Gene Symbol | Dguok |
Entrez Gene ID | 27369 |
Full Name | deoxyguanosine kinase |
Synonyms | dGK,dGK1,dGK2,dGK3 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Dguok cDNA ORF clone
gRNAs
Gene Symbol | Dguok |
Entrez Gene ID | 27369 |
Full Name | deoxyguanosine kinase |
Synonyms | dGK,dGK1,dGK2,dGK3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017321604.2 | XP_017177093.1 | deoxyguanosine kinase, mitochondrial isoform X1 |
XM_011241370.2 | XP_011239672.1 | deoxyguanosine kinase, mitochondrial isoform X1 |
NM_013764.2 | NP_038792.2 | deoxyguanosine kinase, mitochondrial isoform 1 |
XM_017321604.1 | XP_017177093.1 | deoxyguanosine kinase, mitochondrial isoform X1 |
NM_001162521.1 | NP_001155993.1 | deoxyguanosine kinase, mitochondrial isoform 2 |
Homo sapiens (human) | DGUOK | NP_550438.1 |
DGUOK | XP_001107072.1 | |
Canis lupus familiaris (dog) | DGUOK | XP_533001.3 |
Rattus norvegicus (Norway rat) | Dguok | NP_001100072.1 |
Danio rerio (zebrafish) | dguok | NP_001093561.1 |
Danio rerio (zebrafish) | LOC100331914 | XP_002662248.1 |
Oryza sativa (rice) | Os01g0874100 | NP_001044956.1 |
Bos taurus (cattle) | DGUOK | NP_001014888.2 |
Pan troglodytes (chimpanzee) | DGUOK | XP_001153473.1 |
Mus musculus (house mouse) | Dguok | NP_038792.2 |
Arabidopsis thaliana (thale cress) | AT1G72040 | NP_565032.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100494916 | XP_002938121.1 |
Mitochondrial thymidine kinase 2 but not deoxyguanosine kinase is up-regulated during the stationary growth phase of cultured cells.
Sun R, Eriksson S, Wang L
Nucleosides, nucleotides & nucleic acids33(4-6)282-6(2014)
Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set.
VanBuren V, Piao Y, Dudekula DB, Qian Y, Carter MG, Martin PR, Stagg CA, Bassey UC, Aiba K, Hamatani T, Kargul GJ, Luo AG, Kelso J, Hide W, Ko MS
Genome research12(12)1999-2003(2002 Dec)
Exposure-disease continuum for 2-chloro-2'-deoxyadenosine, a prototype ocular teratogen. 1. Dose-response analysis.
Wubah JA, Setzer RW, Lau C, Charlap JH, Knudsen TB
Teratology64(3)154-69(2001 Sep)
Cloning and characterization of mouse deoxyguanosine kinase. Evidence for a cytoplasmic isoform.
Petrakis TG, Ktistaki E, Wang L, Eriksson S, Talianidis I
The Journal of biological chemistry274(35)24726-30(1999 Aug)
Secondary loss of deoxyguanosine kinase activity in purine nucleoside phosphorylase deficient mice.
Snyder FF, Jenuth JP, Dilay JE, Fung E, Lightfoot T, Mably ER
Biochimica et biophysica acta1227(1-2)33-40(1994 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
thymidine kinase 2 but not deoxyguanosine kinase is up-regulated during the stationary growth phase of cultured cells
Title: Mitochondrial thymidine kinase 2 but not deoxyguanosine kinase is up-regulated during the stationary growth phase of cultured cells.
The following Dguok gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dguok cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu13135 | |
Clone ID Related Accession (Same CDS sequence) | NM_001162521.1 | |
Accession Version | NM_001162521.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Mus musculus(house mouse) | |
Product | deoxyguanosine kinase, mitochondrial isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ560618.1, BQ746075.1 and AV026535.1. Transcript Variant: This variant (2), known as dGK-3, lacks an exon in the coding region, which results in a frameshift and an early stop codon compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC094920.1, AY037862.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTGCAG GTCGGTTCCT TCTGCGTCGT CTCCGAGCGT CTTTCCGTTC CCCGCTGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001155993.1 |
CDS | 81..791 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCTGCAG GTCGGTTCCT TCTGCGTCGT CTCCGAGCGT CTTTCCGTTC CCCGCTGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu13153 | |
Clone ID Related Accession (Same CDS sequence) | NM_013764.2 | |
Accession Version | NM_013764.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Mus musculus(house mouse) | |
Product | deoxyguanosine kinase, mitochondrial isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ560618.1, AK035281.1 and AV026535.1. On Jul 2, 2009 this sequence version replaced NM_013764.1. Transcript Variant: This variant (1), known as dGK-1, represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK035281.1, BC012647.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTGCAG GTCGGTTCCT TCTGCGTCGT CTCCGAGCGT CTTTCCGTTC CCCGCTGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_038792.2 |
CDS | 81..914 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTGCAG GTCGGTTCCT TCTGCGTCGT CTCCGAGCGT CTTTCCGTTC CCCGCTGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69283 | |
Clone ID Related Accession (Same CDS sequence) | XM_017321604.2 , XM_011241370.2 , XM_017321604.1 | |
Accession Version | XM_011241370.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | deoxyguanosine kinase, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011241370.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGTACC AGGAGCCAGC ACGATGGTCC TACACATTCC AGACCCTTTC TTTCATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239672.1 |
CDS | 791..1333 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGATGTACC AGGAGCCAGC ACGATGGTCC TACACATTCC AGACCCTTTC TTTCATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69283 | |
Clone ID Related Accession (Same CDS sequence) | XM_017321604.2 , XM_011241370.2 , XM_017321604.1 | |
Accession Version | XM_017321604.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | deoxyguanosine kinase, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGTACC AGGAGCCAGC ACGATGGTCC TACACATTCC AGACCCTTTC TTTCATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017177093.1 |
CDS | 229..771 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGATGTACC AGGAGCCAGC ACGATGGTCC TACACATTCC AGACCCTTTC TTTCATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69283 | |
Clone ID Related Accession (Same CDS sequence) | XM_017321604.2 , XM_011241370.2 , XM_017321604.1 | |
Accession Version | XM_017321604.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | deoxyguanosine kinase, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017321604.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGTACC AGGAGCCAGC ACGATGGTCC TACACATTCC AGACCCTTTC TTTCATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017177093.1 |
CDS | 232..774 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGATGTACC AGGAGCCAGC ACGATGGTCC TACACATTCC AGACCCTTTC TTTCATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mitochondrial thymidine kinase 2 but not deoxyguanosine kinase is up-regulated during the stationary growth phase of cultured cells. |
Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. |
Exposure-disease continuum for 2-chloro-2'-deoxyadenosine, a prototype ocular teratogen. 1. Dose-response analysis. |
Cloning and characterization of mouse deoxyguanosine kinase. Evidence for a cytoplasmic isoform. |
Secondary loss of deoxyguanosine kinase activity in purine nucleoside phosphorylase deficient mice. |