
GTCATCGAGT CTGACAGTGA GGGTGATGCC ATCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011544215.1
CDS139..2094
Misc Feature(1)232..2040(+)
Misc Feature(2)256..1791(+)
Translation

Target ORF information:

RefSeq Version XM_011545913
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens sodium channel, non voltage gated 1 beta subunit (SCNN1B), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011545913

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
ATGGGGAAAC CAGGGCACAG AGAGGGTGCC ACTATGCACG TGAAGAAGTA CCTGCTGAAG 
GGCCTGCATC GGCTGCAGAA GGGCCCCGGC TACACGTACA AGGAGCTGCT GGTGTGGTAC
TGCGACAACA CCAACACCCA CGGCCCCAAG CGCATCATCT GTGAGGGGCC CAAGAAGAAA
GCCATGTGGT TCCTGCTCAC CCTGCTCTTC GCCGCCCTCG TCTGCTGGCA GTGGGGCATC
TTCATCAGGA CCTACTTGAG CTGGGAGGTC AGCGTCTCCC TCTCCGTAGG CTTCAAGACC
ATGGACTTCC CTGCCGTCAC CATCTGCAAT GCTAGCCCCT TCAAGTATTC CAAAATCAAG
CATTTGCTGA AGGACCTGGA TGAGCTGATG GAAGCTGTCC TGGAGAGAAT CCTGGCTCCT
GAGCTAAGCC ATGCCAATGC CACCAGGAAC CTGAACTTCT CCATCTGGAA CCACACACCC
CTGGTCCTTA TTGATGAACG GAACCCCCAC CACCCCATGG TCCTTGATCT CTTTGGAGAC
AACCACAATG GCTTAACAAG CAGCTCAGCA TCAGAAAAGA TCTGTAATGC CCACGGGTGC
AAAATGGCCA TGAGACTATG TAGCCTCAAC AGGACCCAGT GTACCTTCCG GAACTTCACC
AGTGCTACCC AGGCATTGAC AGAGTGGTAC ATCCTGCAGG CCACCAACAT CTTTGCACAG
GTGCCACAGC AGGAGCTAGT AGAGATGAGC TACCCCGGCG AGCAGATGAT CCTGGCCTGC
CTATTCGGAG CTGAGCCCTG CAACTACCGG AACTTCACGT CCATCTTCTA CCCTCACTAT
GGCAACTGTT ACATCTTCAA CTGGGGCATG ACAGAGAAGG CACTTCCTTC GGCCAACCCT
GGAACTGAAT TCGGCCTGAA GTTGATCCTG GACATAGGCC AGGAAGACTA CGTCCCCTTC
CTTGCGTCCA CGGCCGGGGT CAGGCTGATG CTTCACGAGC AGAGGTCATA CCCCTTCATC
AGAGATGAGG GCATCTACGC CATGTCGGGG ACAGAGACGT CCATCGGGGT ACTCGTGGAC
AAGCTTCAGC GCATGGGGGA GCCCTACAGC CCGTGCACCG TGAATGGTTC TGAGGTCCCC
GTCCAAAACT TCTACAGTGA CTACAACACG ACCTACTCCA TCCAGGCCTG TCTTCGCTCC
TGCTTCCAAG ACCACATGAT CCGTAACTGC AACTGTGGCC ACTACCTGTA CCCACTGCCC
CGTGGGGAGA AATACTGCAA CAACCGGGAC TTCCCAGACT GGGCCCATTG CTACTCAGAT
CTACAGATGA GCGTGGCGCA GAGAGAGACC TGCATTGGCA TGTGCAAGGA GTCCTGCAAT
GACACCCAGT ACAAGATGAC CATCTCCATG GCTGACTGGC CTTCTGAGGC CTCCGAGGAC
TGGATTTTCC ACGTCTTGTC TCAGGAGCGG GACCAAAGCA CCAATATCAC CCTGAGCAGG
AAGGGAATTG TCAAGCTCAA CATCTACTTC CAAGAATTTA ACTATCGCAC CATTGAAGAA
TCAGCAGCCA ATAACATCGT CTGGCTGCTC TCGAATCTGG GTGGCCAGTT TGGCTTCTGG
ATGGGGGGCT CTGTGCTGTG CCTCATCGAG TTTGGGGAGA TCATCATCGA CTTTGTGTGG
