Gene Symbol | Upk1b |
Entrez Gene ID | 22268 |
Full Name | uroplakin 1B |
Synonyms | AI413235,Tspan20,UPIb,Upk1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Upk1b cDNA ORF clone
Gene Symbol | Upk1b |
Entrez Gene ID | 22268 |
Full Name | uroplakin 1B |
Synonyms | AI413235,Tspan20,UPIb,Upk1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017316943.1 | XP_017172432.1 | uroplakin-1b isoform X1 |
XM_017316943.2 | XP_017172432.1 | uroplakin-1b isoform X1 |
NM_178924.4 | NP_849255.2 | uroplakin-1b |
UPK1B | XP_001108219.1 | |
Bos taurus (cattle) | UPK1B | NP_776907.2 |
Rattus norvegicus (Norway rat) | Upk1b | NP_001019424.1 |
Homo sapiens (human) | UPK1B | NP_008883.2 |
Mus musculus (house mouse) | Upk1b | NP_849255.2 |
Xenopus tropicalis (tropical clawed frog) | upk1b | NP_001037968.1 |
Gallus gallus (chicken) | UPK1B | XP_416567.3 |
Pan troglodytes (chimpanzee) | UPK1B | XP_526274.3 |
Canis lupus familiaris (dog) | UPK1B | XP_850140.2 |
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Rutledge EA, Benazet JD, McMahon AP
Development (Cambridge, England)144(17)3177-3188(2017 09)
A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development.
Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, L?dtke TH, Trowe MO, Kispert A
PLoS genetics13(8)e1006951(2017 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Upk1b expression is critical for urothelial plaque stability, maturation, differentiation, and homeostasis of urothelium. Report CAKUT in Upk1b knockout mice.
Title: Uroplakin 1b is critical in urinary tract development and urothelial differentiation and homeostasis.
The despites a lower level of expression, UPIb maintain its plaque association in urothelial preneoplastic lesions.
Title: Expression and localization of four uroplakins in urothelial preneoplastic lesions.
analysis of glycan structures of uroplakins Ia and Ib
Title: Distinct glycan structures of uroplakins Ia and Ib: structural basis for the selective binding of FimH adhesin to uroplakin Ia.
structure of the major membrane protein complex from urinary bladder epithelial cells by cryoelectron crystallography
Title: Structure of the major membrane protein complex from urinary bladder epithelial cells by cryo-electron crystallography.
The following Upk1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Upk1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu07909 | |
Clone ID Related Accession (Same CDS sequence) | XM_017316943.1 , XM_017316943.2 , NM_178924.4 | |
Accession Version | NM_178924.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-16 | |
Organism | Mus musculus(house mouse) | |
Product | uroplakin-1b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK053004.1, AK086926.1, AK083101.1, BB427704.2 and D18653.1. On May 15, 2008 this sequence version replaced NM_178924.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC046604.1, AK083101.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCAAAG ACGATTCCAC TGTTCGTTGC TTCCAGGGCC TGTTGATTTT TGGACACGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_849255.2 |
CDS | 76..858 |
Translation |
Target ORF information:
Target ORF information:
|
NM_178924.4 |
1 | ATGGCCAAAG ACGATTCCAC TGTTCGTTGC TTCCAGGGCC TGTTGATTTT TGGACACGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07909 | |
Clone ID Related Accession (Same CDS sequence) | XM_017316943.1 , XM_017316943.2 , NM_178924.4 | |
Accession Version | XM_017316943.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | uroplakin-1b isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAAAG ACGATTCCAC TGTTCGTTGC TTCCAGGGCC TGTTGATTTT TGGACACGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017172432.1 |
CDS | 128..910 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017316943.1 |
1 | ATGGCCAAAG ACGATTCCAC TGTTCGTTGC TTCCAGGGCC TGTTGATTTT TGGACACGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07909 | |
Clone ID Related Accession (Same CDS sequence) | XM_017316943.1 , XM_017316943.2 , NM_178924.4 | |
Accession Version | XM_017316943.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | uroplakin-1b isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017316943.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAAAG ACGATTCCAC TGTTCGTTGC TTCCAGGGCC TGTTGATTTT TGGACACGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017172432.1 |
CDS | 129..911 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017316943.2 |
1 | ATGGCCAAAG ACGATTCCAC TGTTCGTTGC TTCCAGGGCC TGTTGATTTT TGGACACGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. |
A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. |