Cd3d cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Cd3d |
| Entrez Gene ID | 12500 |
| Full Name | CD3 antigen, delta polypeptide |
| Synonyms | T3d |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| XM_006509965.1 | XP_006510028.1 | T-cell surface glycoprotein CD3 delta chain isoform X1 |
| NM_013487.3 | NP_038515.3 | T-cell surface glycoprotein CD3 delta chain precursor |
| Homo sapiens (human) | CD3D | NP_000723.1 |
| CD3D | XP_001097302.1 | |
| Xenopus tropicalis (tropical clawed frog) | cd3g | NP_001135555.1 |
| Bos taurus (cattle) | CD3D | NP_001029205.1 |
| Rattus norvegicus (Norway rat) | Cd3d | NP_037301.1 |
| Mus musculus (house mouse) | Cd3d | NP_038515.3 |
| Gallus gallus (chicken) | CD3D | NP_990843.1 |
| Pan troglodytes (chimpanzee) | CD3D | XP_508789.2 |
| Canis lupus familiaris (dog) | CD3D | XP_536556.1 |
Related articles in PubMed
The effects of immune protein CD3? development and degeneration of retinal neurons after optic nerve injury.
He T, Mortensen X, Wang P, Tian N
PloS one12(4)e0175522(2017)
TCR signal strength controls thymic differentiation of discrete proinflammatory ?? T cell subsets.
Mu?oz-Ruiz M, Ribot JC, Grosso AR, Gon?alves-Sousa N, Pamplona A, Pennington DJ, Regueiro JR, Fern?ndez-Malav? E, Silva-Santos B
Nature immunology17(6)721-727(2016 06)
Ubiquitin-like protein MNSF? negatively regulates T cell function and survival.
Nakamura M, Nakagawa M, Watanabe J
Immunological investigations44(1)1-12(2015)
Polymorphisms of the T cell receptor CD3delta and CD3epsilon chains affect anti-CD3 antibody binding and T cell activation.
Boding L, Nielsen MW, Bonefeld CM, von Essen MR, Nielsen BL, Lauritsen JP, Hansen AK, Nielsen MM, Kongsbak M, Rubin M, Vennegaard MT, Odum N, Geisler C
Molecular immunology47(15)2450-7(2010 Sep)
Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors.
Kim ST, Touma M, Takeuchi K, Sun ZY, Dave VP, Kappes DJ, Wagner G, Reinherz EL
Journal of immunology (Baltimore, Md. : 1950)185(5)2951-9(2010 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Mutation of Cd3d not only impairs the proper development of amacrine cells expressing Cd3d but also those not expressing Cd3d . In contrast to effects of Major histocompatibility complex and its receptor, PirB, on other neurons, mutation of Cd3d has no effect on retinal ganglion cells death and starburst amacrine cells degeneration after optic nerve crush.
Title: The effects of immune protein CD3? development and degeneration of retinal neurons after optic nerve injury.
CD3/CD28-inducible MNSFbeta-Bcl-G complex may be involved in the regulation of T cell function and survival.
Title: Ubiquitin-like protein MNSF? negatively regulates T cell function and survival.
Polymorphisms of the CD3delta ectodomain exist in mice,some of which lead to amino acid substitutions which cause structural changes and affect anti-CD3 antibody binding.
Title: Polymorphisms of the T cell receptor CD3delta and CD3epsilon chains affect anti-CD3 antibody binding and T cell activation.
CD3gammaepsilon dimers predominated over CD3deltaepsilon dimers at the early stage of T cell development.
Title: Dynamics of CD3gammaepsilon and CD3deltaepsilon dimer expression during murine T cell development.
CD3delta transgene rescues gammadelta T cell development in mice lacking both mouse CD3delta and CD3gamma.
Title: Different composition of the human and the mouse gammadelta T cell receptor explains different phenotypes of CD3gamma and CD3delta immunodeficiencies.
The following Cd3d gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd3d cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu09470 | |
| Clone ID Related Accession (Same CDS sequence) | NM_013487.3 | |
| Accession Version | NM_013487.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-16 | |
| Organism | Mus musculus(house mouse) | |
| Product | T-cell surface glycoprotein CD3 delta chain precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK042172.1, BC062807.1, BB237678.2 and BY576367.1. On Apr 25, 2009 this sequence version replaced NM_013487.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK042172.1, AK154064.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGAACACA GCGGGATTCT GGCTAGTCTG ATACTGATTG CTGTTCTCCC CCAAGGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_038515.3 |
| CDS | 101..622 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_013487.3 |
ORF Insert Sequence:
1 | ATGGAACACA GCGGGATTCT GGCTAGTCTG ATACTGATTG CTGTTCTCCC CCAAGGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu41970 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006509965.1 | |
| Accession Version | XM_006509965.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | T-cell surface glycoprotein CD3 delta chain isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGAACACA GCGGGATTCT GGCTAGTCTG ATACTGATTG CTGTTCTCCC CCAAGGTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006510028.1 |
| CDS | 118..804 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006509965.1 |
ORF Insert Sequence:
1 | ATGGAACACA GCGGGATTCT GGCTAGTCTG ATACTGATTG CTGTTCTCCC CCAAGGTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
The effects of immune protein CD3? development and degeneration of retinal neurons after optic nerve injury. |
|
TCR signal strength controls thymic differentiation of discrete proinflammatory ?? T cell subsets. |
|
Ubiquitin-like protein MNSF? negatively regulates T cell function and survival. |
|
Polymorphisms of the T cell receptor CD3delta and CD3epsilon chains affect anti-CD3 antibody binding and T cell activation. |
|
Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors. |