ATCACCATCA TCAAGCTGGT GGCCTTGGCC AAGAGCCTAC GGCAGCGGCG AGCCCAAGCC
AGCTACGCTG GCCCACCGCC CACCGTGGCC GAGCTGGTGG AGGCCCACAC CAACTTTGGC
TTCCAGCCTG ACACGGCCCC CCGCAGCCCC AACACTGGGC CCTACCCCAG TGAGCAGGCC
CTGCCCATCC CAGGCACCCC GCCCCCCAAC TATGACTCCC TGCGTCTGCA GCCGCTGGAC
GTCATCGAGT CTGACAGTGA GGGTGATGCC ATCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60388
Clone ID Related Accession (Same CDS sequence) XM_011545914
Accession Version XM_011545914.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1941bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product amiloride-sensitive sodium channel subunit beta isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_187260.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
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ATGACTGTGG GTGCCACTAT GCACGTGAAG AAGTACCTGC TGAAGGGCCT GCATCGGCTG 
CAGAAGGGCC CCGGCTACAC GTACAAGGAG CTGCTGGTGT GGTACTGCGA CAACACCAAC
ACCCACGGCC CCAAGCGCAT CATCTGTGAG GGGCCCAAGA AGAAAGCCAT GTGGTTCCTG
CTCACCCTGC TCTTCGCCGC CCTCGTCTGC TGGCAGTGGG GCATCTTCAT CAGGACCTAC
TTGAGCTGGG AGGTCAGCGT CTCCCTCTCC GTAGGCTTCA AGACCATGGA CTTCCCTGCC
GTCACCATCT GCAATGCTAG CCCCTTCAAG TATTCCAAAA TCAAGCATTT GCTGAAGGAC
CTGGATGAGC TGATGGAAGC TGTCCTGGAG AGAATCCTGG CTCCTGAGCT AAGCCATGCC
AATGCCACCA GGAACCTGAA CTTCTCCATC TGGAACCACA CACCCCTGGT CCTTATTGAT
GAACGGAACC CCCACCACCC CATGGTCCTT GATCTCTTTG GAGACAACCA CAATGGCTTA
ACAAGCAGCT CAGCATCAGA AAAGATCTGT AATGCCCACG GGTGCAAAAT GGCCATGAGA
CTATGTAGCC TCAACAGGAC CCAGTGTACC TTCCGGAACT TCACCAGTGC TACCCAGGCA
TTGACAGAGT GGTACATCCT GCAGGCCACC AACATCTTTG CACAGGTGCC ACAGCAGGAG
CTAGTAGAGA TGAGCTACCC CGGCGAGCAG ATGATCCTGG CCTGCCTATT CGGAGCTGAG
CCCTGCAACT ACCGGAACTT CACGTCCATC TTCTACCCTC ACTATGGCAA CTGTTACATC
TTCAACTGGG GCATGACAGA GAAGGCACTT CCTTCGGCCA ACCCTGGAAC TGAATTCGGC
CTGAAGTTGA TCCTGGACAT AGGCCAGGAA GACTACGTCC CCTTCCTTGC GTCCACGGCC
GGGGTCAGGC TGATGCTTCA CGAGCAGAGG TCATACCCCT TCATCAGAGA TGAGGGCATC
TACGCCATGT CGGGGACAGA GACGTCCATC GGGGTACTCG TGGACAAGCT TCAGCGCATG
GGGGAGCCCT ACAGCCCGTG CACCGTGAAT GGTTCTGAGG TCCCCGTCCA AAACTTCTAC
AGTGACTACA ACACGACCTA CTCCATCCAG GCCTGTCTTC GCTCCTGCTT CCAAGACCAC
ATGATCCGTA ACTGCAACTG TGGCCACTAC CTGTACCCAC TGCCCCGTGG GGAGAAATAC
TGCAACAACC GGGACTTCCC AGACTGGGCC CATTGCTACT CAGATCTACA GATGAGCGTG
GCGCAGAGAG AGACCTGCAT TGGCATGTGC AAGGAGTCCT GCAATGACAC CCAGTACAAG
