| Gene Symbol | CARD14 |
| Entrez Gene ID | 79092 |
| Full Name | caspase recruitment domain family member 14 |
| Synonyms | BIMP2,CARMA2,PRP,PSORS2,PSS1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]. |
| Disorder MIM: | |
| Disorder Html: | Psoriasis 2, 602723 (3); Pityriasis rubra pilaris, 173200 (3) |

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