Gene Symbol | Selenbp1 |
Entrez Gene ID | 20341 |
Full Name | selenium binding protein 1 |
Synonyms | Lp56,Lpsb,SBP56 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Selenbp1 cDNA ORF clone
Gene Symbol | Selenbp1 |
Entrez Gene ID | 20341 |
Full Name | selenium binding protein 1 |
Synonyms | Lp56,Lpsb,SBP56 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_009150.3 | NP_033176.2 | methanethiol oxidase |
SELENBP1 | XP_001107660.2 | |
Canis lupus familiaris (dog) | SELENBP1 | XP_005630863.1 |
Mus musculus (house mouse) | Selenbp2 | NP_062287.1 |
Rattus norvegicus (Norway rat) | Selenbp1 | XP_006232994.1 |
Gallus gallus (chicken) | LOC100859776 | XP_004948391.1 |
Gallus gallus (chicken) | SELENBP1 | NP_001264739.1 |
Drosophila melanogaster (fruit fly) | CG7966 | NP_650256.2 |
Arabidopsis thaliana (thale cress) | SBP3 | NP_189022.1 |
Oryza sativa (rice) | Os01g0916400 | NP_001045194.1 |
Gallus gallus (chicken) | LOC425662 | XP_004948427.1 |
Danio rerio (zebrafish) | selenbp1 | NP_956864.1 |
Arabidopsis thaliana (thale cress) | SBP2 | NP_193140.1 |
Arabidopsis thaliana (thale cress) | SBP1 | NP_001190723.1 |
Pan troglodytes (chimpanzee) | SELENBP1 | XP_524867.3 |
Bos taurus (cattle) | SELENBP1 | NP_001039513.1 |
Mus musculus (house mouse) | Selenbp1 | NP_033176.2 |
Gallus gallus (chicken) | LOC100857226 | XP_004948397.1 |
Xenopus tropicalis (tropical clawed frog) | selenbp1 | NP_001016750.1 |
Homo sapiens (human) | SELENBP1 | NP_001245218.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011531 | XP_309978.4 |
Caenorhabditis elegans (roundworm) | CELE_Y37A1B.5 | NP_001255777.1 |
Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis.
Pol A, Renkema GH, Tangerman A, Winkel EG, Engelke UF, de Brouwer APM, Lloyd KC, Araiza RS, van den Heuvel L, Omran H, Olbrich H, Oude Elberink M, Gilissen C, Rodenburg RJ, Sass JO, Schwab KO, Sch?fer H, Venselaar H, Sequeira JS, Op den Camp HJM, Wevers RA
Nature genetics50(1)120-129(2018 Jan)
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results have revealed a novel mechanism that SELENBP1-mediated cancer inhibition is through altering lipid/glucose metabolic signaling pathways.
Title: Quantitative proteomic analysis reveals that anti-cancer effects of selenium-binding protein 1 in vivo are associated with metabolic pathways.
Selenbp1 suppresses the expression of tumor-promoting genes
Title: Selenium-binding protein 1: its physiological function, dependence on aryl hydrocarbon receptors, and role in wasting syndrome by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
SBP1 has tumor suppressor functions that are inhibited in colorectal cancer through epigenetic silencing
Title: Transcriptional regulation and biological functions of selenium-binding protein 1 in colorectal cancer in vitro and in nude mouse xenografts.
The following Selenbp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Selenbp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu03615 | |
Clone ID Related Accession (Same CDS sequence) | NM_009150.3 | |
Accession Version | NM_009150.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1419bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-23 | |
Organism | Mus musculus(house mouse) | |
Product | methanethiol oxidase | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC087062.25. On Nov 17, 2006 this sequence version replaced NM_009150.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011202.1, M32032.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCTACAA AATGCACAAA GTGTGGTCCA GGTTACTCCA CCCCTCTGGA GGCCATGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_033176.2 |
CDS | 77..1495 |
Translation |
Target ORF information:
Target ORF information:
|
NM_009150.3 |
1 | ATGGCTACAA AATGCACAAA GTGTGGTCCA GGTTACTCCA CCCCTCTGGA GGCCATGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis. |
High-throughput discovery of novel developmental phenotypes. |