ATGACCATCT CCATGGCTGA CTGGCCTTCT GAGGCCTCCG AGGACTGGAT TTTCCACGTC
TTGTCTCAGG AGCGGGACCA AAGCACCAAT ATCACCCTGA GCAGGAAGGG AATTGTCAAG
CTCAACATCT ACTTCCAAGA ATTTAACTAT CGCACCATTG AAGAATCAGC AGCCAATAAC
ATCGTCTGGC TGCTCTCGAA TCTGGGTGGC CAGTTTGGCT TCTGGATGGG GGGCTCTGTG
CTGTGCCTCA TCGAGTTTGG GGAGATCATC ATCGACTTTG TGTGGATCAC CATCATCAAG
CTGGTGGCCT TGGCCAAGAG CCTACGGCAG CGGCGAGCCC AAGCCAGCTA CGCTGGCCCA
CCGCCCACCG TGGCCGAGCT GGTGGAGGCC CACACCAACT TTGGCTTCCA GCCTGACACG
GCCCCCCGCA GCCCCAACAC TGGGCCCTAC CCCAGTGAGC AGGCCCTGCC CATCCCAGGC
ACCCCGCCCC CCAACTATGA CTCCCTGCGT CTGCAGCCGC TGGACGTCAT CGAGTCTGAC
AGTGAGGGTG ATGCCATCTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011544216.1
CDS7..1947
Misc Feature(1)85..1893(+)
Misc Feature(2)109..1644(+)
Translation

Target ORF information:

RefSeq Version XM_011545914
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens sodium channel, non voltage gated 1 beta subunit (SCNN1B), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011545914

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
ATGACTGTGG GTGCCACTAT GCACGTGAAG AAGTACCTGC TGAAGGGCCT GCATCGGCTG 
CAGAAGGGCC CCGGCTACAC GTACAAGGAG CTGCTGGTGT GGTACTGCGA CAACACCAAC
ACCCACGGCC CCAAGCGCAT CATCTGTGAG GGGCCCAAGA AGAAAGCCAT GTGGTTCCTG
CTCACCCTGC TCTTCGCCGC CCTCGTCTGC TGGCAGTGGG GCATCTTCAT CAGGACCTAC
TTGAGCTGGG AGGTCAGCGT CTCCCTCTCC GTAGGCTTCA AGACCATGGA CTTCCCTGCC
GTCACCATCT GCAATGCTAG CCCCTTCAAG TATTCCAAAA TCAAGCATTT GCTGAAGGAC
CTGGATGAGC TGATGGAAGC TGTCCTGGAG AGAATCCTGG CTCCTGAGCT AAGCCATGCC
AATGCCACCA GGAACCTGAA CTTCTCCATC TGGAACCACA CACCCCTGGT CCTTATTGAT
GAACGGAACC CCCACCACCC CATGGTCCTT GATCTCTTTG GAGACAACCA CAATGGCTTA
ACAAGCAGCT CAGCATCAGA AAAGATCTGT AATGCCCACG GGTGCAAAAT GGCCATGAGA
CTATGTAGCC TCAACAGGAC CCAGTGTACC TTCCGGAACT TCACCAGTGC TACCCAGGCA
TTGACAGAGT GGTACATCCT GCAGGCCACC AACATCTTTG CACAGGTGCC ACAGCAGGAG
CTAGTAGAGA TGAGCTACCC CGGCGAGCAG ATGATCCTGG CCTGCCTATT CGGAGCTGAG
CCCTGCAACT ACCGGAACTT CACGTCCATC TTCTACCCTC ACTATGGCAA CTGTTACATC
TTCAACTGGG GCATGACAGA GAAGGCACTT CCTTCGGCCA ACCCTGGAAC TGAATTCGGC
CTGAAGTTGA TCCTGGACAT AGGCCAGGAA GACTACGTCC CCTTCCTTGC GTCCACGGCC
GGGGTCAGGC TGATGCTTCA CGAGCAGAGG TCATACCCCT TCATCAGAGA TGAGGGCATC
TACGCCATGT CGGGGACAGA GACGTCCATC GGGGTACTCG TGGACAAGCT TCAGCGCATG
GGGGAGCCCT ACAGCCCGTG CACCGTGAAT GGTTCTGAGG TCCCCGTCCA AAACTTCTAC
