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PLSCR1 cDNA ORF clone, Mus musculus(House mouse)

Summary

Gene Symbol PLSCR1
Entrez Gene ID 22038
Full Name phospholipid scramblase 1
Synonyms MmTRA1a,MmTRA1b,Nor1,Tra1,Tra1a,Tra1b,Tras1,Tras2
General protein information
Preferred Names

phospholipid scramblase 1

Names

phospholipid scramblase 1
PL scramblase 1
ca(2+)-dependent phospholipid scramblase 1
transplantability-associated protein 1
Gene Type protein-coding
Organism Mus musculus(House mouse)
Genome

9

9|9 E3.3

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006511052.4 XP_006511115.1 phospholipid scramblase 1 isoform X1
NM_011636.2 NP_035766.2 phospholipid scramblase 1
XM_006511052.3 XP_006511115.1 phospholipid scramblase 1 isoform X1
XM_006511052.2 XP_006511115.1 phospholipid scramblase 1 isoform X1

Pathways from BioSystems


Homologies


Danio rerio (zebrafish) plscr3a NP_001098583.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP005498 XP_001688666.1
Homo sapiens (human) PLSCR1 NP_066928.1
Rattus norvegicus (Norway rat) Plscr1 NP_476542.1
Drosophila melanogaster (fruit fly) scramb1 NP_648389.3
Anopheles gambiae (African malaria mosquito) AgaP_AGAP005504 XP_001688668.1
Caenorhabditis elegans (roundworm) scrm-3 NP_503934.2
Xenopus tropicalis (tropical clawed frog) LOC100489273 XP_002938452.2
Pan troglodytes (chimpanzee) PLSCR1 XP_001135229.2
PLSCR1 XP_001111222.1
Mus musculus (house mouse) Plscr1 NP_035766.2
Gallus gallus (chicken) PLSCR1 XP_001231237.1
Danio rerio (zebrafish) plscr3b NP_998031.1
Caenorhabditis elegans (roundworm) scrm-2 NP_493321.1
Xenopus tropicalis (tropical clawed frog) plscr1 NP_001135607.1
Canis lupus familiaris (dog) LOC611500 XP_005634707.1
Caenorhabditis elegans (roundworm) scrm-1 NP_492976.2

Gene Ontology


Bibliography

Related articles in PubMed

Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia.
Tufail Y, Cook D, Fourgeaud L, Powers CJ, Merten K, Clark CL, Hoffman E, Ngo A, Sekiguchi KJ, O'Shea CC, Lemke G, Nimmerjahn A
Neuron93(3)574-586.e8(2017 Feb)

Phospholipid scramblase 1 amplifies anaphylactic reactions in vivo.
Kassas-Guediri A, Coudrat J, Pacreau E, Launay P, Monteiro RC, Blank U, Charles N, Benhamou M
PloS one12(3)e0173815(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

IgE receptor type I-dependent tyrosine phosphorylation of phospholipid scramblase.
Pastorelli C, Veiga J, Charles N, Voignier E, Moussu H, Monteiro RC, Benhamou M
The Journal of biological chemistry276(23)20407-12(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Genetic knockdown of PLSCR1 activity reduces intracellular calcium dysregulation, prevents phosphatidylserine externalization, and enables months-long protection of vector-transduced, transgene-expressing cells from microglial phagocytosis.
Title: Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia.

PLSCR1 aggravates anaphylactic reactions by increasing Fc epsion RI-dependent mast cell degranulation.
Title: Phospholipid scramblase 1 amplifies anaphylactic reactions in vivo.

Phospholipid scramblase 1 regulates phosphatidylserine exposure in response to oxygen stress, leading to beta2-glycoprotein I and IgM binding and lipid-mediated, inflammatory responses.
Title: Phospholipid scramblase 1 is required for ?2-glycoprotein I binding in hypoxia and reoxygenation-induced endothelial inflammation.

Lipopolysaccharide treatment resulted in increased expression of phospholipid scramblase 1(PLSCR-1) and decrease in phospholipid scramblase 4(Plscr4 )messenger RNA demonstrating modulation of PLSCR-1 and PLSCR-4 in lipopolysaccharide-induced preterm birth
Title: Phospholipid scramblase expression in the pregnant mouse uterus in LPS-induced preterm delivery.

Study demonstrates that PLSCR1 is a TLR9-interacting protein that plays an important role in pDC's type 1 IFN responses by regulating TLR9 trafficking to the endosomal compartment.
Title: Phospholipid scramblase 1 regulates Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells.

The following PLSCR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLSCR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu08499 NM_011636.2
Latest version!		 Mus musculus phospholipid scramblase 1 (Plscr1), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
OMu08499 XM_006511052.4
Latest version!		 Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
View Old Accession Versions >>
OMu08499 XM_006511052.3 Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
OMu08499 XM_006511052.2 Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu08499
Clone ID Related Accession (Same CDS sequence) XM_006511052.4 , NM_011636.2 , XM_006511052.3 , XM_006511052.2
Accession Version NM_011636.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 987bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-27
Organism Mus musculus(house mouse)
Product phospholipid scramblase 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CK788898.1, AF159593.1, AK003628.1 and CJ213207.1. On Jul 19, 2008 this sequence version replaced NM_011636.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK003628.1, AF159593.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_035766.2
CDS182..1168
Translation

Target ORF information:

RefSeq Version NM_011636.2
Organism Mus musculus(house mouse)
Definition Mus musculus phospholipid scramblase 1 (Plscr1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_011636.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu08499
Clone ID Related Accession (Same CDS sequence) XM_006511052.4 , NM_011636.2 , XM_006511052.3 , XM_006511052.2
Accession Version XM_006511052.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 987bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product phospholipid scramblase 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006511052.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006511115.1
CDS236..1222
Translation

Target ORF information:

RefSeq Version XM_006511052.3
Organism Mus musculus(house mouse)
Definition Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006511052.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu08499
Clone ID Related Accession (Same CDS sequence) XM_006511052.4 , NM_011636.2 , XM_006511052.3 , XM_006511052.2
Accession Version XM_006511052.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 987bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-02-08
Organism Mus musculus(House mouse)
Product phospholipid scramblase 1 isoform X1
Comment 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006511115.1
Translation

Target ORF information:

RefSeq Version XM_006511052.2
Organism Mus musculus(House mouse)
Definition Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006511052.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu08499
Clone ID Related Accession (Same CDS sequence) XM_006511052.4 , NM_011636.2 , XM_006511052.3 , XM_006511052.2
Accession Version XM_006511052.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 987bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product phospholipid scramblase 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006511052.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006511115.1
CDS105..1091
Translation

Target ORF information:

RefSeq Version XM_006511052.4
Organism Mus musculus(house mouse)
Definition Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006511052.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia.
Neuron93(3)574-586.e8(2017 Feb)
Tufail Y,Cook D,Fourgeaud L,Powers CJ,Merten K,Clark CL,Hoffman E,Ngo A,Sekiguchi KJ,O'Shea CC,Lemke G,Nimmerjahn A


book

Phospholipid scramblase 1 amplifies anaphylactic reactions in vivo.
PloS one12(3)e0173815(2017)
Kassas-Guediri A,Coudrat J,Pacreau E,Launay P,Monteiro RC,Blank U,Charles N,Benhamou M


book

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA


book

IgE receptor type I-dependent tyrosine phosphorylation of phospholipid scramblase.
The Journal of biological chemistry276(23)20407-12(2001 Jun)
Pastorelli C,Veiga J,Charles N,Voignier E,Moussu H,Monteiro RC,Benhamou M