Gene Symbol | PLSCR1 |
Entrez Gene ID | 5359 |
Full Name | phospholipid scramblase 1 |
Synonyms | MMTRA1B |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » PLSCR1 cDNA ORF clone
gRNAs
Gene Symbol | PLSCR1 |
Entrez Gene ID | 5359 |
Full Name | phospholipid scramblase 1 |
Synonyms | MMTRA1B |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001363874.1 | NP_001350803.1 | phospholipid scramblase 1 isoform 3 |
NM_021105.3 | NP_066928.1 | phospholipid scramblase 1 isoform 1 |
NM_001363872.1 | NP_001350801.1 | phospholipid scramblase 1 isoform 2 |
XM_011512907.2 | XP_011511209.1 | phospholipid scramblase 1 isoform X4 |
XM_017006629.1 | XP_016862118.1 | phospholipid scramblase 1 isoform X2 |
XM_011512906.2 | XP_011511208.1 | phospholipid scramblase 1 isoform X4 |
NM_021105.2 | NP_066928.1 | phospholipid scramblase 1 |
XM_017006628.1 | XP_016862117.1 | phospholipid scramblase 1 isoform X1 |
XM_011512905.1 | XP_011511207.1 | phospholipid scramblase 1 isoform X3 |
XM_011512904.1 | XP_011511206.1 | phospholipid scramblase 1 isoform X2 |
XM_005247538.3 | XP_005247595.1 | phospholipid scramblase 1 isoform X4 |
Danio rerio (zebrafish) | plscr3a | NP_001098583.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005498 | XP_001688666.1 |
Homo sapiens (human) | PLSCR1 | NP_066928.1 |
Rattus norvegicus (Norway rat) | Plscr1 | NP_476542.1 |
Drosophila melanogaster (fruit fly) | scramb1 | NP_648389.3 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005504 | XP_001688668.1 |
Caenorhabditis elegans (roundworm) | scrm-3 | NP_503934.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100489273 | XP_002938452.2 |
Pan troglodytes (chimpanzee) | PLSCR1 | XP_001135229.2 |
PLSCR1 | XP_001111222.1 | |
Mus musculus (house mouse) | Plscr1 | NP_035766.2 |
Gallus gallus (chicken) | PLSCR1 | XP_001231237.1 |
Danio rerio (zebrafish) | plscr3b | NP_998031.1 |
Caenorhabditis elegans (roundworm) | scrm-2 | NP_493321.1 |
Xenopus tropicalis (tropical clawed frog) | plscr1 | NP_001135607.1 |
Canis lupus familiaris (dog) | LOC611500 | XP_005634707.1 |
Caenorhabditis elegans (roundworm) | scrm-1 | NP_492976.2 |
Herpes simplex viruses activate phospholipid scramblase to redistribute phosphatidylserines and Akt to the outer leaflet of the plasma membrane and promote viral entry.
Cheshenko N, Pierce C, Herold BC
PLoS pathogens14(1)e1006766(2018 Jan)
Interactions stabilizing the C-terminal helix of human phospholipid scramblase 1 in lipid bilayers: A computational study.
Venken T, Schillinger AS, Fuglebakk E, Reuter N
Biochimica et biophysica acta1859(7)1200-1210(2017 07)
PLSCR1/IP3R1/Ca
Li H, Xu J, Zhou Y, Liu X, Shen LE, Zhu YU, Li Z, Wang X, Guo Q, Hui H
Cell death & disease8(5)e2768(2017 May)
Phospholipid scramblase 1 as a critical node at the crossroad between autophagy and apoptosis in mantle cell lymphoma.
Mastorci K, Montico B, Fa? DA, Sigalotti L, Ponzoni M, Inghirami G, Dolcetti R, Dal Col J
Oncotarget7(27)41913-41928(2016 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
investigate how the polar aspartate residue is accommodated in lipid bilayers containing POPC with and without cholesterol, using all-atom molecular dynamics simulations
Title: Interactions stabilizing the C-terminal helix of human phospholipid scramblase 1 in lipid bilayers: A computational study.
Data indicate heterogeneous expression of phospholipid scramblase 1 (PLSCR1) and suggest its possible implication in the response to anticancer therapies, especially to drugs promoting protective autophagy.
Title: Phospholipid scramblase 1 as a critical node at the crossroad between autophagy and apoptosis in mantle cell lymphoma.
Human phospholipid scramblase 1 has five histidine residues and point mutations of histidine residues to alanine in hPLSCR1 resulted in 60 % loss in nuclease activity.
Title: Identification and characterization of the novel nuclease activity of human phospholipid scramblase 1.
directed mutagenesis revealed the importance of c-Myc binding sites from -751 to -756 and -548 to -553 on the promoter of hPLSCR1in transcriptionally regulating the expression of hPLSCR1.
Title: Two c-Myc binding sites are crucial in upregulating the expression of human phospholipid scramblase 1 gene.
PLSCR1 positively regulates hepatic carcinoma cell proliferation and migration through interacting with midkine
Title: Phospholipid Scramblase 1 Interacts with Midkine and Regulates Hepatic Cancer Cell Proliferation and Migration.