AGTGACTACA ACACGACCTA CTCCATCCAG GCCTGTCTTC GCTCCTGCTT CCAAGACCAC
ATGATCCGTA ACTGCAACTG TGGCCACTAC CTGTACCCAC TGCCCCGTGG GGAGAAATAC
TGCAACAACC GGGACTTCCC AGACTGGGCC CATTGCTACT CAGATCTACA GATGAGCGTG
GCGCAGAGAG AGACCTGCAT TGGCATGTGC AAGGAGTCCT GCAATGACAC CCAGTACAAG
ATGACCATCT CCATGGCTGA CTGGCCTTCT GAGGCCTCCG AGGACTGGAT TTTCCACGTC
TTGTCTCAGG AGCGGGACCA AAGCACCAAT ATCACCCTGA GCAGGAAGGG AATTGTCAAG
CTCAACATCT ACTTCCAAGA ATTTAACTAT CGCACCATTG AAGAATCAGC AGCCAATAAC
ATCGTCTGGC TGCTCTCGAA TCTGGGTGGC CAGTTTGGCT TCTGGATGGG GGGCTCTGTG
CTGTGCCTCA TCGAGTTTGG GGAGATCATC ATCGACTTTG TGTGGATCAC CATCATCAAG
CTGGTGGCCT TGGCCAAGAG CCTACGGCAG CGGCGAGCCC AAGCCAGCTA CGCTGGCCCA
CCGCCCACCG TGGCCGAGCT GGTGGAGGCC CACACCAACT TTGGCTTCCA GCCTGACACG
GCCCCCCGCA GCCCCAACAC TGGGCCCTAC CCCAGTGAGC AGGCCCTGCC CATCCCAGGC
ACCCCGCCCC CCAACTATGA CTCCCTGCGT CTGCAGCCGC TGGACGTCAT CGAGTCTGAC
AGTGAGGGTG ATGCCATCTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18452
Clone ID Related Accession (Same CDS sequence) NM_000336
Accession Version NM_000336.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1923bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product amiloride-sensitive sodium channel subunit beta
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU105979.1, BC036352.1 and L36593.1. This sequence is a reference standard in the RefSeqGene project. On Jan 31, 2007 this sequence version replaced gi:4506816. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036352.1, X87159.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
ATGCACGTGA AGAAGTACCT GCTGAAGGGC CTGCATCGGC TGCAGAAGGG CCCCGGCTAC 
ACGTACAAGG AGCTGCTGGT GTGGTACTGC GACAACACCA ACACCCACGG CCCCAAGCGC
ATCATCTGTG AGGGGCCCAA GAAGAAAGCC ATGTGGTTCC TGCTCACCCT GCTCTTCGCC
GCCCTCGTCT GCTGGCAGTG GGGCATCTTC ATCAGGACCT ACTTGAGCTG GGAGGTCAGC
GTCTCCCTCT CCGTAGGCTT CAAGACCATG GACTTCCCTG CCGTCACCAT CTGCAATGCT
AGCCCCTTCA AGTATTCCAA AATCAAGCAT TTGCTGAAGG ACCTGGATGA GCTGATGGAA
GCTGTCCTGG AGAGAATCCT GGCTCCTGAG CTAAGCCATG CCAATGCCAC CAGGAACCTG
AACTTCTCCA TCTGGAACCA CACACCCCTG GTCCTTATTG ATGAACGGAA CCCCCACCAC
CCCATGGTCC TTGATCTCTT TGGAGACAAC CACAATGGCT TAACAAGCAG CTCAGCATCA
GAAAAGATCT GTAATGCCCA CGGGTGCAAA ATGGCCATGA GACTATGTAG CCTCAACAGG
ACCCAGTGTA CCTTCCGGAA CTTCACCAGT GCTACCCAGG CATTGACAGA GTGGTACATC
CTGCAGGCCA CCAACATCTT TGCACAGGTG CCACAGCAGG AGCTAGTAGA GATGAGCTAC
