Gene Symbol | Gspt1 |
Entrez Gene ID | 14852 |
Full Name | G1 to S phase transition 1 |
Synonyms | AI314175,AI326449,AV307676,C79774,G1st,Gst-1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Gspt1 cDNA ORF clone
gRNAs
Gene Symbol | Gspt1 |
Entrez Gene ID | 14852 |
Full Name | G1 to S phase transition 1 |
Synonyms | AI314175,AI326449,AV307676,C79774,G1st,Gst-1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_146066.2 | NP_666178.2 | eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform 1 |
NM_001130008.1 | NP_001123480.1 | eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform 2 |
Pan troglodytes (chimpanzee) | GSPT1 | XP_001140542.3 |
Rattus norvegicus (Norway rat) | Gspt1 | NP_001003978.1 |
Gallus gallus (chicken) | GSPT1 | NP_001129149.1 |
Saccharomyces cerevisiae (baker's yeast) | SUP35 | NP_010457.3 |
Homo sapiens (human) | GSPT1 | NP_001123478.1 |
Danio rerio (zebrafish) | gspt1 | NP_001003992.1 |
Kluyveromyces lactis | KLLA0D17424g | XP_453831.1 |
Oryza sativa (rice) | Os04g0270100 | NP_001052341.1 |
LOC716860 | XP_001107851.2 | |
Bos taurus (cattle) | GSPT1 | NP_001091540.2 |
Mus musculus (house mouse) | Gspt1 | NP_001123480.1 |
Rattus norvegicus (Norway rat) | LOC100911685 | XP_006245802.1 |
Eremothecium gossypii | AGOS_AGL145W | NP_986522.2 |
Danio rerio (zebrafish) | gspt1l | NP_942101.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009310 | XP_320105.3 |
Schizosaccharomyces pombe (fission yeast) | sup35 | NP_588225.1 |
Neurospora crassa | NCU04790 | XP_960416.1 |
Arabidopsis thaliana (thale cress) | AT1G18070 | NP_001185026.1 |
Canis lupus familiaris (dog) | GSPT1 | XP_005621589.1 |
Drosophila melanogaster (fruit fly) | Elf | NP_001260415.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_00449 | XP_003718618.1 |
Xenopus tropicalis (tropical clawed frog) | gspt1 | NP_001015805.2 |
A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury.
Ishii T, Ueyama T, Shigyo M, Kohta M, Kondoh T, Kuboyama T, Uebi T, Hamada T, Gutmann DH, Aiba A, Kohmura E, Tohda C, Saito N
The Journal of biological chemistry292(4)1240-1250(2017 01)
Functional role of Tia1/Pub1 and Sup35 prion domains: directing protein synthesis machinery to the tubulin cytoskeleton.
Li X, Rayman JB, Kandel ER, Derkatch IL
Molecular cell55(2)305-18(2014 Jul)
HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1.
Figaro S, Scrima N, Buckingham RH, Heurgu?-Hamard V
FEBS letters582(16)2352-6(2008 Jul)
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)
Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1.
Hoshino S, Imai M, Mizutani M, Kikuchi Y, Hanaoka F, Ui M, Katada T
The Journal of biological chemistry273(35)22254-9(1998 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rac1-GSPT1 represents a novel signaling axis in astrocytes that accelerates proliferation in response to inflammation, which is one important factor in the development of astrogliosis/glial scar following CNS injury
Title: A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury.
The following Gspt1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gspt1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu21502 | |
Clone ID Related Accession (Same CDS sequence) | NM_146066.2 | |
Accession Version | NM_146066.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1911bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-21 | |
Organism | Mus musculus(house mouse) | |
Product | eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB631229.1, AK148603.1, AC087541.23 and CJ260597.1. On Jul 10, 2008 this sequence version replaced NM_146066.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK148603.1, AK030760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGATCCTA GCAGCGGCGG TGGCGGCGGT GGCGGCGGCG GCGGGAGCAG CAGCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_666178.2 |
CDS | 329..2239 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGATCCTA GCAGCGGCGG TGGCGGCGGT GGCGGCGGCG GCGGGAGCAG CAGCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21503 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130008.1 | |
Accession Version | NM_001130008.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1908bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-21 | |
Organism | Mus musculus(house mouse) | |
Product | eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB631229.1, AK148603.1, AK032059.1, AC087541.23 and CJ260597.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in an internal exon, compared to variant 1, resulting in an isoform (2) that is 1 aa shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK032059.1, AB003502.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGATCCTA GCAGCGGCGG TGGCGGCGGT GGCGGCGGCG GCGGGAGCAG CAGCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123480.1 |
CDS | 329..2236 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGATCCTA GCAGCGGCGG TGGCGGCGGT GGCGGCGGCG GCGGGAGCAG CAGCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury. |
Functional role of Tia1/Pub1 and Sup35 prion domains: directing protein synthesis machinery to the tubulin cytoskeleton. |
HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1. |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1. |