The following PLSCR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLSCR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu09066![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_021105.3 , XM_017006629.1 , NM_021105.2 , XM_011512904.1 | |
Accession Version | NM_021105.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-06 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF098642.1 and BC032718.1. On Nov 23, 2018 this sequence version replaced NM_021105.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC032718.1, AF098642.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000342435.9/ ENSP00000345494.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGACAAAC AAAACTCACA GATGAATGCT TCTCACCCGG AAACAAACTT GCCAGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_066928.1 |
CDS | 155..1111 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGACAAAC AAAACTCACA GATGAATGCT TCTCACCCGG AAACAAACTT GCCAGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu09066![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_021105.3 , XM_017006629.1 , NM_021105.2 , XM_011512904.1 | |
Accession Version | NM_021105.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-11-26 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DR005513.1, AF098642.1 and BC032718.1. On Apr 8, 2008 this sequence version replaced NM_021105.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC032718.1, AB006746.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGACAAAC AAAACTCACA GATGAATGCT TCTCACCCGG AAACAAACTT GCCAGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_066928.1 |
CDS | 389..1345 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGACAAAC AAAACTCACA GATGAATGCT TCTCACCCGG AAACAAACTT GCCAGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu09066![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_021105.3 , XM_017006629.1 , NM_021105.2 , XM_011512904.1 | |
Accession Version | XM_017006629.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACAAAC AAAACTCACA GATGAATGCT TCTCACCCGG AAACAAACTT GCCAGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016862118.1 |
CDS | 449..1405 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGACAAAC AAAACTCACA GATGAATGCT TCTCACCCGG AAACAAACTT GCCAGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu09066![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_021105.3 , XM_017006629.1 , NM_021105.2 , XM_011512904.1 | |
Accession Version | XM_011512904.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACAAAC AAAACTCACA GATGAATGCT TCTCACCCGG AAACAAACTT GCCAGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011511206.1 |
CDS | 204..1160 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGACAAAC AAAACTCACA GATGAATGCT TCTCACCCGG AAACAAACTT GCCAGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu37983 | |
Clone ID Related Accession (Same CDS sequence) | NM_001363874.1 , XM_011512907.2 , XM_011512906.2 , XM_005247538.3 | |
Accession Version | NM_001363874.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-06 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC116544.1 and AC069528.10. On Jun 3, 2018 this sequence version replaced XM_011512907.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.307568.1, SRR1163657.278721.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGCTTCTCA CCCGGAAACA AACTTGCCAG TTGGGTATCC TCCTCAGTAT CCACCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001350803.1 |
CDS | 142..855 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCTTCTCA CCCGGAAACA AACTTGCCAG TTGGGTATCC TCCTCAGTAT CCACCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu59784 | |
Clone ID Related Accession (Same CDS sequence) | NM_001363872.1 , XM_011512905.1 | |
Accession Version | NM_001363872.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-06 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC116544.1 and AC069528.10. On Jun 3, 2018 this sequence version replaced XM_011512905.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.480895.1, SRR1803617.349593.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGAATGCTT CTCACCCGGA AACAAACTTG CCAGTTGGGT ATCCTCCTCA GTATCCACCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001350801.1 |
CDS | 98..1033 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAATGCTT CTCACCCGGA AACAAACTTG CCAGTTGGGT ATCCTCCTCA GTATCCACCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu37983 | |
Clone ID Related Accession (Same CDS sequence) | NM_001363874.1 , XM_011512907.2 , XM_011512906.2 , XM_005247538.3 | |
Accession Version | XM_011512907.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512907.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTTCTCA CCCGGAAACA AACTTGCCAG TTGGGTATCC TCCTCAGTAT CCACCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011511209.1 |
CDS | 352..1065 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCTTCTCA CCCGGAAACA AACTTGCCAG TTGGGTATCC TCCTCAGTAT CCACCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu37983 | |
Clone ID Related Accession (Same CDS sequence) | NM_001363874.1 , XM_011512907.2 , XM_011512906.2 , XM_005247538.3 | |
Accession Version | XM_011512906.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512906.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTTCTCA CCCGGAAACA AACTTGCCAG TTGGGTATCC TCCTCAGTAT CCACCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011511208.1 |
CDS | 427..1140 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCTTCTCA CCCGGAAACA AACTTGCCAG TTGGGTATCC TCCTCAGTAT CCACCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu37983 | |
Clone ID Related Accession (Same CDS sequence) | NM_001363874.1 , XM_011512907.2 , XM_011512906.2 , XM_005247538.3 | |
Accession Version | XM_005247538.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005247538.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTTCTCA CCCGGAAACA AACTTGCCAG TTGGGTATCC TCCTCAGTAT CCACCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005247595.1 |
CDS | 378..1091 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCTTCTCA CCCGGAAACA AACTTGCCAG TTGGGTATCC TCCTCAGTAT CCACCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu59784 | |
Clone ID Related Accession (Same CDS sequence) | NM_001363872.1 , XM_011512905.1 | |
Accession Version | XM_011512905.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATGCTT CTCACCCGGA AACAAACTTG CCAGTTGGGT ATCCTCCTCA GTATCCACCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011511207.1 |
CDS | 280..1215 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAATGCTT CTCACCCGGA AACAAACTTG CCAGTTGGGT ATCCTCCTCA GTATCCACCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu94291 | |
Clone ID Related Accession (Same CDS sequence) | XM_017006628.1 | |
Accession Version | XM_017006628.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | phospholipid scramblase 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACAAAC AAAACTCACA GATGAATGCT TCTCACCCGG AAACAAACTT GCCAGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016862117.1 |
CDS | 281..1240 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGACAAAC AAAACTCACA GATGAATGCT TCTCACCCGG AAACAAACTT GCCAGTTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Herpes simplex viruses activate phospholipid scramblase to redistribute phosphatidylserines and Akt to the outer leaflet of the plasma membrane and promote viral entry. |
Interactions stabilizing the C-terminal helix of human phospholipid scramblase 1 in lipid bilayers: A computational study. |
PLSCR1/IP3R1/Ca |
Phospholipid scramblase 1 as a critical node at the crossroad between autophagy and apoptosis in mantle cell lymphoma. |