CCCGGCGAGC AGATGATCCT GGCCTGCCTA TTCGGAGCTG AGCCCTGCAA CTACCGGAAC
TTCACGTCCA TCTTCTACCC TCACTATGGC AACTGTTACA TCTTCAACTG GGGCATGACA
GAGAAGGCAC TTCCTTCGGC CAACCCTGGA ACTGAATTCG GCCTGAAGTT GATCCTGGAC
ATAGGCCAGG AAGACTACGT CCCCTTCCTT GCGTCCACGG CCGGGGTCAG GCTGATGCTT
CACGAGCAGA GGTCATACCC CTTCATCAGA GATGAGGGCA TCTACGCCAT GTCGGGGACA
GAGACGTCCA TCGGGGTACT CGTGGACAAG CTTCAGCGCA TGGGGGAGCC CTACAGCCCG
TGCACCGTGA ATGGTTCTGA GGTCCCCGTC CAAAACTTCT ACAGTGACTA CAACACGACC
TACTCCATCC AGGCCTGTCT TCGCTCCTGC TTCCAAGACC ACATGATCCG TAACTGCAAC
TGTGGCCACT ACCTGTACCC ACTGCCCCGT GGGGAGAAAT ACTGCAACAA CCGGGACTTC
CCAGACTGGG CCCATTGCTA CTCAGATCTA CAGATGAGCG TGGCGCAGAG AGAGACCTGC
ATTGGCATGT GCAAGGAGTC CTGCAATGAC ACCCAGTACA AGATGACCAT CTCCATGGCT
GACTGGCCTT CTGAGGCCTC CGAGGACTGG ATTTTCCACG TCTTGTCTCA GGAGCGGGAC
CAAAGCACCA ATATCACCCT GAGCAGGAAG GGAATTGTCA AGCTCAACAT CTACTTCCAA
GAATTTAACT ATCGCACCAT TGAAGAATCA GCAGCCAATA ACATCGTCTG GCTGCTCTCG
AATCTGGGTG GCCAGTTTGG CTTCTGGATG GGGGGCTCTG TGCTGTGCCT CATCGAGTTT
GGGGAGATCA TCATCGACTT TGTGTGGATC ACCATCATCA AGCTGGTGGC CTTGGCCAAG
AGCCTACGGC AGCGGCGAGC CCAAGCCAGC TACGCTGGCC CACCGCCCAC CGTGGCCGAG
CTGGTGGAGG CCCACACCAA CTTTGGCTTC CAGCCTGACA CGGCCCCCCG CAGCCCCAAC
ACTGGGCCCT ACCCCAGTGA GCAGGCCCTG CCCATCCCAG GCACCCCGCC CCCCAACTAT
GACTCCCTGC GTCTGCAGCC GCTGGACGTC ATCGAGTCTG ACAGTGAGGG TGATGCCATC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000327.2
CDS177..2099
Misc Feature(1)237..2045(+)
Misc Feature(2)261..1796(+)
Misc Feature(3)330..401(+)
Misc Feature(4)1719..1811(+)
Exon (1)1..168
Gene:SCNN1B
Gene Synonym:
Exon (2)169..487
Gene:SCNN1B
Gene Synonym:
Exon (3)488..761
Gene:SCNN1B
Gene Synonym:
Exon (4)762..952
Gene:SCNN1B
Gene Synonym:
Exon (5)953..1056
Gene:SCNN1B
Gene Synonym:
Exon (6)1057..1220
Gene:SCNN1B
Gene Synonym:
Exon (7)1221..1328
Gene:SCNN1B
Gene Synonym:
Exon (8)1329..1446
Gene:SCNN1B
Gene Synonym:
Exon (9)1447..1522
Gene:SCNN1B
Gene Synonym:
Exon (10)1523..1580
Gene:SCNN1B
Gene Synonym:
Exon (11)1581..1642
Gene:SCNN1B
Gene Synonym:
Exon (12)1643..1718
Gene:SCNN1B
Gene Synonym:
Exon (13)1719..2597
Gene:SCNN1B
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000336
Organism Homo sapiens (human)
Definition Homo sapiens sodium channel, non voltage gated 1 beta subunit (SCNN1B), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000336

