Gene Symbol | SPINK7 |
Entrez Gene ID | 84651 |
Full Name | serine peptidase inhibitor, Kazal type 7 (putative) |
Synonyms | ECG2,ECRG2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » SPINK7 cDNA ORF clone
Gene Symbol | SPINK7 |
Entrez Gene ID | 84651 |
Full Name | serine peptidase inhibitor, Kazal type 7 (putative) |
Synonyms | ECG2,ECRG2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_032566.2 | NP_115955.1 | serine protease inhibitor Kazal-type 7 precursor |
NM_032566.3 | NP_115955.1 | serine protease inhibitor Kazal-type 7 precursor |
Pan troglodytes (chimpanzee) | SPINK7 | XP_001160972.1 |
Bos taurus (cattle) | SPINK7 | XP_002689329.1 |
Rattus norvegicus (Norway rat) | Spink7 | NP_001002816.2 |
SPINK7 | XP_001103960.1 | |
Canis lupus familiaris (dog) | SPINK7 | XP_003434580.2 |
Mus musculus (house mouse) | Spink7 | NP_001001803.2 |
Homo sapiens (human) | SPINK7 | NP_115955.1 |
The serine protease inhibitor of Kazal-type 7 (SPINK7) is expressed in human skin.
Weber C, Fischer J, Redelfs L, Rademacher F, Harder J, Weidinger S, Wu Z, Meyer-Hoffert U
Archives of dermatological research309(9)767-771(2017 Nov)
Hou XF, Xu LP, Song HY, Li S, Wu C, Wang JF
World journal of gastroenterology23(10)1796-1803(2017 Mar)
Negative regulation of RNA-binding protein HuR by tumor-suppressor ECRG2.
Lucchesi C, Sheikh MS, Huang Y
Oncogene35(20)2565-73(2016 05)
NMR structure note: human esophageal cancer-related gene 2.
Feng Y, Geng Y, Zhou T, Wang J
Journal of biomolecular NMR53(1)65-70(2012 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Negative regulation of RNA-binding protein HuR by tumor-suppressor ECRG2
Title: Negative regulation of RNA-binding protein HuR by tumor-suppressor ECRG2.
miR-1322 can regulate ECRG2 in an allele-specific manner and that serum levels of miR-1322 can serve as a potential diagnostic biomarker for patients with ESCC.
Title: MicroRNA-1322 regulates ECRG2 allele specifically and acts as a potential biomarker in patients with esophageal squamous cell carcinoma.
Conformational study of ECRG2 using NMR.
Title: NMR structure note: human esophageal cancer-related gene 2.
ECRG2 is a novel member of the Kazal-type serine protease inhibitor family and may function as a tumor suppressor gene regulating the protease cascades during carcinogenesis and invasion of esophageal cancer.
Title: Molecular cloning and characterization of a novel esophageal cancer related gene.
The following SPINK7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SPINK7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu25312 | |
Clone ID Related Accession (Same CDS sequence) | NM_032566.2 , NM_032566.3 | |
Accession Version | NM_032566.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-10 | |
Organism | Homo sapiens(human) | |
Product | serine protease inhibitor Kazal-type 7 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF268198.1 and AY359072.1. On Mar 17, 2004 this sequence version replaced NM_032566.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF268198.1, ERR279835.10253.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAGATCA CTGGGGGTCT CCTTCTGCTC TGTACAGTGG TCTATTTCTG TAGCAGCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_115955.1 |
CDS | 58..315 |
Translation |
Target ORF information:
Target ORF information:
|
NM_032566.2 |
1 | ATGAAGATCA CTGGGGGTCT CCTTCTGCTC TGTACAGTGG TCTATTTCTG TAGCAGCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25312 | |
Clone ID Related Accession (Same CDS sequence) | NM_032566.2 , NM_032566.3 | |
Accession Version | NM_032566.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-30 | |
Organism | Homo sapiens(human) | |
Product | serine protease inhibitor Kazal-type 7 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC091948.3, AF268198.1 and AY359072.1. On Nov 22, 2018 this sequence version replaced NM_032566.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF268198.1, ERR279835.10253.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000274565.5/ ENSP00000274565.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGAAGATCA CTGGGGGTCT CCTTCTGCTC TGTACAGTGG TCTATTTCTG TAGCAGCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_115955.1 |
CDS | 62..319 |
Translation |
Target ORF information:
Target ORF information:
|
NM_032566.3 |
1 | ATGAAGATCA CTGGGGGTCT CCTTCTGCTC TGTACAGTGG TCTATTTCTG TAGCAGCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The serine protease inhibitor of Kazal-type 7 (SPINK7) is expressed in human skin. |
|
Negative regulation of RNA-binding protein HuR by tumor-suppressor ECRG2. |
NMR structure note: human esophageal cancer-related gene 2. |