Gene Symbol | Fgf4 |
Entrez Gene ID | 14175 |
Full Name | fibroblast growth factor 4 |
Synonyms | Fgf-4,Fgfk,HBGF-4,Hst1,Hstf-1,KS3,hst,hst-1,kFGF |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Fgf4 cDNA ORF clone
Gene Symbol | Fgf4 |
Entrez Gene ID | 14175 |
Full Name | fibroblast growth factor 4 |
Synonyms | Fgf-4,Fgfk,HBGF-4,Hst1,Hstf-1,KS3,hst,hst-1,kFGF |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_010202.6 | NP_034332.2 | fibroblast growth factor 4 precursor |
FGF4 | XP_001100747.1 | |
Xenopus tropicalis (tropical clawed frog) | fgf4 | NP_001136294.1 |
Homo sapiens (human) | FGF4 | NP_001998.1 |
Bos taurus (cattle) | FGF4 | NP_001035695.2 |
Danio rerio (zebrafish) | fgf4 | NP_571710.1 |
Pan troglodytes (chimpanzee) | FGF4 | XP_001173970.1 |
Canis lupus familiaris (dog) | FGF4 | XP_540801.2 |
Mus musculus (house mouse) | Fgf4 | NP_034332.2 |
Rattus norvegicus (Norway rat) | Fgf4 | NP_446261.1 |
Gallus gallus (chicken) | FGF4 | NP_001026717.1 |
O-GlcNAc on PKC? Inhibits the FGF4-PKC?-MEK-ERK1/2 Pathway via Inhibition of PKC? Phosphorylation in Mouse Embryonic Stem Cells.
Miura T, Kume M, Kawamura T, Yamamoto K, Hamakubo T, Nishihara S
Stem cell reports10(1)272-286(2018 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
the paternal genome facilitates the proliferation of trophoblast cells without FGF4 signaling
Title: Cell proliferation potency is independent of FGF4 signaling in trophoblast stem cells derived from androgenetic embryos.
There was intense Fgf4 expression observed in the PEK of the cap-stage tooth germ at E14. At E15, Fgf4 became sparse in the epithelium except for the PEK. Fgf4 was exclusively expressed in the apical end of the labial epithelium during E16-18
Title: The enamel knot-like structure is eternally maintained in the apical bud of postnatal mouse incisors.
With efficient chimera-forming capability using a medium containing fibroblast growth factor (FGF)-4.
Title: Establishment of a primed pluripotent epiblast stem cell in FGF4-based conditions.
the amount of FGF4 is limited and regulates PE/EPI proportions in the mouse embryo.
Title: FGF4 is a limiting factor controlling the proportions of primitive endoderm and epiblast in the ICM of the mouse blastocyst.
The following Fgf4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fgf4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu23069 | |
Clone ID Related Accession (Same CDS sequence) | NM_010202.6 | |
Accession Version | NM_010202.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 609bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Mus musculus(house mouse) | |
Product | fibroblast growth factor 4 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK082814.1, AC161763.3 and BB398533.1. On Nov 29, 2016 this sequence version replaced NM_010202.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK082814.1, BY728839.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGAAAC GCGGGCCGAC CACAGGGACG CTGCTGCCCA GGGTCCTGCT GGCCCTGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_034332.2 |
CDS | 120..728 |
Translation |
Target ORF information:
Target ORF information:
|
NM_010202.6 |
1 | ATGGCGAAAC GCGGGCCGAC CACAGGGACG CTGCTGCCCA GGGTCCTGCT GGCCCTGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
O-GlcNAc on PKC? Inhibits the FGF4-PKC?-MEK-ERK1/2 Pathway via Inhibition of PKC? Phosphorylation in Mouse Embryonic Stem Cells. |