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
ATGCACGTGA AGAAGTACCT GCTGAAGGGC CTGCATCGGC TGCAGAAGGG CCCCGGCTAC 
ACGTACAAGG AGCTGCTGGT GTGGTACTGC GACAACACCA ACACCCACGG CCCCAAGCGC
ATCATCTGTG AGGGGCCCAA GAAGAAAGCC ATGTGGTTCC TGCTCACCCT GCTCTTCGCC
GCCCTCGTCT GCTGGCAGTG GGGCATCTTC ATCAGGACCT ACTTGAGCTG GGAGGTCAGC
GTCTCCCTCT CCGTAGGCTT CAAGACCATG GACTTCCCTG CCGTCACCAT CTGCAATGCT
AGCCCCTTCA AGTATTCCAA AATCAAGCAT TTGCTGAAGG ACCTGGATGA GCTGATGGAA
GCTGTCCTGG AGAGAATCCT GGCTCCTGAG CTAAGCCATG CCAATGCCAC CAGGAACCTG
AACTTCTCCA TCTGGAACCA CACACCCCTG GTCCTTATTG ATGAACGGAA CCCCCACCAC
CCCATGGTCC TTGATCTCTT TGGAGACAAC CACAATGGCT TAACAAGCAG CTCAGCATCA
GAAAAGATCT GTAATGCCCA CGGGTGCAAA ATGGCCATGA GACTATGTAG CCTCAACAGG
ACCCAGTGTA CCTTCCGGAA CTTCACCAGT GCTACCCAGG CATTGACAGA GTGGTACATC
CTGCAGGCCA CCAACATCTT TGCACAGGTG CCACAGCAGG AGCTAGTAGA GATGAGCTAC
CCCGGCGAGC AGATGATCCT GGCCTGCCTA TTCGGAGCTG AGCCCTGCAA CTACCGGAAC
TTCACGTCCA TCTTCTACCC TCACTATGGC AACTGTTACA TCTTCAACTG GGGCATGACA
GAGAAGGCAC TTCCTTCGGC CAACCCTGGA ACTGAATTCG GCCTGAAGTT GATCCTGGAC
ATAGGCCAGG AAGACTACGT CCCCTTCCTT GCGTCCACGG CCGGGGTCAG GCTGATGCTT
CACGAGCAGA GGTCATACCC CTTCATCAGA GATGAGGGCA TCTACGCCAT GTCGGGGACA
GAGACGTCCA TCGGGGTACT CGTGGACAAG CTTCAGCGCA TGGGGGAGCC CTACAGCCCG
TGCACCGTGA ATGGTTCTGA GGTCCCCGTC CAAAACTTCT ACAGTGACTA CAACACGACC
TACTCCATCC AGGCCTGTCT TCGCTCCTGC TTCCAAGACC ACATGATCCG TAACTGCAAC
TGTGGCCACT ACCTGTACCC ACTGCCCCGT GGGGAGAAAT ACTGCAACAA CCGGGACTTC
CCAGACTGGG CCCATTGCTA CTCAGATCTA CAGATGAGCG TGGCGCAGAG AGAGACCTGC
ATTGGCATGT GCAAGGAGTC CTGCAATGAC ACCCAGTACA AGATGACCAT CTCCATGGCT
GACTGGCCTT CTGAGGCCTC CGAGGACTGG ATTTTCCACG TCTTGTCTCA GGAGCGGGAC
CAAAGCACCA ATATCACCCT GAGCAGGAAG GGAATTGTCA AGCTCAACAT CTACTTCCAA
GAATTTAACT ATCGCACCAT TGAAGAATCA GCAGCCAATA ACATCGTCTG GCTGCTCTCG
AATCTGGGTG GCCAGTTTGG CTTCTGGATG GGGGGCTCTG TGCTGTGCCT CATCGAGTTT
GGGGAGATCA TCATCGACTT TGTGTGGATC ACCATCATCA AGCTGGTGGC CTTGGCCAAG
AGCCTACGGC AGCGGCGAGC CCAAGCCAGC TACGCTGGCC CACCGCCCAC CGTGGCCGAG
CTGGTGGAGG CCCACACCAA CTTTGGCTTC CAGCCTGACA CGGCCCCCCG CAGCCCCAAC
ACTGGGCCCT ACCCCAGTGA GCAGGCCCTG CCCATCCCAG GCACCCCGCC CCCCAACTAT
GACTCCCTGC GTCTGCAGCC GCTGGACGTC ATCGAGTCTG ACAGTGAGGG TGATGCCATC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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